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Search term: YJL167W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ERG20
SGD link S000003703
Alternative ID YJL167W
Description Farnesyl pyrophosphate synthetase, has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis
Synonyms YJL167W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0711 ACDHYPE

KOGs classification KOGs description
METABOLISM Polyprenyl synthetase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g17190 GI:15236002
Arabidopsis thaliana (Ath) At5g47770 GI:15238801
Caenorhabditis elegans (Cel) CE23901
(WBGene00011058)		 GI:17508563 O62336
Drosophila melanogaster (Dme) 7303618
(FBgn0025373)		 GI:17137582
Homo sapiens (Hsa) Hs4503685 GI:4503685 P14324
Homo sapiens (Hsa) Hs17440285 GI:17440285
Homo sapiens (Hsa) Hs17461852 GI:17461852
Homo sapiens (Hsa) Hs18584727 GI:18584727
Homo sapiens (Hsa) Hs22045197 GI:22045197
Saccharomyces cerevisiae (Sce) YJL167w
(S000003703)		 GI:6322294 P08524
Schizosaccharomyces pombe (Spo) SPAC6F12.13c GI:19114211 O14230
Schizosaccharomyces pombe (Spo) SPBC36.06c GI:19112126 O59703
Encephalitozoon cuniculi (Ecu) ECU11g1810 GI:19074981 Q8SQS0
Arabidopsis thaliana (Ath) At4g17190 GI:15236002
Arabidopsis thaliana (Ath) At5g47770 GI:15238801
Caenorhabditis elegans (Cel) CE23901
(WBGene00011058)		 GI:17508563 O62336
Drosophila melanogaster (Dme) 7303618
(FBgn0025373)		 GI:17137582
Homo sapiens (Hsa) Hs4503685 GI:4503685 P14324
Homo sapiens (Hsa) Hs17440285 GI:17440285
Homo sapiens (Hsa) Hs17461852 GI:17461852
Homo sapiens (Hsa) Hs18584727 GI:18584727
Homo sapiens (Hsa) Hs22045197 GI:22045197
Saccharomyces cerevisiae (Sce) YJL167w
(S000003703)		 GI:6322294 P08524
Schizosaccharomyces pombe (Spo) SPAC6F12.13c GI:19114211 O14230
Schizosaccharomyces pombe (Spo) SPBC36.06c GI:19112126 O59703
Encephalitozoon cuniculi (Ecu) ECU11g1810 GI:19074981 Q8SQS0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g17190
GO:0005634 nucleus C
IDA
SpoSPBC36.06c
SPAC6F12.13c
GO:0005737 cytoplasm C
IDA
SceS000003703
GO:0005783 endoplasmic reticulum C
IDA
SceS000003703
GO:0005829 cytosol C
IDA
SpoSPBC36.06c
SPAC6F12.13c
GO:0004161 dimethylallyltranstransferase activity F
IDA
SceS000003703
IGI
AthAt4g17190
At5g47770
SpoSPAC6F12.13c
NAS
DmeFBgn0025373
GO:0004337 geranyltranstransferase activity F
IDA
SceS000003703
IGI
AthAt4g17190
At5g47770
ISS
DmeFBgn0025373
SpoSPAC6F12.13c
NAS
DmeFBgn0025373
GO:0004660 protein farnesyltransferase activity F
IMP
SpoSPAC6F12.13c
SPBC36.06c
GO:0005515 protein binding F
IPI
SpoSPBC36.06c
SPAC6F12.13c
GO:0002119 nematode larval development P
IMP
CelWBGene00011058
GO:0006066 alcohol metabolic process P
RCA
SceS000003703
GO:0006696 ergosterol biosynthetic process P
IGI
SpoSPAC6F12.13c
ISS
SpoSPBC36.06c
TAS
SceS000003703
GO:0008299 isoprenoid biosynthetic process P
IDA
SceS000003703
ISS
SpoSPAC6F12.13c
GO:0008354 germ cell migration P
IMP
DmeFBgn0025373
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011058
GO:0018342 protein prenylation P
IC
SpoSPAC6F12.13c
IMP
SpoSPBC36.06c
GO:0030437 ascospore formation P
IMP
SpoSPBC36.06c
GO:0040007 growth P
IMP
CelWBGene00011058
GO:0045337 farnesyl diphosphate biosynthetic
process		 P
IC
DmeFBgn0025373
IDA
SceS000003703
IGI
AthAt4g17190
SpoSPAC6F12.13c
ISS
AthAt4g17190
