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Search term: YJL115W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ASF1
SGD link S000003651
Alternative ID YJL115W
Description Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition
Synonyms YJL115W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3265 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING Histone chaperone involved in gene silencing

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g66740 GI:15219729
Arabidopsis thaliana (Ath) At5g38110 GI:15240842
Caenorhabditis elegans (Cel) CE02627 GI:17533089
Caenorhabditis elegans (Cel) CE15579 GI:17505454
Drosophila melanogaster (Dme) 7293763
(FBgn0029094)		 GI:17737649
Homo sapiens (Hsa) Hs7661592
(ASF1A)		 GI:7661592 Q9Y294
Homo sapiens (Hsa) Hs8922549
(ASF1B)		 GI:8922549 Q9NVP2
Homo sapiens (Hsa) Hs20551802 GI:20551802
Saccharomyces cerevisiae (Sce) YJL115w
(S000003651)		 GI:6322346 P32447
Schizosaccharomyces pombe (Spo) SPCC663.05c GI:19075767 O74515
Encephalitozoon cuniculi (Ecu) ECU07g0130 GI:19074435 Q8SRM1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
NAS
SpoSPCC663.05c
GO:0005634 nucleus C
IDA
HsaASF1A
SpoSPCC663.05c
NAS
HsaASF1A
GO:0005678 chromatin assembly complex C
IDA
SceS000003651
SpoSPCC663.05c
ISS
DmeFBgn0029094
GO:0016585 chromatin remodeling complex C
IDA
HsaASF1A
GO:0035059 RCAF complex C
IDA
DmeFBgn0029094
GO:0003674 molecular_function F
ND
AthAt5g38110
At1g66740
GO:0003682 chromatin binding F
NAS
HsaASF1A
GO:0005515 protein binding F
IPI
DmeFBgn0029094
HsaASF1B
SpoSPCC663.05c
GO:0030528 transcription regulator activity F
ISS
SpoSPCC663.05c
GO:0042393 histone binding F
IDA
HsaASF1A
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process		 P
ISS
AthAt1g66740
At5g38110
GO:0006260 DNA replication P
RCA
SceS000003651
GO:0006281 DNA repair P
IDA
HsaASF1A
RCA
SceS000003651
GO:0006323 DNA packaging P
RCA
SceS000003651
GO:0006325 chromatin organization P
IDA
DmeFBgn0029094
IGI
DmeFBgn0029094
GO:0006334 nucleosome assembly P
IDA
HsaASF1A
IMP
DmeFBgn0029094
GO:0006335 DNA replication-dependent nucleosome
assembly		 P
IDA
SceS000003651
ISS
SpoSPCC663.05c
GO:0006336 DNA replication-independent nucleosome
assembly		 P
IDA
SceS000003651
ISS
SpoSPCC663.05c
GO:0006337 nucleosome disassembly P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0006342 chromatin silencing P
ISS
SpoSPCC663.05c
GO:0006345 loss of chromatin silencing P
NAS
HsaASF1A
GO:0006348 chromatin silencing at telomere P
IGI
SceS000003651
GO:0006974 response to DNA damage stimulus P
RCA
SceS000003651
GO:0007517 muscle organ development P
IMP
DmeFBgn0029094
GO:0009294 DNA mediated transformation P
IMP
AthAt5g38110
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000003651
GO:0016458 gene silencing P
RCA
SceS000003651
GO:0016481 negative regulation of transcription P
RCA
SceS000003651
GO:0016573 histone acetylation P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000003651
GO:0035066 positive regulation of histone
acetylation		 P
IDA
SceS000003651
IGI
SceS000003651
IMP
SceS000003651
IPI
SceS000003651
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000003651
GO:0043486 histone exchange P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IMP
SceS000003651
GO:0048024 regulation of nuclear mRNA splicing, via
spliceosome		 P
IMP
DmeFBgn0029094
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0029094
GO:0051276 chromosome organization P
RCA
SceS000003651
GO:0051726 regulation of cell cycle P
IMP
DmeFBgn0029094

