Search term: YJL164C

Gene summary:

KOG results:

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG0616	ACDHYPE

KOGs classification	KOGs description
CELLULAR PROCESSES AND SIGNALING	cAMP-dependent protein kinase catalytic subunit (PKA)

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At2g20040	GI:15225287
Caenorhabditis elegans (Cel)	CE04603	GI:17567857
Caenorhabditis elegans (Cel)	CE15473 (WBGene00002189)	GI:17508227	P21137
Caenorhabditis elegans (Cel)	CE15475	GI:17508225	P21137
Caenorhabditis elegans (Cel)	CE27166 (WBGene00018569)	GI:17567859	Q95ZT2
Drosophila melanogaster (Dme)	7297542	GI:17136902
Drosophila melanogaster (Dme)	7301971	GI:7301971
Drosophila melanogaster (Dme)	7301972	GI:17864122
Homo sapiens (Hsa)	Hs10835065	GI:10835065	O43930
Homo sapiens (Hsa)	Hs4826948 (PRKX)	GI:4826948	P51817
Homo sapiens (Hsa)	Hs15619015 (PRKACG)	GI:15619015	P22612
Homo sapiens (Hsa)	Hs4506055 (PRKACA)	GI:4506055	P17612
Homo sapiens (Hsa)	Hs4506057	GI:4506057	P22694
Saccharomyces cerevisiae (Sce)	YJL164c (S000003700)	GI:6322297
Saccharomyces cerevisiae (Sce)	YKL166c (S000001649)	GI:6322682	P05986
Saccharomyces cerevisiae (Sce)	YPL203w (S000006124)	GI:6325053	P06245
Schizosaccharomyces pombe (Spo)	SPBC106.10	GI:19111951	P40376
Encephalitozoon cuniculi (Ecu)	ECU07g0520	GI:19074474	Q8SRK8
Arabidopsis thaliana (Ath)	At2g20040	GI:15225287
Caenorhabditis elegans (Cel)	CE04603	GI:17567857
Caenorhabditis elegans (Cel)	CE15473 (WBGene00002189)	GI:17508227	P21137
Caenorhabditis elegans (Cel)	CE15475	GI:17508225	P21137
Caenorhabditis elegans (Cel)	CE27166 (WBGene00018569)	GI:17567859	Q95ZT2
Drosophila melanogaster (Dme)	7297542	GI:17136902
Drosophila melanogaster (Dme)	7301971	GI:7301971
Drosophila melanogaster (Dme)	7301972	GI:17864122
Homo sapiens (Hsa)	Hs10835065	GI:10835065	O43930
Homo sapiens (Hsa)	Hs4826948 (PRKX)	GI:4826948	P51817
Homo sapiens (Hsa)	Hs15619015 (PRKACG)	GI:15619015	P22612
Homo sapiens (Hsa)	Hs4506055 (PRKACA)	GI:4506055	P17612
Homo sapiens (Hsa)	Hs4506057	GI:4506057	P22694
Saccharomyces cerevisiae (Sce)	YJL164c (S000003700)	GI:6322297
Saccharomyces cerevisiae (Sce)	YKL166c (S000001649)	GI:6322682	P05986
Saccharomyces cerevisiae (Sce)	YPL203w (S000006124)	GI:6325053	P06245
Schizosaccharomyces pombe (Spo)	SPBC106.10	GI:19111951	P40376
Encephalitozoon cuniculi (Ecu)	ECU07g0520	GI:19074474	Q8SRK8

