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Search term: YIL103W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DPH1
SGD link S000001365
Alternative ID YIL103W
Description Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph2p and Kti11p
Synonyms YIL103W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2648 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Diphthamide biosynthesis protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g59630 GI:15231723
Arabidopsis thaliana (Ath) At5g62030 GI:15240408
Caenorhabditis elegans (Cel) CE15608
(WBGene00007488)		 GI:17531715 Q09454
Caenorhabditis elegans (Cel) CE17401
(WBGene00007576)		 GI:17552166 P49958
Drosophila melanogaster (Dme) 7294688 GI:7294688 Q9VTM2
Drosophila melanogaster (Dme) 7299937 GI:7299937
Homo sapiens (Hsa) Hs21536476 GI:14742688
Homo sapiens (Hsa) Hs4503361 GI:4503361
Homo sapiens (Hsa) HsM4557533 GI:4557533
Saccharomyces cerevisiae (Sce) YIL103w
(S000001365)		 GI:6322088 P40487
Saccharomyces cerevisiae (Sce) YKL191w
(S000001674)		 GI:6322657 P32461
Schizosaccharomyces pombe (Spo) SPBC17D1.02 GI:19113176 Q10206
Schizosaccharomyces pombe (Spo) SPBC3B8.05 GI:19113201 O59713
Encephalitozoon cuniculi (Ecu) ECU07g0980 GI:19074520 Q8SUZ5


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g59630
At5g62030
GO:0005634 nucleus C
IDA
SpoSPBC3B8.05
GO:0005737 cytoplasm C
IDA
SceS000001674
S000001365
ISS
SpoSPBC3B8.05
SPBC17D1.02
GO:0005829 cytosol C
IDA
SpoSPBC3B8.05
SPBC17D1.02
GO:0003674 molecular_function F
ND
AthAt5g62030
At3g59630
SceS000001365
S000001674
SpoSPBC17D1.02
SPBC3B8.05
GO:0000003 reproduction P
IMP
CelWBGene00007576
GO:0002119 nematode larval development P
IMP
CelWBGene00007576
GO:0006417 regulation of translation P
IC
SpoSPBC17D1.02
SPBC3B8.05
GO:0008150 biological_process P
ND
AthAt5g62030
At3g59630
GO:0017183 peptidyl-diphthamide biosynthetic process from
peptidyl-histidine		 P
IMP
SceS000001365
S000001674
ISS
SpoSPBC3B8.05
SPBC17D1.02
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000001365
S000001674
GO:0040002 collagen and cuticulin-based cuticle
development		 P
IMP
CelWBGene00007488
GO:0040007 growth P
IMP
CelWBGene00007576
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007576

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1059

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DPH1 GI:116686106
Pan troglodytes (Ptr) DPH1-OVCA2 GI:114665638
Canis familiaris (Cfa) LOC480653 GI:73967371
Mus musculus (Mmu) Dph1
(MGI:2151233)		 GI:118026919 Q5NCQ5
Rattus norvegicus (Rno) Dph1 GI:109488539
Gallus gallus (Gga) DPH1 GI:71897063
Drosophila melanogaster (Dme) CG11652
(FBgn0036194)		 GI:21356957
Caenorhabditis elegans (Cel) C14B1.5
(CE17401;
WBGene00007576)		 GI:17552166 P49958
Schizosaccharomyces pombe (Spo) SPBC3B8.05 GI:19113201 O59713
Saccharomyces cerevisiae (Sce) DPH1
(S000001365)		 GI:6322088 P40487
Kluyveromyces lactis (Kla) KLLA0F03971g GI:50310481
Eremothecium gossypii (Ego) AGOS_ADL229W GI:45187644
Magnaporthe grisea (Mgr) MGG_03237 GI:145608282
Neurospora crassa (Ncr) NCU08503.1 GI:32418140
Arabidopsis thaliana (Ath) AT5G62030 GI:15240408
Oryza sativa (Osa) Os02g0815600 GI:115449593
Plasmodium falciparum (Pfa) PF14_0136 GI:124808425


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g62030
PfaPF14_0136
GO:0005634 nucleus C
IDA
SpoSPBC3B8.05
GO:0005737 cytoplasm C
IDA
SceS000001365
ISS
SpoSPBC3B8.05
GO:0005829 cytosol C
IDA
SpoSPBC3B8.05
GO:0003674 molecular_function F
ND
AthAt5g62030
PfaPF14_0136
SceS000001365
SpoSPBC3B8.05
GO:0005515 protein binding F
IPI
MmuMGI:2151233
GO:0000003 reproduction P
IMP
CelWBGene00007576
GO:0002119 nematode larval development P
IMP
CelWBGene00007576
GO:0006412 translation P
TAS
HsaDPH1
GO:0006417 regulation of translation P
IC
SpoSPBC3B8.05
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0036194
GO:0008150 biological_process P
ND
AthAt5g62030
PfaPF14_0136
GO:0008283 cell proliferation P
IMP
MmuMGI:2151233
GO:0017183 peptidyl-diphthamide biosynthetic process from
peptidyl-histidine		 P
IMP
SceS000001365
ISS
SpoSPBC3B8.05
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000001365
GO:0040007 growth P
IMP
CelWBGene00007576
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007576

