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Search term: YJR057W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CDC8
SGD link S000003818
Alternative ID YJR057W
Description Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p
Synonyms YJR057W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3327 ACDHYPE

KOGs classification KOGs description
METABOLISM Thymidylate kinase/adenylate kinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g59440 GI:15238421
Caenorhabditis elegans (Cel) CE03571
(WBGene00011272)		 GI:17535647 Q22018
Drosophila melanogaster (Dme) 7302676 GI:7302676
Homo sapiens (Hsa) Hs18550200 GI:18550200
Homo sapiens (Hsa) Hs22042064 GI:12804775 Q8WY85
Homo sapiens (Hsa) Hs6912340 GI:6912340
Saccharomyces cerevisiae (Sce) YJR057w
(S000003818)		 GI:6322517 P00572
Schizosaccharomyces pombe (Spo) SPCC70.07c GI:19076042 P36590
Encephalitozoon cuniculi (Ecu) ECU04g1220 GI:19074200 Q8SS22


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003818
SpoSPCC70.07c
GO:0005654 nucleoplasm C
IDA
AthAt5g59440
GO:0005737 cytoplasm C
IDA
AthAt5g59440
SceS000003818
GO:0005739 mitochondrion C
IDA
AthAt5g59440
GO:0005829 cytosol C
IDA
SpoSPCC70.07c
GO:0004798 thymidylate kinase activity F
IDA
SceS000003818
IGI
SpoSPCC70.07c
ISS
AthAt5g59440
GO:0005524 ATP binding F
ISS
SpoSPCC70.07c
GO:0009041 uridylate kinase activity F
IDA
SceS000003818
GO:0002119 nematode larval development P
IMP
CelWBGene00011272
GO:0006227 dUDP biosynthetic process P
IDA
SceS000003818
GO:0006233 dTDP biosynthetic process P
IDA
SceS000003818
GO:0006235 dTTP biosynthetic process P
IC
SpoSPCC70.07c
IDA
SceS000003818
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011272
GO:0040007 growth P
IMP
CelWBGene00011272
GO:0046939 nucleotide phosphorylation P
IGI
SpoSPCC70.07c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6285

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DTYMK GI:42544174
Pan troglodytes (Ptr) DTYMK GI:114584335
Mus musculus (Mmu) Dtymk
(MGI:108396)		 GI:12963517 P97930
Rattus norvegicus (Rno) Dtymk GI:109486376
Gallus gallus (Gga) RCJMB04_1b4 GI:118094933
Drosophila melanogaster (Dme) CG5757
(FBgn0034299)		 GI:28573735
Anopheles gambiae (Aga) AgaP_AGAP005260 GI:119113986
Caenorhabditis elegans (Cel) R53.2
(CE03571;
WBGene00011272)		 GI:17535647 Q22018
Schizosaccharomyces pombe (Spo) tmp GI:19076042
Saccharomyces cerevisiae (Sce) CDC8
(S000003818)		 GI:6322517 P00572
Kluyveromyces lactis (Kla) KLLA0B06556g GI:50303763
Magnaporthe grisea (Mgr) MGG_09457 GI:39960728
Neurospora crassa (Ncr) NCU07773.1 GI:32416002
Arabidopsis thaliana (Ath) ZEU1 GI:145334853
Oryza sativa (Osa) Os07g0639900 GI:115473639
Plasmodium falciparum (Pfa) PFL2465c GI:124807055


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPFL2465c
GO:0005634 nucleus C
IDA
SceS000003818
GO:0005654 nucleoplasm C
IDA
AthZEU1
GO:0005737 cytoplasm C
IDA
AthZEU1
SceS000003818
GO:0005739 mitochondrion C
IDA
AthZEU1
GO:0005829 cytosol C
EXP
HsaDTYMK
GO:0004798 thymidylate kinase activity F
IDA
HsaDTYMK
MmuMGI:108396
SceS000003818
ISO
MmuMGI:108396
ISS
AthZEU1
DmeFBgn0034299
GO:0009041 uridylate kinase activity F
IDA
SceS000003818
GO:0050145 nucleoside phosphate kinase activity F
EXP
HsaDTYMK
GO:0002119 nematode larval development P
IMP
CelWBGene00011272
GO:0006227 dUDP biosynthetic process P
IDA
SceS000003818
GO:0006233 dTDP biosynthetic process P
IDA
MmuMGI:108396
SceS000003818
GO:0006235 dTTP biosynthetic process P
IDA
SceS000003818
GO:0007049 cell cycle P
TAS
HsaDTYMK
GO:0008283 cell proliferation P
TAS
HsaDTYMK
GO:0009165 nucleotide biosynthetic process P
IDA
MmuMGI:108396
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011272
GO:0040007 growth P
IMP
CelWBGene00011272
GO:0046939 nucleotide phosphorylation P
IDA
MmuMGI:108396
ISO
MmuMGI:108396
GO:0071363 cellular response to growth factor
stimulus		 P
IDA
MmuMGI:108396