At5g47770
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC6F12.13c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1519

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) FDPS GI:209571582
Pan troglodytes (Ptr) FDPS GI:114560083
Canis familiaris (Cfa) FDPS GI:73961593
Mus musculus (Mmu) Fdps
(MGI:104888)		 GI:19882207 Q3TMB3
Rattus norvegicus (Rno) Fdps
(RGD:68953)		 GI:13929206
Gallus gallus (Gga) FDPS GI:118108024
Drosophila melanogaster (Dme) Fpps
(FBgn0025373)		 GI:17137582
Anopheles gambiae (Aga) AgaP_AGAP007104 GI:158286274
Schizosaccharomyces pombe (Spo) SPAC6F12.13c GI:19114211 O14230
Saccharomyces cerevisiae (Sce) ERG20
(S000003703)		 GI:6322294 P08524
Kluyveromyces lactis (Kla) FPPS_KLULA GI:50302727
Eremothecium gossypii (Ego) AGOS_AEL122W GI:45190485
Magnaporthe grisea (Mgr) MGG_08649 GI:39948036
Neurospora crassa (Ncr) NCU01175.1 GI:32412376
Arabidopsis thaliana (Ath) FPS1 GI:15238801
Arabidopsis thaliana (Ath) FPS2 GI:15236002
Oryza sativa (Osa) Os05g0543400 GI:115465209
Oryza sativa (Osa) Os01g0703400 GI:115439441
Plasmodium falciparum (Pfa) PF11_0295 GI:124804318


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthFPS2
PfaPF11_0295
GO:0005625 soluble fraction C
ISO
MmuMGI:104888
GO:0005634 nucleus C
IDA
SpoSPAC6F12.13c
GO:0005737 cytoplasm C
IDA
SceS000003703
GO:0005739 mitochondrion C
IDA
MmuMGI:104888
GO:0005759 mitochondrial matrix C
ISO
MmuMGI:104888
GO:0005777 peroxisome C
ISO
MmuMGI:104888
GO:0005783 endoplasmic reticulum C
IDA
SceS000003703
GO:0005829 cytosol C
IDA
SpoSPAC6F12.13c
GO:0004161 dimethylallyltranstransferase activity F
IDA
SceS000003703
IGI
AthFPS2
FPS1
SpoSPAC6F12.13c
NAS
DmeFBgn0025373
GO:0004311 farnesyltranstransferase activity F
ISO
MmuMGI:104888
GO:0004337 geranyltranstransferase activity F
IDA
SceS000003703
IGI
AthFPS2
FPS1
ISO
MmuMGI:104888
ISS
DmeFBgn0025373
PfaPF11_0295
SpoSPAC6F12.13c
NAS
DmeFBgn0025373
GO:0004660 protein farnesyltransferase activity F
IMP
SpoSPAC6F12.13c
GO:0005515 protein binding F
IPI
SpoSPAC6F12.13c
GO:0006066 alcohol metabolic process P
RCA
SceS000003703
GO:0006696 ergosterol biosynthetic process P
IGI
SpoSPAC6F12.13c
TAS
SceS000003703
GO:0008299 isoprenoid biosynthetic process P
IDA
SceS000003703
ISO
MmuMGI:104888
ISS
SpoSPAC6F12.13c
GO:0008354 germ cell migration P
IMP
DmeFBgn0025373
GO:0018342 protein prenylation P
IC
SpoSPAC6F12.13c
GO:0045337 farnesyl diphosphate biosynthetic
process		 P
IC
DmeFBgn0025373
IDA
SceS000003703
IGI
AthFPS2
SpoSPAC6F12.13c
ISO
MmuMGI:104888
ISS
AthFPS2
FPS1
GO:0045542 positive regulation of cholesterol biosynthetic
process		 P
ISO
MmuMGI:104888
GO:0061051 positive regulation of cell growth involved in
cardiac muscle cell development		 P
ISO
MmuMGI:104888
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC6F12.13c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1294

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga2557 ENSANGP00000011119
Ashbya gossypii (Ago) ago2384 AEL122W
Arabidopsis thaliana (Ath) ath19576 At4g17190.1
Arabidopsis thaliana (Ath) ath19577 At4g17190.2
Arabidopsis thaliana (Ath) ath26664 At5g47770.1
Caenorhabditis elegans (Cel) cel13432 R06C1.2
(CE23901;
WBGene00011058)
Candida glabrata (Cgl) cgl4091 CAGL0L00319g
Cryptococcus neoformans (Cne) cne3243 167.m03590
