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Search term: YIR037W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HYR1
SGD link S000001476
Alternative ID YIR037W
Description Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor
Synonyms YIR037W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1651 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Glutathione peroxidase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g63460 GI:18407822
Arabidopsis thaliana (Ath) At2g25080 GI:15224678
Arabidopsis thaliana (Ath) At2g31570 GI:15225103
Arabidopsis thaliana (Ath) At2g43350 GI:15224272
Arabidopsis thaliana (Ath) At2g48150 GI:15227231
Arabidopsis thaliana (Ath) At3g63080 GI:15229378
Arabidopsis thaliana (Ath) At4g11600 GI:15234243
Arabidopsis thaliana (Ath) At4g31870 GI:15236550
Caenorhabditis elegans (Cel) CE07402 GI:17569211
Caenorhabditis elegans (Cel) CE08101 GI:17550318
Caenorhabditis elegans (Cel) CE08102
(WBGene00007517)		 GI:17550320 Q95003
Caenorhabditis elegans (Cel) CE09696
(WBGene00009165)		 GI:17506887 O02621
Caenorhabditis elegans (Cel) CE17114
(WBGene00018850)		 GI:17507603 Q9N5S2
Caenorhabditis elegans (Cel) CE17231 GI:17542290
Caenorhabditis elegans (Cel) CE18107
(WBGene00011045)		 GI:17535473 O62327
Caenorhabditis elegans (Cel) CE25634 GI:17544270
Drosophila melanogaster (Dme) 7292354 GI:7292354
Drosophila melanogaster (Dme) 7302524 GI:7302524
Homo sapiens (Hsa) Hs4557629
(GPX5)		 GI:4557629 O75715
Homo sapiens (Hsa) Hs4504107 GI:4504107
Homo sapiens (Hsa) Hs6715602 GI:6715602 O75715
Homo sapiens (Hsa) Hs20555772 GI:20555772
Homo sapiens (Hsa) Hs10834976 GI:10834976
Homo sapiens (Hsa) Hs15618997
(GPX7)		 GI:15618997 Q96SL4
Homo sapiens (Hsa) Hs4504103 GI:4504103
Homo sapiens (Hsa) Hs6006001
(GPX3)		 GI:6006001 P22352
Saccharomyces cerevisiae (Sce) YBR244w
(S000000448)		 GI:6319721 P38143
Saccharomyces cerevisiae (Sce) YIR037w
(S000001476)		 GI:6322228 P40581
Saccharomyces cerevisiae (Sce) YKL026c
(S000001509)		 GI:6322826 P36014
Schizosaccharomyces pombe (Spo) SPBC32F12.03c GI:19112938 O59858
Encephalitozoon cuniculi (Ecu) ECU02g0440 GI:19073965 Q8SSH7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g63460
SceS000001509
GO:0005615 extracellular space C
IDA
HsaGPX3
GO:0005622 intracellular C
IPI
SceS000001476
GO:0005634 nucleus C
IDA
SceS000000448
SpoSPBC32F12.03c
GO:0005737 cytoplasm C
IDA
SceS000000448
SpoSPBC32F12.03c
GO:0005739 mitochondrion C
IDA
AthAt4g11600
ISS
AthAt2g43350
TAS
AthAt4g11600
GO:0005783 endoplasmic reticulum C
ISS
AthAt3g63080
GO:0005829 cytosol C
IDA
SpoSPBC32F12.03c
NAS
AthAt2g31570
At2g48150
TAS
AthAt4g11600
GO:0005886 plasma membrane C
IDA
AthAt4g11600
At3g63080
GO:0009507 chloroplast C
IDA
AthAt4g11600
At2g25080
ISS
AthAt2g25080
At4g31870
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt2g25080
GO:0009570 chloroplast stroma C
IDA
AthAt2g25080
GO:0009941 chloroplast envelope C
IDA
AthAt2g25080
GO:0004602 glutathione peroxidase activity F
IDA
HsaGPX3
SceS000001509
S000000448
IMP
SceS000001509
S000001476
S000000448
ISS
AthAt4g31870
At2g43350
At2g25080
At1g63460
At2g31570
At4g11600
At2g48150
At3g63080
SceS000001476
S000001509
S000000448
TAS
SpoSPBC32F12.03c
GO:0008134 transcription factor binding F
TAS
HsaGPX3
GO:0008379 thioredoxin peroxidase activity F
TAS
SceS000001476
GO:0008430 selenium binding F
IDA
HsaGPX3
GO:0047066 phospholipid-hydroperoxide glutathione peroxidase
activity		 F