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_752

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga661 ENSANGP00000015825
Ashbya gossypii (Ago) ago3561 AFR369W
Arabidopsis thaliana (Ath) ath28011 At5g59440.1
Arabidopsis thaliana (Ath) ath28012 At5g59440.2
Caenorhabditis elegans (Cel) cel14121 R53.2
(CE03571;
WBGene00011272)
Candida glabrata (Cgl) cgl2148 CAGL0H01881g
Cryptococcus neoformans (Cne) cne5827 179.m00703
Dictyostelium discoideum (Ddi) ddi13042 DDB0230101
Debaryomyces hansenii (Dha) dha4880 DEHA0F11209g
Drosophila melanogaster (Dme) dme5778 CG5757-PA
(FBgn0034299)
Danio rerio (Dre) dre31486 ENSDARP00000015987
Escherichia coli (Eco) eco1062 16129061
Encephalitozoon cuniculi (Ecu) ecu838 19074200
Takifugu rubripes (Fru) fru8837 SINFRUP00000132545
Gallus gallus (Gga) gga23317 ENSGALP00000010180
(RCJMB04_1b4)
Homo sapiens (Hsa) hsa19606 ENSP00000304802
(DTYMK)		 P23919
Homo sapiens (Hsa) hsa21976 ENSP00000341279
Kluyveromyces lactis (Kla) kla825 KLLA0B06556g
Mus musculus (Mmu) mmu827 ENSMUSP00000027503
(MGI:108396)		 P97930-1
Neurospora crassa (Ncr) ncr7569 NCU07773.2
Oryza sativa (Osa) osa71107 6994.m00206
Plasmodium falciparum (Pfa) pfa5274 PFL2465c
Rattus norvegicus (Rno) rno30526 ENSRNOP00000025644
(RGD:1309614)
Saccharomyces cerevisiae (Sce) sce3552 YJR057W
(S000003818)
Schizosaccharomyces pombe (Spo) spo804 SPCC70.07c P36590
Yarrowia lipolytica (Yli) yli2260 YALI0C13354g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPFL2465c
GO:0005634 nucleus C
IDA
SceS000003818
SpoSPCC70.07c
GO:0005654 nucleoplasm C
IDA
AthAt5g59440
GO:0005737 cytoplasm C
IDA
AthAt5g59440
SceS000003818
GO:0005739 mitochondrion C
IDA
AthAt5g59440
GO:0005829 cytosol C
IDA
SpoSPCC70.07c
GO:0004798 thymidylate kinase activity F
IDA
MmuMGI:108396
SceS000003818
IGI
SpoSPCC70.07c
ISO
MmuMGI:108396
ISS
AthAt5g59440
DmeFBgn0034299
GO:0005524 ATP binding F
ISS
SpoSPCC70.07c
GO:0009041 uridylate kinase activity F
IDA
SceS000003818
GO:0002119 nematode larval development P
IMP
CelWBGene00011272
GO:0006227 dUDP biosynthetic process P
IDA
SceS000003818
GO:0006233 dTDP biosynthetic process P
IDA
MmuMGI:108396
SceS000003818
GO:0006235 dTTP biosynthetic process P
IC
SpoSPCC70.07c
IDA
SceS000003818
GO:0009165 nucleotide biosynthetic process P
IDA
MmuMGI:108396
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011272
GO:0040007 growth P
IMP
CelWBGene00011272
GO:0046939 nucleotide phosphorylation P
IDA
MmuMGI:108396
IGI
SpoSPCC70.07c
ISO
MmuMGI:108396
GO:0071363 cellular response to growth factor
stimulus		 P
IDA
MmuMGI:108396

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC70.07c
(P36590)		 YJR057W
(S000003818)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003818
SpoSPCC70.07c
GO:0005737 cytoplasm C
IDA
SceS000003818
GO:0005829 cytosol C
IDA
SpoSPCC70.07c
GO:0004798 thymidylate kinase activity F
IDA
SceS000003818
IGI
SpoSPCC70.07c
GO:0005524 ATP binding F
ISS
SpoSPCC70.07c
GO:0009041 uridylate kinase activity F
IDA
SceS000003818
GO:0006227 dUDP biosynthetic process P
IDA
SceS000003818
GO:0006233 dTDP biosynthetic process P
IDA
SceS000003818
GO:0006235 dTTP biosynthetic process P
IC
SpoSPCC70.07c
IDA
SceS000003818
GO:0046939 nucleotide phosphorylation P
IGI
SpoSPCC70.07c

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GO info in one table:

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