Search term: YIL143C

Gene summary:

KOG results:

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG1123	ACDHYPE

KOGs classification	KOGs description
INFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING	RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, 3'-5' helicase subunit SSL2

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At5g41360	GI:9758045
Arabidopsis thaliana (Ath)	At5g41370	GI:9758046
Caenorhabditis elegans (Cel)	CE28998 (WBGene00013441)	GI:17556358	Q95PZ4
Drosophila melanogaster (Dme)	7294816	GI:7294816	B7Z0G1
Homo sapiens (Hsa)	Hs18549007	GI:18549007
Homo sapiens (Hsa)	Hs4557563 (ERCC3)	GI:4557563	P19447
Saccharomyces cerevisiae (Sce)	YIL143c (S000001405)	GI:6322048	Q00578
Schizosaccharomyces pombe (Spo)	SPAC17A5.06	GI:19114386	O13768
Encephalitozoon cuniculi (Ecu)	ECU01g1060	GI:19075117
Arabidopsis thaliana (Ath)	At5g41360	GI:9758045
Arabidopsis thaliana (Ath)	At5g41370	GI:9758046
Caenorhabditis elegans (Cel)	CE28998 (WBGene00013441)	GI:17556358	Q95PZ4
Drosophila melanogaster (Dme)	7294816	GI:7294816	B7Z0G1
Homo sapiens (Hsa)	Hs18549007	GI:18549007
Homo sapiens (Hsa)	Hs4557563 (ERCC3)	GI:4557563	P19447
Saccharomyces cerevisiae (Sce)	YIL143c (S000001405)	GI:6322048	Q00578
Schizosaccharomyces pombe (Spo)	SPAC17A5.06	GI:19114386	O13768
Encephalitozoon cuniculi (Ecu)	ECU01g1060	GI:19075117

GO terms for KOG results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000112	nucleotide-excision repair factor 3 complex	C	IDA Sce S000001405 ISS Spo SPAC17A5.06
GO:0000439	core TFIIH complex	C	IDA Sce S000001405
GO:0005634	nucleus	C	IDA Ath At5g41370 Spo SPAC17A5.06 TAS Hsa ERCC3
GO:0005654	nucleoplasm	C	EXP Hsa ERCC3
GO:0005675	holo TFIIH complex	C	IDA Hsa ERCC3 Sce S000001405 ISS Spo SPAC17A5.06 TAS Hsa ERCC3
GO:0005737	cytoplasm	C	IDA Ath At5g41370
GO:0003677	DNA binding	F	TAS Hsa ERCC3
GO:0003684	damaged DNA binding	F	NAS Hsa ERCC3
GO:0004003	ATP-dependent DNA helicase activity	F	IDA Sce S000001405 ISS Spo SPAC17A5.06
GO:0004672	protein kinase activity	F	IDA Hsa ERCC3
GO:0005515	protein binding	F	IPI Hsa ERCC3
GO:0005524	ATP binding	F	ISS Spo SPAC17A5.06
GO:0008022	protein C-terminus binding	F	IPI Hsa ERCC3
GO:0008026	ATP-dependent helicase activity	F	ISS Ath At5g41370 At5g41360
GO:0008094	DNA-dependent ATPase activity	F	IDA Hsa ERCC3 IMP Hsa ERCC3
GO:0008134	transcription factor binding	F	IDA Hsa ERCC3
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	F	IDA Hsa ERCC3
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000001405 ISS Spo SPAC17A5.06
GO:0016887	ATPase activity	F	IDA Hsa ERCC3
GO:0043138	3'-5' DNA helicase activity	F	IDA Hsa ERCC3 IMP Hsa ERCC3
GO:0047485	protein N-terminus binding	F	IPI Hsa ERCC3
GO:0000019	regulation of mitotic recombination	P	IMP Sce S000001405
GO:0000075	cell cycle checkpoint	P	IMP Hsa ERCC3
GO:0000717	nucleotide-excision repair, DNA duplex unwinding	P	IMP Hsa ERCC3
GO:0000718	nucleotide-excision repair, DNA damage removal	P	EXP Hsa ERCC3
GO:0006200	ATP catabolic process	P	ISS Spo SPAC17A5.06
GO:0006265	DNA topological change	P	IMP Hsa ERCC3
GO:0006281	DNA repair	P	IMP Hsa ERCC3
GO:0006283	transcription-coupled nucleotide-excision repair	P	IDA Hsa ERCC3 ISS Spo SPAC17A5.06
GO:0006289	nucleotide-excision repair	P	IMP Hsa ERCC3
GO:0006366	transcription from RNA polymerase II promoter	P	IDA Hsa ERCC3 IMP Hsa ERCC3
GO:0006367	transcription initiation from RNA polymerase II promoter	P	EXP Hsa ERCC3 IMP Sce S000001405 Spo SPAC17A5.06
GO:0006368	RNA elongation from RNA polymerase II promoter	P	EXP Hsa ERCC3
GO:0006917	induction of apoptosis	P	IDA Hsa ERCC3 IMP Hsa ERCC3
GO:0006979	response to oxidative stress	P	IMP Hsa ERCC3
GO:0008104	protein localization	P	IMP Hsa ERCC3
GO:0009411	response to UV	P	IEP Ath At5g41370 IMP Hsa ERCC3
GO:0009636	response to toxin	P	IMP Ath At5g41370
GO:0009792	embryo development ending in birth or egg hatching	P	IMP Cel WBGene00013441
GO:0010224	response to UV-B	P	IEP Ath At5g41360
GO:0010525	regulation of transposition, RNA-mediated	P	IMP Sce S000001405
GO:0016973	poly(A)+ mRNA export from nucleus	P	IGI Spo SPAC17A5.06 IMP Sce S000001405 Spo SPAC17A5.06
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000001405
GO:0033683	nucleotide-excision repair, DNA incision	P	IDA Sce S000001405 IMP Hsa ERCC3
GO:0034644	cellular response to UV	P	IMP Spo SPAC17A5.06
GO:0035315	hair cell differentiation	P	IMP Hsa ERCC3
GO:0045449	regulation of transcription	P	ISS Spo SPAC17A5.06
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	P	IDA Hsa ERCC3
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000001405