Dictyostelium discoideum (Ddi) ddi396 DDB0190001
Dictyostelium discoideum (Ddi) ddi5894 DDB0206219
Dictyostelium discoideum (Ddi) ddi12375 DDB0215017
Debaryomyces hansenii (Dha) dha4789 DEHA0F09163g
Drosophila melanogaster (Dme) dme4471 CG12389-PA
(FBgn0025373)
Danio rerio (Dre) dre24889 ENSDARP00000040236
Danio rerio (Dre) dre6948 ENSDARP00000044295
Encephalitozoon cuniculi (Ecu) ecu1069 19074981
Takifugu rubripes (Fru) fru31342 SINFRUP00000131502
Gallus gallus (Gga) gga23869 ENSGALP00000023539
Homo sapiens (Hsa) hsa2214 ENSP00000292252
Homo sapiens (Hsa) hsa2213 ENSP00000349078
(FDPS)		 P14324
Kluyveromyces lactis (Kla) kla297 KLLA0A06732g
Mus musculus (Mmu) mmu31242 ENSMUSP00000080531
(MGI:104888)		 Q920E5
Neurospora crassa (Ncr) ncr1138 NCU01175.2
Oryza sativa (Osa) osa10670 2782.m00125
Oryza sativa (Osa) osa15418 2991.m00148
Oryza sativa (Osa) osa14186 3005.m00049
Oryza sativa (Osa) osa34898 4761.m00151
Oryza sativa (Osa) osa45217 5383.m00122
Plasmodium falciparum (Pfa) pfa746 PF11_0295
Rattus norvegicus (Rno) rno16403 ENSRNOP00000027659
Rattus norvegicus (Rno) rno23685 ENSRNOP00000048400
Saccharomyces cerevisiae (Sce) sce3432 YJL167W
(S000003703)
Schizosaccharomyces pombe (Spo) spo4682 SPAC6F12.13c O14230
Yarrowia lipolytica (Yli) yli4103 YALI0E05753g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g17190
PfaPF11_0295
GO:0005625 soluble fraction C
ISO
MmuMGI:104888
GO:0005634 nucleus C
IDA
SpoSPAC6F12.13c
GO:0005737 cytoplasm C
IDA
SceS000003703
GO:0005739 mitochondrion C
IDA
MmuMGI:104888
GO:0005759 mitochondrial matrix C
ISO
MmuMGI:104888
GO:0005777 peroxisome C
ISO
MmuMGI:104888
GO:0005783 endoplasmic reticulum C
IDA
SceS000003703
GO:0005829 cytosol C
IDA
SpoSPAC6F12.13c
GO:0004161 dimethylallyltranstransferase activity F
IDA
SceS000003703
IGI
AthAt4g17190
At5g47770
SpoSPAC6F12.13c
NAS
DmeFBgn0025373
GO:0004311 farnesyltranstransferase activity F
ISO
MmuMGI:104888
GO:0004337 geranyltranstransferase activity F
IDA
SceS000003703
IGI
AthAt4g17190
At5g47770
ISO
MmuMGI:104888
ISS
DmeFBgn0025373
PfaPF11_0295
SpoSPAC6F12.13c
NAS
DmeFBgn0025373
GO:0004660 protein farnesyltransferase activity F
IMP
SpoSPAC6F12.13c
GO:0005515 protein binding F
IPI
SpoSPAC6F12.13c
GO:0002119 nematode larval development P
IMP
CelWBGene00011058
GO:0006066 alcohol metabolic process P
RCA
SceS000003703
GO:0006696 ergosterol biosynthetic process P
IGI
SpoSPAC6F12.13c
TAS
SceS000003703
GO:0008299 isoprenoid biosynthetic process P
IDA
SceS000003703
ISO
MmuMGI:104888
ISS
SpoSPAC6F12.13c
GO:0008354 germ cell migration P
IMP
DmeFBgn0025373
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011058
GO:0018342 protein prenylation P
IC
SpoSPAC6F12.13c
GO:0040007 growth P
IMP
CelWBGene00011058
GO:0045337 farnesyl diphosphate biosynthetic
process		 P
IC
DmeFBgn0025373
IDA
SceS000003703
IGI
AthAt4g17190
SpoSPAC6F12.13c
ISO
MmuMGI:104888
ISS
AthAt4g17190
At5g47770
GO:0045542 positive regulation of cholesterol biosynthetic
process		 P
ISO
MmuMGI:104888
GO:0061051 positive regulation of cell growth involved in
cardiac muscle cell development		 P
ISO
MmuMGI:104888
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC6F12.13c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC36.06c
(O59703)		 YJL167W
(S000003703)
SPAC6F12.13c
(O14230)		 YJL167W
(S000003703)