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Search term: YIL153W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RRD1
SGD link S000001415
Alternative ID YIL153W
Description Peptidyl-prolyl cis/trans-isomerase, activator of the phosphotyrosyl phosphatase activity of PP2A; involved in G1 phase progression, microtubule dynamics, bud morphogenesis and DNA repair; subunit of the Tap42p-Sit4p-Rrd1p complex
Synonyms YIL153W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2867 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Phosphotyrosyl phosphatase activator

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g08960 GI:4325370
Caenorhabditis elegans (Cel) CE27321
(WBGene00022185)
GI:17556450 Q9BL35
Drosophila melanogaster (Dme) 7293136
(FBgn0030696)
GI:18859943
Drosophila melanogaster (Dme) 7295814 GI:7295814
Drosophila melanogaster (Dme) 7296690 GI:7296690 Q9VNG7
Homo sapiens (Hsa) Hs10880987 GI:10880987
Homo sapiens (Hsa) Hs22046124 GI:22046124
Saccharomyces cerevisiae (Sce) YIL153w
(S000001415)
GI:6322038 P40454
Saccharomyces cerevisiae (Sce) YPL152w
(S000006073)
GI:6325105 Q12461
Schizosaccharomyces pombe (Spo) SPAC1782.05 GI:19115624 Q9P7H4
Schizosaccharomyces pombe (Spo) SPAC4F10.04 GI:19115659 O36016
Encephalitozoon cuniculi (Ecu) ECU06g0720 GI:19074322 Q8SVB5


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000159 protein phosphatase type 2A complex C
IDA
SceS000006073
GO:0000267 cell fraction C
IDA
SceS000006073
S000001415
GO:0005575 cellular_component C
ND
AthAt4g08960
GO:0005634 nucleus C
IDA
SceS000001415
SpoSPAC4F10.04
ISS
SpoSPAC4F10.04
GO:0005737 cytoplasm C
IDA
SceS000001415
SpoSPAC1782.05
ISS
SpoSPAC4F10.04
GO:0005829 cytosol C
IDA
SpoSPAC4F10.04
TAS
SceS000006073
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
IDA
SceS000006073
S000001415
GO:0008160 protein tyrosine phosphatase activator
activity
F
ISS
DmeFBgn0030696
GO:0008601 protein phosphatase type 2A regulator
activity
F
IGI
SceS000001415
S000006073
IMP
SceS000001415
S000006073
ISA
SceS000001415
ISS
SceS000001415
S000006073
SpoSPAC4F10.04
SPAC1782.05
GO:0019211 phosphatase activator activity F
ISS
AthAt4g08960
GO:0000003 reproduction P
IMP
CelWBGene00022185
GO:0000082 G1/S transition of mitotic cell
cycle
P
IPI
SceS000001415
GO:0002119 nematode larval development P
IMP
CelWBGene00022185
GO:0006281 DNA repair P
IMP
SceS000001415
GO:0006282 regulation of DNA repair P
ISS
SpoSPAC4F10.04
GO:0006970 response to osmotic stress P
IGI
SceS000001415
S000006073
IMP
SceS000006073
S000001415
GO:0007052 mitotic spindle organization P
ISS
SpoSPAC1782.05
GO:0007165 signal transduction P
NAS
SpoSPAC4F10.04
GO:0008150 biological_process P
ND
AthAt4g08960
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00022185
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00022185
GO:0030472 mitotic spindle organization in
nucleus
P
IMP
SceS000006073
S000001415
GO:0040007 growth P
IMP
CelWBGene00022185
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00022185
GO:0060236 regulation of mitotic spindle organization P
ISS
SpoSPAC4F10.04

