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Search term: YIL106W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MOB1
SGD link S000001368
Alternative ID YIL106W
Description Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex
Synonyms YIL106W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0440 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Cell cycle-associated protein Mob1-1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g19050_2 GI:15234110
Arabidopsis thaliana (Ath) At5g20430 GI:15241354
Arabidopsis thaliana (Ath) At5g20440 GI:15241355
Arabidopsis thaliana (Ath) At5g45550 GI:15242430
Caenorhabditis elegans (Cel) CE10076 GI:17540310
Caenorhabditis elegans (Cel) CE18579
(WBGene00008601)		 GI:17551518 Q7JLW3
Caenorhabditis elegans (Cel) CE18580 GI:17551516 Q7JLW3
Caenorhabditis elegans (Cel) CE26804 GI:17551520 Q7JLW3
Drosophila melanogaster (Dme) 7294714 GI:7294714
Drosophila melanogaster (Dme) 7294715 GI:7294715
Drosophila melanogaster (Dme) 7300852 GI:7300852
Homo sapiens (Hsa) Hs22043549 GI:22043549
Homo sapiens (Hsa) Hs8922671 GI:8922671
Saccharomyces cerevisiae (Sce) YFL034c-b
(S000001859)		 GI:14318483 P43563
Saccharomyces cerevisiae (Sce) YIL106w
(S000001368)		 GI:6681848 P40484
Schizosaccharomyces pombe (Spo) SPBC428.13c GI:19111983 O94360
Schizosaccharomyces pombe (Spo) SPCC970.04c GI:19075351 O74558
Arabidopsis thaliana (Ath) At4g19050_2 GI:15234110
Arabidopsis thaliana (Ath) At5g20430 GI:15241354
Arabidopsis thaliana (Ath) At5g20440 GI:15241355
Arabidopsis thaliana (Ath) At5g45550 GI:15242430
Caenorhabditis elegans (Cel) CE10076 GI:17540310
Caenorhabditis elegans (Cel) CE18579
(WBGene00008601)		 GI:17551518 Q7JLW3
Caenorhabditis elegans (Cel) CE18580 GI:17551516 Q7JLW3
Caenorhabditis elegans (Cel) CE26804 GI:17551520 Q7JLW3
Drosophila melanogaster (Dme) 7294714 GI:7294714
Drosophila melanogaster (Dme) 7294715 GI:7294715
Drosophila melanogaster (Dme) 7300852 GI:7300852
Homo sapiens (Hsa) Hs22043549 GI:22043549
Homo sapiens (Hsa) Hs8922671 GI:8922671
Saccharomyces cerevisiae (Sce) YFL034c-b
(S000001859)		 GI:14318483 P43563
Saccharomyces cerevisiae (Sce) YIL106w
(S000001368)		 GI:6681848 P40484
Schizosaccharomyces pombe (Spo) SPBC428.13c GI:19111983 O94360
Schizosaccharomyces pombe (Spo) SPCC970.04c GI:19075351 O74558
Arabidopsis thaliana (Ath) At4g19050_2 GI:15234110
Arabidopsis thaliana (Ath) At5g20430 GI:15241354
Arabidopsis thaliana (Ath) At5g20440 GI:15241355
Arabidopsis thaliana (Ath) At5g45550 GI:15242430
Caenorhabditis elegans (Cel) CE10076 GI:17540310
Caenorhabditis elegans (Cel) CE18579
(WBGene00008601)		 GI:17551518 Q7JLW3
Caenorhabditis elegans (Cel) CE18580 GI:17551516 Q7JLW3
Caenorhabditis elegans (Cel) CE26804 GI:17551520 Q7JLW3
Drosophila melanogaster (Dme) 7294714 GI:7294714
Drosophila melanogaster (Dme) 7294715 GI:7294715
Drosophila melanogaster (Dme) 7300852 GI:7300852
Homo sapiens (Hsa) Hs22043549 GI:22043549
Homo sapiens (Hsa) Hs8922671 GI:8922671
Saccharomyces cerevisiae (Sce) YFL034c-b
(S000001859)		 GI:14318483 P43563
Saccharomyces cerevisiae (Sce) YIL106w
(S000001368)		 GI:6681848 P40484
Schizosaccharomyces pombe (Spo) SPBC428.13c GI:19111983 O94360
Schizosaccharomyces pombe (Spo) SPCC970.04c GI:19075351 O74558


