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Search term: YJR068W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RFC2
SGD link S000003829
Alternative ID YJR068W
Description Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
Synonyms YJR068W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0989 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Replication factor C, subunit RFC4

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g14460 GI:15223761
Arabidopsis thaliana (Ath) At1g21690 GI:15219065
Arabidopsis thaliana (Ath) At2g02480 GI:7484925
Arabidopsis thaliana (Ath) At4g18820 GI:15234039
Arabidopsis thaliana (Ath) At4g24790 GI:15233988
Arabidopsis thaliana (Ath) At5g45720 GI:15242480
Caenorhabditis elegans (Cel) CE01268
(WBGene00004340)		 GI:17554730 P53016
Drosophila melanogaster (Dme) 7293390 GI:7293390
Homo sapiens (Hsa) Hs4506491
(RFC4)		 GI:4506491 P35249
Saccharomyces cerevisiae (Sce) YJR068w
(S000003829)		 GI:6322528 P40348
Schizosaccharomyces pombe (Spo) SPAC23D3.02 GI:19115452 Q09843
Encephalitozoon cuniculi (Ecu) ECU02g0680 GI:19073988 Q8SSG6
Arabidopsis thaliana (Ath) At1g14460 GI:15223761
Arabidopsis thaliana (Ath) At1g21690 GI:15219065
Arabidopsis thaliana (Ath) At2g02480 GI:7484925
Arabidopsis thaliana (Ath) At4g18820 GI:15234039
Arabidopsis thaliana (Ath) At4g24790 GI:15233988
Arabidopsis thaliana (Ath) At5g45720 GI:15242480
Caenorhabditis elegans (Cel) CE01268
(WBGene00004340)		 GI:17554730 P53016
Drosophila melanogaster (Dme) 7293390 GI:7293390
Homo sapiens (Hsa) Hs4506491
(RFC4)		 GI:4506491 P35249
Saccharomyces cerevisiae (Sce) YJR068w
(S000003829)		 GI:6322528 P40348
Schizosaccharomyces pombe (Spo) SPAC23D3.02 GI:19115452 Q09843
Encephalitozoon cuniculi (Ecu) ECU02g0680 GI:19073988 Q8SSG6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPAC23D3.02
GO:0005634 nucleus C
IDA
SpoSPAC23D3.02
GO:0005654 nucleoplasm C
EXP
HsaRFC4
GO:0005663 DNA replication factor C complex C
IDA
HsaRFC4
SceS000003829
ISS
AthAt1g21690
SpoSPAC23D3.02
GO:0005730 nucleolus C
IDA
AthAt1g21690
GO:0005829 cytosol C
IDA
SpoSPAC23D3.02
GO:0005886 plasma membrane C
IDA
AthAt2g02480
At4g18820
At1g14460
GO:0031389 Rad17 RFC-like complex C
IDA
SceS000003829
TAS
SpoSPAC23D3.02
GO:0031390 Ctf18 RFC-like complex C
IPI
SceS000003829
TAS
SpoSPAC23D3.02
GO:0031391 Elg1 RFC-like complex C
IDA
SpoSPAC23D3.02
IPI
SceS000003829
GO:0043596 nuclear replication fork C
IC
SpoSPAC23D3.02
GO:0003689 DNA clamp loader activity F
IDA
SceS000003829
TAS
SpoSPAC23D3.02
GO:0005515 protein binding F
IPI
HsaRFC4
GO:0016887 ATPase activity F
ISS
AthAt1g21690
GO:0017076 purine nucleotide binding F
ISS
SceS000003829
GO:0000003 reproduction P
IMP
CelWBGene00004340
GO:0000075 cell cycle checkpoint P
IMP
SceS000003829
GO:0000076 DNA replication checkpoint P
IMP
SpoSPAC23D3.02
GO:0000910 cytokinesis P
IMP
CelWBGene00004340
GO:0006260 DNA replication P
EXP
HsaRFC4
NAS
HsaRFC4
GO:0006270 DNA-dependent DNA replication initiation P
IMP
SpoSPAC23D3.02
GO:0006271 DNA strand elongation involved in DNA
replication		 P
TAS
HsaRFC4
GO:0006272 leading strand elongation P
IDA
SceS000003829
GO:0006281 DNA repair P
NAS
HsaRFC4
GO:0006297 nucleotide-excision repair, DNA gap
filling		 P
EXP
HsaRFC4
GO:0006298 mismatch repair P
TAS
SceS000003829
GO:0007062 sister chromatid cohesion P
IPI
SceS000003829
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004340
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt1g21690
GO:0010026 trichome differentiation P
IMP
AthAt2g02480
GO:0010091 trichome branching P
IMP
AthAt2g02480
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004340
GO:0045750 positive regulation of S phase of mitotic cell
cycle		 P
IMP
CelWBGene00004340
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaRFC4
GO:0051301 cell division P
IMP
CelWBGene00004340