IDA
SceS000001509
S000001476
S000000448
IMP
SceS000001509
S000000448
S000001476
GO:0006414 translational elongation P
RCA
SceS000000448
GO:0006629 lipid metabolic process P
NAS
HsaGPX5
GO:0006790 sulfur metabolic process P
NAS
SpoSPBC32F12.03c
GO:0006970 response to osmotic stress P
IEP
SpoSPBC32F12.03c
GO:0006982 response to lipid hydroperoxide P
TAS
HsaGPX3
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000001476
GO:0009651 response to salt stress P
IEP
AthAt4g11600
GO:0009738 abscisic acid mediated signaling
pathway		 P
IMP
AthAt2g43350
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt3g63080
GO:0019430 removal of superoxide radicals P
IC
SpoSPBC32F12.03c
GO:0034599 cellular response to oxidative
stress		 P
IEP
SpoSPBC32F12.03c
IMP
SceS000001509
S000001476
S000000448
GO:0034605 cellular response to heat P
IEP
SpoSPBC32F12.03c
GO:0042542 response to hydrogen peroxide P
IMP
AthAt2g43350
GO:0042631 cellular response to water deprivation P
IMP
AthAt2g43350
GO:0042744 hydrogen peroxide catabolic process P
TAS
HsaGPX3
GO:0046686 response to cadmium ion P
IEP
AthAt4g11600
GO:0051289 protein homotetramerization P
IDA
HsaGPX3
GO:0070301 cellular response to hydrogen peroxide P
IGI
SpoSPBC32F12.03c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
90937

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GPX7 GI:15618997 Q96SL4
Pan troglodytes (Ptr) GPX7 GI:114556636
Canis familiaris (Cfa) GPX7 GI:73977503
Mus musculus (Mmu) Gpx7
(MGI:1914555)		 GI:13195626 Q3TNK3
Rattus norvegicus (Rno) Gpx7 GI:27715595
Gallus gallus (Gga) GPX7 GI:118094662
Caenorhabditis elegans (Cel) T09A12.2
(CE31060;
WBGene00020373)		 GI:71993584
Caenorhabditis elegans (Cel) R03G5.5
(CE41834;
WBGene00019846)		 GI:193210707
Schizosaccharomyces pombe (Spo) gpx1
(SPBC32F12.03c)		 GI:19112938 O59858
Saccharomyces cerevisiae (Sce) HYR1
(S000001476)		 GI:6322228 P40581
Kluyveromyces lactis (Kla) KLLA0F06732g GI:50310727
Eremothecium gossypii (Ego) AGOS_AFL039C GI:45198480
Magnaporthe grisea (Mgr) MGG_07460 GI:145609259
Neurospora crassa (Ncr) NCU09534.1 GI:32418830
Arabidopsis thaliana (Ath) ATGPX6 GI:30681827
Oryza sativa (Osa) Os02g0664000 GI:115447759
Oryza sativa (Osa) Os04g0556300 GI:115459848
Plasmodium falciparum (Pfa) PFL0595c GI:124805752


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
IPI
SceS000001476
GO:0005634 nucleus C
IDA
SpoSPBC32F12.03c
GO:0005737 cytoplasm C
IDA
SpoSPBC32F12.03c
GO:0005739 mitochondrion C
IDA
AthATGPX6
TAS
AthATGPX6
GO:0005829 cytosol C
IDA
SpoSPBC32F12.03c
TAS
AthATGPX6
GO:0005886 plasma membrane C
IDA
AthATGPX6
GO:0009507 chloroplast C
IDA
AthATGPX6
GO:0020011 apicoplast C
ISS
PfaPFL0595c
GO:0004602 glutathione peroxidase activity F
IMP
SceS000001476
ISS
AthATGPX6
SceS000001476
TAS
SpoSPBC32F12.03c
GO:0008379 thioredoxin peroxidase activity F
TAS
SceS000001476
GO:0047066 phospholipid-hydroperoxide glutathione peroxidase
activity		 F
IDA
SceS000001476
IMP
SceS000001476
GO:0006790 sulfur metabolic process P
NAS
SpoSPBC32F12.03c
GO:0006970 response to osmotic stress P
IEP
SpoSPBC32F12.03c
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000001476
GO:0009651 response to salt stress P
IEP
AthATGPX6
GO:0019430 removal of superoxide radicals P
IC
SpoSPBC32F12.03c
GO:0034599 cellular response to oxidative
stress		 P
IEP
SpoSPBC32F12.03c
IMP
SceS000001476
GO:0034605 cellular response to heat P
IEP
SpoSPBC32F12.03c
