Bahler Lab

Search term: YJR052W

Gene summary:

Species Saccharomyces cerevisiae (Sce)

Primary name RAD7

SGD link S000003813

Alternative ID YJR052W

Description Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex

Synonyms YJR052W

Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)

KOG1947 ACDHYP-

KOGs classification KOGs description

POORLY CHARACTERIZED Leucine rich repeat proteins, some proteins contain F-box

GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations

GO:0000108 repairosome C
IDA
Sce S000003813

GO:0000109 nucleotide-excision repair complex C
IPI
Spo SPCC330.02

GO:0000113 nucleotide-excision repair factor 4
complex C
IDA
Sce S000003813

GO:0000142 cellular bud neck contractile ring C
IDA
Sce S000003850

GO:0000151 ubiquitin ligase complex C
IDA
Ath At3g62980
ISS
Spo SPBC25B2.11
NAS
Hsa FBXL7
FBXL3
TAS
Hsa FBXL4

GO:0000152 nuclear ubiquitin ligase complex C
ISS
Dme FBgn0020257

GO:0005575 cellular_component C
ND
Ath At1g80630
At2g17020
At1g15740
At1g80570
At1g12820
At1g55590
At1g77000
At3g07550
At3g48880
At3g58530
At4g03630
At4g05470
At4g08980
At4g11580
At4g30640
At5g07670
At5g51370
At5g23340
At5g27920
At5g52480
At5g67140

GO:0005634 nucleus C
IDA
Ath At2g25490
At1g21410
At4g03190
At5g25350
Sce S000000362
S000003850
Spo SPCC330.02
TAS
Ath At2g25490
At5g25350

GO:0005737 cytoplasm C
IDA
Ath At3g50080
At5g67250
Sce S000000362
S000003850

GO:0005739 mitochondrion C
IDA
Spo SPBC25B2.11

GO:0005816 spindle pole body C
IDA
Spo SPCC330.02

GO:0005886 plasma membrane C
IDA
Ath At3g26810

GO:0005933 cellular bud C
IDA
Sce S000000362

GO:0019005 SCF ubiquitin ligase complex C
IDA
Ath At3g62980
At5g57900
IMP
Sce S000003850
IPI
Ath At2g39940
At1g21410
At5g25350
NAS
Dme FBgn0020257

GO:0031463 Cul3-RING ubiquitin ligase complex C
IDA
Sce S000003813

GO:0043224 nuclear SCF ubiquitin ligase complex C
IPI
Ath At4g03190

GO:0003674 molecular_function F
ND
Ath At3g48880
At4g03630
At5g07670
At5g51370
At5g40470
At5g52480
At5g51380

GO:0003684 damaged DNA binding F
IDA
Sce S000003813

GO:0004842 ubiquitin-protein ligase activity F
IC
Ath At3g62980
IDA
Sce S000003813
ISS
Ath At1g77000
At2g25490
At2g17020
At1g80570
At2g36370
At1g47056
At2g39940
At1g12820
At3g07550
At3g62980
At3g26810
At4g05470
At3g50080
At4g03190
At4g05490
At4g07400
At4g08980
At4g30640
At4g05460
At4g24390
At4g33210
At5g01720
At5g49980
At5g67250
At5g27920
NAS
Hsa FBXL7
FBXL3
TAS
Hsa FBXL6
Sce S000003850

GO:0005515 protein binding F
IPI
Ath At2g25490
At2g39940
At3g62980
At4g03190
At5g25350
At5g57900
Hsa FBXL7
KDM2A
Sce S000000362
Spo SPCC330.02
SPBC25B2.11
ISS
Ath At1g80630
At1g15740
TAS
Sce S000003850

GO:0008094 DNA-dependent ATPase activity F
IDA
Sce S000003813

GO:0010011 auxin binding F
IDA
Ath At3g62980
IGI
Ath At1g12820
At3g62980
At3g26810
At4g03190

GO:0030674 protein binding, bridging F
ISS
Spo SPBC25B2.11

GO:0000082 G1/S transition of mitotic cell
cycle P
TAS
Sce S000003850

GO:0000715 nucleotide-excision repair, DNA damage
recognition P
IDA
Sce S000003813
IMP
Sce S000003813

GO:0000751 cell cycle arrest in response to
pheromone P
IMP
Sce S000003850

GO:0001100 negative regulation of exit from
mitosis P
IGI
Sce S000000362
IMP
Sce S000000362

GO:0002237 response to molecule of bacterial
origin P
IEP
Ath At1g12820
At3g26810
At3g62980
At4g03190

GO:0006289 nucleotide-excision repair P
IGI
Spo SPCC330.02

GO:0006508 proteolysis P
TAS
Hsa FBXL6

GO:0006511 ubiquitin-dependent protein catabolic
process P
IGI
Ath At4g03190
ISS
Ath At5g01720
NAS
Dme FBgn0020257
Hsa FBXL7
TAS
Ath At2g17020
At1g77000
At2g36370
At2g39940
At1g80570
At2g25490
At3g07550
At3g50080
At3g62980
At4g03190
At4g07400
At4g05490
At4g05460
At4g05470
At4g08980
At4g24390
At4g30640
At4g33210
At5g01720
At5g25350
Hsa FBXL4

GO:0006952 defense response P
TAS
Ath At2g39940

GO:0006974 response to DNA damage stimulus P
IMP
Sce S000003850

GO:0007093 mitotic cell cycle checkpoint P
IMP
Sce S000000362

GO:0008150 biological_process P
ND
Ath At1g80630
At1g55590
At3g48880
At3g58530
At4g03630
At5g07670
At5g40470
At5g23340
At5g51370
At5g27920
At5g51380
At5g52480
At5g57900
Spo SPBC25B2.11

GO:0009611 response to wounding P
IMP
Ath At2g39940

GO:0009625 response to insect P
IMP
Ath At2g39940

GO:0009641 shade avoidance P
IMP
Ath At2g39940

GO:0009723 response to ethylene stimulus P
IMP
Ath At2g25490
At5g25350

GO:0009733 response to auxin stimulus P
IMP
Ath At3g62980
At4g03190

GO:0009753 response to jasmonic acid stimulus P
IMP
Ath At2g39940

GO:0009861 jasmonic acid and ethylene-dependent systemic
resistance P
TAS
Ath At2g39940

GO:0009867 jasmonic acid mediated signaling
pathway P
IGI
Ath At2g39940
TAS
Ath At2g39940

GO:0009909 regulation of flower development P
IMP
Ath At2g39940

GO:0010105 negative regulation of ethylene mediated signaling
pathway P
TAS
Ath At2g25490
At5g25350

GO:0010118 stomatal movement P
IMP
Ath At2g39940

GO:0010152 pollen maturation P
IGI
Ath At1g12820
At3g26810
At3g62980
At4g03190

GO:0010218 response to far red light P
IMP
Ath At2g39940

GO:0010252 auxin homeostasis P
IMP
Ath At4g33210

GO:0010286 heat acclimation P
IEP
Ath At1g77000

GO:0010311 lateral root formation P
IMP
Ath At3g62980

GO:0010608 posttranscriptional regulation of gene
expression P
IMP
Ath At4g08980

GO:0016036 cellular response to phosphate
starvation P
IEP
Ath At3g62980

GO:0016567 protein ubiquitination P
IGI
Sce S000003850
IPI
Sce S000003850
NAS
Hsa FBXL3

GO:0031146 SCF-dependent proteasomal ubiquitin-dependent
protein catabolic process P
IMP
Ath At2g39940
IPI
Ath At1g21410
Sce S000003850

GO:0031348 negative regulation of defense
response P
IMP
Ath At2g39940

GO:0034644 cellular response to UV P
IGI
Spo SPCC330.02

GO:0042742 defense response to bacterium P
IMP
Ath At2g39940

GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process P
IMP
Sce S000003813

GO:0045014 negative regulation of transcription by
glucose P
TAS
Ath At4g03190

GO:0048443 stamen development P
IGI
Ath At1g12820
At3g26810
At3g62980
At4g03190

GO:0048527 lateral root development P
IMP
Ath At1g12820

GO:0048589 developmental growth P
IGI
Ath At4g03190

GO:0048645 organ formation P
IMP
Ath At4g33210

GO:0050832 defense response to fungus P
IMP
Ath At2g39940

GO:0051603 proteolysis involved in cellular protein catabolic
process P
IMP
Ath At1g77000