HomoloGene results:

HomoloGene cluster	Phylogenetic pattern
96

Species	Gene ID	NCBI link	UniProt link
Homo sapiens (Hsa)	ERCC3	GI:4557563	P19447
Pan troglodytes (Ptr)	ERCC3	GI:114580771
Canis familiaris (Cfa)	ERCC3	GI:73984146
Mus musculus (Mmu)	Ercc3 (MGI:95414)	GI:19526800	P49135
Rattus norvegicus (Rno)	Ercc3 (RGD:1307139)	GI:72255519
Gallus gallus (Gga)	ERCC3	GI:57529720
Drosophila melanogaster (Dme)	hay (FBgn0001179)	GI:24662247
Anopheles gambiae (Aga)	AgaP_AGAP012169	GI:158300446
Caenorhabditis elegans (Cel)	Y66D12A.15 (CE28998; WBGene00013441)	GI:17556358	Q95PZ4
Schizosaccharomyces pombe (Spo)	ptr8 (SPAC17A5.06)	GI:19114386	O13768
Saccharomyces cerevisiae (Sce)	SSL2 (S000001405)	GI:6322048	Q00578
Kluyveromyces lactis (Kla)	KLLA0E13057g	GI:50309063
Eremothecium gossypii (Ego)	AGOS_AFR280W	GI:45198798
Magnaporthe grisea (Mgr)	MGG_06470	GI:145608666
Neurospora crassa (Ncr)	NCU06438.1	GI:32411625
Arabidopsis thaliana (Ath)	XPB2	GI:18422089
Arabidopsis thaliana (Ath)	XPB1	GI:18422091
Oryza sativa (Osa)	Os01g0691600	GI:115439313
Plasmodium falciparum (Pfa)	PF10_0369	GI:124802985

