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Search term: YIR036C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name IRC24
SGD link S000001475
Alternative ID YIR036C
Description Putative benzil reductase;(GFP)-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS; sequence similarity with short-chain dehydrogenase/reductases; null mutant has increased spontaneous Rad52p foci
Synonyms YIR036C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1204 --DHYP-

KOGs classification KOGs description
METABOLISM Predicted dehydrogenase

Species KOG link NCBI link UniProt link
Drosophila melanogaster (Dme) 7290936 GI:17530855
Drosophila melanogaster (Dme) 7290937 GI:7290937
Homo sapiens (Hsa) Hs4507185
(SPR)
GI:4507185 P35270
Homo sapiens (Hsa) Hs17443898 GI:17443898
Saccharomyces cerevisiae (Sce) YIR035c GI:6322226 P40579
Saccharomyces cerevisiae (Sce) YIR036c
(S000001475)
GI:6322227 P40580
Schizosaccharomyces pombe (Spo) SPBC30D10.05c GI:19113072 O14351
Drosophila melanogaster (Dme) 7290936 GI:17530855
Drosophila melanogaster (Dme) 7290937 GI:7290937
Homo sapiens (Hsa) Hs4507185
(SPR)
GI:4507185 P35270
Homo sapiens (Hsa) Hs17443898 GI:17443898
Saccharomyces cerevisiae (Sce) YIR035c GI:6322226 P40579
Saccharomyces cerevisiae (Sce) YIR036c
(S000001475)
GI:6322227 P40580
Schizosaccharomyces pombe (Spo) SPBC30D10.05c GI:19113072 O14351


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC30D10.05c
GO:0005737 cytoplasm C
IDA
SceYIR035c
S000001475
GO:0005829 cytosol C
IDA
SpoSPBC30D10.05c
GO:0003674 molecular_function F
ND
SceYIR035c
S000001475
GO:0004033 aldo-keto reductase activity F
TAS
HsaSPR
GO:0004757 sepiapterin reductase activity F
ISS
HsaSPR
SpoSPBC30D10.05c
GO:0016491 oxidoreductase activity F
RCA
SceYIR035c
GO:0050661 NADP or NADPH binding F
TAS
HsaSPR
GO:0006729 tetrahydrobiopterin biosynthetic
process
P
ISS
SpoSPBC30D10.05c
TAS
HsaSPR
GO:0006809 nitric oxide biosynthetic process P
IDA
HsaSPR
GO:0008150 biological_process P
ND
SceS000001475
YIR035c
GO:0055114 oxidation reduction P
TAS
HsaSPR

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74713

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) IRC24
(S000001475)
GI:6322227 P40580
Kluyveromyces lactis (Kla) KLLA0E08052g GI:50308623


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001475
GO:0003674 molecular_function F
ND
SceS000001475
GO:0008150 biological_process P
ND
SceS000001475

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2192

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga9976 ENSANGP00000025342
Ashbya gossypii (Ago) ago1218 ACR171C
Candida glabrata (Cgl) cgl1526 CAGL0F06897g
Candida glabrata (Cgl) cgl1527 CAGL0F06919g
Cryptococcus neoformans (Cne) cne4266 177.m03023
Dictyostelium discoideum (Ddi) ddi13039 DDB0191275
Debaryomyces hansenii (Dha) dha2961 DEHA0D14784g
Drosophila melanogaster (Dme) dme16996 CG12117-PA
(FBgn0014032)
Danio rerio (Dre) dre14007 ENSDARP00000002775 Q2LCL8
Escherichia coli (Eco) eco1234 16129232
Takifugu rubripes (Fru) fru11491 SINFRUP00000148435
Takifugu rubripes (Fru) fru1605 SINFRUP00000162674
Gallus gallus (Gga) gga24419 ENSGALP00000000091
(SPR)
Homo sapiens (Hsa) hsa17980 ENSP00000234454
(SPR)
P35270
Kluyveromyces lactis (Kla) kla3313 KLLA0E08052g
Kluyveromyces lactis (Kla) kla3314 KLLA0E08063g
Mus musculus (Mmu) mmu22223 ENSMUSP00000048111
(MGI:103078)
Q64105
Neurospora crassa (Ncr) ncr1962 NCU02018.2
Rattus norvegicus (Rno) rno21742 ENSRNOP00000020749
(RGD:3753)
P18297
Rattus norvegicus (Rno) rno21743 ENSRNOP00000030860
Saccharomyces cerevisiae (Sce) sce3247 YIR035C
Saccharomyces cerevisiae (Sce) sce3248 YIR036C
(S000001475)
Schizosaccharomyces pombe (Spo) spo1736 SPBC30D10.05c O14351
Yarrowia lipolytica (Yli) yli2788 YALI0D01980g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC30D10.05c
GO:0005737 cytoplasm C
IDA
SceYIR035c
S000001475
GO:0005739 mitochondrion C
IDA
MmuMGI:103078
GO:0005829 cytosol C
IDA
SpoSPBC30D10.05c
GO:0003674 molecular_function F
ND
SceYIR035c
S000001475
GO:0004757 sepiapterin reductase activity F
IDA
DmeFBgn0014032
ISO
MmuMGI:103078
ISS
DmeFBgn0014032
SpoSPBC30D10.05c
GO:0016491 oxidoreductase activity F
RCA
SceYIR035c
GO:0006558 L-phenylalanine metabolic process P
IMP
MmuMGI:103078
GO:0006729 tetrahydrobiopterin biosynthetic
process
P
ISO
MmuMGI:103078
ISS
SpoSPBC30D10.05c
GO:0008150 biological_process P
ND
SceS000001475
YIR035c
GO:0010033 response to organic substance P
ISO
MmuMGI:103078
GO:0016265 death P
IMP
MmuMGI:103078
GO:0019889 pteridine metabolic process P
IMP
MmuMGI:103078
GO:0040014 regulation of multicellular organism
growth
P
IMP
MmuMGI:103078
GO:0042415 norepinephrine metabolic process P
IMP
MmuMGI:103078
GO:0042417 dopamine metabolic process P
IMP
MmuMGI:103078
GO:0042428 serotonin metabolic process P
IMP
MmuMGI:103078
GO:0046146 tetrahydrobiopterin metabolic process P
IMP
MmuMGI:103078
GO:0048667 cell morphogenesis involved in neuron
differentiation
P
IMP
MmuMGI:103078
GO:0050882 voluntary musculoskeletal movement P
IMP
MmuMGI:103078

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC30D10.05c
(O14351)
YIR036C
(S000001475)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC30D10.05c
GO:0005737 cytoplasm C
IDA
SceS000001475
GO:0005829 cytosol C
IDA
SpoSPBC30D10.05c
GO:0003674 molecular_function F
ND
SceS000001475
GO:0004757 sepiapterin reductase activity F
ISS
SpoSPBC30D10.05c
GO:0006729 tetrahydrobiopterin biosynthetic
process
P
ISS
SpoSPBC30D10.05c
GO:0008150 biological_process P
ND
SceS000001475

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s.khadayate@ucl.ac.uk