YOGY Home YOGY Help

Search term: YJL090C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DPB11
SGD link S000003626
Alternative ID YJL090C
Description Replication initiation protein that loads DNA pol epsilon onto pre-replication complexes at origins; checkpoint sensor recruited to stalled replication forks by the checkpoint clamp complex where it activates Mec1p; ortholog of human TopBP1
Synonyms YJL090C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1929 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Nucleotide excision repair factor NEF2, RAD4/CUT5 component

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g77320 GI:15223895
Arabidopsis thaliana (Ath) At4g02110 GI:15235233
Caenorhabditis elegans (Cel) CE05818 GI:17507231
Drosophila melanogaster (Dme) 7292915
(FBgn0002878)		 GI:17864586 Q9VY97
Homo sapiens (Hsa) Hs20545800 GI:20545800
Homo sapiens (Hsa) Hs5902138 GI:5902138
Saccharomyces cerevisiae (Sce) YJL090c
(S000003626)		 GI:6322371 P47027
Schizosaccharomyces pombe (Spo) SPAC23C4.18c GI:19114102 P32372
Encephalitozoon cuniculi (Ecu) ECU02g1320 GI:19074051 Q8SWA0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
ISS
AthAt4g02110
At1g77320
GO:0005634 nucleus C
IDA
SpoSPAC23C4.18c
GO:0005657 replication fork C
IDA
SceS000003626
TAS
SceS000003626
GO:0005816 spindle pole body C
IDA
SpoSPAC23C4.18c
GO:0005819 spindle C
IDA
SpoSPAC23C4.18c
GO:0005829 cytosol C
IDA
SpoSPAC23C4.18c
GO:0008622 epsilon DNA polymerase complex C
IDA
SceS000003626
GO:0031261 DNA replication preinitiation complex C
IMP
SceS000003626
ISS
SpoSPAC23C4.18c
GO:0043596 nuclear replication fork C
ISS
SpoSPAC23C4.18c
GO:0003713 transcription coactivator activity F
ISS
AthAt4g02110
At1g77320
GO:0005515 protein binding F
IPI
SceS000003626
SpoSPAC23C4.18c
GO:0030295 protein kinase activator activity F
IDA
SceS000003626
GO:0000076 DNA replication checkpoint P
IMP
SceS000003626
TAS
SpoSPAC23C4.18c
GO:0000077 DNA damage checkpoint P
IMP
SpoSPAC23C4.18c
GO:0000725 recombinational repair P
IDA
SceS000003626
IGI
SceS000003626
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000003626
GO:0001934 positive regulation of protein amino acid
phosphorylation		 P
IDA
SceS000003626
GO:0006270 DNA-dependent DNA replication initiation P
ISS
SpoSPAC23C4.18c
TAS
SceS000003626
GO:0006272 leading strand elongation P
TAS
SceS000003626
GO:0006273 lagging strand elongation P
TAS
SceS000003626
GO:0006289 nucleotide-excision repair P
TAS
SceS000003626
GO:0006298 mismatch repair P
NAS
SceS000003626
GO:0006974 response to DNA damage stimulus P
ISS
AthAt1g77320
GO:0007067 mitosis P
TAS
DmeFBgn0002878
GO:0007095 mitotic cell cycle G2/M transition DNA damage
checkpoint		 P
IGI
SceS000003626
GO:0007131 reciprocal meiotic recombination P
TAS
AthAt1g77320
GO:0007140 male meiosis P
IMP
AthAt1g77320
GO:0007143 female meiosis P
IMP
AthAt1g77320
GO:0008150 biological_process P
ND
AthAt4g02110
GO:0031574 S-M checkpoint P
IMP
SpoSPAC23C4.18c
GO:0048477 oogenesis P
TAS
DmeFBgn0002878
GO:0071163 DNA replication preinitiation complex
assembly		 P
IMP
SpoSPAC23C4.18c

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117841

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) DPB11
(S000003626)		 GI:6322371 P47027
Kluyveromyces lactis (Kla) KLLA0F14300g GI:50311395
Eremothecium gossypii (Ego) AGOS_AFR095C GI:45198613


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005657 replication fork C
IDA
SceS000003626
TAS
SceS000003626
GO:0008622 epsilon DNA polymerase complex C
IDA
SceS000003626
GO:0031261 DNA replication preinitiation complex C
IMP
SceS000003626
GO:0005515 protein binding F
IPI
SceS000003626
GO:0030295 protein kinase activator activity F
IDA
SceS000003626
GO:0000076 DNA replication checkpoint P
IMP
SceS000003626
GO:0000725 recombinational repair P
IDA
SceS000003626
IGI
SceS000003626
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000003626
GO:0001934 positive regulation of protein amino acid
phosphorylation		 P
IDA
SceS000003626
GO:0006270 DNA-dependent DNA replication initiation P
TAS
SceS000003626
GO:0006272 leading strand elongation P
TAS
SceS000003626
GO:0006273 lagging strand elongation P
TAS
SceS000003626
GO:0006289 nucleotide-excision repair P
TAS
SceS000003626
GO:0006298 mismatch repair P
NAS
SceS000003626
GO:0007095 mitotic cell cycle G2/M transition DNA damage
checkpoint		 P
IGI
SceS000003626