GO terms for KOG results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005624	membrane fraction	C	IDA Hsa PRKACA
GO:0005634	nucleus	C	IDA Sce S000003700 S000006124 S000001649 Spo SPBC106.10
GO:0005737	cytoplasm	C	IDA Sce S000003700 S000001649 Spo SPBC106.10
GO:0005829	cytosol	C	EXP Hsa PRKACG PRKACA IDA Spo SPBC106.10
GO:0005952	cAMP-dependent protein kinase complex	C	IDA Sce S000006124 S000003700 IGI Sce S000003700 S000006124 S000001649 IPI Sce S000003700 S000006124 NAS Hsa PRKACA TAS Spo SPBC106.10
GO:0004691	cAMP-dependent protein kinase activity	F	IDA Sce S000003700 S000006124 S000001649 IGI Sce S000003700 S000006124 S000001649 Spo SPBC106.10 IMP Sce S000003700 S000001649 ISS Sce S000006124 NAS Hsa PRKACA TAS Hsa PRKX
GO:0004857	enzyme inhibitor activity	F	RCA Sce S000001649
GO:0004862	cAMP-dependent protein kinase inhibitor activity	F	EXP Hsa PRKACA
GO:0005515	protein binding	F	IPI Hsa PRKACA Spo SPBC106.10
GO:0005524	ATP binding	F	ISS Spo SPBC106.10 NAS Hsa PRKACA
GO:0019901	protein kinase binding	F	IPI Hsa PRKACA
GO:0030234	enzyme regulator activity	F	RCA Sce S000001649
GO:0001300	chronological cell aging	P	IGI Spo SPBC106.10
GO:0001315	age-dependent response to reactive oxygen species	P	IGI Spo SPBC106.10 IMP Spo SPBC106.10
GO:0001403	invasive growth in response to glucose limitation	P	IMP Sce S000006124
GO:0002009	morphogenesis of an epithelium	P	IMP Cel WBGene00002189
GO:0002119	nematode larval development	P	IMP Cel WBGene00002189
GO:0006110	regulation of glycolysis	P	NAS Spo SPBC106.10
GO:0006112	energy reserve metabolic process	P	RCA Sce S000003700
GO:0006468	protein amino acid phosphorylation	P	IC Spo SPBC106.10 IDA Sce S000003700 S000006124 S000001649 IMP Sce S000003700 S000001649 NAS Hsa PRKACA
GO:0006914	autophagy	P	RCA Sce S000003700
GO:0006995	cellular response to nitrogen starvation	P	IMP Spo SPBC106.10
GO:0007005	mitochondrion organization	P	IGI Sce S000001649 IMP Sce S000001649
GO:0007039	vacuolar protein catabolic process	P	RCA Sce S000003700
GO:0007124	pseudohyphal growth	P	RCA Sce S000006124
GO:0007243	intracellular protein kinase cascade	P	EXP Hsa PRKACA PRKACG
GO:0007265	Ras protein signal transduction	P	IGI Sce S000003700 S000001649 S000006124 IMP Sce S000003700 ISS Sce S000006124 S000001649
GO:0007283	spermatogenesis	P	TAS Hsa PRKACG
GO:0007568	aging	P	RCA Sce S000006124 S000003700
GO:0008584	male gonad development	P	TAS Hsa PRKACG
GO:0009755	hormone-mediated signaling pathway	P	EXP Hsa PRKACA PRKACG
GO:0016049	cell growth	P	RCA Sce S000006124
GO:0018991	oviposition	P	IMP Cel WBGene00002189
GO:0019933	cAMP-mediated signaling	P	IC Spo SPBC106.10
GO:0030435	sporulation resulting in formation of a cellular spore	P	RCA Sce S000003700
GO:0031138	negative regulation of conjugation with cellular fusion	P	IMP Spo SPBC106.10
GO:0031142	induction of conjugation upon nitrogen starvation	P	IMP Spo SPBC106.10
GO:0034199	activation of protein kinase A activity	P	EXP Hsa PRKACA PRKACG
GO:0045014	negative regulation of transcription by glucose	P	IMP Spo SPBC106.10
GO:0050790	regulation of catalytic activity	P	RCA Sce S000003700 S000006124
GO:0061161	positive regulation of establishment of bipolar cell polarity resulting in cell shape	P	IMP Spo SPBC106.10

HomoloGene results:

HomoloGene cluster	Phylogenetic pattern
121574

Species	Gene ID	NCBI link	UniProt link
Homo sapiens (Hsa)	PRKACA	GI:4506055	P17612
Pan troglodytes (Ptr)	PRKACA	GI:114675717
Canis familiaris (Cfa)	PRKACA	GI:50978668
Mus musculus (Mmu)	Prkaca (MGI:97592)	GI:7110693	P05132
Rattus norvegicus (Rno)	Prkaca (RGD:3389)	GI:62665041	44373
Caenorhabditis elegans (Cel)	kin-1 (CE15473; WBGene00002189)	GI:17508227	P21137
Saccharomyces cerevisiae (Sce)	TPK1 (S000003700)	GI:6322297
Plasmodium falciparum (Pfa)	PFI1685w	GI:124507233

