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Search term: YJL053W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PEP8
SGD link S000003589
Alternative ID YJL053W
Description Vacuolar protein sorting protein that forms part of the multimeric membrane-associated retromer complex along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport
Synonyms YJL053W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3063 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Membrane coat complex Retromer, subunit VPS26

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g27690 GI:15234244
Arabidopsis thaliana (Ath) At5g53530 GI:15238773
Caenorhabditis elegans (Cel) CE28684
(WBGene00006931)		 GI:17542452 O01258
Drosophila melanogaster (Dme) 7290217 GI:13124625
Homo sapiens (Hsa) Hs16418381
(VPS26B)		 GI:16418381 Q4G0F5
Homo sapiens (Hsa) Hs17978519
(VPS26A)		 GI:17978519 O75436
Homo sapiens (Hsa) Hs22044968 GI:22044968
Saccharomyces cerevisiae (Sce) YJL053w
(S000003589)		 GI:6322408 P40335
Schizosaccharomyces pombe (Spo) SPAC4G9.13c GI:19114607 Q10243


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC4G9.13c
GO:0005768 endosome C
IMP
SpoSPAC4G9.13c
IPI
SceS000003589
ISS
SpoSPAC4G9.13c
GO:0005771 multivesicular body C
IDA
AthAt5g53530
GO:0005792 microsome C
IDA
AthAt5g53530
GO:0005829 cytosol C
IDA
HsaVPS26A
SpoSPAC4G9.13c
ISS
HsaVPS26B
GO:0016020 membrane C
IDA
AthAt5g53530
GO:0030904 retromer complex C
IDA
AthAt5g53530
IMP
SceS000003589
SpoSPAC4G9.13c
IPI
SceS000003589
ISS
AthAt5g53530
SpoSPAC4G9.13c
GO:0030906 retromer complex, inner shell C
IMP
SceS000003589
GO:0003674 molecular_function F
ND
AthAt5g53530
At4g27690
GO:0005515 protein binding F
IPI
HsaVPS26A
GO:0008565 protein transporter activity F
IMP
SceS000003589
IPI
SceS000003589
NAS
HsaVPS26A
GO:0016787 hydrolase activity F
ISS
SpoSPAC4G9.13c
GO:0000003 reproduction P
IMP
CelWBGene00006931
GO:0006886 intracellular protein transport P
IMP
SpoSPAC4G9.13c
ISS
AthAt4g27690
At5g53530
RCA
SceS000003589
GO:0006914 autophagy P
RCA
SceS000003589
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000003589
GO:0008333 endosome to lysosome transport P
ISS
AthAt5g53530
GO:0015031 protein transport P
RCA
SceS000003589
GO:0030437 ascospore formation P
IMP
SpoSPAC4G9.13c
GO:0042147 retrograde transport, endosome to
Golgi		 P
IMP
SpoSPAC4G9.13c
IPI
SceS000003589
ISS
AthAt5g53530
At4g27690
NAS
HsaVPS26A
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000003589
GO:0045184 establishment of protein localization P
RCA
SceS000003589

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3601

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) VPS26B GI:16418381 Q4G0F5
Pan troglodytes (Ptr) VPS26B GI:114641369
Canis familiaris (Cfa) VPS26B GI:73954574
Mus musculus (Mmu) Vps26b
(MGI:1917656)		 GI:29825827 Q8C0E2
Rattus norvegicus (Rno) Vps26b GI:34866729
Gallus gallus (Gga) VPS26B GI:50760047
Caenorhabditis elegans (Cel) vps-26
(CE28684;
WBGene00006931)		 GI:17542452 O01258
Schizosaccharomyces pombe (Spo) pep8
(SPAC4G9.13c)		 GI:19114607 Q10243
Saccharomyces cerevisiae (Sce) PEP8
(S000003589)		 GI:6322408 P40335
Kluyveromyces lactis (Kla) KLLA0F01419g GI:50310249
Eremothecium gossypii (Ego) AGOS_AEL178C GI:45190429
Magnaporthe grisea (Mgr) MGG_04830 GI:39945694
Neurospora crassa (Ncr) NCU02743.1 GI:32423003


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC4G9.13c
GO:0005768 endosome C
IMP
SpoSPAC4G9.13c
IPI
SceS000003589
ISS
SpoSPAC4G9.13c
GO:0005829 cytosol C
IDA
SpoSPAC4G9.13c
ISS
HsaVPS26B
GO:0030904 retromer complex C
IMP
SceS000003589
SpoSPAC4G9.13c
IPI
SceS000003589
ISS
SpoSPAC4G9.13c
GO:0030906 retromer complex, inner shell C
IMP
SceS000003589
GO:0008565 protein transporter activity F
IMP
SceS000003589
IPI
SceS000003589
GO:0016787 hydrolase activity F
ISS
SpoSPAC4G9.13c
GO:0000003 reproduction P
IMP
CelWBGene00006931
GO:0006886 intracellular protein transport P
IMP
SpoSPAC4G9.13c
RCA
SceS000003589
GO:0006914 autophagy P
RCA
SceS000003589
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000003589
GO:0015031 protein transport P
RCA
SceS000003589
GO:0030437 ascospore formation P
IMP
SpoSPAC4G9.13c
GO:0042147 retrograde transport, endosome to
Golgi		 P
IMP
SpoSPAC4G9.13c
IPI
SceS000003589
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000003589
GO:0045184 establishment of protein localization P
RCA
SceS000003589

