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Search term: YJL012C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name VTC4
SGD link S000003549
Alternative ID YJL012C
Description Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) complex involved in synthesis and transfer of polyP to the vacuole; regulates membrane trafficking; role in non-autophagic vacuolar fusion
Synonyms YJL012C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1161 A---YPE

KOGs classification KOGs description
METABOLISM Protein involved in vacuolar polyphosphate accumulation, contains SPX domain

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g63010_1 GI:15221651
Arabidopsis thaliana (Ath) At2g26660 GI:15225770
Arabidopsis thaliana (Ath) At2g45130 GI:15225414
Arabidopsis thaliana (Ath) At4g11810_1 GI:15234311
Arabidopsis thaliana (Ath) At4g22990_1 GI:7486569
Arabidopsis thaliana (Ath) At5g15330 GI:11358467
Arabidopsis thaliana (Ath) At5g20150 GI:15241275
Saccharomyces cerevisiae (Sce) YFL004w_1 GI:14318518 P43585
Saccharomyces cerevisiae (Sce) YGR233c_1 GI:6321672 P17442
Saccharomyces cerevisiae (Sce) YJL012c
(S000003549)		 GI:6322448
Saccharomyces cerevisiae (Sce) YPL019c_1 GI:6325238 Q02725
Schizosaccharomyces pombe (Spo) SPAC14C4.11_1 GI:19115828 O13718
Schizosaccharomyces pombe (Spo) SPCC1322.14c_1 GI:19075642 P78810
Encephalitozoon cuniculi (Ecu) ECU06g1420i_1 GI:19074392 Q8SRN4
Arabidopsis thaliana (Ath) At1g63010_1 GI:15221651
Arabidopsis thaliana (Ath) At2g26660 GI:15225770
Arabidopsis thaliana (Ath) At2g45130 GI:15225414
Arabidopsis thaliana (Ath) At4g11810_1 GI:15234311
Arabidopsis thaliana (Ath) At4g22990_1 GI:7486569
Arabidopsis thaliana (Ath) At5g15330 GI:11358467
Arabidopsis thaliana (Ath) At5g20150 GI:15241275
Saccharomyces cerevisiae (Sce) YFL004w_1 GI:14318518 P43585
Saccharomyces cerevisiae (Sce) YGR233c_1 GI:6321672 P17442
Saccharomyces cerevisiae (Sce) YJL012c
(S000003549)		 GI:6322448
Saccharomyces cerevisiae (Sce) YPL019c_1 GI:6325238 Q02725
Schizosaccharomyces pombe (Spo) SPAC14C4.11_1 GI:19115828 O13718
Schizosaccharomyces pombe (Spo) SPCC1322.14c_1 GI:19075642 P78810
Encephalitozoon cuniculi (Ecu) ECU06g1420i_1 GI:19074392 Q8SRN4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000325 plant-type vacuole C
IDA
AthAt1g63010
GO:0000329 fungal-type vacuole membrane C
ISS
SpoSPCC1322.14c
SPAC14C4.11
GO:0005575 cellular_component C
ND
AthAt4g11810
At5g15330
At2g45130
At4g22990
GO:0005634 nucleus C
IDA
AthAt2g26660
At5g20150
GO:0005774 vacuolar membrane C
IDA
AthAt1g63010
GO:0005783 endoplasmic reticulum C
IDA
SceS000003549
SpoSPCC1322.14c
GO:0031310 intrinsic to vacuolar membrane C
IDA
SceS000003549
GO:0033254 vacuolar transporter chaperone
complex		 C
IPI
SceS000003549
GO:0003674 molecular_function F
ND
AthAt2g26660
At4g22990
At5g15330
At5g20150
At4g11810
At2g45130
SpoSPCC1322.14c
SPAC14C4.11
GO:0008976 polyphosphate kinase activity F
IDA
SceS000003549
GO:0006797 polyphosphate metabolic process P
IMP
SceS000003549
NAS
SpoSPAC14C4.11
GO:0006914 autophagy P
ISS
SpoSPAC14C4.11
GO:0007034 vacuolar transport P
IDA
SceS000003549
IMP
SceS000003549
ISS
SpoSPAC14C4.11
SPCC1322.14c
GO:0008150 biological_process P
ND
AthAt4g11810
At4g22990
GO:0016036 cellular response to phosphate
starvation		 P
IEP
AthAt2g26660
At5g15330
At5g20150
At2g45130
GO:0016237 microautophagy P
IDA
SceS000003549
IMP
SceS000003549
GO:0042144 vacuole fusion, non-autophagic P
IMP
SceS000003549
ISS
SpoSPAC14C4.11
SPCC1322.14c
GO:0080040 positive regulation of cellular response to
phosphate starvation		 P
IMP
AthAt5g20150
At2g45130