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
8528

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ASF1A GI:7661592 Q9Y294
Canis familiaris (Cfa) ASF1A GI:57031837
Mus musculus (Mmu) Asf1a
(MGI:1913653)		 GI:13384964 Q9CQE6
Rattus norvegicus (Rno) Asf1a GI:27705326
Gallus gallus (Gga) ASF1A GI:113206164
Drosophila melanogaster (Dme) asf1
(FBgn0029094)		 GI:17737649
Anopheles gambiae (Aga) AgaP_AGAP005920 GI:158295000
Caenorhabditis elegans (Cel) unc-85 GI:115533863
Caenorhabditis elegans (Cel) asfl-1
(CE36095;
WBGene00007277)		 GI:71980526
Schizosaccharomyces pombe (Spo) cia1
(SPCC663.05c)		 GI:19075767 O74515
Saccharomyces cerevisiae (Sce) ASF1
(S000003651)		 GI:6322346 P32447
Kluyveromyces lactis (Kla) KLLA0E14938g GI:50309227
Eremothecium gossypii (Ego) AGOS_ADR320C GI:45188193
Magnaporthe grisea (Mgr) MGG_14445 GI:145601910
Neurospora crassa (Ncr) NCU09436.1 GI:32423381
Arabidopsis thaliana (Ath) ASF1B GI:15240842
Arabidopsis thaliana (Ath) SGA2 GI:15219729
Oryza sativa (Osa) Os05g0553800 GI:115465331
Plasmodium falciparum (Pfa) PFL1180w GI:124806152


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
NAS
SpoSPCC663.05c
GO:0005634 nucleus C
IDA
HsaASF1A
SpoSPCC663.05c
NAS
HsaASF1A
GO:0005678 chromatin assembly complex C
IDA
SceS000003651
SpoSPCC663.05c
ISS
DmeFBgn0029094
PfaPFL1180w
GO:0016585 chromatin remodeling complex C
IDA
HsaASF1A
ISO
MmuMGI:1913653
GO:0035059 RCAF complex C
IDA
DmeFBgn0029094
GO:0003674 molecular_function F
ND
AthSGA2
GO:0003682 chromatin binding F
ISS
PfaPFL1180w
NAS
HsaASF1A
GO:0005515 protein binding F
IPI
DmeFBgn0029094
HsaASF1B
SpoSPCC663.05c
GO:0030528 transcription regulator activity F
ISS
SpoSPCC663.05c
GO:0042393 histone binding F
IDA
HsaASF1A
IMP
SceS000003651
ISO
MmuMGI:1913653
ISS
SpoSPCC663.05c
GO:0051082 unfolded protein binding F
ISS
PfaPFL1180w
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process		 P
ISS
AthSGA2
GO:0006260 DNA replication P
RCA
SceS000003651
GO:0006281 DNA repair P
IDA
HsaASF1A
ISO
MmuMGI:1913653
RCA
SceS000003651
GO:0006323 DNA packaging P
RCA
SceS000003651
GO:0006325 chromatin organization P
IDA
DmeFBgn0029094
IGI
DmeFBgn0029094
GO:0006334 nucleosome assembly P
IDA
HsaASF1A
IMP
DmeFBgn0029094
ISO
MmuMGI:1913653
GO:0006335 DNA replication-dependent nucleosome
assembly		 P
IDA
SceS000003651
ISS
SpoSPCC663.05c
GO:0006336 DNA replication-independent nucleosome
assembly		 P
IDA
SceS000003651
ISS
SpoSPCC663.05c
GO:0006337 nucleosome disassembly P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0006342 chromatin silencing P
ISS
SpoSPCC663.05c
GO:0006345 loss of chromatin silencing P
NAS
HsaASF1A
GO:0006348 chromatin silencing at telomere P
IGI
SceS000003651
GO:0006974 response to DNA damage stimulus P
RCA
SceS000003651
GO:0007517 muscle organ development P
IMP
DmeFBgn0029094
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000003651
GO:0016458 gene silencing P
ISS
PfaPFL1180w
RCA
SceS000003651
GO:0016481 negative regulation of transcription P
RCA
SceS000003651
GO:0016573 histone acetylation P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000003651
GO:0035066 positive regulation of histone
acetylation		 P
IDA
SceS000003651
IGI
SceS000003651
IMP
SceS000003651
IPI
SceS000003651
GO:0040011 locomotion P
IMP
CelWBGene00007277
GO:0040027 negative regulation of vulval development P
IMP
CelWBGene00007277
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000003651
GO:0043486 histone exchange P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IMP
SceS000003651
GO:0048024 regulation of nuclear mRNA splicing, via
spliceosome		 P
IMP
DmeFBgn0029094
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0029094
GO:0051276 chromosome organization P
RCA
SceS000003651
GO:0051726 regulation of cell cycle P
IMP
DmeFBgn0029094

