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Search term: YJR058C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name APS2
SGD link S000003819
Alternative ID YJR058C
Description Small subunit of the clathrin-associated adaptor complex AP-2, which is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex
Synonyms YJR058C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0935 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Clathrin adaptor complex, small subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g47830 GI:15220987
Caenorhabditis elegans (Cel) CE07018
(WBGene00000157)
GI:17551440 Q19123
Drosophila melanogaster (Dme) 7300728 GI:7300728
Homo sapiens (Hsa) Hs4757996 GI:4757996
Homo sapiens (Hsa) Hs11038643 GI:11038643 P53680
Saccharomyces cerevisiae (Sce) YJR058c
(S000003819)
GI:6322518 Q00381
Schizosaccharomyces pombe (Spo) SPBC685.04c GI:19112930 Q9Y7L6
Arabidopsis thaliana (Ath) At1g47830 GI:15220987
Caenorhabditis elegans (Cel) CE07018
(WBGene00000157)
GI:17551440 Q19123
Drosophila melanogaster (Dme) 7300728 GI:7300728
Homo sapiens (Hsa) Hs4757996 GI:4757996
Homo sapiens (Hsa) Hs11038643 GI:11038643 P53680
Saccharomyces cerevisiae (Sce) YJR058c
(S000003819)
GI:6322518 Q00381
Schizosaccharomyces pombe (Spo) SPBC685.04c GI:19112930 Q9Y7L6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005623 cell C
IDA
CelWBGene00000157
GO:0005634 nucleus C
IDA
SpoSPBC685.04c
GO:0005829 cytosol C
IDA
SpoSPBC685.04c
GO:0030122 AP-2 adaptor complex C
ISS
SceS000003819
SpoSPBC685.04c
GO:0030125 clathrin vesicle coat C
ISS
AthAt1g47830
GO:0003674 molecular_function F
ND
SceS000003819
GO:0030276 clathrin binding F
ISS
CelWBGene00000157
GO:0000003 reproduction P
IMP
CelWBGene00000157
RCA
SceS000003819
GO:0002119 nematode larval development P
IMP
CelWBGene00000157
GO:0006886 intracellular protein transport P
IC
SpoSPBC685.04c
ISS
AthAt1g47830
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00000157
GO:0010171 body morphogenesis P
IMP
CelWBGene00000157
GO:0016192 vesicle-mediated transport P
ISS
SceS000003819
SpoSPBC685.04c
TAS
SceS000003819
GO:0040007 growth P
IMP
CelWBGene00000157
GO:0051301 cell division P
RCA
SceS000003819

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3001

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) AP2S1 GI:70906430
Pan troglodytes (Ptr) AP2S1 GI:55649469
Canis familiaris (Cfa) AP2S1 GI:57036403
Mus musculus (Mmu) Ap2s1
(MGI:2141861)
GI:38348472 P62743
Rattus norvegicus (Rno) Ap2s1
(RGD:620188)
GI:56961624
Drosophila melanogaster (Dme) AP-2sigma GI:24648686
Anopheles gambiae (Aga) AgaP_AGAP001703 GI:158301732
Caenorhabditis elegans (Cel) aps-2
(CE07018;
WBGene00000157)
GI:17551440 Q19123
Schizosaccharomyces pombe (Spo) aps2
(SPBC685.04c)
GI:19112930 Q9Y7L6
Saccharomyces cerevisiae (Sce) APS2
(S000003819)
GI:6322518 Q00381
Kluyveromyces lactis (Kla) KLLA0B06545g GI:50303761
Eremothecium gossypii (Ego) AGOS_AFR370C GI:45198888
Magnaporthe grisea (Mgr) MGG_01762 GI:39952239
Neurospora crassa (Ncr) NCU07989.1 GI:32416434
Arabidopsis thaliana (Ath) AT1G47830 GI:15220987
Oryza sativa (Osa) Os12g0207300 GI:115487800


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005623 cell C
IDA
CelWBGene00000157
GO:0005634 nucleus C
IDA
SpoSPBC685.04c
GO:0005829 cytosol C
EXP
HsaAP2S1
IDA
SpoSPBC685.04c
GO:0005886 plasma membrane C
EXP
HsaAP2S1
GO:0008021 synaptic vesicle C
TAS
DmeAP-2sigma
GO:0030122 AP-2 adaptor complex C
ISO
MmuMGI:2141861
ISS
SceS000003819
SpoSPBC685.04c
TAS
HsaAP2S1
GO:0030125 clathrin vesicle coat C
ISS
AthAt1g47830
GO:0030135 coated vesicle C
TAS
DmeAP-2sigma
GO:0030666 endocytic vesicle membrane C
EXP
HsaAP2S1
GO:0003674 molecular_function F
ND
MmuMGI:2141861
SceS000003819
GO:0005215 transporter activity F
NAS
HsaAP2S1
GO:0008565 protein transporter activity F
NAS
HsaAP2S1
GO:0030276 clathrin binding F
ISS
CelWBGene00000157
GO:0000003 reproduction P
IMP
CelWBGene00000157
RCA
SceS000003819
GO:0002119 nematode larval development P
IMP
CelWBGene00000157
GO:0006886 intracellular protein transport P
IC
SpoSPBC685.04c
ISS
AthAt1g47830
GO:0006901 vesicle coating P
TAS
DmeAP-2sigma
GO:0007269 neurotransmitter secretion P
NAS
DmeAP-2sigma
GO:0008150 biological_process P
ND
MmuMGI:2141861
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00000157
GO:0010171 body morphogenesis P
IMP
CelWBGene00000157
GO:0016183 synaptic vesicle coating P
TAS
DmeAP-2sigma
GO:0016192 vesicle-mediated transport P
ISS
SceS000003819
SpoSPBC685.04c
TAS
SceS000003819
GO:0030100 regulation of endocytosis P
TAS
HsaAP2S1
GO:0040007 growth P
IMP
CelWBGene00000157
GO:0048268 clathrin coat assembly P
TAS
HsaAP2S1
GO:0050690 regulation of defense response to virus by
virus
P
EXP
HsaAP2S1
GO:0051301 cell division P
RCA
SceS000003819