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6149

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PPP2R4 GI:30065643
Pan troglodytes (Ptr) PPP2R4 GI:114627097
Canis familiaris (Cfa) PPP2R4 GI:73968031
Mus musculus (Mmu) Ppp2r4
(MGI:1346006)
GI:31981677 P58389
Rattus norvegicus (Rno) Ppp2r4 GI:109467991
Gallus gallus (Gga) PPP2R4 GI:71897339
Drosophila melanogaster (Dme) Ptpa
(FBgn0016698)
GI:24581421
Anopheles gambiae (Aga) AgaP_AGAP008652 GI:158293406
Caenorhabditis elegans (Cel) Y71H2AM.20
(CE27321;
WBGene00022185)
GI:17556450 Q9BL35
Schizosaccharomyces pombe (Spo) SPAC4F10.04 GI:19115659 O36016
Saccharomyces cerevisiae (Sce) RRD1
(S000001415)
GI:6322038 P40454
Kluyveromyces lactis (Kla) KLLA0A00462g GI:50302169
Eremothecium gossypii (Ego) AGOS_AFR293C GI:45198811
Magnaporthe grisea (Mgr) MGG_04320 GI:39944618
Neurospora crassa (Ncr) NCU04810.1 GI:32407149
Arabidopsis thaliana (Ath) AT4G08960 GI:18413175
Oryza sativa (Osa) Os06g0219800 GI:115467132
Plasmodium falciparum (Pfa) PF14_0280 GI:124808967


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000159 protein phosphatase type 2A complex C
TAS
HsaPPP2R4
GO:0000267 cell fraction C
IDA
SceS000001415
GO:0005575 cellular_component C
ND
AthAt4g08960
PfaPF14_0280
GO:0005625 soluble fraction C
TAS
HsaPPP2R4
GO:0005634 nucleus C
IDA
HsaPPP2R4
SceS000001415
SpoSPAC4F10.04
ISS
SpoSPAC4F10.04
GO:0005737 cytoplasm C
IDA
HsaPPP2R4
SceS000001415
ISS
SpoSPAC4F10.04
GO:0005829 cytosol C
IDA
SpoSPAC4F10.04
GO:0034704 calcium channel complex C
IDA
HsaPPP2R4
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
IDA
SceS000001415
GO:0005102 receptor binding F
IPI
HsaPPP2R4
GO:0005524 ATP binding F
IDA
HsaPPP2R4
GO:0008160 protein tyrosine phosphatase activator
activity
F
IDA
HsaPPP2R4
ISS
DmeFBgn0016698
PfaPF14_0280
NAS
DmeFBgn0016698
GO:0008601 protein phosphatase type 2A regulator
activity
F
IDA
HsaPPP2R4
IGI
SceS000001415
IMP
SceS000001415
ISA
SceS000001415
ISS
SceS000001415
SpoSPAC4F10.04
TAS
HsaPPP2R4
GO:0016887 ATPase activity F
IDA
HsaPPP2R4
GO:0019211 phosphatase activator activity F
ISS
AthAt4g08960
GO:0042803 protein homodimerization activity F
IDA
HsaPPP2R4
GO:0046982 protein heterodimerization activity F
TAS
HsaPPP2R4
GO:0051721 protein phosphatase 2A binding F
IDA
HsaPPP2R4
GO:0000003 reproduction P
IMP
CelWBGene00022185
GO:0000082 G1/S transition of mitotic cell
cycle
P
IPI
SceS000001415
GO:0002119 nematode larval development P
IMP
CelWBGene00022185
GO:0006281 DNA repair P
IMP
SceS000001415
GO:0006282 regulation of DNA repair P
ISS
SpoSPAC4F10.04
GO:0006470 protein amino acid dephosphorylation P
ISS
PfaPF14_0280
GO:0006970 response to osmotic stress P
IGI
SceS000001415
IMP
SceS000001415
GO:0007165 signal transduction P
NAS
SpoSPAC4F10.04
GO:0008150 biological_process P
ND
AthAt4g08960
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00022185
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00022185
GO:0030472 mitotic spindle organization in
nucleus
P
IMP
SceS000001415
GO:0032515 negative regulation of phosphoprotein phosphatase
activity
P
IDA
HsaPPP2R4
GO:0032516 positive regulation of phosphoprotein phosphatase
activity
P
IDA
HsaPPP2R4
GO:0035307 positive regulation of protein amino acid
dephosphorylation
P
IDA
HsaPPP2R4
GO:0035308 negative regulation of protein amino acid
dephosphorylation
P
IDA
HsaPPP2R4
GO:0040007 growth P
IMP
CelWBGene00022185
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00022185
GO:0043065 positive regulation of apoptosis P
IDA
HsaPPP2R4
GO:0043666 regulation of phosphoprotein phosphatase
activity
P
IDA
HsaPPP2R4
GO:0050790 regulation of catalytic activity P
NAS
DmeFBgn0016698
GO:0060236 regulation of mitotic spindle organization P
ISS
SpoSPAC4F10.04