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1558

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1362 ENSANGP00000013594
Ashbya gossypii (Ago) ago2061 ADR320C
Arabidopsis thaliana (Ath) ath5904 At1g66740.1
Arabidopsis thaliana (Ath) ath25570 At5g38110.1
Caenorhabditis elegans (Cel) cel928 C03D6.5
(CE36095;
WBGene00007277)
Caenorhabditis elegans (Cel) cel5964 F10G7.3
(CE39722;
WBGene00017368)
Candida glabrata (Cgl) cgl4314 CAGL0L05412g
Cryptococcus neoformans (Cne) cne1886 181.m07854
Dictyostelium discoideum (Ddi) ddi8703 DDB0186540
Debaryomyces hansenii (Dha) dha466 DEHA0A10450g
Drosophila melanogaster (Dme) dme10251 CG9383-PA
(FBgn0029094)
Danio rerio (Dre) dre17208 ENSDARP00000025843
(asf1b)		 Q6NYY4
Encephalitozoon cuniculi (Ecu) ecu1821 19074435
Takifugu rubripes (Fru) fru21785 SINFRUP00000135588
Takifugu rubripes (Fru) fru11898 SINFRUP00000158342
Gallus gallus (Gga) gga15501 ENSGALP00000023972
(ASF1A)
Homo sapiens (Hsa) hsa27676 ENSP00000229595
(ASF1A)		 Q9Y294
Homo sapiens (Hsa) hsa15781 ENSP00000263382
(ASF1B)		 Q9NVP2
Kluyveromyces lactis (Kla) kla3619 KLLA0E14938g
Mus musculus (Mmu) mmu26295 ENSMUSP00000005607
(MGI:1914179)		 Q9DAP7
Mus musculus (Mmu) mmu2148 ENSMUSP00000020004
(MGI:1913653)		 Q9CQE6
Neurospora crassa (Ncr) ncr9192 NCU09436.2
Oryza sativa (Osa) osa14919 2977.m00154
Plasmodium falciparum (Pfa) pfa5019 PFL1180w
Rattus norvegicus (Rno) rno17940 ENSRNOP00000000471
(RGD:1311941)
Rattus norvegicus (Rno) rno14788 ENSRNOP00000006964
(RGD:1304918)		 B0BN69
Saccharomyces cerevisiae (Sce) sce3375 YJL115W
(S000003651)
Schizosaccharomyces pombe (Spo) spo1028 SPCC663.05c O74515
Yarrowia lipolytica (Yli) yli47 YALI0A01375g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
MmuMGI:1914179
GO:0000790 nuclear chromatin C
NAS
SpoSPCC663.05c
GO:0005634 nucleus C
IDA
SpoSPCC663.05c
GO:0005678 chromatin assembly complex C
IDA
SceS000003651
SpoSPCC663.05c
ISS
DmeFBgn0029094
PfaPFL1180w
GO:0016585 chromatin remodeling complex C
ISO
MmuMGI:1913653
GO:0035059 RCAF complex C
IDA
DmeFBgn0029094
GO:0003674 molecular_function F
ND
AthAt5g38110
At1g66740
GO:0003682 chromatin binding F
ISS
PfaPFL1180w
GO:0005515 protein binding F
IPI
DmeFBgn0029094
SpoSPCC663.05c
GO:0030528 transcription regulator activity F
ISS
SpoSPCC663.05c
GO:0042393 histone binding F
IDA
MmuMGI:1914179
IMP
SceS000003651
ISO
MmuMGI:1913653
ISS
SpoSPCC663.05c
GO:0051082 unfolded protein binding F
ISS
PfaPFL1180w
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process		 P
ISS
AthAt1g66740
At5g38110
GO:0006260 DNA replication P
RCA
SceS000003651
GO:0006281 DNA repair P
ISO
MmuMGI:1913653
RCA
SceS000003651
GO:0006323 DNA packaging P
RCA
SceS000003651
GO:0006325 chromatin organization P
IDA
DmeFBgn0029094
IGI
DmeFBgn0029094
GO:0006334 nucleosome assembly P
IDA
MmuMGI:1914179
IMP
DmeFBgn0029094
ISO
MmuMGI:1913653
GO:0006335 DNA replication-dependent nucleosome
assembly		 P
IDA
SceS000003651
ISS
SpoSPCC663.05c
GO:0006336 DNA replication-independent nucleosome
assembly		 P
IDA
SceS000003651
ISS
SpoSPCC663.05c
GO:0006337 nucleosome disassembly P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0006342 chromatin silencing P
ISS
SpoSPCC663.05c
GO:0006348 chromatin silencing at telomere P
IGI
SceS000003651
GO:0006974 response to DNA damage stimulus P
RCA
SceS000003651
GO:0007517 muscle organ development P
IMP
DmeFBgn0029094
GO:0009294 DNA mediated transformation P
IMP
AthAt5g38110
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000003651
GO:0016458 gene silencing P
ISS
PfaPFL1180w
RCA
SceS000003651
GO:0016481 negative regulation of transcription P
RCA
SceS000003651
GO:0016573 histone acetylation P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000003651
GO:0035066 positive regulation of histone
acetylation		 P
IDA
SceS000003651
IGI
SceS000003651
IMP
SceS000003651
IPI
SceS000003651
GO:0040011 locomotion P
IMP
CelWBGene00007277
GO:0040027 negative regulation of vulval development P
IMP
CelWBGene00007277
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000003651
GO:0043486 histone exchange P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IMP
SceS000003651
GO:0048024 regulation of nuclear mRNA splicing, via
spliceosome		 P
IMP
DmeFBgn0029094
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0029094
GO:0051276 chromosome organization P
RCA
SceS000003651
GO:0051726 regulation of cell cycle P
IMP
DmeFBgn0029094