GO terms for Homologene results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005624	membrane fraction	C	IDA Hsa PRKACA ISO Mmu MGI:97592
GO:0005625	soluble fraction	C	ISO Mmu MGI:97592
GO:0005626	insoluble fraction	C	ISO Mmu MGI:97592
GO:0005634	nucleus	C	IDA Mmu MGI:97592 Sce S000003700 ISO Mmu MGI:97592
GO:0005654	nucleoplasm	C	EXP Mmu MGI:97592
GO:0005737	cytoplasm	C	IDA Mmu MGI:97592 Sce S000003700 ISO Mmu MGI:97592
GO:0005739	mitochondrion	C	IDA Mmu MGI:97592
GO:0005794	Golgi apparatus	C	ISO Mmu MGI:97592
GO:0005829	cytosol	C	EXP Hsa PRKACA Mmu MGI:97592
GO:0005886	plasma membrane	C	IDA Mmu MGI:97592
GO:0005952	cAMP-dependent protein kinase complex	C	IDA Sce S000003700 IGI Sce S000003700 IPI Sce S000003700 ISO Mmu MGI:97592 NAS Hsa PRKACA
GO:0031594	neuromuscular junction	C	IDA Mmu MGI:97592
GO:0043234	protein complex	C	ISO Mmu MGI:97592
GO:0048471	perinuclear region of cytoplasm	C	ISO Mmu MGI:97592
GO:0004672	protein kinase activity	F	IDA Mmu MGI:97592
GO:0004674	protein serine/threonine kinase activity	F	EXP Mmu MGI:97592
GO:0004691	cAMP-dependent protein kinase activity	F	EXP Mmu MGI:97592 IDA Sce S000003700 IGI Sce S000003700 IMP Sce S000003700 ISO Mmu MGI:97592 NAS Hsa PRKACA
GO:0004862	cAMP-dependent protein kinase inhibitor activity	F	EXP Hsa PRKACA
GO:0005515	protein binding	F	IPI Hsa PRKACA Mmu MGI:97592
GO:0005524	ATP binding	F	NAS Hsa PRKACA
GO:0019901	protein kinase binding	F	IPI Hsa PRKACA ISO Mmu MGI:97592
GO:0032403	protein complex binding	F	ISO Mmu MGI:97592
GO:0001707	mesoderm formation	P	IGI Mmu MGI:97592
GO:0002009	morphogenesis of an epithelium	P	IMP Cel WBGene00002189
GO:0002119	nematode larval development	P	IMP Cel WBGene00002189
GO:0006112	energy reserve metabolic process	P	RCA Sce S000003700
GO:0006468	protein amino acid phosphorylation	P	IDA Mmu MGI:97592 Sce S000003700 IMP Sce S000003700 ISO Mmu MGI:97592 NAS Hsa PRKACA
GO:0006914	autophagy	P	RCA Sce S000003700
GO:0007039	vacuolar protein catabolic process	P	RCA Sce S000003700
GO:0007243	intracellular protein kinase cascade	P	EXP Hsa PRKACA
GO:0007265	Ras protein signal transduction	P	IGI Sce S000003700 IMP Sce S000003700
GO:0007568	aging	P	RCA Sce S000003700
GO:0009755	hormone-mediated signaling pathway	P	EXP Hsa PRKACA
GO:0016310	phosphorylation	P	EXP Mmu MGI:97592
GO:0018105	peptidyl-serine phosphorylation	P	ISO Mmu MGI:97592
GO:0018991	oviposition	P	IMP Cel WBGene00002189
GO:0030435	sporulation resulting in formation of a cellular spore	P	RCA Sce S000003700
GO:0034199	activation of protein kinase A activity	P	EXP Hsa PRKACA
GO:0043457	regulation of cellular respiration	P	ISO Mmu MGI:97592
GO:0046777	protein amino acid autophosphorylation	P	IDA Mmu MGI:97592
GO:0046827	positive regulation of protein export from nucleus	P	IMP Mmu MGI:97592
GO:0050790	regulation of catalytic activity	P	RCA Sce S000003700
GO:0050804	regulation of synaptic transmission	P	IMP Mmu MGI:97592
GO:0051447	negative regulation of meiotic cell cycle	P	ISO Mmu MGI:97592
GO:0051966	regulation of synaptic transmission, glutamatergic	P	ISO Mmu MGI:97592
GO:0071374	cellular response to parathyroid hormone stimulus	P	IMP Mmu MGI:97592

