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Search term: YIR034C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name LYS1
SGD link S000001473
Alternative ID YIR034C
Description Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway
Synonyms YIR034C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0172 ACDHYP-

KOGs classification KOGs description
METABOLISM Lysine-ketoglutarate reductase/saccharopine dehydrogenase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g33150 GI:7488325
Caenorhabditis elegans (Cel) CE18095
(WBGene00019819)		 GI:17541738 O44503
Drosophila melanogaster (Dme) 7297296 GI:19920892
Homo sapiens (Hsa) Hs13027640
(AASS)		 GI:13027640 Q9UDR5
Saccharomyces cerevisiae (Sce) YIR034c
(S000001473)		 GI:6322225 P38998
Saccharomyces cerevisiae (Sce) YNR050c
(S000005333)		 GI:6324378 P38999
Schizosaccharomyces pombe (Spo) SPAC227.18 GI:19113884 Q09694
Schizosaccharomyces pombe (Spo) SPBC3B8.03 GI:19113203 O59711
Arabidopsis thaliana (Ath) At4g33150 GI:7488325
Caenorhabditis elegans (Cel) CE18095
(WBGene00019819)		 GI:17541738 O44503
Drosophila melanogaster (Dme) 7297296 GI:19920892
Homo sapiens (Hsa) Hs13027640
(AASS)		 GI:13027640 Q9UDR5
Saccharomyces cerevisiae (Sce) YIR034c
(S000001473)		 GI:6322225 P38998
Saccharomyces cerevisiae (Sce) YNR050c
(S000005333)		 GI:6324378 P38999
Schizosaccharomyces pombe (Spo) SPAC227.18 GI:19113884 Q09694
Schizosaccharomyces pombe (Spo) SPBC3B8.03 GI:19113203 O59711
Arabidopsis thaliana (Ath) At4g33150 GI:7488325
Caenorhabditis elegans (Cel) CE18095
(WBGene00019819)		 GI:17541738 O44503
Drosophila melanogaster (Dme) 7297296 GI:19920892
Homo sapiens (Hsa) Hs13027640
(AASS)		 GI:13027640 Q9UDR5
Saccharomyces cerevisiae (Sce) YIR034c
(S000001473)		 GI:6322225 P38998
Saccharomyces cerevisiae (Sce) YNR050c
(S000005333)		 GI:6324378 P38999
Schizosaccharomyces pombe (Spo) SPAC227.18 GI:19113884 Q09694
Schizosaccharomyces pombe (Spo) SPBC3B8.03 GI:19113203 O59711


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
AthAt4g33150
SceS000005333
S000001473
SpoSPAC227.18
ISS
SpoSPAC227.18
SPBC3B8.03
GO:0005739 mitochondrion C
TAS
HsaAASS
GO:0005829 cytosol C
IDA
SpoSPBC3B8.03
GO:0004753 saccharopine dehydrogenase activity F
IDA
AthAt4g33150
GO:0004754 saccharopine dehydrogenase (NAD+,
L-lysine-forming) activity		 F
IDA
SceS000001473
ISS
SpoSPAC227.18
GO:0004755 saccharopine dehydrogenase (NADP+,
L-glutamate-forming) activity		 F
IDA
SceS000005333
ISS
SpoSPBC3B8.03
GO:0047131 saccharopine dehydrogenase (NAD+,
L-glutamate-forming) activity		 F
NAS
HsaAASS
GO:0006082 organic acid metabolic process P
RCA
SceS000001473
GO:0006414 translational elongation P
RCA
SceS000001473
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000001473
GO:0006554 lysine catabolic process P
NAS
HsaAASS
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000001473
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000001473
GO:0009085 lysine biosynthetic process P
IMP
SceS000001473
SpoSPBC3B8.03
GO:0019477 L-lysine catabolic process P
IDA
AthAt4g33150
GO:0019878 lysine biosynthetic process via aminoadipic
acid		 P
IMP
SceS000005333
SpoSPAC227.18
NAS
SceS000001473
TAS
SceS000001473
GO:0051262 protein tetramerization P
TAS
HsaAASS

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6206

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) lys3
(SPAC227.18)		 GI:19113884 Q09694
Saccharomyces cerevisiae (Sce) LYS1
(S000001473)		 GI:6322225 P38998
Kluyveromyces lactis (Kla) KLLA0E07964g GI:50308615
Eremothecium gossypii (Ego) AGOS_ACR167C GI:45185853
Magnaporthe grisea (Mgr) MGG_01359 GI:39951433
Neurospora crassa (Ncr) NCU03118.1 GI:32420221


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001473
SpoSPAC227.18
ISS
SpoSPAC227.18
GO:0004754 saccharopine dehydrogenase (NAD+,
L-lysine-forming) activity		 F
IDA
SceS000001473
ISS
SpoSPAC227.18
GO:0006082 organic acid metabolic process P
RCA
SceS000001473
GO:0006414 translational elongation P
RCA
SceS000001473
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000001473
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000001473
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000001473
GO:0009085 lysine biosynthetic process P
IMP
SceS000001473
GO:0019878 lysine biosynthetic process via aminoadipic
acid		 P
IMP
SpoSPAC227.18
NAS
SceS000001473
TAS
SceS000001473

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_13301

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1214 ACR167C
Candida glabrata (Cgl) cgl1525 CAGL0F06875g
Cryptococcus neoformans (Cne) cne449 163.m06411
Debaryomyces hansenii (Dha) dha1774 DEHA0C07832g
Kluyveromyces lactis (Kla) kla3309 KLLA0E07964g
Neurospora crassa (Ncr) ncr3022 NCU03118.2
Saccharomyces cerevisiae (Sce) sce3246 YIR034C
(S000001473)
Schizosaccharomyces pombe (Spo) spo4583 SPAC227.18 Q09694
Yarrowia lipolytica (Yli) yli1384 YALI0B15444g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001473
SpoSPAC227.18
ISS
SpoSPAC227.18
GO:0004754 saccharopine dehydrogenase (NAD+,
L-lysine-forming) activity		 F
IDA
SceS000001473
ISS
SpoSPAC227.18
GO:0006082 organic acid metabolic process P
RCA
SceS000001473
GO:0006414 translational elongation P
RCA
SceS000001473
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000001473
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000001473
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000001473
GO:0009085 lysine biosynthetic process P
IMP
SceS000001473
GO:0019878 lysine biosynthetic process via aminoadipic
acid		 P
IMP
SpoSPAC227.18
NAS
SceS000001473
TAS
SceS000001473

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC227.18
(Q09694)		 YIR034C
(S000001473)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001473
SpoSPAC227.18
ISS
SpoSPAC227.18
GO:0004754 saccharopine dehydrogenase (NAD+,
L-lysine-forming) activity		 F
IDA
SceS000001473
ISS
SpoSPAC227.18
GO:0006082 organic acid metabolic process P
RCA
SceS000001473
GO:0006414 translational elongation P
RCA
SceS000001473
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000001473
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000001473
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000001473
GO:0009085 lysine biosynthetic process P
IMP
SceS000001473
GO:0019878 lysine biosynthetic process via aminoadipic
acid		 P
IMP
SpoSPAC227.18
NAS
SceS000001473
TAS
SceS000001473

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GO info in one table:

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