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3596

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga3818 ENSANGP00000008517
Ashbya gossypii (Ago) ago3562 AFR370C
Arabidopsis thaliana (Ath) ath4046 At1g47830.1
Caenorhabditis elegans (Cel) cel5460 F02E8.3
(CE07018;
WBGene00000157)
Candida glabrata (Cgl) cgl2147 CAGL0H01859g
Cryptococcus neoformans (Cne) cne2874 183.m01883
Dictyostelium discoideum (Ddi) ddi9650 DDB0188542
Debaryomyces hansenii (Dha) dha4879 DEHA0F11187g
Drosophila melanogaster (Dme) dme13667 CG6056-PA
(FBgn0043012)
Danio rerio (Dre) dre25143 ENSDARP00000031559
(zgc:65827)
Q6PEJ2
Takifugu rubripes (Fru) fru13521 SINFRUP00000130860
Gallus gallus (Gga) gga24358 ENSGALP00000000595
Homo sapiens (Hsa) hsa16690 ENSP00000263270
(AP2S1)
P53680-1
Kluyveromyces lactis (Kla) kla824 KLLA0B06545g
Mus musculus (Mmu) mmu23201 ENSMUSP00000008180
Neurospora crassa (Ncr) ncr7781 NCU07989.2
Oryza sativa (Osa) osa1714 1892.m00152
Oryza sativa (Osa) osa59670 6528.m00149
Rattus norvegicus (Rno) rno1122 ENSRNOP00000021310
(RGD:620188)
P62744
Saccharomyces cerevisiae (Sce) sce3553 YJR058C
(S000003819)
Schizosaccharomyces pombe (Spo) spo3725 SPBC685.04c Q9Y7L6
Yarrowia lipolytica (Yli) yli915 YALI0B04246g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005623 cell C
IDA
CelWBGene00000157
GO:0005634 nucleus C
IDA
SpoSPBC685.04c
GO:0005829 cytosol C
IDA
SpoSPBC685.04c
GO:0008021 synaptic vesicle C
TAS
DmeFBgn0043012
GO:0030122 AP-2 adaptor complex C
ISS
SceS000003819
SpoSPBC685.04c
GO:0030125 clathrin vesicle coat C
ISS
AthAt1g47830
GO:0030135 coated vesicle C
TAS
DmeFBgn0043012
GO:0003674 molecular_function F
ND
SceS000003819
GO:0030276 clathrin binding F
ISS
CelWBGene00000157
GO:0000003 reproduction P
IMP
CelWBGene00000157
RCA
SceS000003819
GO:0002119 nematode larval development P
IMP
CelWBGene00000157
GO:0006886 intracellular protein transport P
IC
SpoSPBC685.04c
ISS
AthAt1g47830
GO:0006901 vesicle coating P
TAS
DmeFBgn0043012
GO:0007269 neurotransmitter secretion P
NAS
DmeFBgn0043012
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00000157
GO:0010171 body morphogenesis P
IMP
CelWBGene00000157
GO:0016183 synaptic vesicle coating P
TAS
DmeFBgn0043012
GO:0016192 vesicle-mediated transport P
ISS
SceS000003819
SpoSPBC685.04c
TAS
SceS000003819
GO:0040007 growth P
IMP
CelWBGene00000157
GO:0051301 cell division P
RCA
SceS000003819

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC685.04c
(Q9Y7L6)
YJR058C
(S000003819)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC685.04c
GO:0005829 cytosol C
IDA
SpoSPBC685.04c
GO:0030122 AP-2 adaptor complex C
ISS
SceS000003819
SpoSPBC685.04c
GO:0003674 molecular_function F
ND
SceS000003819
GO:0000003 reproduction P
RCA
SceS000003819
GO:0006886 intracellular protein transport P
IC
SpoSPBC685.04c
GO:0016192 vesicle-mediated transport P
ISS
SceS000003819
SpoSPBC685.04c
TAS
SceS000003819
GO:0051301 cell division P
RCA
SceS000003819

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Search for gene by ID or name:

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GO info in one table:

s.khadayate@ucl.ac.uk