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC663.05c
(O74515)		 YJL115W
(S000003651)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
NAS
SpoSPCC663.05c
GO:0005634 nucleus C
IDA
SpoSPCC663.05c
GO:0005678 chromatin assembly complex C
IDA
SceS000003651
SpoSPCC663.05c
GO:0005515 protein binding F
IPI
SpoSPCC663.05c
GO:0030528 transcription regulator activity F
ISS
SpoSPCC663.05c
GO:0042393 histone binding F
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0006260 DNA replication P
RCA
SceS000003651
GO:0006281 DNA repair P
RCA
SceS000003651
GO:0006323 DNA packaging P
RCA
SceS000003651
GO:0006335 DNA replication-dependent nucleosome
assembly		 P
IDA
SceS000003651
ISS
SpoSPCC663.05c
GO:0006336 DNA replication-independent nucleosome
assembly		 P
IDA
SceS000003651
ISS
SpoSPCC663.05c
GO:0006337 nucleosome disassembly P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0006342 chromatin silencing P
ISS
SpoSPCC663.05c
GO:0006348 chromatin silencing at telomere P
IGI
SceS000003651
GO:0006974 response to DNA damage stimulus P
RCA
SceS000003651
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000003651
GO:0016458 gene silencing P
RCA
SceS000003651
GO:0016481 negative regulation of transcription P
RCA
SceS000003651
GO:0016573 histone acetylation P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000003651
GO:0035066 positive regulation of histone
acetylation		 P
IDA
SceS000003651
IGI
SceS000003651
IMP
SceS000003651
IPI
SceS000003651
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000003651
GO:0043486 histone exchange P
IMP
SceS000003651
ISS
SpoSPCC663.05c
GO:0043618 regulation of transcription from RNA polymerase II
promoter in response to stress		 P
IMP
SceS000003651
GO:0051276 chromosome organization P
RCA
SceS000003651

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Query species:

Include wild-cards:   

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GO info in one table:

s.khadayate@ucl.ac.uk