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Search term: YJL194W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CDC6
SGD link S000003730
Alternative ID YJL194W
Description Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p
Synonyms YJL194W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2227 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGCELLULAR PROCESSES AND SIGNALING Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g07270 GI:15222350
Arabidopsis thaliana (Ath) At2g29680 GI:15227603
Caenorhabditis elegans (Cel) CE08688
(WBGene00000382)		 GI:17506005 P91155
Drosophila melanogaster (Dme) 7295060 GI:7295060
Homo sapiens (Hsa) Hs4502703
(CDC6)		 GI:4502703 Q99741
Saccharomyces cerevisiae (Sce) YJL194w
(S000003730)		 GI:6322266 P09119
Schizosaccharomyces pombe (Spo) SPBC14C8.07c GI:19112702 P41411
Encephalitozoon cuniculi (Ecu) ECU09g0220 GI:19173142


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
CelWBGene00000382
GO:0005634 nucleus C
IDA
CelWBGene00000382
GO:0005654 nucleoplasm C
EXP
HsaCDC6
GO:0005656 pre-replicative complex C
IDA
SceS000003730
ISS
SpoSPBC14C8.07c
GO:0005730 nucleolus C
IDA
CelWBGene00000382
GO:0005737 cytoplasm C
IDA
CelWBGene00000382
GO:0005829 cytosol C
EXP
HsaCDC6
GO:0031261 DNA replication preinitiation complex C
IDA
SceS000003730
GO:0043596 nuclear replication fork C
IC
SpoSPBC14C8.07c
GO:0003682 chromatin binding F
IDA
SceS000003730
IMP
SceS000003730
GO:0003688 DNA replication origin binding F
IDA
SceS000003730
GO:0003689 DNA clamp loader activity F
ISS
SpoSPBC14C8.07c
GO:0003924 GTPase activity F
IDA
SceS000003730
GO:0005515 protein binding F
IPI
HsaCDC6
SceS000003730
GO:0005524 ATP binding F
IDA
SceS000003730
IMP
SceS000003730
ISS
SpoSPBC14C8.07c
GO:0005525 GTP binding F
IDA
SceS000003730
GO:0016887 ATPase activity F
IDA
SceS000003730
GO:0000003 reproduction P
IMP
CelWBGene00000382
GO:0000076 DNA replication checkpoint P
IMP
SpoSPBC14C8.07c
TAS
HsaCDC6
GO:0000079 regulation of cyclin-dependent protein kinase
activity		 P
TAS
HsaCDC6
GO:0000082 G1/S transition of mitotic cell
cycle		 P
IMP
SceS000003730
GO:0000087 M phase of mitotic cell cycle P
NAS
SpoSPBC14C8.07c
GO:0002119 nematode larval development P
IMP
CelWBGene00000382
GO:0006200 ATP catabolic process P
ISS
SpoSPBC14C8.07c
GO:0006260 DNA replication P
EXP
HsaCDC6
ISS
AthAt2g29680
At1g07270
GO:0006267 pre-replicative complex assembly P
IDA
SceS000003730
IMP
SceS000003730
ISS
SpoSPBC14C8.07c
GO:0006270 DNA-dependent DNA replication initiation P
IMP
SpoSPBC14C8.07c
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000382
GO:0007089 traversing start control point of mitotic cell
cycle		 P
TAS
HsaCDC6
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC14C8.07c
GO:0008156 negative regulation of DNA replication P
TAS
HsaCDC6
GO:0008285 negative regulation of cell proliferation P
TAS
HsaCDC6
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000382
GO:0030174 regulation of DNA-dependent DNA replication
initiation		 P
IMP
SceS000003730
GO:0031938 regulation of chromatin silencing at
telomere		 P
IMP
SceS000003730
GO:0040007 growth P
IMP
CelWBGene00000382
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00000382
GO:0051726 regulation of cell cycle P
ISS
AthAt1g07270
At2g29680
RCA
SceS000003730