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1378

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8652 ENSANGP00000025475
Anopheles gambiae (Aga) aga14173 ENSANGP00000026830
Ashbya gossypii (Ago) ago1512 ADL229W
Arabidopsis thaliana (Ath) ath28308 At5g62030.1
Caenorhabditis elegans (Cel) cel1949 C14B1.5
(CE17401;
WBGene00007576)
Candida glabrata (Cgl) cgl1744 CAGL0G02761g
Cryptococcus neoformans (Cne) cne2445 181.m08480
Dictyostelium discoideum (Ddi) ddi9079 DDB0185929
Debaryomyces hansenii (Dha) dha3743 DEHA0E11352g
Drosophila melanogaster (Dme) dme9109 CG11652-PA
(FBgn0036194)
Drosophila melanogaster (Dme) dme9110 CG11652-PB
(FBgn0036194)
Encephalitozoon cuniculi (Ecu) ecu1906 19074520
Takifugu rubripes (Fru) fru6467 SINFRUP00000162943
Takifugu rubripes (Fru) fru6465 SINFRUP00000162944
Takifugu rubripes (Fru) fru6466 SINFRUP00000169105
Gallus gallus (Gga) gga8867 ENSGALP00000004864
(DPH1)		 Q5ZHX9
Homo sapiens (Hsa) hsa12782 ENSP00000263083
(DPH1)		 Q9BZG8-1
Kluyveromyces lactis (Kla) kla4260 KLLA0F03971g
Mus musculus (Mmu) mmu4232 ENSMUSP00000042162
(MGI:2151233)		 Q5NCQ5
Neurospora crassa (Ncr) ncr8285 NCU08503.2
Oryza sativa (Osa) osa22366 3703.m00144
Oryza sativa (Osa) osa29939 4292.m00257
Oryza sativa (Osa) osa29949 4292.m00300
Oryza sativa (Osa) osa32677 4467.m00229
Plasmodium falciparum (Pfa) pfa1464 PF14_0136
Rattus norvegicus (Rno) rno5561 ENSRNOP00000004161
(RGD:1562694)		 B2RYK2
Saccharomyces cerevisiae (Sce) sce3123 YIL103W
(S000001365)
Schizosaccharomyces pombe (Spo) spo2005 SPBC3B8.05 O59713
Yarrowia lipolytica (Yli) yli6274 YALI0F22055g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g62030
PfaPF14_0136
GO:0005634 nucleus C
IDA
SpoSPBC3B8.05
GO:0005737 cytoplasm C
IDA
SceS000001365
ISS
SpoSPBC3B8.05
GO:0005829 cytosol C
IDA
SpoSPBC3B8.05
GO:0003674 molecular_function F
ND
AthAt5g62030
PfaPF14_0136
SceS000001365
SpoSPBC3B8.05
GO:0005515 protein binding F
IPI
MmuMGI:2151233
GO:0000003 reproduction P
IMP
CelWBGene00007576
GO:0002119 nematode larval development P
IMP
CelWBGene00007576
GO:0006417 regulation of translation P
IC
SpoSPBC3B8.05
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0036194
GO:0008150 biological_process P
ND
AthAt5g62030
PfaPF14_0136
GO:0008283 cell proliferation P
IMP
MmuMGI:2151233
GO:0017183 peptidyl-diphthamide biosynthetic process from
peptidyl-histidine		 P
IMP
SceS000001365
ISS
SpoSPBC3B8.05
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000001365
GO:0040007 growth P
IMP
CelWBGene00007576
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007576

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC3B8.05
(O59713)		 YIL103W
(S000001365)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC3B8.05
GO:0005737 cytoplasm C
IDA
SceS000001365
ISS
SpoSPBC3B8.05
GO:0005829 cytosol C
IDA
SpoSPBC3B8.05
GO:0003674 molecular_function F
ND
SceS000001365
SpoSPBC3B8.05
GO:0006417 regulation of translation P
IC
SpoSPBC3B8.05
GO:0017183 peptidyl-diphthamide biosynthetic process from
peptidyl-histidine		 P
IMP
SceS000001365
ISS
SpoSPBC3B8.05
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000001365

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GO info in one table:

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