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Search term: YIR033W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MGA2
SGD link S000001472
Alternative ID YIR033W
Description ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting
Synonyms YIR033W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3836 -CDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING HLH transcription factor EBF/Olf-1 and related DNA binding proteins

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE29366
(WBGene00006743)		 GI:17570165 Q93705
Drosophila melanogaster (Dme) 7303139 GI:17864442
Homo sapiens (Hsa) Hs12056973 GI:12056973
Homo sapiens (Hsa) Hs14782462 GI:14782462
Homo sapiens (Hsa) Hs20479830 GI:20479830
Homo sapiens (Hsa) Hs20548816 GI:20548816
Homo sapiens (Hsa) Hs22048597 GI:22048597
Homo sapiens (Hsa) Hs22052391 GI:22052391
Homo sapiens (Hsa) Hs22055401 GI:22055401
Homo sapiens (Hsa) Hs22063229 GI:22063229
Saccharomyces cerevisiae (Sce) YIR033w
(S000001472)		 GI:6322224 P40578
Saccharomyces cerevisiae (Sce) YKL020c
(S000001503)		 GI:6322832 P35210
Schizosaccharomyces pombe (Spo) SPAC26H5.05 GI:19115364 O13987


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SpoSPAC26H5.05
GO:0005634 nucleus C
IC
SceS000001503
IDA
CelWBGene00006743
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000001503
S000001472
ISS
SpoSPAC26H5.05
TAS
SceS000001503
GO:0043234 protein complex C
NAS
SpoSPAC26H5.05
GO:0003674 molecular_function F
ND
SpoSPAC26H5.05
GO:0003677 DNA binding F
IPI
SceS000001503
GO:0016563 transcription activator activity F
IMP
SceS000001472
S000001503
GO:0006414 translational elongation P
RCA
SceS000001472
GO:0006631 fatty acid metabolic process P
IMP
SceS000001503
S000001472
ISS
SpoSPAC26H5.05
GO:0009409 response to cold P
IMP
SceS000001472
S000001503
GO:0040011 locomotion P
IMP
CelWBGene00006743
GO:0040024 dauer larval development P
IGI
CelWBGene00006743
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000001472
S000001503
GO:0048666 neuron development P
IMP
CelWBGene00006743
GO:0051049 regulation of transport P
RCA
SceS000001503

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48795

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MGA2
(S000001472)		 GI:6322224 P40578
Saccharomyces cerevisiae (Sce) SPT23
(S000001503)		 GI:6322832 P35210
Kluyveromyces lactis (Kla) KLLA0E18029g GI:50309501
Eremothecium gossypii (Ego) AGOS_ACR165W GI:45185851


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000001503
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000001503
S000001472
TAS
SceS000001503
GO:0003677 DNA binding F
IPI
SceS000001503
GO:0016563 transcription activator activity F
IMP
SceS000001472
S000001503
GO:0006414 translational elongation P
RCA
SceS000001472
GO:0006631 fatty acid metabolic process P
IMP
SceS000001503
S000001472
GO:0009409 response to cold P
IMP
SceS000001472
S000001503
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000001472
S000001503
GO:0051049 regulation of transport P
RCA
SceS000001503

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_10433

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1212 ACR165W
Candida glabrata (Cgl) cgl1523 CAGL0F06831g
Cryptococcus neoformans (Cne) cne5699 179.m00562
Debaryomyces hansenii (Dha) dha3522 DEHA0E06402g
Kluyveromyces lactis (Kla) kla3759 KLLA0E18029g
Neurospora crassa (Ncr) ncr1674 NCU01722.2
Saccharomyces cerevisiae (Sce) sce3245 YIR033W
(S000001472)
Saccharomyces cerevisiae (Sce) sce3683 YKL020C
(S000001503)
Schizosaccharomyces pombe (Spo) spo1510 SPAC26H5.05 O13987
Yarrowia lipolytica (Yli) yli192 YALI0A05577g
Yarrowia lipolytica (Yli) yli1249 YALI0B12342g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SpoSPAC26H5.05
GO:0005634 nucleus C
IC
SceS000001503
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000001503
S000001472
ISS
SpoSPAC26H5.05
TAS
SceS000001503
GO:0043234 protein complex C
NAS
SpoSPAC26H5.05
GO:0003674 molecular_function F
ND
SpoSPAC26H5.05
GO:0003677 DNA binding F
IPI
SceS000001503
GO:0016563 transcription activator activity F
IMP
SceS000001472
S000001503
GO:0006414 translational elongation P
RCA
SceS000001472
GO:0006631 fatty acid metabolic process P
IMP
SceS000001503
S000001472
ISS
SpoSPAC26H5.05
GO:0009409 response to cold P
IMP
SceS000001472
S000001503
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000001472
S000001503
GO:0051049 regulation of transport P
RCA
SceS000001503

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC26H5.05
(O13987)		 YIR033W
(S000001472)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SpoSPAC26H5.05
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000001472
ISS
SpoSPAC26H5.05
GO:0043234 protein complex C
NAS
SpoSPAC26H5.05
GO:0003674 molecular_function F
ND
SpoSPAC26H5.05
GO:0016563 transcription activator activity F
IMP
SceS000001472
GO:0006414 translational elongation P
RCA
SceS000001472
GO:0006631 fatty acid metabolic process P
IMP
SceS000001472
ISS
SpoSPAC26H5.05
GO:0009409 response to cold P
IMP
SceS000001472
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000001472

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s.khadayate@ucl.ac.uk