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_965

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga10672 ENSANGP00000013063
Ashbya gossypii (Ago) ago1186 ACR139C
Ashbya gossypii (Ago) ago3485 AFR293C
Arabidopsis thaliana (Ath) ath18624 At4g08960.1
Caenorhabditis elegans (Cel) cel20640 Y71H2AM.20a
(CE27321;
WBGene00022185)
Candida glabrata (Cgl) cgl2352 CAGL0H06655g
Candida glabrata (Cgl) cgl4754 CAGL0M02255g
Cryptococcus neoformans (Cne) cne3491 176.m02505
Dictyostelium discoideum (Ddi) ddi1753 DDB0190756
Dictyostelium discoideum (Ddi) ddi5781 DDB0205963
Debaryomyces hansenii (Dha) dha2027 DEHA0C13541g
Debaryomyces hansenii (Dha) dha4102 DEHA0E19448g
Drosophila melanogaster (Dme) dme578 CG3289-PA
(FBgn0016698)
Danio rerio (Dre) dre15748 ENSDARP00000039540
Danio rerio (Dre) dre15749 ENSDARP00000050040
(zgc:92766)
Q6DGU6
Encephalitozoon cuniculi (Ecu) ecu1549 19074322
Takifugu rubripes (Fru) fru12786 SINFRUP00000141841
Takifugu rubripes (Fru) fru12787 SINFRUP00000141842
Gallus gallus (Gga) gga26915 ENSGALP00000022611
(PPP2R4)
Q5ZM56
Homo sapiens (Hsa) hsa32032 ENSP00000266101
Homo sapiens (Hsa) hsa32035 ENSP00000335200
(PPP2R4)
A6PVN5
Homo sapiens (Hsa) hsa32033 ENSP00000337412
(PPP2R4)
Q68CR8
Homo sapiens (Hsa) hsa32036 ENSP00000337448
(PPP2R4)
Q15257-1
Homo sapiens (Hsa) hsa32031 ENSP00000347109
(PPP2R4)
Q15257-4
Homo sapiens (Hsa) hsa32034 ENSP00000349726
(PPP2R4)
Q15257-3
Homo sapiens (Hsa) hsa32030 ENSP00000351885
(PPP2R4)
Q15257-2
Kluyveromyces lactis (Kla) kla15 KLLA0A00462g
Kluyveromyces lactis (Kla) kla4589 KLLA0F11187g
Mus musculus (Mmu) mmu14376 ENSMUSP00000046837
(MGI:1346006)
P58389
Neurospora crassa (Ncr) ncr3167 NCU03269.2
Neurospora crassa (Ncr) ncr4671 NCU04810.2
Oryza sativa (Osa) osa1978 1899.m00175
Plasmodium falciparum (Pfa) pfa1731 PF14_0280
Rattus norvegicus (Rno) rno18363 ENSRNOP00000024914
(RGD:1308354)
B2RYQ2
Saccharomyces cerevisiae (Sce) sce3177 YIL153W
(S000001415)
Saccharomyces cerevisiae (Sce) sce6311 YPL152W
(S000006073)
Schizosaccharomyces pombe (Spo) spo1032 SPAC1782.05 Q9P7H4
Schizosaccharomyces pombe (Spo) spo2914 SPAC4F10.04 O36016
Yarrowia lipolytica (Yli) yli857 YALI0B02772g
Yarrowia lipolytica (Yli) yli4054 YALI0E04642g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000159 protein phosphatase type 2A complex C
IDA
SceS000006073
GO:0000267 cell fraction C
IDA
SceS000006073
S000001415
GO:0005575 cellular_component C
ND
AthAt4g08960
PfaPF14_0280
GO:0005634 nucleus C
IDA
SceS000001415
SpoSPAC4F10.04
ISS
SpoSPAC4F10.04
GO:0005737 cytoplasm C
IDA
SceS000001415
SpoSPAC1782.05
ISS
SpoSPAC4F10.04
GO:0005829 cytosol C
IDA
SpoSPAC4F10.04
TAS
SceS000006073
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
IDA
SceS000006073
S000001415
GO:0008160 protein tyrosine phosphatase activator
activity
F
ISS
DmeFBgn0016698
PfaPF14_0280
NAS
DmeFBgn0016698
GO:0008601 protein phosphatase type 2A regulator
activity
F
IGI
SceS000001415
S000006073
IMP
SceS000001415
S000006073
ISA
SceS000001415
ISS
SceS000001415
S000006073
SpoSPAC4F10.04
SPAC1782.05
GO:0019211 phosphatase activator activity F
ISS
AthAt4g08960
GO:0000003 reproduction P
IMP
CelWBGene00022185
GO:0000082 G1/S transition of mitotic cell
cycle
P
IPI
SceS000001415
GO:0002119 nematode larval development P
IMP
CelWBGene00022185
GO:0006281 DNA repair P
IMP
SceS000001415
GO:0006282 regulation of DNA repair P
ISS
SpoSPAC4F10.04
GO:0006470 protein amino acid dephosphorylation P
ISS
PfaPF14_0280
GO:0006970 response to osmotic stress P
IGI
SceS000001415
S000006073
IMP
SceS000006073
S000001415
GO:0007052 mitotic spindle organization P
ISS
SpoSPAC1782.05
GO:0007165 signal transduction P
NAS
SpoSPAC4F10.04
GO:0008150 biological_process P
ND
AthAt4g08960
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00022185
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00022185
GO:0030472 mitotic spindle organization in
nucleus
P
IMP
SceS000006073
S000001415
GO:0040007 growth P
IMP
CelWBGene00022185
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00022185
GO:0050790 regulation of catalytic activity P
NAS
DmeFBgn0016698
GO:0060236 regulation of mitotic spindle organization P
ISS
SpoSPAC4F10.04