GO:0046686 response to cadmium ion P
IEP
AthATGPX6
GO:0070301 cellular response to hydrogen peroxide P
IGI
SpoSPBC32F12.03c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_335

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6775 ENSANGP00000013962
Anopheles gambiae (Aga) aga6776 ENSANGP00000024750
Anopheles gambiae (Aga) aga6774 ENSANGP00000026930
Ashbya gossypii (Ago) ago3154 AFL039C
Arabidopsis thaliana (Ath) ath9424 At2g25080.1
Arabidopsis thaliana (Ath) ath10156 At2g31570.1
Arabidopsis thaliana (Ath) ath11528 At2g43350.1
Arabidopsis thaliana (Ath) ath12081 At2g48150.1
Arabidopsis thaliana (Ath) ath17761 At3g63080.1
Arabidopsis thaliana (Ath) ath18900 At4g11600.1
Arabidopsis thaliana (Ath) ath21272 At4g31870.1
Caenorhabditis elegans (Cel) cel7380 F26E4.12
(CE09696;
WBGene00009165)
Caenorhabditis elegans (Cel) cel13392 R05H10.5
(CE18107;
WBGene00011045)
Caenorhabditis elegans (Cel) cel15064 T09A12.2b
(CE17231)
Candida glabrata (Cgl) cgl489 CAGL0C01705g
Candida glabrata (Cgl) cgl2534 CAGL0I00242g
Candida glabrata (Cgl) cgl2535 CAGL0I00264g
Cryptococcus neoformans (Cne) cne2928 167.m03214
Cryptococcus neoformans (Cne) cne2668 183.m01603
Debaryomyces hansenii (Dha) dha1835 DEHA0C09196g
Debaryomyces hansenii (Dha) dha4845 DEHA0F10439g
Drosophila melanogaster (Dme) dme7782 CG12013-PA
(FBgn0035438)
Drosophila melanogaster (Dme) dme7780 CG12013-PB
(FBgn0035438)
Drosophila melanogaster (Dme) dme7781 CG12013-PC
(FBgn0035438)
Drosophila melanogaster (Dme) dme7783 CG12013-PD
(FBgn0035438)
Drosophila melanogaster (Dme) dme5972 CG15116-PA
(FBgn0034415)
Danio rerio (Dre) dre15465 ENSDARP00000008425
(zgc:112293)		 Q502E1
Escherichia coli (Eco) eco1668 16129666
Encephalitozoon cuniculi (Ecu) ecu44 19073965
Takifugu rubripes (Fru) fru802 SINFRUP00000136183
Takifugu rubripes (Fru) fru8260 SINFRUP00000142386
Gallus gallus (Gga) gga22806 ENSGALP00000017282
(GPX7)
Gallus gallus (Gga) gga26648 ENSGALP00000022024
(GPX8)
Homo sapiens (Hsa) hsa1172 ENSP00000262661
Homo sapiens (Hsa) hsa25234 ENSP00000296734
(GPX8)		 Q8TED1
Homo sapiens (Hsa) hsa15200 ENSP00000346103
(GPX4)		 P36969-1
Kluyveromyces lactis (Kla) kla2238 KLLA0D03905g
Kluyveromyces lactis (Kla) kla4385 KLLA0F06732g
Mus musculus (Mmu) mmu7564 ENSMUSP00000022282
(MGI:1916840)		 Q9D7B7
Mus musculus (Mmu) mmu18586 ENSMUSP00000030332
(MGI:1914555)		 Q99LJ6
Neurospora crassa (Ncr) ncr9282 NCU09534.2
Oryza sativa (Osa) osa6552 2454.m00145
Oryza sativa (Osa) osa32588 4464.m00145
Oryza sativa (Osa) osa35769 4803.m00052
Oryza sativa (Osa) osa54645 6314.m00183
Oryza sativa (Osa) osa58920 6473.m00129
Oryza sativa (Osa) osa83163 8287.m00116
Plasmodium falciparum (Pfa) pfa4905 PFL0595c
Rattus norvegicus (Rno) rno23610 ENSRNOP00000013913
(RGD:1306999)
Rattus norvegicus (Rno) rno15521 ENSRNOP00000013979
(RGD:1307506)
Rattus norvegicus (Rno) rno26288 ENSRNOP00000018691
(RGD:69226)		 P36970-1
Rattus norvegicus (Rno) rno26289 ENSRNOP00000027557
Saccharomyces cerevisiae (Sce) sce520 YBR244W
(S000000448)
Saccharomyces cerevisiae (Sce) sce3250 YIR037W
(S000001476)
Saccharomyces cerevisiae (Sce) sce3689 YKL026C
(S000001509)
Schizosaccharomyces pombe (Spo) spo4510 SPBC32F12.03c O59858
Yarrowia lipolytica (Yli) yli3956 YALI0E02310g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1916840
SceS000001509
GO:0005622 intracellular C
IPI
SceS000001476
GO:0005634 nucleus C
IDA
SceS000000448
SpoSPBC32F12.03c
GO:0005737 cytoplasm C
IDA
SceS000000448
