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Search term: YIL144W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TID3
SGD link S000001406
Alternative ID YIL144W
Description Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, kinetochore assembly and clustering
Synonyms YIL144W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0995 AC-HYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Centromere-associated protein HEC1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g54630 GI:15232555
Caenorhabditis elegans (Cel) CE06537
(WBGene00003576)		 GI:17542728 Q17635
Homo sapiens (Hsa) Hs5174457
(NDC80)		 GI:5174457 O14777
Saccharomyces cerevisiae (Sce) YIL144w
(S000001406)		 GI:6322047 P40460
Schizosaccharomyces pombe (Spo) SPBC11C11.03 GI:19113184 Q10198
Encephalitozoon cuniculi (Ecu) ECU10g0810 GI:19074690 Q8SUE9
Arabidopsis thaliana (Ath) At3g54630 GI:15232555
Caenorhabditis elegans (Cel) CE06537
(WBGene00003576)		 GI:17542728 Q17635
Homo sapiens (Hsa) Hs5174457
(NDC80)		 GI:5174457 O14777
Saccharomyces cerevisiae (Sce) YIL144w
(S000001406)		 GI:6322047 P40460
Schizosaccharomyces pombe (Spo) SPBC11C11.03 GI:19113184 Q10198
Encephalitozoon cuniculi (Ecu) ECU10g0810 GI:19074690 Q8SUE9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000775 chromosome, centromeric region C
TAS
HsaNDC80
GO:0000776 kinetochore C
IDA
HsaNDC80
GO:0000777 condensed chromosome kinetochore C
IDA
HsaNDC80
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000001406
SpoSPBC11C11.03
IMP
SceS000001406
IPI
SceS000001406
GO:0000780 condensed nuclear chromosome, centromeric
region		 C
IDA
SceS000001406
IGI
SceS000001406
IPI
SceS000001406
GO:0000922 spindle pole C
RCA
SceS000001406
GO:0000942 outer kinetochore of condensed nuclear
chromosome		 C
IDA
HsaNDC80
GO:0005575 cellular_component C
ND
AthAt3g54630
GO:0005816 spindle pole body C
IDA
SpoSPBC11C11.03
GO:0005819 spindle C
RCA
SceS000001406
GO:0005856 cytoskeleton C
RCA
SceS000001406
GO:0015630 microtubule cytoskeleton C
RCA
SceS000001406
GO:0031262 Ndc80 complex C
IDA
HsaNDC80
SceS000001406
IPI
SceS000001406
TAS
SpoSPBC11C11.03
GO:0031617 NMS complex C
IDA
SpoSPBC11C11.03
GO:0044430 cytoskeletal part C
RCA
SceS000001406
GO:0003674 molecular_function F
ND
AthAt3g54630
GO:0005200 structural constituent of cytoskeleton F
IPI
SceS000001406
GO:0005515 protein binding F
IPI
HsaNDC80
SpoSPBC11C11.03
GO:0000003 reproduction P
IMP
CelWBGene00003576
GO:0000070 mitotic sister chromatid segregation P
TAS
HsaNDC80
GO:0000132 establishment of mitotic spindle
orientation		 P
IMP
HsaNDC80
GO:0000278 mitotic cell cycle P
RCA
SceS000001406
GO:0000279 M phase P
RCA
SceS000001406
GO:0000910 cytokinesis P
IMP
CelWBGene00003576
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00003576
GO:0007020 microtubule nucleation P
IPI
SceS000001406
GO:0007049 cell cycle P
NAS
HsaNDC80
GO:0007051 spindle organization P
NAS
HsaNDC80
GO:0007052 mitotic spindle organization P
IMP
HsaNDC80
GO:0007059 chromosome segregation P
IC
SpoSPBC11C11.03
IGI
SceS000001406
IMP
HsaNDC80
SceS000001406
GO:0007067 mitosis P
TAS
HsaNDC80
GO:0008150 biological_process P
ND
AthAt3g54630
GO:0008608 attachment of spindle microtubules to
kinetochore		 P
IDA
SpoSPBC11C11.03
IMP
HsaNDC80
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003576
GO:0019236 response to pheromone P
IMP
SpoSPBC11C11.03
GO:0030334 regulation of cell migration P
IMP
CelWBGene00003576
GO:0034501 protein localization to kinetochore P
IMP
SceS000001406
GO:0035262 gonad morphogenesis P
IMP
CelWBGene00003576
GO:0040011 locomotion P
IMP
CelWBGene00003576
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003576
GO:0040039 inductive cell migration P
IMP
CelWBGene00003576
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaNDC80
GO:0051301 cell division P
IMP
CelWBGene00003576
GO:0051455 attachment of spindle microtubules to kinetochore
involved in homologous chromosome
segregation		 P
IDA
SpoSPBC11C11.03

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38141

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) NDC80 GI:5174457 O14777
Pan troglodytes (Ptr) NDC80 GI:114672431
Canis familiaris (Cfa) NDC80 GI:73962052
Mus musculus (Mmu) Ndc80
(MGI:1914302)		 GI:12963625 Q9D0F1
Rattus norvegicus (Rno) Ndc80 GI:109486461
Gallus gallus (Gga) NDC80 GI:54020712
Caenorhabditis elegans (Cel) ndc-80
(CE06537;
WBGene00003576)		 GI:17542728 Q17635
Schizosaccharomyces pombe (Spo) ndc10 GI:19113184
Saccharomyces cerevisiae (Sce) TID3
(S000001406)		 GI:6322047 P40460
Kluyveromyces lactis (Kla) KLLA0E13035g GI:50309061
Eremothecium gossypii (Ego) AGOS_AFR281C GI:45198799
Magnaporthe grisea (Mgr) MGG_01027 GI:39973653
Neurospora crassa (Ncr) NCU03899.1 GI:32405210
Arabidopsis thaliana (Ath) AT3G54630 GI:15232555
Oryza sativa (Osa) Os08g0468400 GI:115476824