GO terms for Homologene results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000112	nucleotide-excision repair factor 3 complex	C	IDA Sce S000001405 ISS Spo SPAC17A5.06
GO:0000439	core TFIIH complex	C	IDA Sce S000001405
GO:0000441	SSL2-core TFIIH complex	C	ISO Mmu MGI:95414
GO:0005634	nucleus	C	IC Dme FBgn0001179 IDA Ath XPB1 Spo SPAC17A5.06 NAS Dme FBgn0001179 TAS Hsa ERCC3
GO:0005654	nucleoplasm	C	EXP Hsa ERCC3
GO:0005675	holo TFIIH complex	C	IDA Hsa ERCC3 Sce S000001405 ISS Dme FBgn0001179 Spo SPAC17A5.06 TAS Hsa ERCC3
GO:0005737	cytoplasm	C	IDA Ath XPB1
GO:0020011	apicoplast	C	RCA Pfa PF10_0369
GO:0003677	DNA binding	F	TAS Hsa ERCC3
GO:0003684	damaged DNA binding	F	ISS Pfa PF10_0369 NAS Hsa ERCC3
GO:0004003	ATP-dependent DNA helicase activity	F	IDA Sce S000001405 ISO Mmu MGI:95414 ISS Spo SPAC17A5.06 NAS Dme FBgn0001179
GO:0004386	helicase activity	F	ISS Dme FBgn0001179
GO:0004672	protein kinase activity	F	IDA Hsa ERCC3
GO:0005515	protein binding	F	IPI Hsa ERCC3
GO:0005524	ATP binding	F	ISO Mmu MGI:95414 ISS Spo SPAC17A5.06
GO:0005525	GTP binding	F	ISO Mmu MGI:95414
GO:0008022	protein C-terminus binding	F	IPI Hsa ERCC3
GO:0008026	ATP-dependent helicase activity	F	ISS Ath XPB1 XPB2
GO:0008094	DNA-dependent ATPase activity	F	IDA Hsa ERCC3 IMP Hsa ERCC3
GO:0008134	transcription factor binding	F	IDA Hsa ERCC3
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	F	IDA Hsa ERCC3 ISO Mmu MGI:95414
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000001405 ISS Dme FBgn0001179 Spo SPAC17A5.06
GO:0016887	ATPase activity	F	IDA Hsa ERCC3 ISO Mmu MGI:95414
GO:0032564	dATP binding	F	ISO Mmu MGI:95414
GO:0042277	peptide binding	F	ISO Mmu MGI:95414
GO:0043138	3'-5' DNA helicase activity	F	IDA Hsa ERCC3 IMP Hsa ERCC3
GO:0047485	protein N-terminus binding	F	IPI Hsa ERCC3
GO:0000019	regulation of mitotic recombination	P	IMP Sce S000001405
GO:0000075	cell cycle checkpoint	P	IMP Hsa ERCC3
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	P	IMP Dme FBgn0001179
GO:0000717	nucleotide-excision repair, DNA duplex unwinding	P	IMP Hsa ERCC3
GO:0000718	nucleotide-excision repair, DNA damage removal	P	EXP Hsa ERCC3
GO:0006200	ATP catabolic process	P	ISO Mmu MGI:95414 ISS Spo SPAC17A5.06
GO:0006265	DNA topological change	P	IMP Hsa ERCC3
GO:0006281	DNA repair	P	IMP Hsa ERCC3
GO:0006283	transcription-coupled nucleotide-excision repair	P	IDA Hsa ERCC3 ISS Spo SPAC17A5.06
GO:0006289	nucleotide-excision repair	P	IMP Hsa ERCC3 ISS Dme FBgn0001179
GO:0006366	transcription from RNA polymerase II promoter	P	IDA Hsa ERCC3 IMP Hsa ERCC3
GO:0006367	transcription initiation from RNA polymerase II promoter	P	EXP Hsa ERCC3 IMP Sce S000001405 Spo SPAC17A5.06 ISS Dme FBgn0001179
GO:0006368	RNA elongation from RNA polymerase II promoter	P	EXP Hsa ERCC3
GO:0006468	protein amino acid phosphorylation	P	ISO Mmu MGI:95414
GO:0006917	induction of apoptosis	P	IDA Hsa ERCC3 IMP Hsa ERCC3
GO:0006979	response to oxidative stress	P	IMP Hsa ERCC3
GO:0008104	protein localization	P	IMP Hsa ERCC3
GO:0008344	adult locomotory behavior	P	IMP Dme FBgn0001179
GO:0009411	response to UV	P	IEP Ath XPB1 IMP Dme FBgn0001179 Hsa ERCC3
GO:0009636	response to toxin	P	IMP Ath XPB1
GO:0009650	UV protection	P	IGI Mmu MGI:95414
GO:0009792	embryo development ending in birth or egg hatching	P	IMP Cel WBGene00013441
GO:0010224	response to UV-B	P	IEP Ath XPB2
GO:0010525	regulation of transposition, RNA-mediated	P	IMP Sce S000001405
GO:0016973	poly(A)+ mRNA export from nucleus	P	IGI Spo SPAC17A5.06 IMP Sce S000001405 Spo SPAC17A5.06
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000001405
GO:0033683	nucleotide-excision repair, DNA incision	P	IDA Sce S000001405 IMP Hsa ERCC3
GO:0034644	cellular response to UV	P	IMP Spo SPAC17A5.06
GO:0035315	hair cell differentiation	P	IMP Hsa ERCC3
GO:0045449	regulation of transcription	P	ISS Spo SPAC17A5.06
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	P	IDA Hsa ERCC3
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000001405

