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Search term: YIR022W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SEC11
SGD link S000001461
Alternative ID YIR022W
Description 18kDa catalytic subunit of the Signal Peptidase Complex (SPC; Spc1p, Spc2p, Spc3p, and Sec11p) which cleaves the signal sequence of proteins targeted to the endoplasmic reticulum
Synonyms YIR022W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3342 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Signal peptidase I

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g52600 GI:15219044
Arabidopsis thaliana (Ath) At3g15710 GI:15232668
Caenorhabditis elegans (Cel) CE22466
(WBGene00021844)
GI:17510347 Q9N3D0
Drosophila melanogaster (Dme) 7298894 GI:4389443
Homo sapiens (Hsa) Hs18570823 GI:18570823
Homo sapiens (Hsa) Hs15150809
(SEC11C)
GI:15150809 Q9BY50
Homo sapiens (Hsa) Hs7657609
(SEC11A)
GI:7657609 P67812
Saccharomyces cerevisiae (Sce) YIR022w
(S000001461)
GI:6322213 P15367
Schizosaccharomyces pombe (Spo) SPBC1685.03 GI:19111999 O74323
Encephalitozoon cuniculi (Ecu) ECU02g0760 GI:19073996 Q8SSG0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
AthAt3g15710
At1g52600
SceS000001461
SpoSPBC1685.03
GO:0005787 signal peptidase complex C
IDA
SceS000001461
ISS
SpoSPBC1685.03
GO:0005886 plasma membrane C
IDA
AthAt3g15710
At1g52600
GO:0016020 membrane C
ISS
AthAt3g15710
At1g52600
GO:0005515 protein binding F
IPI
HsaSEC11A
GO:0008233 peptidase activity F
IMP
SceS000001461
ISS
AthAt3g15710
At1g52600
SceS000001461
SpoSPBC1685.03
GO:0000003 reproduction P
IMP
CelWBGene00021844
GO:0002119 nematode larval development P
IMP
CelWBGene00021844
GO:0006465 signal peptide processing P
IDA
SceS000001461
IMP
SceS000001461
IPI
SceS000001461
ISS
SceS000001461
SpoSPBC1685.03
GO:0006508 proteolysis P
ISS
AthAt3g15710
At1g52600
GO:0006518 peptide metabolic process P
RCA
SceS000001461
GO:0016485 protein processing P
RCA
SceS000001461
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle
P
IMP
CelWBGene00021844
GO:0045047 protein targeting to ER P
IMP
SceS000001461
ISS
SpoSPBC1685.03
GO:0051604 protein maturation P
RCA
SceS000001461

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
55536

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SEC11A GI:7657609 P67812
Pan troglodytes (Ptr) SEC11A GI:114658678
Canis familiaris (Cfa) SEC11A GI:50979142
Mus musculus (Mmu) Sec11a
(MGI:1929464)
GI:9910550 Q6PET3
Rattus norvegicus (Rno) Sec11a GI:61889101
Gallus gallus (Gga) SEC11A GI:94536817
Schizosaccharomyces pombe (Spo) sec11
(SPBC1685.03)
GI:19111999 O74323
Saccharomyces cerevisiae (Sce) SEC11
(S000001461)
GI:6322213 P15367
Kluyveromyces lactis (Kla) KLLA0E18326g GI:50309529
Eremothecium gossypii (Ego) AGOS_ADR158W GI:45188032
Magnaporthe grisea (Mgr) MGG_00113 GI:39975481
Neurospora crassa (Ncr) NCU04519.1 GI:32406518
Arabidopsis thaliana (Ath) AT1G52600 GI:15219044
Oryza sativa (Osa) Os06g0273800 GI:115467544
Oryza sativa (Osa) Os05g0297900 GI:115463043


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1929464
GO:0005783 endoplasmic reticulum C
IDA
AthAt1g52600
SceS000001461
SpoSPBC1685.03
GO:0005787 signal peptidase complex C
IDA
SceS000001461
ISS
SpoSPBC1685.03
GO:0005886 plasma membrane C
IDA
AthAt1g52600
GO:0016020 membrane C
ISS
AthAt1g52600
GO:0003674 molecular_function F
ND
MmuMGI:1929464
GO:0005515 protein binding F
IPI
HsaSEC11A
GO:0008233 peptidase activity F
IMP
SceS000001461
ISS
AthAt1g52600
SceS000001461
SpoSPBC1685.03
GO:0006465 signal peptide processing P
IDA
SceS000001461
IMP
SceS000001461
IPI
SceS000001461
ISS
SceS000001461
SpoSPBC1685.03
GO:0006508 proteolysis P
ISS
AthAt1g52600
GO:0006518 peptide metabolic process P
RCA
SceS000001461
GO:0008150 biological_process P
ND
MmuMGI:1929464
GO:0016485 protein processing P
RCA
SceS000001461
GO:0045047 protein targeting to ER P
IMP
SceS000001461
ISS
SpoSPBC1685.03
GO:0051604 protein maturation P
RCA
SceS000001461