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_15201

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3287 AFR095C
Candida glabrata (Cgl) cgl4225 CAGL0L03410g
Debaryomyces hansenii (Dha) dha2431 DEHA0D03047g
Kluyveromyces lactis (Kla) kla4722 KLLA0F14300g
Neurospora crassa (Ncr) ncr9253 NCU09503.2
Saccharomyces cerevisiae (Sce) sce3350 YJL090C
(S000003626)
Schizosaccharomyces pombe (Spo) spo3121 SPAC23C4.18c P32372
Yarrowia lipolytica (Yli) yli4769 YALI0E21978g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC23C4.18c
GO:0005657 replication fork C
IDA
SceS000003626
TAS
SceS000003626
GO:0005816 spindle pole body C
IDA
SpoSPAC23C4.18c
GO:0005819 spindle C
IDA
SpoSPAC23C4.18c
GO:0005829 cytosol C
IDA
SpoSPAC23C4.18c
GO:0008622 epsilon DNA polymerase complex C
IDA
SceS000003626
GO:0031261 DNA replication preinitiation complex C
IMP
SceS000003626
ISS
SpoSPAC23C4.18c
GO:0043596 nuclear replication fork C
ISS
SpoSPAC23C4.18c
GO:0005515 protein binding F
IPI
SceS000003626
SpoSPAC23C4.18c
GO:0030295 protein kinase activator activity F
IDA
SceS000003626
GO:0000076 DNA replication checkpoint P
IMP
SceS000003626
TAS
SpoSPAC23C4.18c
GO:0000077 DNA damage checkpoint P
IMP
SpoSPAC23C4.18c
GO:0000725 recombinational repair P
IDA
SceS000003626
IGI
SceS000003626
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000003626
GO:0001934 positive regulation of protein amino acid
phosphorylation		 P
IDA
SceS000003626
GO:0006270 DNA-dependent DNA replication initiation P
ISS
SpoSPAC23C4.18c
TAS
SceS000003626
GO:0006272 leading strand elongation P
TAS
SceS000003626
GO:0006273 lagging strand elongation P
TAS
SceS000003626
GO:0006289 nucleotide-excision repair P
TAS
SceS000003626
GO:0006298 mismatch repair P
NAS
SceS000003626
GO:0007095 mitotic cell cycle G2/M transition DNA damage
checkpoint		 P
IGI
SceS000003626
GO:0031574 S-M checkpoint P
IMP
SpoSPAC23C4.18c
GO:0071163 DNA replication preinitiation complex
assembly		 P
IMP
SpoSPAC23C4.18c

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC23C4.18c
(P32372)		 YJL090C
(S000003626)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC23C4.18c
GO:0005657 replication fork C
IDA
SceS000003626
TAS
SceS000003626
GO:0005816 spindle pole body C
IDA
SpoSPAC23C4.18c
GO:0005819 spindle C
IDA
SpoSPAC23C4.18c
GO:0005829 cytosol C
IDA
SpoSPAC23C4.18c
GO:0008622 epsilon DNA polymerase complex C
IDA
SceS000003626
GO:0031261 DNA replication preinitiation complex C
IMP
SceS000003626
ISS
SpoSPAC23C4.18c
GO:0043596 nuclear replication fork C
ISS
SpoSPAC23C4.18c
GO:0005515 protein binding F
IPI
SceS000003626
SpoSPAC23C4.18c
GO:0030295 protein kinase activator activity F
IDA
SceS000003626
GO:0000076 DNA replication checkpoint P
IMP
SceS000003626
TAS
SpoSPAC23C4.18c
GO:0000077 DNA damage checkpoint P
IMP
SpoSPAC23C4.18c
GO:0000725 recombinational repair P
IDA
SceS000003626
IGI
SceS000003626
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000003626
GO:0001934 positive regulation of protein amino acid
phosphorylation		 P
IDA
SceS000003626
GO:0006270 DNA-dependent DNA replication initiation P
ISS
SpoSPAC23C4.18c
TAS
SceS000003626
GO:0006272 leading strand elongation P
TAS
SceS000003626
GO:0006273 lagging strand elongation P
TAS
SceS000003626
GO:0006289 nucleotide-excision repair P
TAS
SceS000003626
GO:0006298 mismatch repair P
NAS
SceS000003626
GO:0007095 mitotic cell cycle G2/M transition DNA damage
checkpoint		 P
IGI
SceS000003626
GO:0031574 S-M checkpoint P
IMP
SpoSPAC23C4.18c
GO:0071163 DNA replication preinitiation complex
assembly		 P
IMP
SpoSPAC23C4.18c

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk