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Search term: YJL180C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ATP12
SGD link S000003716
Alternative ID YJL180C
Description Conserved protein required for assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase; mutation of human ATP12 reduces active ATP synthase levels and is associated with the disorder ATPAF2 deficiency
Synonyms YJL180C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3015 ACDHYP-

KOGs classification KOGs description
METABOLISM F1-ATP synthase assembly protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g40660 GI:15237466
Caenorhabditis elegans (Cel) CE23335 GI:17544454
Drosophila melanogaster (Dme) 7298774 GI:7298774 Q9VID7
Homo sapiens (Hsa) Hs17459138 GI:17459138
Homo sapiens (Hsa) Hs21735485
(ATPAF2)		 GI:21735485 Q8N5M1
Saccharomyces cerevisiae (Sce) YJL180c
(S000003716)		 GI:6322281 P22135
Schizosaccharomyces pombe (Spo) SPAC9.12c GI:19114267 Q9UT16


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g40660
GO:0005739 mitochondrion C
IDA
SceS000003716
SpoSPAC9.12c
GO:0005759 mitochondrial matrix C
ISS
SpoSPAC9.12c
GO:0016607 nuclear speck C
IDA
HsaATPAF2
GO:0005515 protein binding F
IPI
HsaATPAF2
GO:0019904 protein domain specific binding F
IPI
SceS000003716
GO:0051082 unfolded protein binding F
ISS
SpoSPAC9.12c
GO:0033615 mitochondrial proton-transporting ATP synthase
complex assembly		 P
IMP
SceS000003716
IPI
SceS000003716
ISS
SpoSPAC9.12c
GO:0043461 proton-transporting ATP synthase complex
assembly		 P
NAS
HsaATPAF2

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
34602

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ATPAF2 GI:21735485 Q8N5M1
Pan troglodytes (Ptr) ATPAF2 GI:114668880
Canis familiaris (Cfa) ATPAF2 GI:57086735
Mus musculus (Mmu) Atpaf2
(MGI:2180561)		 GI:21703852 Q91YY4
Rattus norvegicus (Rno) Atpaf2 GI:62656170
Gallus gallus (Gga) ATPAF2 GI:50755603
Drosophila melanogaster (Dme) l(2)k14505
(FBgn0021856)		 GI:24585626
Anopheles gambiae (Aga) AgaP_AGAP008876 GI:158299506
Caenorhabditis elegans (Cel) Y116A8C.27
(CE37421;
WBGene00013804)		 GI:71995783
Schizosaccharomyces pombe (Spo) atp12
(SPAC9.12c)		 GI:19114267 Q9UT16
Saccharomyces cerevisiae (Sce) ATP12
(S000003716)		 GI:6322281 P22135
Kluyveromyces lactis (Kla) KLLA0A06259g GI:50302687
Eremothecium gossypii (Ego) AGOS_AEL140C GI:45190467
Magnaporthe grisea (Mgr) MGG_02782 GI:39970631
Neurospora crassa (Ncr) NCU00676.1 GI:32408751
Arabidopsis thaliana (Ath) AT5G40660 GI:15237466
Oryza sativa (Osa) Os07g0644000 GI:115473693


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g40660
MmuMGI:2180561
GO:0005739 mitochondrion C
IDA
MmuMGI:2180561
SceS000003716
SpoSPAC9.12c
GO:0005759 mitochondrial matrix C
ISS
SpoSPAC9.12c
GO:0016607 nuclear speck C
IDA
HsaATPAF2
GO:0003674 molecular_function F
ND
MmuMGI:2180561
GO:0005515 protein binding F
IPI
HsaATPAF2
GO:0019904 protein domain specific binding F
IPI
SceS000003716
GO:0051082 unfolded protein binding F
ISS
SpoSPAC9.12c
GO:0008150 biological_process P
ND
MmuMGI:2180561
GO:0033615 mitochondrial proton-transporting ATP synthase
complex assembly		 P
IMP
SceS000003716
IPI
SceS000003716
ISS
SpoSPAC9.12c
GO:0043461 proton-transporting ATP synthase complex
assembly		 P
NAS
HsaATPAF2

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3851

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga10936 ENSANGP00000013879
Ashbya gossypii (Ago) ago2366 AEL140C
Arabidopsis thaliana (Ath) ath25842 At5g40660.1
Caenorhabditis elegans (Cel) cel17731 Y116A8C.27
(CE37421;
WBGene00013804)
Candida glabrata (Cgl) cgl1949 CAGL0G07513g
Cryptococcus neoformans (Cne) cne5421 179.m00274
Dictyostelium discoideum (Ddi) ddi11205 DDB0184519
Debaryomyces hansenii (Dha) dha1538 DEHA0C02398g
Drosophila melanogaster (Dme) dme3247 CG8674-PA
(FBgn0021856)
Danio rerio (Dre) dre3359 ENSDARP00000025670
Takifugu rubripes (Fru) fru7740 SINFRUP00000141758
Gallus gallus (Gga) gga6497 ENSGALP00000007866
(ATPAF2)
Homo sapiens (Hsa) hsa13173 ENSP00000304017
Kluyveromyces lactis (Kla) kla276 KLLA0A06259g
Mus musculus (Mmu) mmu3829 ENSMUSP00000047801
(MGI:2180561)		 Q91YY4
Neurospora crassa (Ncr) ncr656 NCU00676.2
Oryza sativa (Osa) osa56652 6197.m00155
Rattus norvegicus (Rno) rno5174 ENSRNOP00000004948
(RGD:1305161)
Saccharomyces cerevisiae (Sce) sce3445 YJL180C
(S000003716)
Schizosaccharomyces pombe (Spo) spo2524 SPAC9.12c Q9UT16
Yarrowia lipolytica (Yli) yli2494 YALI0C19448g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g40660
MmuMGI:2180561
GO:0005739 mitochondrion C
IDA
MmuMGI:2180561
SceS000003716
SpoSPAC9.12c
GO:0005759 mitochondrial matrix C
ISS
SpoSPAC9.12c
GO:0003674 molecular_function F
ND
MmuMGI:2180561
GO:0019904 protein domain specific binding F
IPI
SceS000003716
GO:0051082 unfolded protein binding F
ISS
SpoSPAC9.12c
GO:0008150 biological_process P
ND
MmuMGI:2180561
GO:0033615 mitochondrial proton-transporting ATP synthase
complex assembly		 P
IMP
SceS000003716
IPI
SceS000003716
ISS
SpoSPAC9.12c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC9.12c
(Q9UT16)		 YJL180C
(S000003716)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000003716
SpoSPAC9.12c
GO:0005759 mitochondrial matrix C
ISS
SpoSPAC9.12c
GO:0019904 protein domain specific binding F
IPI
SceS000003716
GO:0051082 unfolded protein binding F
ISS
SpoSPAC9.12c
GO:0033615 mitochondrial proton-transporting ATP synthase
complex assembly		 P
IMP
SceS000003716
IPI
SceS000003716
ISS
SpoSPAC9.12c

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