GO:0051781 positive regulation of cell division P
IMP
Ath At1g21410

GO:0071249 cellular response to nitrate P
IEP
Ath At1g12820

GO:0080022 primary root development P
IMP
Ath At1g12820

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern

39455

Species Gene ID NCBI link UniProt link

Schizosaccharomyces pombe (Spo) rhp7
(SPCC330.02) GI:19075202 O74999

Saccharomyces cerevisiae (Sce) RAD7
(S000003813) GI:6322512 P06779

Kluyveromyces lactis (Kla) KLLA0A07997g GI:50302839

Eremothecium gossypii (Ego) AGOS_ACL088C GI:45185600

Magnaporthe grisea (Mgr) MGG_07015 GI:39978261

Neurospora crassa (Ncr) NCU03649.1 GI:32404676

GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations

GO:0000108 repairosome C
IDA
Sce S000003813

GO:0000109 nucleotide-excision repair complex C
IPI
Spo SPCC330.02

GO:0000113 nucleotide-excision repair factor 4
complex C
IDA
Sce S000003813

GO:0005634 nucleus C
IDA
Spo SPCC330.02

GO:0005816 spindle pole body C
IDA
Spo SPCC330.02

GO:0031463 Cul3-RING ubiquitin ligase complex C
IDA
Sce S000003813

GO:0003684 damaged DNA binding F
IDA
Sce S000003813

GO:0004842 ubiquitin-protein ligase activity F
IDA
Sce S000003813

GO:0005515 protein binding F
IPI
Spo SPCC330.02

GO:0008094 DNA-dependent ATPase activity F
IDA
Sce S000003813

GO:0000715 nucleotide-excision repair, DNA damage
recognition P
IDA
Sce S000003813
IMP
Sce S000003813

GO:0006289 nucleotide-excision repair P
IGI
Spo SPCC330.02

GO:0034644 cellular response to UV P
IGI
Spo SPCC330.02

GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process P
IMP
Sce S000003813

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern

OG1_9327

Species OrthoMCL
sequence Model organism
protein page UniProt link

Ashbya gossypii (Ago) ago961 ACL088C

Arabidopsis thaliana (Ath) ath7991 At2g06040.1

Arabidopsis thaliana (Ath) ath24414 At5g21900.1

Candida glabrata (Cgl) cgl914 CAGL0D06006g

Debaryomyces hansenii (Dha) dha867 DEHA0B04114g

Kluyveromyces lactis (Kla) kla353 KLLA0A07997g

Neurospora crassa (Ncr) ncr3540 NCU03649.2

Oryza sativa (Osa) osa26519 3938.m00160

Saccharomyces cerevisiae (Sce) sce3547 YJR052W
(S000003813)

Schizosaccharomyces pombe (Spo) spo4352 SPCC330.02 O74999

Yarrowia lipolytica (Yli) yli3592 YALI0D21208g

GO terms for OrthoMCL results:

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Curated yeast ortholog results:

S. pombe
systematic ID S. cerevisiae
systematic ID

SPCC330.02
(O74999) YJR052W
(S000003813)

GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations

GO:0000108 repairosome C
IDA
Sce S000003813

GO:0000109 nucleotide-excision repair complex C
IPI
Spo SPCC330.02

GO:0000113 nucleotide-excision repair factor 4
complex C
IDA
Sce S000003813

GO:0005634 nucleus C
IDA
Spo SPCC330.02

GO:0005816 spindle pole body C
IDA
Spo SPCC330.02

GO:0031463 Cul3-RING ubiquitin ligase complex C
IDA
Sce S000003813

GO:0003684 damaged DNA binding F
IDA
Sce S000003813

GO:0004842 ubiquitin-protein ligase activity F
IDA
Sce S000003813

GO:0005515 protein binding F
IPI
Spo SPCC330.02

GO:0008094 DNA-dependent ATPase activity F
IDA
Sce S000003813

GO:0000715 nucleotide-excision repair, DNA damage
recognition P
IDA
Sce S000003813
IMP
Sce S000003813

GO:0006289 nucleotide-excision repair P
IGI
Spo SPCC330.02

GO:0034644 cellular response to UV P
IGI
Spo SPCC330.02

GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process P
IMP
Sce S000003813

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YOGY Home

YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

s.khadayate@ucl.ac.uk

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG1947	ACDHYP-

KOGs classification	KOGs description
POORLY CHARACTERIZED	Leucine rich repeat proteins, some proteins contain F-box

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At1g12820	GI:18391439
Arabidopsis thaliana (Ath)	At1g15740	GI:15218289
Arabidopsis thaliana (Ath)	At1g21410	GI:18394987
Arabidopsis thaliana (Ath)	At1g47056	GI:15220130
Arabidopsis thaliana (Ath)	At1g55590	GI:15222749
Arabidopsis thaliana (Ath)	At1g77000	GI:18411319
Arabidopsis thaliana (Ath)	At1g80570	GI:18412871
Arabidopsis thaliana (Ath)	At1g80630	GI:18412879
Arabidopsis thaliana (Ath)	At2g06030	GI:15225041
Arabidopsis thaliana (Ath)	At2g17020	GI:18398283
Arabidopsis thaliana (Ath)	At2g25490	GI:18400846
Arabidopsis thaliana (Ath)	At2g36370	GI:15227644
Arabidopsis thaliana (Ath)	At2g39940	GI:18405209
Arabidopsis thaliana (Ath)	At3g07550	GI:18397984
Arabidopsis thaliana (Ath)	At3g26810	GI:18405102
Arabidopsis thaliana (Ath)	At3g48880	GI:15229043
Arabidopsis thaliana (Ath)	At3g50080	GI:18409012
Arabidopsis thaliana (Ath)	At3g58530	GI:11357437
Arabidopsis thaliana (Ath)	At3g62980	GI:18412567
Arabidopsis thaliana (Ath)	At4g03190	GI:18412177
Arabidopsis thaliana (Ath)	At4g03630	GI:15236356
Arabidopsis thaliana (Ath)	At4g05460	GI:18412947
Arabidopsis thaliana (Ath)	At4g05470	GI:7267307
Arabidopsis thaliana (Ath)	At4g05480	GI:7267308
Arabidopsis thaliana (Ath)	At4g05490	GI:18412951
Arabidopsis thaliana (Ath)	At4g05500	GI:18412953
Arabidopsis thaliana (Ath)	At4g07400	GI:18412996
Arabidopsis thaliana (Ath)	At4g08980	GI:18413178
Arabidopsis thaliana (Ath)	At4g11580	GI:15234238
Arabidopsis thaliana (Ath)	At4g15470_2	GI:7485070
Arabidopsis thaliana (Ath)	At4g24390	GI:18416337
Arabidopsis thaliana (Ath)	At4g30640	GI:18417634
Arabidopsis thaliana (Ath)	At4g33210	GI:7486446
Arabidopsis thaliana (Ath)	At5g01720	GI:11357830
Arabidopsis thaliana (Ath)	At5g07670	GI:15240836
Arabidopsis thaliana (Ath)	At5g23340	GI:15237286
Arabidopsis thaliana (Ath)	At5g25350	GI:15239399
Arabidopsis thaliana (Ath)	At5g27920	GI:18421172
Arabidopsis thaliana (Ath)	At5g40470	GI:15242713
Arabidopsis thaliana (Ath)	At5g49980	GI:18423092
Arabidopsis thaliana (Ath)	At5g51370	GI:15242063
Arabidopsis thaliana (Ath)	At5g51380	GI:15242066
Arabidopsis thaliana (Ath)	At5g52480	GI:15237166
Arabidopsis thaliana (Ath)	At5g57900	GI:18424042
Arabidopsis thaliana (Ath)	At5g67140	GI:15240225
Arabidopsis thaliana (Ath)	At5g67250	GI:18425169
Caenorhabditis elegans (Cel)	CE00856 (WBGene00007168)	GI:17551858	Q17492
Caenorhabditis elegans (Cel)	CE01883	GI:17532825
Caenorhabditis elegans (Cel)	CE02305	GI:17535889
Caenorhabditis elegans (Cel)	CE05180	GI:17538336
Caenorhabditis elegans (Cel)	CE05182 (WBGene00007208)	GI:17538340	Q17534
Caenorhabditis elegans (Cel)	CE27215 (WBGene00020884)	GI:17570119	Q968Y8
Caenorhabditis elegans (Cel)	CE27216	GI:17570117	Q968Y8
Caenorhabditis elegans (Cel)	CE28577 (WBGene00019294)	GI:17568607
Drosophila melanogaster (Dme)	7291460 (FBgn0020257)	GI:17647819
Drosophila melanogaster (Dme)	7292970	GI:7292970
Drosophila melanogaster (Dme)	7293460	GI:7293460
Drosophila melanogaster (Dme)	7294694	GI:7294694
Drosophila melanogaster (Dme)	7296905	GI:7296905
Drosophila melanogaster (Dme)	7298702	GI:20129655
Drosophila melanogaster (Dme)	7299136_2	GI:7299136
Drosophila melanogaster (Dme)	7299840	GI:7299840
Drosophila melanogaster (Dme)	7300083	GI:7300083
Drosophila melanogaster (Dme)	7300168	GI:7300168	Q8INB0
Drosophila melanogaster (Dme)	7301788	GI:7301788
Drosophila melanogaster (Dme)	7302418	GI:7302418	A1ZBR6
Drosophila melanogaster (Dme)	7303628	GI:7303628
Drosophila melanogaster (Dme)	7303992 (FBgn0033337)	GI:19921840
Homo sapiens (Hsa)	Hs13236573	GI:13236573
Homo sapiens (Hsa)	Hs16306576 (FBXL6)	GI:16306576	Q8N531
Homo sapiens (Hsa)	Hs16306578	GI:16306578
Homo sapiens (Hsa)	Hs16306580_2 (KDM2A)	GI:16306580	Q9Y2K7
Homo sapiens (Hsa)	Hs16306584_1 (FBXL3)	GI:16306584	Q9UKT7
Homo sapiens (Hsa)	Hs16306588 (FBXL4)	GI:16306588	Q9UKA2
Homo sapiens (Hsa)	Hs16306591	GI:16306591	Q8WV35
Homo sapiens (Hsa)	Hs18585373	GI:18585373
Homo sapiens (Hsa)	Hs20476897	GI:20476897
Homo sapiens (Hsa)	Hs21450771	GI:20543007
Homo sapiens (Hsa)	Hs22045361	GI:22045361
Homo sapiens (Hsa)	Hs22052495	GI:22052495
Homo sapiens (Hsa)	Hs22057112_2	GI:22057112
Homo sapiens (Hsa)	Hs22061735	GI:20381419	Q8N1E6
Homo sapiens (Hsa)	Hs22064590	GI:22064590
Homo sapiens (Hsa)	Hs22069605	GI:22069605
Homo sapiens (Hsa)	Hs6912466 (FBXL7)	GI:6912466	Q9UJT9
Homo sapiens (Hsa)	Hs8923179 (FBXL12)	GI:8923179	Q9NXK8
Saccharomyces cerevisiae (Sce)	YBR158w (S000000362)	GI:6319634	P38285
Saccharomyces cerevisiae (Sce)	YJR052w (S000003813)	GI:6322512	P06779
Saccharomyces cerevisiae (Sce)	YJR090c (S000003850)	GI:6322549	P24814
Schizosaccharomyces pombe (Spo)	SPBC25B2.11	GI:19112871	O74783
Schizosaccharomyces pombe (Spo)	SPCC330.02	GI:19075202	O74999

Species	Gene ID	NCBI link	UniProt link
Schizosaccharomyces pombe (Spo)	rhp7 (SPCC330.02)	GI:19075202	O74999
Saccharomyces cerevisiae (Sce)	RAD7 (S000003813)	GI:6322512	P06779
Kluyveromyces lactis (Kla)	KLLA0A07997g	GI:50302839
Eremothecium gossypii (Ego)	AGOS_ACL088C	GI:45185600
Magnaporthe grisea (Mgr)	MGG_07015	GI:39978261
Neurospora crassa (Ncr)	NCU03649.1	GI:32404676

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Ashbya gossypii (Ago)	ago961	ACL088C
Arabidopsis thaliana (Ath)	ath7991	At2g06040.1
Arabidopsis thaliana (Ath)	ath24414	At5g21900.1
Candida glabrata (Cgl)	cgl914	CAGL0D06006g
Debaryomyces hansenii (Dha)	dha867	DEHA0B04114g
Kluyveromyces lactis (Kla)	kla353	KLLA0A07997g
Neurospora crassa (Ncr)	ncr3540	NCU03649.2
Oryza sativa (Osa)	osa26519	3938.m00160
Saccharomyces cerevisiae (Sce)	sce3547	YJR052W (S000003813)
Schizosaccharomyces pombe (Spo)	spo4352	SPCC330.02	O74999
Yarrowia lipolytica (Yli)	yli3592	YALI0D21208g

S. pombe systematic ID	S. cerevisiae systematic ID
SPCC330.02 (O74999)	YJR052W (S000003813)