OrthoMCL results:

OrthoMCL cluster	Phylogenetic pattern
OG1_1147

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Anopheles gambiae (Aga)	aga9358	ENSANGP00000013970
Ashbya gossypii (Ago)	ago3472	AFR280W
Arabidopsis thaliana (Ath)	ath25918	At5g41360.1
Arabidopsis thaliana (Ath)	ath25919	At5g41370.1
Caenorhabditis elegans (Cel)	cel20314	Y66D12A.15 (CE28998; WBGene00013441)
Candida glabrata (Cgl)	cgl4439	CAGL0L08250g
Cryptococcus neoformans (Cne)	cne2318	181.m08343
Dictyostelium discoideum (Ddi)	ddi12372	DDB0214830
Debaryomyces hansenii (Dha)	dha3672	DEHA0E09757g
Drosophila melanogaster (Dme)	dme8936	CG8019-PA (FBgn0001179)
Danio rerio (Dre)	dre20256	ENSDARP00000010637 (ercc3)	Q7ZVV1
Encephalitozoon cuniculi (Ecu)	ecu1754	19075117
Takifugu rubripes (Fru)	fru1732	SINFRUP00000133176
Gallus gallus (Gga)	gga21788	ENSGALP00000018752 (ERCC3)	Q5ZKK7
Gallus gallus (Gga)	gga21789	ENSGALP00000018753
Gallus gallus (Gga)	gga21790	ENSGALP00000018754
Homo sapiens (Hsa)	hsa18552	ENSP00000285398 (ERCC3)	P19447
Kluyveromyces lactis (Kla)	kla3536	KLLA0E13057g
Mus musculus (Mmu)	mmu12457	ENSMUSP00000025241 (MGI:95414)	P49135
Neurospora crassa (Ncr)	ncr6257	NCU06438.2
Oryza sativa (Osa)	osa13092	2914.m00190
Plasmodium falciparum (Pfa)	pfa587	PF10_0369
Rattus norvegicus (Rno)	rno13903	ENSRNOP00000018422 (RGD:1307139)	Q4G005
Saccharomyces cerevisiae (Sce)	sce3167	YIL143C (S000001405)
Schizosaccharomyces pombe (Spo)	spo2446	SPAC17A5.06	O13768
Yarrowia lipolytica (Yli)	yli1223	YALI0B11726g