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC4F10.04
(O36016)
YIL153W
(S000001415)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000267 cell fraction C
IDA
SceS000001415
GO:0005634 nucleus C
IDA
SceS000001415
SpoSPAC4F10.04
ISS
SpoSPAC4F10.04
GO:0005737 cytoplasm C
IDA
SceS000001415
ISS
SpoSPAC4F10.04
GO:0005829 cytosol C
IDA
SpoSPAC4F10.04
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
IDA
SceS000001415
GO:0008601 protein phosphatase type 2A regulator
activity
F
IGI
SceS000001415
IMP
SceS000001415
ISA
SceS000001415
ISS
SceS000001415
SpoSPAC4F10.04
GO:0000082 G1/S transition of mitotic cell
cycle
P
IPI
SceS000001415
GO:0006281 DNA repair P
IMP
SceS000001415
GO:0006282 regulation of DNA repair P
ISS
SpoSPAC4F10.04
GO:0006970 response to osmotic stress P
IGI
SceS000001415
IMP
SceS000001415
GO:0007165 signal transduction P
NAS
SpoSPAC4F10.04
GO:0030472 mitotic spindle organization in
nucleus
P
IMP
SceS000001415
GO:0060236 regulation of mitotic spindle organization P
ISS
SpoSPAC4F10.04

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