OrthoMCL results:

OrthoMCL cluster	Phylogenetic pattern
OG1_70557

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Anopheles gambiae (Aga)	aga10021	ENSANGP00000011546
Saccharomyces cerevisiae (Sce)	sce3429	YJL164C (S000003700)

GO terms for OrthoMCL results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005634	nucleus	C	IDA Sce S000003700
GO:0005737	cytoplasm	C	IDA Sce S000003700
GO:0005952	cAMP-dependent protein kinase complex	C	IDA Sce S000003700 IGI Sce S000003700 IPI Sce S000003700
GO:0004691	cAMP-dependent protein kinase activity	F	IDA Sce S000003700 IGI Sce S000003700 IMP Sce S000003700
GO:0006112	energy reserve metabolic process	P	RCA Sce S000003700
GO:0006468	protein amino acid phosphorylation	P	IDA Sce S000003700 IMP Sce S000003700
GO:0006914	autophagy	P	RCA Sce S000003700
GO:0007039	vacuolar protein catabolic process	P	RCA Sce S000003700
GO:0007265	Ras protein signal transduction	P	IGI Sce S000003700 IMP Sce S000003700
GO:0007568	aging	P	RCA Sce S000003700
GO:0030435	sporulation resulting in formation of a cellular spore	P	RCA Sce S000003700
GO:0050790	regulation of catalytic activity	P	RCA Sce S000003700

Curated yeast ortholog results:

S. pombe systematic ID	S. cerevisiae systematic ID
SPBC106.10 (P40376)	YJL164C (S000003700)

GO terms for curated homolog results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005634	nucleus	C	IDA Sce S000003700 Spo SPBC106.10
GO:0005737	cytoplasm	C	IDA Sce S000003700 Spo SPBC106.10
GO:0005829	cytosol	C	IDA Spo SPBC106.10
GO:0005952	cAMP-dependent protein kinase complex	C	IDA Sce S000003700 IGI Sce S000003700 IPI Sce S000003700 TAS Spo SPBC106.10
GO:0004691	cAMP-dependent protein kinase activity	F	IDA Sce S000003700 IGI Sce S000003700 Spo SPBC106.10 IMP Sce S000003700
GO:0005515	protein binding	F	IPI Spo SPBC106.10
GO:0005524	ATP binding	F	ISS Spo SPBC106.10
GO:0001300	chronological cell aging	P	IGI Spo SPBC106.10
GO:0001315	age-dependent response to reactive oxygen species	P	IGI Spo SPBC106.10 IMP Spo SPBC106.10
GO:0006110	regulation of glycolysis	P	NAS Spo SPBC106.10
GO:0006112	energy reserve metabolic process	P	RCA Sce S000003700
GO:0006468	protein amino acid phosphorylation	P	IC Spo SPBC106.10 IDA Sce S000003700 IMP Sce S000003700
GO:0006914	autophagy	P	RCA Sce S000003700
GO:0006995	cellular response to nitrogen starvation	P	IMP Spo SPBC106.10
GO:0007039	vacuolar protein catabolic process	P	RCA Sce S000003700
GO:0007265	Ras protein signal transduction	P	IGI Sce S000003700 IMP Sce S000003700
GO:0007568	aging	P	RCA Sce S000003700
GO:0019933	cAMP-mediated signaling	P	IC Spo SPBC106.10
GO:0030435	sporulation resulting in formation of a cellular spore	P	RCA Sce S000003700
GO:0031138	negative regulation of conjugation with cellular fusion	P	IMP Spo SPBC106.10
GO:0031142	induction of conjugation upon nitrogen starvation	P	IMP Spo SPBC106.10
GO:0045014	negative regulation of transcription by glucose	P	IMP Spo SPBC106.10
GO:0050790	regulation of catalytic activity	P	RCA Sce S000003700
GO:0061161	positive regulation of establishment of bipolar cell polarity resulting in cell shape	P	IMP Spo SPBC106.10