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1369

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1612 ENSANGP00000017705
Ashbya gossypii (Ago) ago2328 AEL178C
Arabidopsis thaliana (Ath) ath20786 At4g27690.1
Arabidopsis thaliana (Ath) ath27321 At5g53530.1
Caenorhabditis elegans (Cel) cel15800 T20D3.7
(CE28684;
WBGene00006931)
Candida glabrata (Cgl) cgl3206 CAGL0J04994g
Cryptococcus neoformans (Cne) cne485 163.m06299
Dictyostelium discoideum (Ddi) ddi11442 DDB0191205
Debaryomyces hansenii (Dha) dha556 DEHA0A12463g
Drosophila melanogaster (Dme) dme16124 CG14804-PA
(FBgn0014411)
Danio rerio (Dre) dre29000 ENSDARP00000005752
Danio rerio (Dre) dre6088 ENSDARP00000020396
(vps26b)		 Q7ZV03
Danio rerio (Dre) dre2034 ENSDARP00000047887
Takifugu rubripes (Fru) fru4298 SINFRUP00000130236
Takifugu rubripes (Fru) fru14171 SINFRUP00000132317
Takifugu rubripes (Fru) fru9904 SINFRUP00000153606
Gallus gallus (Gga) gga13161 ENSGALP00000002310
(VPS26B)
Gallus gallus (Gga) gga20344 ENSGALP00000006624
(VPS26A)
Homo sapiens (Hsa) hsa4013 ENSP00000263559
(VPS26A)		 O75436
Homo sapiens (Hsa) hsa6850 ENSP00000281187
(VPS26B)		 Q4G0F5
Kluyveromyces lactis (Kla) kla4143 KLLA0F01419g
Mus musculus (Mmu) mmu2244 ENSMUSP00000020272
(MGI:1353654)		 Q6PE78
Mus musculus (Mmu) mmu27243 ENSMUSP00000034470
(MGI:1917656)		 Q8C0E2-1
Neurospora crassa (Ncr) ncr2655 NCU02743.2
Oryza sativa (Osa) osa22580 3751.m00159
Plasmodium falciparum (Pfa) pfa5264 PFL2415w
Rattus norvegicus (Rno) rno17909 ENSRNOP00000039714
(RGD:1359254)
Rattus norvegicus (Rno) rno17908 ENSRNOP00000048336
(RGD:1359254)
Saccharomyces cerevisiae (Sce) sce3310 YJL053W
(S000003589)
Schizosaccharomyces pombe (Spo) spo757 SPAC4G9.13c Q10243
Yarrowia lipolytica (Yli) yli3701 YALI0D23793g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC4G9.13c
GO:0005768 endosome C
IDA
MmuMGI:1353654
IMP
SpoSPAC4G9.13c
IPI
SceS000003589
ISS
SpoSPAC4G9.13c
GO:0005771 multivesicular body C
IDA
AthAt5g53530
GO:0005792 microsome C
IDA
AthAt5g53530
GO:0005829 cytosol C
IDA
SpoSPAC4G9.13c
GO:0016020 membrane C
IDA
AthAt5g53530
GO:0030904 retromer complex C
IDA
AthAt5g53530
IMP
SceS000003589
SpoSPAC4G9.13c
IPI
SceS000003589
ISS
AthAt5g53530
SpoSPAC4G9.13c
GO:0030906 retromer complex, inner shell C
IMP
SceS000003589
GO:0003674 molecular_function F
ND
AthAt5g53530
At4g27690
PfaPFL2415w
GO:0005515 protein binding F
IPI
MmuMGI:1353654
GO:0008565 protein transporter activity F
IMP
SceS000003589
IPI
SceS000003589
GO:0016787 hydrolase activity F
ISS
SpoSPAC4G9.13c
GO:0000003 reproduction P
IMP
CelWBGene00006931
GO:0006605 protein targeting P
ISS
DmeFBgn0014411
GO:0006886 intracellular protein transport P
IMP
SpoSPAC4G9.13c
ISS
AthAt4g27690
At5g53530
DmeFBgn0014411
RCA
SceS000003589
GO:0006914 autophagy P
RCA
SceS000003589
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000003589
GO:0007040 lysosome organization P
ISS
DmeFBgn0014411
GO:0008333 endosome to lysosome transport P
ISS
AthAt5g53530
GO:0015031 protein transport P
RCA
SceS000003589
GO:0030437 ascospore formation P
IMP
SpoSPAC4G9.13c
GO:0042147 retrograde transport, endosome to
Golgi		 P
IDA
MmuMGI:1353654
IMP
SpoSPAC4G9.13c
IPI
SceS000003589
ISS
AthAt5g53530
At4g27690
TAS
PfaPFL2415w
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000003589
GO:0045184 establishment of protein localization P
RCA
SceS000003589

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC4G9.13c
(Q10243)		 YJL053W
(S000003589)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC4G9.13c
GO:0005768 endosome C
IMP
SpoSPAC4G9.13c
IPI
SceS000003589
ISS
SpoSPAC4G9.13c
GO:0005829 cytosol C
IDA
SpoSPAC4G9.13c
GO:0030904 retromer complex C
IMP
SceS000003589
SpoSPAC4G9.13c
IPI
SceS000003589
ISS
SpoSPAC4G9.13c
GO:0030906 retromer complex, inner shell C
IMP
SceS000003589
GO:0008565 protein transporter activity F
IMP
SceS000003589
IPI
SceS000003589
GO:0016787 hydrolase activity F
ISS
SpoSPAC4G9.13c
GO:0006886 intracellular protein transport P
IMP
SpoSPAC4G9.13c
RCA
SceS000003589
GO:0006914 autophagy P
RCA
SceS000003589
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000003589
GO:0015031 protein transport P
RCA
SceS000003589
GO:0030437 ascospore formation P
IMP
SpoSPAC4G9.13c
GO:0042147 retrograde transport, endosome to
Golgi		 P
IMP
SpoSPAC4G9.13c
IPI
SceS000003589
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000003589
GO:0045184 establishment of protein localization P
RCA
SceS000003589

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk