Bahler Lab

Search term: YJR048W

Gene summary:

Species Saccharomyces cerevisiae (Sce)

Primary name CYC1

SGD link S000003809

Alternative ID YJR048W

Description Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration

Synonyms YJR048W

Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)

KOG3453 ACDHYP-

KOGs classification KOGs description

METABOLISM Cytochrome c

GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations

GO:0000159 protein phosphatase type 2A complex C
TAS
Hsa CYCS

GO:0005575 cellular_component C
ND
Ath At4g10040

GO:0005634 nucleus C
IDA
Hsa CYCS
Spo SPCC191.07

GO:0005739 mitochondrion C
IDA
Ath At1g22840
Dme FBgn0000409
Sce S000000765
S000003809

GO:0005743 mitochondrial inner membrane C
ISS
Dme FBgn0000409

GO:0005746 mitochondrial respiratory chain C
ISS
Spo SPCC191.07

GO:0005758 mitochondrial intermembrane space C
IDA
Sce S000000765
S000003809
TAS
Hsa CYCS

GO:0005759 mitochondrial matrix C
ISS
Dme FBgn0000409

GO:0005829 cytosol C
EXP
Hsa CYCS
IDA
Spo SPCC191.07
IMP
Hsa CYCS

GO:0005886 plasma membrane C
IDA
Ath At1g22840

GO:0004722 protein serine/threonine phosphatase
activity F
TAS
Hsa CYCS

GO:0005507 copper ion binding F
IDA
Ath At4g10040
At1g22840

GO:0005515 protein binding F
IPI
Hsa CYCS

GO:0009055 electron carrier activity F
IDA
Dme FBgn0000409
Sce S000000765
S000003809
ISS
Ath At4g10040
At1g22840
Dme FBgn0000409

GO:0020037 heme binding F
TAS
Hsa CYCS

GO:0045155 electron transporter, transferring electrons from
CoQH2-cytochrome c reductase complex and
cytochrome c oxidase complex activity F
IDA
Hsa CYCS
ISS
Dme FBgn0000409
Spo SPCC191.07

GO:0002119 nematode larval development P
IMP
Cel WBGene00017121

GO:0006119 oxidative phosphorylation P
ISS
Dme FBgn0000409

GO:0006122 mitochondrial electron transport, ubiquinol to
cytochrome c P
IDA
Sce S000000765
S000003809
ISS
Spo SPCC191.07

GO:0006123 mitochondrial electron transport, cytochrome c to
oxygen P
IDA
Sce S000000765
S000003809
ISS
Spo SPCC191.07

GO:0006309 DNA fragmentation involved in apoptotic nuclear
change P
IMP
Hsa CYCS

GO:0006915 apoptosis P
IDA
Hsa CYCS

GO:0008283 cell proliferation P
TAS
Ath At1g22840

GO:0008340 determination of adult lifespan P
IMP
Cel WBGene00017121

GO:0008635 activation of caspase activity by cytochrome
c P
TAS
Hsa CYCS

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00017121
WBGene00013854

GO:0040007 growth P
IMP
Cel WBGene00017121

GO:0040010 positive regulation of growth rate P
IMP
Cel WBGene00013854
WBGene00017121

GO:0040018 positive regulation of multicellular organism
growth P
IMP
Cel WBGene00013854

GO:0045333 cellular respiration P
TAS
Hsa CYCS

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern

68675

Species Gene ID NCBI link UniProt link

Pan troglodytes (Ptr) LOC742456 GI:114691183

Mus musculus (Mmu) Cycs
(MGI:88578) GI:6681095 P62897

Mus musculus (Mmu) Gm10053 GI:149270454

Rattus norvegicus (Rno) LOC690675 GI:109488076

Gallus gallus (Gga) CYCS GI:118085869

Drosophila melanogaster (Dme) Cyt-c-p
(FBgn0000409) GI:17137228

Anopheles gambiae (Aga) AgaP_AGAP009537 GI:31202411

Caenorhabditis elegans (Cel) cyc-2.2
(CE06565;
WBGene00013854) GI:17566554 Q23240

Caenorhabditis elegans (Cel) cyc-2.1
(CE16968;
WBGene00017121) GI:17539604 P19974

Saccharomyces cerevisiae (Sce) CYC1
(S000003809) GI:6322508 P00044

Plasmodium falciparum (Pfa) PF14_0038 GI:124808051

GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005625 soluble fraction C
IDA
Mmu MGI:88578
ISO
Mmu MGI:88578

GO:0005739 mitochondrion C
IDA
Dme FBgn0000409
Mmu MGI:88578
Sce S000003809
ISO
Mmu MGI:88578

GO:0005743 mitochondrial inner membrane C
ISS
Dme FBgn0000409

GO:0005746 mitochondrial respiratory chain C
ISS
Pfa PF14_0038

GO:0005758 mitochondrial intermembrane space C
IDA
Sce S000003809

GO:0005759 mitochondrial matrix C
ISS
Dme FBgn0000409

GO:0005829 cytosol C
IDA
Mmu MGI:88578
ISO
Mmu MGI:88578

GO:0009055 electron carrier activity F
IDA
Dme FBgn0000409
Sce S000003809
ISO
Mmu MGI:88578
ISS
Dme FBgn0000409

GO:0020037 heme binding F
IDA
Mmu MGI:88578

GO:0045155 electron transporter, transferring electrons from
CoQH2-cytochrome c reductase complex and
cytochrome c oxidase complex activity F
ISS
Dme FBgn0000409

GO:0002119 nematode larval development P
IMP
Cel WBGene00017121

GO:0006119 oxidative phosphorylation P
ISS
Dme FBgn0000409

GO:0006122 mitochondrial electron transport, ubiquinol to
cytochrome c P
IDA
Sce S000003809

GO:0006123 mitochondrial electron transport, cytochrome c to
oxygen P
IDA
Sce S000003809
ISO
Mmu MGI:88578

GO:0006915 apoptosis P
IDA
Mmu MGI:88578
ISO
Mmu MGI:88578

GO:0006979 response to oxidative stress P
ISO
Mmu MGI:88578

GO:0008340 determination of adult lifespan P
IMP
Cel WBGene00017121

GO:0008635 activation of caspase activity by cytochrome
c P
IMP
Mmu MGI:88578

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00017121
WBGene00013854

GO:0040007 growth P
IMP
Cel WBGene00017121

GO:0040010 positive regulation of growth rate P
IMP
Cel WBGene00013854
WBGene00017121

GO:0040018 positive regulation of multicellular organism
growth P
IMP
Cel WBGene00013854

GO:0042743 hydrogen peroxide metabolic process P
IDA
Mmu MGI:88578

GO:0043065 positive regulation of apoptosis P
IDA
Mmu MGI:88578

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern

OG1_960

Species OrthoMCL
sequence Model organism
protein page UniProt link

Anopheles gambiae (Aga) aga11692 ENSANGP00000020091

Ashbya gossypii (Ago) ago3552 AFR360W

Arabidopsis thaliana (Ath) ath2451 At1g22840.1

Arabidopsis thaliana (Ath) ath18733 At4g10040.1

Caenorhabditis elegans (Cel) cel5297 E04A4.7
(CE16968;
WBGene00017121)

Caenorhabditis elegans (Cel) cel21137 ZC116.2
(CE06565;
WBGene00013854)

Candida glabrata (Cgl) cgl2587 CAGL0I01408g

Cryptococcus neoformans (Cne) cne2401 181.m08438

Dictyostelium discoideum (Ddi) ddi11695 DDB0216257

Debaryomyces hansenii (Dha) dha2039 DEHA0C13805g

Drosophila melanogaster (Dme) dme2657 CG13263-PA
(FBgn0000408)

Drosophila melanogaster (Dme) dme2658 CG17903-PA
(FBgn0000409)

Danio rerio (Dre) dre29356 ENSDARP00000034555
(zgc:86706) Q6IQM2

Takifugu rubripes (Fru) fru11199 SINFRUP00000131815

Takifugu rubripes (Fru) fru5702 SINFRUP00000136952

Takifugu rubripes (Fru) fru22191 SINFRUP00000159057

Gallus gallus (Gga) gga9867 ENSGALP00000017934
(CYCS) P67881

Homo sapiens (Hsa) hsa28344 ENSP00000307786
(CYCS) P99999

Homo sapiens (Hsa) hsa30158 ENSP00000332279

Homo sapiens (Hsa) hsa1970 ENSP00000354740

Kluyveromyces lactis (Kla) kla4840 KLLA0F16929g

Kluyveromyces lactis (Kla) kla4841 KLLA0F16940g

Mus musculus (Mmu) mmu14816 ENSMUSP00000028430
(MGI:88579) P00015

Mus musculus (Mmu) mmu13533 ENSMUSP00000072829
(MGI:88578) P62897

Mus musculus (Mmu) mmu21855 ENSMUSP00000076944
(MGI:88578) P62897

Neurospora crassa (Ncr) ncr1760 NCU01808.2

Oryza sativa (Osa) osa38045 5033.m00143

Oryza sativa (Osa) osa61915 6490.m00185

Plasmodium falciparum (Pfa) pfa1258 PF14_0038

Rattus norvegicus (Rno) rno18830 ENSRNOP00000008371
(RGD:2452) P10715

Rattus norvegicus (Rno) rno21255 ENSRNOP00000014058
(RGD:2451) P62898

Rattus norvegicus (Rno) rno14312 ENSRNOP00000041521
(RGD:2451) P62898

Rattus norvegicus (Rno) rno4921 ENSRNOP00000047596
(GI:690675)

Saccharomyces cerevisiae (Sce) sce1665 YEL039C
(S000000765)

Saccharomyces cerevisiae (Sce) sce3543 YJR048W
(S000003809)

Schizosaccharomyces pombe (Spo) spo2613 SPCC191.07 P00046

Yarrowia lipolytica (Yli) yli3096 YALI0D09273g

GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005575 cellular_component C
ND
Ath At4g10040

GO:0005625 soluble fraction C
IDA
Mmu MGI:88578
ISO
Mmu MGI:88578

GO:0005634 nucleus C
IDA
Spo SPCC191.07

GO:0005739 mitochondrion C
IDA
Ath At1g22840
Dme FBgn0000409
Mmu MGI:88578
MGI:88579
Sce S000000765
S000003809
ISO
Mmu MGI:88578

GO:0005743 mitochondrial inner membrane C
ISS
Dme FBgn0000409

GO:0005746 mitochondrial respiratory chain C
ISS
Pfa PF14_0038
Spo SPCC191.07

GO:0005758 mitochondrial intermembrane space C
IDA
Sce S000000765
S000003809

GO:0005759 mitochondrial matrix C
ISS
Dme FBgn0000409

GO:0005829 cytosol C
IDA
Mmu MGI:88578
Spo SPCC191.07
ISO
Mmu MGI:88578

GO:0005886 plasma membrane C
IDA
Ath At1g22840

GO:0005507 copper ion binding F
IDA
Ath At4g10040
At1g22840

GO:0009055 electron carrier activity F
IDA
Dme FBgn0000409
Sce S000000765
S000003809
ISO
Mmu MGI:88578
ISS
Ath At4g10040
At1g22840
Dme FBgn0000409

GO:0020037 heme binding F
IDA
Mmu MGI:88578
MGI:88579

GO:0045155 electron transporter, transferring electrons from
CoQH2-cytochrome c reductase complex and
cytochrome c oxidase complex activity F
ISS
Dme FBgn0000409
Spo SPCC191.07

GO:0002119 nematode larval development P
IMP
Cel WBGene00017121

GO:0006119 oxidative phosphorylation P
ISS
Dme FBgn0000409

GO:0006122 mitochondrial electron transport, ubiquinol to
cytochrome c P
IDA
Sce S000000765
S000003809
ISS
Spo SPCC191.07

GO:0006123 mitochondrial electron transport, cytochrome c to
oxygen P
IDA
Sce S000000765
S000003809
ISO
Mmu MGI:88578
ISS
Spo SPCC191.07

GO:0006915 apoptosis P
IDA
Mmu MGI:88578
MGI:88579
ISO
Mmu MGI:88578

GO:0006979 response to oxidative stress P
ISO
Mmu MGI:88578

GO:0008283 cell proliferation P
TAS
Ath At1g22840

GO:0008340 determination of adult lifespan P
IMP
Cel WBGene00017121

GO:0008635 activation of caspase activity by cytochrome
c P
IMP
Mmu MGI:88578

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00017121
WBGene00013854

GO:0040007 growth P
IMP
Cel WBGene00017121

GO:0040010 positive regulation of growth rate P
IMP
Cel WBGene00013854
WBGene00017121

GO:0040018 positive regulation of multicellular organism
growth P
IMP
Cel WBGene00013854

GO:0042743 hydrogen peroxide metabolic process P
IDA
Mmu MGI:88578
MGI:88579

GO:0043065 positive regulation of apoptosis P
IDA
Mmu MGI:88578

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Curated yeast ortholog results:

S. pombe
systematic ID S. cerevisiae
systematic ID

SPCC191.07
(P00046) YJR048W
(S000003809)

GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005634 nucleus C
IDA
Spo SPCC191.07

GO:0005739 mitochondrion C
IDA
Sce S000003809

GO:0005746 mitochondrial respiratory chain C
ISS
Spo SPCC191.07

GO:0005758 mitochondrial intermembrane space C
IDA
Sce S000003809

GO:0005829 cytosol C
IDA
Spo SPCC191.07

GO:0009055 electron carrier activity F
IDA
Sce S000003809

GO:0045155 electron transporter, transferring electrons from
CoQH2-cytochrome c reductase complex and
cytochrome c oxidase complex activity F
ISS
Spo SPCC191.07

GO:0006122 mitochondrial electron transport, ubiquinol to
cytochrome c P
IDA
Sce S000003809
ISS
Spo SPCC191.07

GO:0006123 mitochondrial electron transport, cytochrome c to
oxygen P
IDA
Sce S000003809
ISS
Spo SPCC191.07

Back to the top

YOGY Home

YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

s.khadayate@ucl.ac.uk

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG3453	ACDHYP-

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At1g22840	GI:15219956
Arabidopsis thaliana (Ath)	At4g10040	GI:15234910
Caenorhabditis elegans (Cel)	CE06565 (WBGene00013854)	GI:17566554	Q23240
Caenorhabditis elegans (Cel)	CE16968 (WBGene00017121)	GI:17539604	P19974
Drosophila melanogaster (Dme)	7298325	GI:17137204
Drosophila melanogaster (Dme)	7298326 (FBgn0000409)	GI:17137228
Homo sapiens (Hsa)	Hs11128019 (CYCS)	GI:11128019	Q6LER6
Homo sapiens (Hsa)	Hs17447859	GI:17447859
Homo sapiens (Hsa)	Hs17449154_1	GI:17449154
Homo sapiens (Hsa)	Hs17450041	GI:17450041
Homo sapiens (Hsa)	Hs17459654	GI:17459654
Homo sapiens (Hsa)	Hs17477127	GI:17477127
Homo sapiens (Hsa)	Hs17487860	GI:17487860
Homo sapiens (Hsa)	Hs18593198	GI:18593198
Homo sapiens (Hsa)	Hs20533109_2	GI:20533109
Homo sapiens (Hsa)	Hs20533316	GI:20533316
Homo sapiens (Hsa)	Hs20546100	GI:20546100
Homo sapiens (Hsa)	Hs20548491	GI:20548491
Homo sapiens (Hsa)	Hs20551195	GI:20551195
Homo sapiens (Hsa)	Hs22045558	GI:22045558
Homo sapiens (Hsa)	Hs22045958	GI:22045958
Homo sapiens (Hsa)	Hs22059355	GI:22059355
Homo sapiens (Hsa)	Hs22060072	GI:14782885
Homo sapiens (Hsa)	Hs22064236	GI:22064236
Saccharomyces cerevisiae (Sce)	YEL039c (S000000765)	GI:6320796	P00045
Saccharomyces cerevisiae (Sce)	YJR048w (S000003809)	GI:6322508	P00044
Schizosaccharomyces pombe (Spo)	SPCC191.07	GI:19075796	P00046

Species	Gene ID	NCBI link	UniProt link
Pan troglodytes (Ptr)	LOC742456	GI:114691183
Mus musculus (Mmu)	Cycs (MGI:88578)	GI:6681095	P62897
Mus musculus (Mmu)	Gm10053	GI:149270454
Rattus norvegicus (Rno)	LOC690675	GI:109488076
Gallus gallus (Gga)	CYCS	GI:118085869
Drosophila melanogaster (Dme)	Cyt-c-p (FBgn0000409)	GI:17137228
Anopheles gambiae (Aga)	AgaP_AGAP009537	GI:31202411
Caenorhabditis elegans (Cel)	cyc-2.2 (CE06565; WBGene00013854)	GI:17566554	Q23240
Caenorhabditis elegans (Cel)	cyc-2.1 (CE16968; WBGene00017121)	GI:17539604	P19974
Saccharomyces cerevisiae (Sce)	CYC1 (S000003809)	GI:6322508	P00044
Plasmodium falciparum (Pfa)	PF14_0038	GI:124808051

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Anopheles gambiae (Aga)	aga11692	ENSANGP00000020091
Ashbya gossypii (Ago)	ago3552	AFR360W
Arabidopsis thaliana (Ath)	ath2451	At1g22840.1
Arabidopsis thaliana (Ath)	ath18733	At4g10040.1
Caenorhabditis elegans (Cel)	cel5297	E04A4.7 (CE16968; WBGene00017121)
Caenorhabditis elegans (Cel)	cel21137	ZC116.2 (CE06565; WBGene00013854)
Candida glabrata (Cgl)	cgl2587	CAGL0I01408g
Cryptococcus neoformans (Cne)	cne2401	181.m08438
Dictyostelium discoideum (Ddi)	ddi11695	DDB0216257
Debaryomyces hansenii (Dha)	dha2039	DEHA0C13805g
Drosophila melanogaster (Dme)	dme2657	CG13263-PA (FBgn0000408)
Drosophila melanogaster (Dme)	dme2658	CG17903-PA (FBgn0000409)
Danio rerio (Dre)	dre29356	ENSDARP00000034555 (zgc:86706)	Q6IQM2
Takifugu rubripes (Fru)	fru11199	SINFRUP00000131815
Takifugu rubripes (Fru)	fru5702	SINFRUP00000136952
Takifugu rubripes (Fru)	fru22191	SINFRUP00000159057
Gallus gallus (Gga)	gga9867	ENSGALP00000017934 (CYCS)	P67881
Homo sapiens (Hsa)	hsa28344	ENSP00000307786 (CYCS)	P99999
Homo sapiens (Hsa)	hsa30158	ENSP00000332279
Homo sapiens (Hsa)	hsa1970	ENSP00000354740
Kluyveromyces lactis (Kla)	kla4840	KLLA0F16929g
Kluyveromyces lactis (Kla)	kla4841	KLLA0F16940g
Mus musculus (Mmu)	mmu14816	ENSMUSP00000028430 (MGI:88579)	P00015
Mus musculus (Mmu)	mmu13533	ENSMUSP00000072829 (MGI:88578)	P62897
Mus musculus (Mmu)	mmu21855	ENSMUSP00000076944 (MGI:88578)	P62897
Neurospora crassa (Ncr)	ncr1760	NCU01808.2
Oryza sativa (Osa)	osa38045	5033.m00143
Oryza sativa (Osa)	osa61915	6490.m00185
Plasmodium falciparum (Pfa)	pfa1258	PF14_0038
Rattus norvegicus (Rno)	rno18830	ENSRNOP00000008371 (RGD:2452)	P10715
Rattus norvegicus (Rno)	rno21255	ENSRNOP00000014058 (RGD:2451)	P62898
Rattus norvegicus (Rno)	rno14312	ENSRNOP00000041521 (RGD:2451)	P62898
Rattus norvegicus (Rno)	rno4921	ENSRNOP00000047596 (GI:690675)
Saccharomyces cerevisiae (Sce)	sce1665	YEL039C (S000000765)
Saccharomyces cerevisiae (Sce)	sce3543	YJR048W (S000003809)
Schizosaccharomyces pombe (Spo)	spo2613	SPCC191.07	P00046
Yarrowia lipolytica (Yli)	yli3096	YALI0D09273g

S. pombe systematic ID	S. cerevisiae systematic ID
SPCC191.07 (P00046)	YJR048W (S000003809)