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
RCA
SceS000001368
GO:0000793 condensed chromosome C
RCA
SceS000001368
GO:0000794 condensed nuclear chromosome C
RCA
SceS000001368
GO:0005575 cellular_component C
ND
AthAt4g19050
GO:0005634 nucleus C
IDA
AthAt5g20440
At5g45550
At5g20430
SceS000001859
SpoSPBC428.13c
GO:0005737 cytoplasm C
IDA
SpoSPCC970.04c
GO:0005816 spindle pole body C
IDA
SceS000001368
SpoSPBC428.13c
GO:0005829 cytosol C
IDA
SpoSPBC428.13c
GO:0005933 cellular bud C
IDA
SceS000001859
GO:0005934 cellular bud tip C
IDA
SceS000001859
GO:0005935 cellular bud neck C
IDA
SceS000001859
S000001368
GO:0005938 cell cortex C
IDA
SpoSPCC970.04c
GO:0009524 phragmoplast C
IDA
AthAt5g20430
GO:0031097 medial cortex C
IDA
SpoSPBC428.13c
GO:0032153 cell division site C
IDA
SpoSPCC970.04c
SPBC428.13c
GO:0034973 Sid2-Mob1 complex C
IPI
SpoSPBC428.13c
GO:0043332 mating projection tip C
IDA
SceS000001859
GO:0044427 chromosomal part C
RCA
SceS000001368
GO:0044454 nuclear chromosome part C
RCA
SceS000001368
GO:0051286 cell tip C
IDA
SpoSPCC970.04c
GO:0005515 protein binding F
IPI
SpoSPBC428.13c
SPCC970.04c
GO:0008047 enzyme activator activity F
RCA
SceS000001368
GO:0019207 kinase regulator activity F
IDA
SceS000001368
GO:0019209 kinase activator activity F
RCA
SceS000001368
GO:0019887 protein kinase regulator activity F
IGI
SpoSPBC428.13c
GO:0030295 protein kinase activator activity F
IDA
SceS000001859
ISS
SpoSPCC970.04c
GO:0000278 mitotic cell cycle P
RCA
SceS000001368
GO:0000279 M phase P
RCA
SceS000001368
GO:0000280 nuclear division P
RCA
SceS000001368
GO:0006414 translational elongation P
RCA
SceS000001368
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPCC970.04c
IDA
SceS000001859
S000001368
GO:0007096 regulation of exit from mitosis P
IMP
SceS000001859
TAS
SceS000001368
GO:0007118 budding cell apical bud growth P
IGI
SceS000001859
IMP
SceS000001859
GO:0007163 establishment or maintenance of cell
polarity		 P
IMP
SceS000001859
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPCC970.04c
GO:0008150 biological_process P
ND
AthAt5g20430
At5g20440
At5g45550
GO:0031031 positive regulation of septation initiation
signaling		 P
IMP
SpoSPBC428.13c
GO:0034613 cellular protein localization P
IGI
SpoSPBC428.13c
GO:0042327 positive regulation of phosphorylation P
ISS
SpoSPCC970.04c
GO:0045859 regulation of protein kinase activity P
IGI
SpoSPBC428.13c
GO:0048285 organelle fission P
RCA
SceS000001368
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000001368

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
10076

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MOBKL1B GI:148747437
Pan troglodytes (Ptr) MOBKL1B GI:55606148
Canis familiaris (Cfa) MOBKL1B GI:73980519
Mus musculus (Mmu) Mobkl1b
(MGI:2442631)		 GI:21704148 Q921Y0
Rattus norvegicus (Rno) Mobkl1b GI:76559917
Schizosaccharomyces pombe (Spo) mob1
(SPBC428.13c)		 GI:19111983 O94360
Saccharomyces cerevisiae (Sce) MOB1
(S000001368)		 GI:6681848 P40484
Kluyveromyces lactis (Kla) KLLA0F03795g GI:50310465
Eremothecium gossypii (Ego) AGOS_ADL236W GI:45187637
Magnaporthe grisea (Mgr) MGG_03151 GI:145608394
Neurospora crassa (Ncr) NCU01605.1 GI:32415129
Arabidopsis thaliana (Ath) AT4G19050 GI:15234110
Oryza sativa (Osa) Os10g0396300 GI:115481876


