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Search term: YIR019C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MUC1
SGD link S000001458
Alternative ID YIR019C
Description GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)
Synonyms YIR019C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68255

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MUC17 GI:91982772
Pan troglodytes (Ptr) MUC17 GI:114615083
Schizosaccharomyces pombe (Spo) SPBPJ4664.02 GI:19112069 Q96WV6
Saccharomyces cerevisiae (Sce) MUC1
(S000001458)		 GI:6322209
Kluyveromyces lactis (Kla) KLLA0E01001g GI:50307991


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
HsaMUC17
GO:0005886 plasma membrane C
IDA
SceS000001458
GO:0005935 cellular bud neck C
IDA
SceS000001458
GO:0010339 external side of cell wall C
NAS
SpoSPBPJ4664.02
GO:0003674 molecular_function F
ND
SceS000001458
GO:0030197 extracellular matrix constituent, lubricant
activity		 F
NAS
HsaMUC17
GO:0000128 flocculation P
IMP
SceS000001458
GO:0001403 invasive growth in response to glucose
limitation		 P
IMP
SceS000001458
GO:0007124 pseudohyphal growth P
IMP
SceS000001458
GO:0007155 cell adhesion P
NAS
SpoSPBPJ4664.02
GO:0008150 biological_process P
ND
HsaMUC17
GO:0030447 filamentous growth P
IDA
SceS000001458
GO:0042710 biofilm formation P
IMP
SceS000001458

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_317

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga11779 ENSANGP00000020885
Ashbya gossypii (Ago) ago1941 ADR200C
Ashbya gossypii (Ago) ago2483 AEL023C
Caenorhabditis elegans (Cel) cel11997 K06A9.1a
(CE19524;
WBGene00019435)
Caenorhabditis elegans (Cel) cel11998 K06A9.1b
(CE19525)
Caenorhabditis elegans (Cel) cel11999 K06A9.1c
(CE34576)
Caenorhabditis elegans (Cel) cel19491 Y51B11A.1
(CE22326;
WBGene00021761)
Caenorhabditis elegans (Cel) cel21180 ZC178.2
(CE15064;
WBGene00022536)
Candida glabrata (Cgl) cgl572 CAGL0C03575g
Candida glabrata (Cgl) cgl1358 CAGL0F03003g
Cryptococcus neoformans (Cne) cne302 162.m02849
Cryptococcus neoformans (Cne) cne487 163.m06325
Dictyostelium discoideum (Ddi) ddi7222 DDB0188170
Dictyostelium discoideum (Ddi) ddi4718 DDB0204217
Dictyostelium discoideum (Ddi) ddi4441 DDB0204485
Dictyostelium discoideum (Ddi) ddi9459 DDB0215928
Debaryomyces hansenii (Dha) dha5768 DEHA0G01573g
Debaryomyces hansenii (Dha) dha5769 DEHA0G01595g
Drosophila melanogaster (Dme) dme9090 CG18331-PA
(FBgn0036181)
Drosophila melanogaster (Dme) dme18107 CG32580-PA
(FBgn0052580)
Danio rerio (Dre) dre19797 ENSDARP00000005210
Danio rerio (Dre) dre19798 ENSDARP00000007706
Danio rerio (Dre) dre13307 ENSDARP00000018951
Danio rerio (Dre) dre21347 ENSDARP00000025607
Danio rerio (Dre) dre1045 ENSDARP00000032692
Danio rerio (Dre) dre24510 ENSDARP00000035858
Danio rerio (Dre) dre1044 ENSDARP00000037937
Danio rerio (Dre) dre21282 ENSDARP00000049156
Danio rerio (Dre) dre16016 ENSDARP00000049852
Takifugu rubripes (Fru) fru19415 SINFRUP00000147574
Takifugu rubripes (Fru) fru21473 SINFRUP00000171200
Takifugu rubripes (Fru) fru3084 SINFRUP00000172170
Gallus gallus (Gga) gga14076 ENSGALP00000002153
(MUC16)
Gallus gallus (Gga) gga18931 ENSGALP00000010889
Homo sapiens (Hsa) hsa15543 ENSP00000333016
(MUC16)		 A8MQ24
Kluyveromyces lactis (Kla) kla2347 KLLA0D06446g
Kluyveromyces lactis (Kla) kla2994 KLLA0E01001g
Kluyveromyces lactis (Kla) kla4151 KLLA0F01595g
Mus musculus (Mmu) mmu10223 ENSMUSP00000051343
Mus musculus (Mmu) mmu10224 ENSMUSP00000063720
Mus musculus (Mmu) mmu10225 ENSMUSP00000070908
Mus musculus (Mmu) mmu10221 ENSMUSP00000071781
Mus musculus (Mmu) mmu27078 ENSMUSP00000074780
Mus musculus (Mmu) mmu10222 ENSMUSP00000080671
Neurospora crassa (Ncr) ncr5936 NCU06109.2
Neurospora crassa (Ncr) ncr6072 NCU06247.2
Neurospora crassa (Ncr) ncr7083 NCU07277.2
Rattus norvegicus (Rno) rno3298 ENSRNOP00000026749
(RGD:628826)		 Q8CJD9
Rattus norvegicus (Rno) rno28016 ENSRNOP00000035004
Saccharomyces cerevisiae (Sce) sce746 YCR089W
(S000000685)
Saccharomyces cerevisiae (Sce) sce1486 YDR420W
(S000002828)
Saccharomyces cerevisiae (Sce) sce3226 YIR019C
(S000001458)
Schizosaccharomyces pombe (Spo) spo371 SPBPJ4664.02 Q96WV6
Yarrowia lipolytica (Yli) yli1886 YALI0C04136g
Yarrowia lipolytica (Yli) yli2802 YALI0D02299g
Yarrowia lipolytica (Yli) yli4791 YALI0E22572g
Yarrowia lipolytica (Yli) yli6462 YALI0F26763g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005886 plasma membrane C
IDA
SceS000001458
S000002828
ISS
SceS000002828
GO:0005935 cellular bud neck C
IDA
SceS000001458
GO:0005937 mating projection C
IDA
SceS000000685
GO:0009277 fungal-type cell wall C
IDA
SceS000000685
GO:0010339 external side of cell wall C
NAS
SpoSPBPJ4664.02
GO:0030427 site of polarized growth C
IDA
SceS000002828
GO:0003674 molecular_function F
ND
SceS000001458
S000000685
GO:0005034 osmosensor activity F
IGI
SceS000002828
GO:0000128 flocculation P
IMP
SceS000001458
GO:0000282 cellular bud site selection P
IMP
SceS000002828
GO:0000753 cell morphogenesis involved in conjugation with
cellular fusion		 P
IMP
SceS000000685
GO:0000755 cytogamy P
IMP
SceS000000685
GO:0001403 invasive growth in response to glucose
limitation		 P
IMP
SceS000001458
GO:0006075 1,3-beta-glucan biosynthetic process P
IMP
SceS000002828
GO:0006414 translational elongation P
RCA
SceS000000685
GO:0006972 hyperosmotic response P
IGI
SceS000002828
GO:0007124 pseudohyphal growth P
IMP
SceS000001458
GO:0007155 cell adhesion P
NAS
SpoSPBPJ4664.02
GO:0007232 osmosensory signaling pathway via Sho1
osmosensor		 P
IGI
SceS000002828
IPI
SceS000002828
GO:0030447 filamentous growth P
IDA
SceS000001458
GO:0031505 fungal-type cell wall organization P
IMP
SceS000002828
GO:0042710 biofilm formation P
IMP
SceS000001458

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s.khadayate@ucl.ac.uk