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000775 chromosome, centromeric region C
ISO
MmuMGI:1914302
TAS
HsaNDC80
GO:0000776 kinetochore C
IDA
HsaNDC80
GO:0000777 condensed chromosome kinetochore C
IDA
HsaNDC80
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000001406
IMP
SceS000001406
IPI
SceS000001406
GO:0000780 condensed nuclear chromosome, centromeric
region		 C
IDA
SceS000001406
IGI
SceS000001406
IPI
SceS000001406
GO:0000922 spindle pole C
RCA
SceS000001406
GO:0000942 outer kinetochore of condensed nuclear
chromosome		 C
IDA
HsaNDC80
GO:0005575 cellular_component C
ND
AthAt3g54630
GO:0005634 nucleus C
ISO
MmuMGI:1914302
GO:0005819 spindle C
RCA
SceS000001406
GO:0005856 cytoskeleton C
RCA
SceS000001406
GO:0015630 microtubule cytoskeleton C
RCA
SceS000001406
GO:0031262 Ndc80 complex C
IDA
HsaNDC80
SceS000001406
IPI
SceS000001406
GO:0044430 cytoskeletal part C
RCA
SceS000001406
GO:0003674 molecular_function F
ND
AthAt3g54630
GO:0005200 structural constituent of cytoskeleton F
IPI
SceS000001406
GO:0005515 protein binding F
IPI
HsaNDC80
MmuMGI:1914302
GO:0000003 reproduction P
IMP
CelWBGene00003576
GO:0000070 mitotic sister chromatid segregation P
TAS
HsaNDC80
GO:0000089 mitotic metaphase P
ISO
MmuMGI:1914302
GO:0000132 establishment of mitotic spindle
orientation		 P
IMP
HsaNDC80
GO:0000278 mitotic cell cycle P
RCA
SceS000001406
GO:0000279 M phase P
RCA
SceS000001406
GO:0000910 cytokinesis P
IMP
CelWBGene00003576
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00003576
GO:0007020 microtubule nucleation P
IPI
SceS000001406
GO:0007049 cell cycle P
NAS
HsaNDC80
GO:0007051 spindle organization P
NAS
HsaNDC80
GO:0007052 mitotic spindle organization P
IMP
HsaNDC80
GO:0007059 chromosome segregation P
IGI
SceS000001406
IMP
HsaNDC80
SceS000001406
GO:0007067 mitosis P
TAS
HsaNDC80
GO:0008150 biological_process P
ND
AthAt3g54630
GO:0008608 attachment of spindle microtubules to
kinetochore		 P
IMP
HsaNDC80
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003576
GO:0030334 regulation of cell migration P
IMP
CelWBGene00003576
GO:0034501 protein localization to kinetochore P
IMP
SceS000001406
GO:0035262 gonad morphogenesis P
IMP
CelWBGene00003576
GO:0040011 locomotion P
IMP
CelWBGene00003576
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003576
GO:0040039 inductive cell migration P
IMP
CelWBGene00003576
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaNDC80
GO:0051301 cell division P
IMP
CelWBGene00003576

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2486

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3473 AFR281C
Arabidopsis thaliana (Ath) ath16830 At3g54630.1
Caenorhabditis elegans (Cel) cel16738 W01B6.9
(CE06537;
WBGene00003576)
Candida glabrata (Cgl) cgl777 CAGL0D02684g
Cryptococcus neoformans (Cne) cne3097 167.m03404
Dictyostelium discoideum (Ddi) ddi9814 DDB0218558
Debaryomyces hansenii (Dha) dha3686 DEHA0E10065g
Drosophila melanogaster (Dme) dme17723 CG9938-PA
(FBgn0030500)
Danio rerio (Dre) dre3221 ENSDARP00000012236
(kntc2l)		 Q6DRJ7-1
Encephalitozoon cuniculi (Ecu) ecu606 19074690
Takifugu rubripes (Fru) fru9342 SINFRUP00000132722
Gallus gallus (Gga) gga10966 ENSGALP00000023851
(NDC80)		 Q76I89
Homo sapiens (Hsa) hsa14668 ENSP00000261597
(NDC80)		 O14777
Kluyveromyces lactis (Kla) kla3535 KLLA0E13035g
Mus musculus (Mmu) mmu12079 ENSMUSP00000024851
(MGI:1914302)		 Q9D0F1
Neurospora crassa (Ncr) ncr3788 NCU03899.2
Oryza sativa (Osa) osa26554 3939.m00193
Oryza sativa (Osa) osa37461 4982.m00154
Plasmodium falciparum (Pfa) pfa3122 PFF0785w
Rattus norvegicus (Rno) rno30635 ENSRNOP00000018644
(RGD:1310154)		 B1WBY4
Saccharomyces cerevisiae (Sce) sce3168 YIL144W
(S000001406)
Schizosaccharomyces pombe (Spo) spo3779 SPBC11C11.03 Q10198
Yarrowia lipolytica (Yli) yli1227 YALI0B11814g