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
RCA
SceS000001368
GO:0000793 condensed chromosome C
RCA
SceS000001368
GO:0000794 condensed nuclear chromosome C
RCA
SceS000001368
GO:0005575 cellular_component C
ND
AthAt4g19050
GO:0005634 nucleus C
IDA
SpoSPBC428.13c
GO:0005816 spindle pole body C
IDA
SceS000001368
SpoSPBC428.13c
GO:0005829 cytosol C
IDA
SpoSPBC428.13c
GO:0005935 cellular bud neck C
IDA
SceS000001368
GO:0031097 medial cortex C
IDA
SpoSPBC428.13c
GO:0032153 cell division site C
IDA
SpoSPBC428.13c
GO:0034973 Sid2-Mob1 complex C
IPI
SpoSPBC428.13c
GO:0044427 chromosomal part C
RCA
SceS000001368
GO:0044454 nuclear chromosome part C
RCA
SceS000001368
GO:0005515 protein binding F
IPI
HsaMOBKL1B
SpoSPBC428.13c
GO:0008047 enzyme activator activity F
RCA
SceS000001368
GO:0019207 kinase regulator activity F
IDA
SceS000001368
GO:0019209 kinase activator activity F
RCA
SceS000001368
GO:0019887 protein kinase regulator activity F
IGI
SpoSPBC428.13c
GO:0000278 mitotic cell cycle P
RCA
SceS000001368
GO:0000279 M phase P
RCA
SceS000001368
GO:0000280 nuclear division P
RCA
SceS000001368
GO:0006414 translational elongation P
RCA
SceS000001368
GO:0006468 protein amino acid phosphorylation P
IDA
SceS000001368
GO:0007096 regulation of exit from mitosis P
TAS
SceS000001368
GO:0031031 positive regulation of septation initiation
signaling		 P
IMP
SpoSPBC428.13c
GO:0034613 cellular protein localization P
IGI
SpoSPBC428.13c
GO:0035329 hippo signaling cascade P
IDA
HsaMOBKL1B
GO:0045859 regulation of protein kinase activity P
IGI
SpoSPBC428.13c
GO:0048285 organelle fission P
RCA
SceS000001368
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000001368

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1100

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4176 ENSANGP00000019898
Anopheles gambiae (Aga) aga9805 ENSANGP00000025093
Ashbya gossypii (Ago) ago1505 ADL236W
Arabidopsis thaliana (Ath) ath26404 At5g45550.1
Caenorhabditis elegans (Cel) cel15338 T12B3.4
(CE21179;
WBGene00020447)
Candida glabrata (Cgl) cgl1746 CAGL0G02805g
Dictyostelium discoideum (Ddi) ddi9978 DDB0184547
Dictyostelium discoideum (Ddi) ddi6579 DDB0206275
Debaryomyces hansenii (Dha) dha295 DEHA0A06677g
Drosophila melanogaster (Dme) dme13846 CG13852-PA
(FBgn0038965)
Drosophila melanogaster (Dme) dme1760 CG4946-PA
(FBgn0032203)
Danio rerio (Dre) dre19747 ENSDARP00000007370
(mobkl1a)		 Q7ZV94
Danio rerio (Dre) dre22623 ENSDARP00000021765
(zgc:77552)		 Q6NX95
Takifugu rubripes (Fru) fru9935 SINFRUP00000150734
Takifugu rubripes (Fru) fru10539 SINFRUP00000155283
Takifugu rubripes (Fru) fru21642 SINFRUP00000157959
Gallus gallus (Gga) gga28134 ENSGALP00000002871
Gallus gallus (Gga) gga17747 ENSGALP00000018856
(MOBKL1A)
Homo sapiens (Hsa) hsa31108 ENSP00000262244
(MOBKL2B)		 Q86TA1
Homo sapiens (Hsa) hsa18016 ENSP00000264089
(MOBKL1B)		 B7WP91
Homo sapiens (Hsa) hsa24204 ENSP00000310189
(MOBKL1A)		 Q7L9L4
Homo sapiens (Hsa) hsa15254 ENSP00000349575
(MOBKL2A)		 Q96BX8
Kluyveromyces lactis (Kla) kla4252 KLLA0F03795g
Mus musculus (Mmu) mmu2530 ENSMUSP00000003438
(MGI:3050117)		 Q8BSU7
Mus musculus (Mmu) mmu20331 ENSMUSP00000006424
(MGI:1915723)		 Q8BPB0
Mus musculus (Mmu) mmu22188 ENSMUSP00000039115
(MGI:2442631)		 Q921Y0-2
Mus musculus (Mmu) mmu17944 ENSMUSP00000043547
Mus musculus (Mmu) mmu22190 ENSMUSP00000069216
Neurospora crassa (Ncr) ncr1559 NCU01605.2
Oryza sativa (Osa) osa5103 2346.m00142
Oryza sativa (Osa) osa5284 2348.m00210
Oryza sativa (Osa) osa85238 8373.m00140
Oryza sativa (Osa) osa85852 8750.m00243
Rattus norvegicus (Rno) rno22943 ENSRNOP00000012519
(RGD:1560696)
Rattus norvegicus (Rno) rno10167 ENSRNOP00000014650
(RGD:1305114)
Rattus norvegicus (Rno) rno26241 ENSRNOP00000025634
(RGD:1308187)		 B5DEX8
Saccharomyces cerevisiae (Sce) sce3127 YIL106W
(S000001368)
Schizosaccharomyces pombe (Spo) spo1067 SPBC428.13c O94360
Yarrowia lipolytica (Yli) yli3064 YALI0D08580g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
RCA
SceS000001368
GO:0000793 condensed chromosome C
RCA
SceS000001368
GO:0000794 condensed nuclear chromosome C
RCA
SceS000001368
GO:0005575 cellular_component C
ND
DmeFBgn0038965
MmuMGI:3050117
GO:0005634 nucleus C
IDA
AthAt5g45550
SpoSPBC428.13c
GO:0005816 spindle pole body C
IDA
SceS000001368
SpoSPBC428.13c
GO:0005829 cytosol C
IDA
SpoSPBC428.13c
GO:0005935 cellular bud neck C
IDA
SceS000001368
GO:0031097 medial cortex C
IDA
SpoSPBC428.13c
GO:0032153 cell division site C
IDA
SpoSPBC428.13c
GO:0034973 Sid2-Mob1 complex C
IPI
SpoSPBC428.13c
GO:0044427 chromosomal part C
RCA
SceS000001368
GO:0044454 nuclear chromosome part C
RCA
SceS000001368
GO:0003674 molecular_function F
ND
MmuMGI:3050117
GO:0005515 protein binding F
IPI
DmeFBgn0038965
SpoSPBC428.13c
GO:0008047 enzyme activator activity F
RCA
SceS000001368
GO:0019207 kinase regulator activity F
IDA
SceS000001368
GO:0019209 kinase activator activity F
RCA
SceS000001368
GO:0019887 protein kinase regulator activity F
IGI
SpoSPBC428.13c
GO:0000278 mitotic cell cycle P
RCA
SceS000001368
GO:0000279 M phase P
RCA
SceS000001368
GO:0000280 nuclear division P
RCA
SceS000001368
GO:0006414 translational elongation P
RCA
SceS000001368
GO:0006468 protein amino acid phosphorylation P
IDA
SceS000001368
GO:0006915 apoptosis P
IMP
DmeFBgn0038965
GO:0007096 regulation of exit from mitosis P
TAS
SceS000001368
GO:0007165 signal transduction P
IMP
DmeFBgn0038965
GO:0008150 biological_process P
ND
AthAt5g45550
MmuMGI:3050117
GO:0008283 cell proliferation P
IMP
DmeFBgn0038965
GO:0031031 positive regulation of septation initiation
signaling		 P
IMP
SpoSPBC428.13c
GO:0034613 cellular protein localization P
IGI
SpoSPBC428.13c
GO:0045859 regulation of protein kinase activity P
IGI
SpoSPBC428.13c
GO:0048285 organelle fission P
RCA
SceS000001368
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000001368