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68763

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) CDC6
(S000003730)		 GI:6322266 P09119
Kluyveromyces lactis (Kla) KLLA0C03586g GI:50304801
Eremothecium gossypii (Ego) AGOS_AFR621C GI:45199139


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005656 pre-replicative complex C
IDA
SceS000003730
GO:0031261 DNA replication preinitiation complex C
IDA
SceS000003730
GO:0003682 chromatin binding F
IDA
SceS000003730
IMP
SceS000003730
GO:0003688 DNA replication origin binding F
IDA
SceS000003730
GO:0003924 GTPase activity F
IDA
SceS000003730
GO:0005515 protein binding F
IPI
SceS000003730
GO:0005524 ATP binding F
IDA
SceS000003730
IMP
SceS000003730
GO:0005525 GTP binding F
IDA
SceS000003730
GO:0016887 ATPase activity F
IDA
SceS000003730
GO:0000082 G1/S transition of mitotic cell
cycle		 P
IMP
SceS000003730
GO:0006267 pre-replicative complex assembly P
IDA
SceS000003730
IMP
SceS000003730
GO:0030174 regulation of DNA-dependent DNA replication
initiation		 P
IMP
SceS000003730
GO:0031938 regulation of chromatin silencing at
telomere		 P
IMP
SceS000003730
GO:0051726 regulation of cell cycle P
RCA
SceS000003730

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2922

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga565 ENSANGP00000015641
Ashbya gossypii (Ago) ago3813 AFR621C
Arabidopsis thaliana (Ath) ath703 At1g07270.1
Arabidopsis thaliana (Ath) ath9941 At2g29680.1
Arabidopsis thaliana (Ath) ath9942 At2g29680.2
Caenorhabditis elegans (Cel) cel3921 C43E11.10
(CE08688;
WBGene00000382)
Candida glabrata (Cgl) cgl3545 CAGL0K00605g
Dictyostelium discoideum (Ddi) ddi3995 DDB0203551
Debaryomyces hansenii (Dha) dha6177 DEHA0G10780g
Drosophila melanogaster (Dme) dme8614 CG5971-PA
(FBgn0035918)
Danio rerio (Dre) dre26142 ENSDARP00000008736
(LOC402825)		 Q7SZP5
Takifugu rubripes (Fru) fru25843 SINFRUP00000159520
Homo sapiens (Hsa) hsa13608 ENSP00000209728
(CDC6)		 Q99741
Kluyveromyces lactis (Kla) kla1355 KLLA0C03586g
Mus musculus (Mmu) mmu4742 ENSMUSP00000050339
Neurospora crassa (Ncr) ncr2688 NCU02776.2
Oryza sativa (Osa) osa46872 5539.m00093
Oryza sativa (Osa) osa46920 5539.m00129
Oryza sativa (Osa) osa46923 5539.m00130
Oryza sativa (Osa) osa46925 5539.m00131
Rattus norvegicus (Rno) rno6049 ENSRNOP00000032177
(RGD:1309157)
Saccharomyces cerevisiae (Sce) sce3459 YJL194W
(S000003730)
Schizosaccharomyces pombe (Spo) spo3885 SPBC14C8.07c P41411
Yarrowia lipolytica (Yli) yli1750 YALI0C00671g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
CelWBGene00000382
GO:0005634 nucleus C
IDA
CelWBGene00000382
DmeFBgn0035918
GO:0005656 pre-replicative complex C
IDA
SceS000003730
ISS
DmeFBgn0035918
SpoSPBC14C8.07c
GO:0005730 nucleolus C
IDA
CelWBGene00000382
GO:0005737 cytoplasm C
IDA
CelWBGene00000382
GO:0031261 DNA replication preinitiation complex C
IDA
SceS000003730
GO:0043596 nuclear replication fork C
IC
SpoSPBC14C8.07c
GO:0003682 chromatin binding F
IDA
SceS000003730
IMP
SceS000003730
GO:0003688 DNA replication origin binding F