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6265

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) vtc4
(SPCC1322.14c)		 GI:19075642 P78810
Saccharomyces cerevisiae (Sce) VTC4
(S000003549)		 GI:42742256
Kluyveromyces lactis (Kla) KLLA0F22627g GI:50312119
Eremothecium gossypii (Ego) AGOS_AGR316C GI:45201412
Magnaporthe grisea (Mgr) MGG_09291 GI:145605419
Neurospora crassa (Ncr) NCU08110.1 GI:32416676


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
ISS
SpoSPCC1322.14c
GO:0005783 endoplasmic reticulum C
IDA
SceS000003549
SpoSPCC1322.14c
GO:0031310 intrinsic to vacuolar membrane C
IDA
SceS000003549
GO:0033254 vacuolar transporter chaperone
complex		 C
IPI
SceS000003549
GO:0003674 molecular_function F
ND
SpoSPCC1322.14c
GO:0008976 polyphosphate kinase activity F
IDA
SceS000003549
GO:0006797 polyphosphate metabolic process P
IMP
SceS000003549
GO:0007034 vacuolar transport P
IDA
SceS000003549
IMP
SceS000003549
ISS
SpoSPCC1322.14c
GO:0016237 microautophagy P
IDA
SceS000003549
IMP
SceS000003549
GO:0042144 vacuole fusion, non-autophagic P
IMP
SceS000003549
ISS
SpoSPCC1322.14c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_5285

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago4627 AGR316C
Candida glabrata (Cgl) cgl1924 CAGL0G06952g
Cryptococcus neoformans (Cne) cne974 163.m06448
Debaryomyces hansenii (Dha) dha6707 DEHA0G22594g
Encephalitozoon cuniculi (Ecu) ecu1619 19074392
Gallus gallus (Gga) gga22294 ENSGALP00000006233
Kluyveromyces lactis (Kla) kla5091 KLLA0F22627g
Neurospora crassa (Ncr) ncr7902 NCU08110.2
Plasmodium falciparum (Pfa) pfa2954 PFF1075w
Saccharomyces cerevisiae (Sce) sce3269 YJL012C
(S000003549)
Schizosaccharomyces pombe (Spo) spo4437 SPCC1322.14c P78810
Yarrowia lipolytica (Yli) yli2170 YALI0C10945g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
ISS
SpoSPCC1322.14c
GO:0005783 endoplasmic reticulum C
IDA
SceS000003549
SpoSPCC1322.14c
GO:0031310 intrinsic to vacuolar membrane C
IDA
SceS000003549
GO:0033254 vacuolar transporter chaperone
complex		 C
IPI
SceS000003549
GO:0003674 molecular_function F
ND
SpoSPCC1322.14c
GO:0008976 polyphosphate kinase activity F
IDA
SceS000003549
GO:0006797 polyphosphate metabolic process P
IMP
SceS000003549
GO:0007034 vacuolar transport P
IDA
SceS000003549
IMP
SceS000003549
ISS
SpoSPCC1322.14c
GO:0016237 microautophagy P
IDA
SceS000003549
IMP
SceS000003549
GO:0042144 vacuole fusion, non-autophagic P
IMP
SceS000003549
ISS
SpoSPCC1322.14c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1322.14c
(P78810)		 YJL012C
(S000003549)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
ISS
SpoSPCC1322.14c
GO:0005783 endoplasmic reticulum C
IDA
SceS000003549
SpoSPCC1322.14c
GO:0031310 intrinsic to vacuolar membrane C
IDA
SceS000003549
GO:0033254 vacuolar transporter chaperone
complex		 C
IPI
SceS000003549
GO:0003674 molecular_function F
ND
SpoSPCC1322.14c
GO:0008976 polyphosphate kinase activity F
IDA
SceS000003549
GO:0006797 polyphosphate metabolic process P
IMP
SceS000003549
GO:0007034 vacuolar transport P
IDA
SceS000003549
IMP
SceS000003549
ISS
SpoSPCC1322.14c
GO:0016237 microautophagy P
IDA
SceS000003549
IMP
SceS000003549
GO:0042144 vacuole fusion, non-autophagic P
IMP
SceS000003549
ISS
SpoSPCC1322.14c

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