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1456

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga13438 ENSANGP00000013674
Anopheles gambiae (Aga) aga5345 ENSANGP00000020448
Ashbya gossypii (Ago) ago1900 ADR158W
Arabidopsis thaliana (Ath) ath4543 At1g52600.1
Arabidopsis thaliana (Ath) ath13801 At3g15710.1
Caenorhabditis elegans (Cel) cel19718 Y54E10BR.5
(CE22466;
WBGene00021844)
Candida glabrata (Cgl) cgl1518 CAGL0F06721g
Cryptococcus neoformans (Cne) cne3812 185.m02733
Dictyostelium discoideum (Ddi) ddi4008 DDB0167012
Debaryomyces hansenii (Dha) dha4042 DEHA0E18062g
Drosophila melanogaster (Dme) dme11256 CG2358-PA
(FBgn0026567)
Danio rerio (Dre) dre29417 ENSDARP00000009538
(sec11l1)
Q1LVK8
Encephalitozoon cuniculi (Ecu) ecu75 19073996
Takifugu rubripes (Fru) fru24076 SINFRUP00000148178
Gallus gallus (Gga) gga3660 ENSGALP00000003877
(SEC11A)
Q5ZMQ3
Gallus gallus (Gga) gga24097 ENSGALP00000004471
(SEC11C)
Homo sapiens (Hsa) hsa11108 ENSP00000268220
(SEC11A)
P67812
Homo sapiens (Hsa) hsa15016 ENSP00000299714
(SEC11C)
Q9BY50
Kluyveromyces lactis (Kla) kla3773 KLLA0E18326g
Mus musculus (Mmu) mmu12842 ENSMUSP00000025394
(MGI:1913536)
Q9D8V7
Mus musculus (Mmu) mmu24267 ENSMUSP00000026818
(MGI:1929464)
Q9R0P6
Neurospora crassa (Ncr) ncr4388 NCU04519.2
Oryza sativa (Osa) osa53091 6125.m00136
Oryza sativa (Osa) osa55940 6379.m00251
Oryza sativa (Osa) osa56529 6390.m00337
Plasmodium falciparum (Pfa) pfa3909 MAL13P1.167
Rattus norvegicus (Rno) rno2189 ENSRNOP00000015218
(RGD:69360)
Q6P9X2
Rattus norvegicus (Rno) rno14301 ENSRNOP00000022958
(RGD:628665)
Q9WTR7
Saccharomyces cerevisiae (Sce) sce3232 YIR022W
(S000001461)
Schizosaccharomyces pombe (Spo) spo1393 SPBC1685.03 O74323
Yarrowia lipolytica (Yli) yli2827 YALI0D02849g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1929464
MGI:1913536
GO:0005783 endoplasmic reticulum C
IDA
AthAt3g15710
At1g52600
SceS000001461
SpoSPBC1685.03
GO:0005787 signal peptidase complex C
IDA
SceS000001461
ISS
DmeFBgn0026567
PfaMAL13P1.167
SpoSPBC1685.03
GO:0005886 plasma membrane C
IDA
AthAt3g15710
At1g52600
GO:0016020 membrane C
ISS
AthAt3g15710
At1g52600
GO:0003674 molecular_function F
ND
MmuMGI:1929464
MGI:1913536
GO:0008233 peptidase activity F
IMP
SceS000001461
ISS
AthAt3g15710
At1g52600
DmeFBgn0026567
SceS000001461
SpoSPBC1685.03
GO:0000003 reproduction P
IMP
CelWBGene00021844
GO:0002119 nematode larval development P
IMP
CelWBGene00021844
GO:0006465 signal peptide processing P
IDA
SceS000001461
IMP
SceS000001461
IPI
SceS000001461
ISS
DmeFBgn0026567
SceS000001461
SpoSPBC1685.03
GO:0006508 proteolysis P
ISS
AthAt3g15710
At1g52600
GO:0006518 peptide metabolic process P
RCA
SceS000001461
GO:0008150 biological_process P
ND
MmuMGI:1913536
MGI:1929464
GO:0016485 protein processing P
RCA
SceS000001461
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle
P
IMP
CelWBGene00021844
GO:0045047 protein targeting to ER P
IMP
SceS000001461
ISS
SpoSPBC1685.03
GO:0051604 protein maturation P
RCA
SceS000001461

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC1685.03
(O74323)
YIR022W
(S000001461)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000001461
SpoSPBC1685.03
GO:0005787 signal peptidase complex C
IDA
SceS000001461
ISS
SpoSPBC1685.03
GO:0008233 peptidase activity F
IMP
SceS000001461
ISS
SceS000001461
SpoSPBC1685.03
GO:0006465 signal peptide processing P
IDA
SceS000001461
IMP
SceS000001461
IPI
SceS000001461
ISS
SceS000001461
SpoSPBC1685.03
GO:0006518 peptide metabolic process P
RCA
SceS000001461
GO:0016485 protein processing P
RCA
SceS000001461
GO:0045047 protein targeting to ER P
IMP
SceS000001461
ISS
SpoSPBC1685.03
GO:0051604 protein maturation P
RCA
SceS000001461

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk