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Search term: YIL072W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HOP1
SGD link S000001334
Alternative ID YIL072W
Description Meiosis-specific DNA binding protein that displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for homologous chromosome synapsis and chiasma formation
Synonyms YIL072W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4652 AC-HY--

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING HORMA domain

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g67370 GI:15220427
Arabidopsis thaliana (Ath) At4g32200_1 GI:15236708
Caenorhabditis elegans (Cel) CE07625
(WBGene00001862)		 GI:17541082 Q23472
Caenorhabditis elegans (Cel) CE10290 GI:17540342
Caenorhabditis elegans (Cel) CE11330_1 GI:17507769 O01820
Caenorhabditis elegans (Cel) CE27529_1 GI:17544088
Homo sapiens (Hsa) Hs18549128 GI:18549128
Homo sapiens (Hsa) Hs22057577 GI:22057577
Homo sapiens (Hsa) Hs22068642 GI:22068642
Saccharomyces cerevisiae (Sce) YIL072w
(S000001334)		 GI:6322118 P20050


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
CelWBGene00002034
GO:0000794 condensed nuclear chromosome C
IDA
AthAt1g67370
CelWBGene00001862
WBGene00002034
SceS000001334
GO:0000800 lateral element C
IPI
SceS000001334
GO:0005634 nucleus C
IDA
CelWBGene00002034
GO:0000400 four-way junction DNA binding F
IDA
SceS000001334
GO:0003677 DNA binding F
IDA
CelWBGene00001862
ISS
AthAt4g32200
At1g67370
GO:0000003 reproduction P
IMP
CelWBGene00002034
GO:0002119 nematode larval development P
IMP
CelWBGene00002034
GO:0007062 sister chromatid cohesion P
TAS
CelWBGene00001862
GO:0007129 synapsis P
IDA
AthAt1g67370
IMP
AthAt1g67370
CelWBGene00002034
SceS000001334
GO:0007130 synaptonemal complex assembly P
IMP
CelWBGene00001862
SceS000001334
TAS
AthAt4g32200
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00002034
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001862
WBGene00002034
GO:0040007 growth P
IMP
CelWBGene00002034
GO:0042138 meiotic DNA double-strand break
formation		 P
IGI
CelWBGene00002034
IMP
CelWBGene00002034
GO:0045132 meiotic chromosome segregation P
IMP
CelWBGene00001862
WBGene00002034
GO:0045143 homologous chromosome segregation P
IMP
CelWBGene00001862
GO:0051026 chiasma assembly P
IMP
AthAt1g67370
GO:0051598 meiotic recombination checkpoint P
IGI
SceS000001334

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39319

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) HOP1
(S000001334)		 GI:6322118 P20050
Kluyveromyces lactis (Kla) KLLA0C07623g GI:50305161
Eremothecium gossypii (Ego) AGOS_ACL029W GI:45185659


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
SceS000001334
GO:0000800 lateral element C
IPI
SceS000001334
GO:0000400 four-way junction DNA binding F
IDA
SceS000001334
GO:0007129 synapsis P
IMP
SceS000001334
GO:0007130 synaptonemal complex assembly P
IMP
SceS000001334
GO:0051598 meiotic recombination checkpoint P
IGI
SceS000001334