SpoSPBC32F12.03c
ISS
DmeFBgn0035438
GO:0005739 mitochondrion C
IDA
AthAt4g11600
ISS
AthAt2g43350
DmeFBgn0035438
TAS
AthAt4g11600
GO:0005783 endoplasmic reticulum C
ISS
AthAt3g63080
GO:0005829 cytosol C
IDA
SpoSPBC32F12.03c
NAS
AthAt2g31570
At2g48150
TAS
AthAt4g11600
GO:0005886 plasma membrane C
IDA
AthAt4g11600
At3g63080
GO:0009507 chloroplast C
IDA
AthAt4g11600
At2g25080
ISS
AthAt2g25080
At4g31870
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt2g25080
GO:0009570 chloroplast stroma C
IDA
AthAt2g25080
GO:0009941 chloroplast envelope C
IDA
AthAt2g25080
GO:0020011 apicoplast C
ISS
PfaPFL0595c
GO:0003674 molecular_function F
ND
MmuMGI:1916840
GO:0004601 peroxidase activity F
IDA
DmeFBgn0035438
GO:0004602 glutathione peroxidase activity F
IDA
SceS000001509
S000000448
IMP
SceS000001509
S000001476
S000000448
ISS
AthAt4g31870
At2g43350
At2g25080
At2g31570
At4g11600
At2g48150
At3g63080
DmeFBgn0035438
FBgn0034415
SceS000001476
S000001509
S000000448
TAS
SpoSPBC32F12.03c
GO:0008379 thioredoxin peroxidase activity F
TAS
SceS000001476
GO:0047066 phospholipid-hydroperoxide glutathione peroxidase
activity		 F
IDA
SceS000001509
S000001476
S000000448
IMP
SceS000001509
S000000448
S000001476
GO:0006414 translational elongation P
RCA
SceS000000448
GO:0006790 sulfur metabolic process P
NAS
SpoSPBC32F12.03c
GO:0006970 response to osmotic stress P
IEP
SpoSPBC32F12.03c
GO:0006982 response to lipid hydroperoxide P
ISS
DmeFBgn0035438
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000001476
GO:0008150 biological_process P
ND
MmuMGI:1916840
GO:0009651 response to salt stress P
IEP
AthAt4g11600
GO:0009738 abscisic acid mediated signaling
pathway		 P
IMP
AthAt2g43350
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt3g63080
GO:0019430 removal of superoxide radicals P
IC
SpoSPBC32F12.03c
GO:0034599 cellular response to oxidative
stress		 P
IEP
SpoSPBC32F12.03c
IMP
SceS000001509
S000001476
S000000448
GO:0034605 cellular response to heat P
IEP
SpoSPBC32F12.03c
GO:0042542 response to hydrogen peroxide P
IMP
AthAt2g43350
GO:0042631 cellular response to water deprivation P
IMP
AthAt2g43350
GO:0046686 response to cadmium ion P
IEP
AthAt4g11600
GO:0070301 cellular response to hydrogen peroxide P
IGI
SpoSPBC32F12.03c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC32F12.03c
(O59858)		 YIR037W
(S000001476)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
IPI
SceS000001476
GO:0005634 nucleus C
IDA
SpoSPBC32F12.03c
GO:0005737 cytoplasm C
IDA
SpoSPBC32F12.03c
GO:0005829 cytosol C
IDA
SpoSPBC32F12.03c
GO:0004602 glutathione peroxidase activity F
IMP
SceS000001476
ISS
SceS000001476
TAS
SpoSPBC32F12.03c
GO:0008379 thioredoxin peroxidase activity F
TAS
SceS000001476
GO:0047066 phospholipid-hydroperoxide glutathione peroxidase
activity		 F
IDA
SceS000001476
IMP
SceS000001476
GO:0006790 sulfur metabolic process P
NAS
SpoSPBC32F12.03c
GO:0006970 response to osmotic stress P
IEP
SpoSPBC32F12.03c
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000001476
GO:0019430 removal of superoxide radicals P
IC
SpoSPBC32F12.03c
GO:0034599 cellular response to oxidative
stress		 P
IEP
SpoSPBC32F12.03c
IMP
SceS000001476
GO:0034605 cellular response to heat P
IEP
SpoSPBC32F12.03c
GO:0070301 cellular response to hydrogen peroxide P
IGI
SpoSPBC32F12.03c

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GO info in one table:

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