GO terms for OrthoMCL results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000112	nucleotide-excision repair factor 3 complex	C	IDA Sce S000001405 ISS Spo SPAC17A5.06
GO:0000439	core TFIIH complex	C	IDA Sce S000001405
GO:0000441	SSL2-core TFIIH complex	C	ISO Mmu MGI:95414
GO:0005634	nucleus	C	IC Dme FBgn0001179 IDA Ath At5g41370 Spo SPAC17A5.06 NAS Dme FBgn0001179
GO:0005675	holo TFIIH complex	C	IDA Sce S000001405 ISS Dme FBgn0001179 Spo SPAC17A5.06
GO:0005737	cytoplasm	C	IDA Ath At5g41370
GO:0020011	apicoplast	C	RCA Pfa PF10_0369
GO:0003684	damaged DNA binding	F	ISS Pfa PF10_0369
GO:0004003	ATP-dependent DNA helicase activity	F	IDA Sce S000001405 ISO Mmu MGI:95414 ISS Spo SPAC17A5.06 NAS Dme FBgn0001179
GO:0004386	helicase activity	F	ISS Dme FBgn0001179
GO:0005524	ATP binding	F	ISO Mmu MGI:95414 ISS Spo SPAC17A5.06
GO:0005525	GTP binding	F	ISO Mmu MGI:95414
GO:0008026	ATP-dependent helicase activity	F	ISS Ath At5g41370 At5g41360
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	F	ISO Mmu MGI:95414
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000001405 ISS Dme FBgn0001179 Spo SPAC17A5.06
GO:0016887	ATPase activity	F	ISO Mmu MGI:95414
GO:0032564	dATP binding	F	ISO Mmu MGI:95414
GO:0042277	peptide binding	F	ISO Mmu MGI:95414
GO:0000019	regulation of mitotic recombination	P	IMP Sce S000001405
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	P	IMP Dme FBgn0001179
GO:0006200	ATP catabolic process	P	ISO Mmu MGI:95414 ISS Spo SPAC17A5.06
GO:0006283	transcription-coupled nucleotide-excision repair	P	ISS Spo SPAC17A5.06
GO:0006289	nucleotide-excision repair	P	ISS Dme FBgn0001179
GO:0006367	transcription initiation from RNA polymerase II promoter	P	IMP Sce S000001405 Spo SPAC17A5.06 ISS Dme FBgn0001179
GO:0006468	protein amino acid phosphorylation	P	ISO Mmu MGI:95414
GO:0008344	adult locomotory behavior	P	IMP Dme FBgn0001179
GO:0009411	response to UV	P	IEP Ath At5g41370 IMP Dme FBgn0001179
GO:0009636	response to toxin	P	IMP Ath At5g41370
GO:0009650	UV protection	P	IGI Mmu MGI:95414
GO:0009792	embryo development ending in birth or egg hatching	P	IMP Cel WBGene00013441
GO:0010224	response to UV-B	P	IEP Ath At5g41360
GO:0010525	regulation of transposition, RNA-mediated	P	IMP Sce S000001405
GO:0016973	poly(A)+ mRNA export from nucleus	P	IGI Spo SPAC17A5.06 IMP Sce S000001405 Spo SPAC17A5.06
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000001405
GO:0033683	nucleotide-excision repair, DNA incision	P	IDA Sce S000001405
GO:0034644	cellular response to UV	P	IMP Spo SPAC17A5.06
GO:0045449	regulation of transcription	P	ISS Spo SPAC17A5.06
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000001405

Curated yeast ortholog results:

S. pombe systematic ID	S. cerevisiae systematic ID
SPAC17A5.06 (O13768)	YIL143C (S000001405)

GO terms for curated homolog results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000112	nucleotide-excision repair factor 3 complex	C	IDA Sce S000001405 ISS Spo SPAC17A5.06
GO:0000439	core TFIIH complex	C	IDA Sce S000001405
GO:0005634	nucleus	C	IDA Spo SPAC17A5.06
GO:0005675	holo TFIIH complex	C	IDA Sce S000001405 ISS Spo SPAC17A5.06
GO:0004003	ATP-dependent DNA helicase activity	F	IDA Sce S000001405 ISS Spo SPAC17A5.06
GO:0005524	ATP binding	F	ISS Spo SPAC17A5.06
GO:0016251	general RNA polymerase II transcription factor activity	F	IDA Sce S000001405 ISS Spo SPAC17A5.06
GO:0000019	regulation of mitotic recombination	P	IMP Sce S000001405
GO:0006200	ATP catabolic process	P	ISS Spo SPAC17A5.06
GO:0006283	transcription-coupled nucleotide-excision repair	P	ISS Spo SPAC17A5.06
GO:0006367	transcription initiation from RNA polymerase II promoter	P	IMP Sce S000001405 Spo SPAC17A5.06
GO:0010525	regulation of transposition, RNA-mediated	P	IMP Sce S000001405
GO:0016973	poly(A)+ mRNA export from nucleus	P	IGI Spo SPAC17A5.06 IMP Sce S000001405 Spo SPAC17A5.06
GO:0032568	general transcription from RNA polymerase II promoter	P	IDA Sce S000001405
GO:0033683	nucleotide-excision repair, DNA incision	P	IDA Sce S000001405
GO:0034644	cellular response to UV	P	IMP Spo SPAC17A5.06
GO:0045449	regulation of transcription	P	ISS Spo SPAC17A5.06
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	P	IDA Sce S000001405