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1999

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1020 ACL029W
Arabidopsis thaliana (Ath) ath5971 At1g67370.1
Caenorhabditis elegans (Cel) cel21871 ZK381.1
(CE07625;
WBGene00001862)
Candida glabrata (Cgl) cgl5212 CAGL0M12771g
Cryptococcus neoformans (Cne) cne3507 176.m02231
Debaryomyces hansenii (Dha) dha3019 DEHA0D16060g
Danio rerio (Dre) dre10750 ENSDARP00000023976
Danio rerio (Dre) dre7372 ENSDARP00000027529
Danio rerio (Dre) dre7364 ENSDARP00000045271
Takifugu rubripes (Fru) fru1292 SINFRUP00000135522
Takifugu rubripes (Fru) fru18314 SINFRUP00000158093
Gallus gallus (Gga) gga7605 ENSGALP00000013025
(HORMAD2)
Gallus gallus (Gga) gga7606 ENSGALP00000013026
Gallus gallus (Gga) gga7607 ENSGALP00000013027
Gallus gallus (Gga) gga23882 ENSGALP00000023568
(HORMAD1)
Gallus gallus (Gga) gga23883 ENSGALP00000023569
Gallus gallus (Gga) gga23884 ENSGALP00000023570
Homo sapiens (Hsa) hsa1962 ENSP00000326489
(HORMAD1)		 Q86X24-2
Homo sapiens (Hsa) hsa21475 ENSP00000336984
(HORMAD2)		 Q8N7B1
Homo sapiens (Hsa) hsa21476 ENSP00000346194
Homo sapiens (Hsa) hsa1961 ENSP00000355167
(HORMAD1)		 Q86X24-1
Kluyveromyces lactis (Kla) kla1538 KLLA0C07623g
Mus musculus (Mmu) mmu3185 ENSMUSP00000020689
(MGI:1923078)		 Q5SQP1-2
Mus musculus (Mmu) mmu17149 ENSMUSP00000029754
(MGI:1915231)		 Q9D5T7-1
Oryza sativa (Osa) osa72678 7229.m00159
Plasmodium falciparum (Pfa) pfa4153 PF13_0050
Rattus norvegicus (Rno) rno16611 ENSRNOP00000028735
(RGD:1564960)
Saccharomyces cerevisiae (Sce) sce3091 YIL072W
(S000001334)
Schizosaccharomyces pombe (Spo) spo4382 SPBC1718.02 Q9P7P2


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
AthAt1g67370
CelWBGene00001862
SceS000001334
GO:0000800 lateral element C
IPI
SceS000001334
GO:0005575 cellular_component C
ND
MmuMGI:1915231
MGI:1923078
GO:0030998 linear element C
IDA
SpoSPBC1718.02
GO:0000400 four-way junction DNA binding F
IDA
SceS000001334
GO:0003674 molecular_function F
ND
MmuMGI:1915231
MGI:1923078
GO:0003677 DNA binding F
IDA
CelWBGene00001862
ISS
AthAt1g67370
SpoSPBC1718.02
GO:0019787 small conjugating protein ligase
activity		 F
ISS
SpoSPBC1718.02
GO:0007062 sister chromatid cohesion P
TAS
CelWBGene00001862
GO:0007129 synapsis P
IDA
AthAt1g67370
IMP
AthAt1g67370
SceS000001334
GO:0007130 synaptonemal complex assembly P
IMP
CelWBGene00001862
SceS000001334
GO:0008150 biological_process P
ND
MmuMGI:1923078
MGI:1915231
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001862
GO:0045132 meiotic chromosome segregation P
IMP
CelWBGene00001862
GO:0045143 homologous chromosome segregation P
IMP
CelWBGene00001862
GO:0051026 chiasma assembly P
IMP
AthAt1g67370
GO:0051598 meiotic recombination checkpoint P
IGI
SceS000001334

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC1718.02
(Q9P7P2)		 YIL072W
(S000001334)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
SceS000001334
GO:0000800 lateral element C
IPI
SceS000001334
GO:0030998 linear element C
IDA
SpoSPBC1718.02
GO:0000400 four-way junction DNA binding F
IDA
SceS000001334
GO:0003677 DNA binding F
ISS
SpoSPBC1718.02
GO:0019787 small conjugating protein ligase
activity		 F
ISS
SpoSPBC1718.02
GO:0007129 synapsis P
IMP
SceS000001334
GO:0007130 synaptonemal complex assembly P
IMP
SceS000001334
GO:0051598 meiotic recombination checkpoint P
IGI
SceS000001334

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GO info in one table:

s.khadayate@ucl.ac.uk