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC428.13c
(O94360)		 YIL106W
(S000001368)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
RCA
SceS000001368
GO:0000793 condensed chromosome C
RCA
SceS000001368
GO:0000794 condensed nuclear chromosome C
RCA
SceS000001368
GO:0005634 nucleus C
IDA
SpoSPBC428.13c
GO:0005816 spindle pole body C
IDA
SceS000001368
SpoSPBC428.13c
GO:0005829 cytosol C
IDA
SpoSPBC428.13c
GO:0005935 cellular bud neck C
IDA
SceS000001368
GO:0031097 medial cortex C
IDA
SpoSPBC428.13c
GO:0032153 cell division site C
IDA
SpoSPBC428.13c
GO:0034973 Sid2-Mob1 complex C
IPI
SpoSPBC428.13c
GO:0044427 chromosomal part C
RCA
SceS000001368
GO:0044454 nuclear chromosome part C
RCA
SceS000001368
GO:0005515 protein binding F
IPI
SpoSPBC428.13c
GO:0008047 enzyme activator activity F
RCA
SceS000001368
GO:0019207 kinase regulator activity F
IDA
SceS000001368
GO:0019209 kinase activator activity F
RCA
SceS000001368
GO:0019887 protein kinase regulator activity F
IGI
SpoSPBC428.13c
GO:0000278 mitotic cell cycle P
RCA
SceS000001368
GO:0000279 M phase P
RCA
SceS000001368
GO:0000280 nuclear division P
RCA
SceS000001368
GO:0006414 translational elongation P
RCA
SceS000001368
GO:0006468 protein amino acid phosphorylation P
IDA
SceS000001368
GO:0007096 regulation of exit from mitosis P
TAS
SceS000001368
GO:0031031 positive regulation of septation initiation
signaling		 P
IMP
SpoSPBC428.13c
GO:0034613 cellular protein localization P
IGI
SpoSPBC428.13c
GO:0045859 regulation of protein kinase activity P
IGI
SpoSPBC428.13c
GO:0048285 organelle fission P
RCA
SceS000001368
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000001368

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