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6288

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) RFC4 GI:4506491 P35249
Canis familiaris (Cfa) RFC4 GI:57109940
Mus musculus (Mmu) Rfc4
(MGI:2146571)		 GI:21703948 Q3UI84
Rattus norvegicus (Rno) Rfc4 GI:62658068
Gallus gallus (Gga) RFC4 GI:57529590
Drosophila melanogaster (Dme) CG8142
(FBgn0030871)		 GI:18859927
Anopheles gambiae (Aga) AgaP_AGAP003093 GI:118783134
Schizosaccharomyces pombe (Spo) rfc2
(SPAC23D3.02)		 GI:19115452 Q09843
Saccharomyces cerevisiae (Sce) RFC2
(S000003829)		 GI:6322528 P40348
Kluyveromyces lactis (Kla) KLLA0B13992g GI:50304409
Eremothecium gossypii (Ego) AGOS_AFR422W GI:45198940
Magnaporthe grisea (Mgr) MGG_04389 GI:145614662
Neurospora crassa (Ncr) NCU02687.1 GI:32422885
Arabidopsis thaliana (Ath) emb1968 GI:18395021
Oryza sativa (Osa) Os12g0176500 GI:115487618
Plasmodium falciparum (Pfa) PFB0840w GI:124801405


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPAC23D3.02
GO:0005575 cellular_component C
ND
MmuMGI:2146571
GO:0005634 nucleus C
IDA
SpoSPAC23D3.02
GO:0005654 nucleoplasm C
EXP
HsaRFC4
GO:0005663 DNA replication factor C complex C
IDA
HsaRFC4
SceS000003829
ISS
Athemb1968
DmeFBgn0030871
PfaPFB0840w
SpoSPAC23D3.02
GO:0005730 nucleolus C
IDA
Athemb1968
GO:0005829 cytosol C
IDA
SpoSPAC23D3.02
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0030871
GO:0031389 Rad17 RFC-like complex C
IDA
SceS000003829
TAS
SpoSPAC23D3.02
GO:0031390 Ctf18 RFC-like complex C
IPI
SceS000003829
TAS
SpoSPAC23D3.02
GO:0031391 Elg1 RFC-like complex C
IDA
SpoSPAC23D3.02
IPI
SceS000003829
GO:0043596 nuclear replication fork C
IC
SpoSPAC23D3.02
GO:0003674 molecular_function F
ND
MmuMGI:2146571
GO:0003677 DNA binding F
ISS
DmeFBgn0030871
GO:0003689 DNA clamp loader activity F
IDA
SceS000003829
TAS
SpoSPAC23D3.02
GO:0005515 protein binding F
IPI
HsaRFC4
GO:0016887 ATPase activity F
ISS
Athemb1968
GO:0017076 purine nucleotide binding F
ISS
SceS000003829
GO:0000075 cell cycle checkpoint P
IMP
SceS000003829
GO:0000076 DNA replication checkpoint P
IMP
SpoSPAC23D3.02
GO:0006260 DNA replication P
EXP
HsaRFC4
ISS
DmeFBgn0030871
PfaPFB0840w
NAS
HsaRFC4
GO:0006270 DNA-dependent DNA replication initiation P
IMP
SpoSPAC23D3.02
GO:0006271 DNA strand elongation involved in DNA
replication		 P
TAS
HsaRFC4
GO:0006272 leading strand elongation P
IDA
SceS000003829
GO:0006281 DNA repair P
NAS
HsaRFC4
GO:0006297 nucleotide-excision repair, DNA gap
filling		 P
EXP
HsaRFC4
GO:0006298 mismatch repair P
TAS
SceS000003829
GO:0007062 sister chromatid cohesion P
IPI
SceS000003829
GO:0008150 biological_process P
ND
MmuMGI:2146571
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
Athemb1968
GO:0031122 cytoplasmic microtubule organization P
IMP
DmeFBgn0030871
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaRFC4

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2523

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5377 ENSANGP00000020452
Ashbya gossypii (Ago) ago3614 AFR422W
Arabidopsis thaliana (Ath) ath2325 At1g21690.1
Arabidopsis thaliana (Ath) ath2326 At1g21690.2
Caenorhabditis elegans (Cel) cel7786 F31E3.3
(CE01268;
WBGene00004340)
Candida glabrata (Cgl) cgl1251 CAGL0F00451g
Dictyostelium discoideum (Ddi) ddi8569 DDB0186776
Debaryomyces hansenii (Dha) dha5160 DEHA0F17336g
Drosophila melanogaster (Dme) dme18385 CG8142-PA
(FBgn0030871)
Danio rerio (Dre) dre26253 ENSDARP00000023842
Takifugu rubripes (Fru) fru4862 SINFRUP00000156214
Gallus gallus (Gga) gga23616 ENSGALP00000014146
(RFC4)		 Q5ZHL1
Homo sapiens (Hsa) hsa23596 ENSP00000296273
(RFC4)		 P35249
Kluyveromyces lactis (Kla) kla1152 KLLA0B13992g
Mus musculus (Mmu) mmu10135 ENSMUSP00000023598
(MGI:2146571)		 Q99J62
Neurospora crassa (Ncr) ncr2603 NCU02687.2
Oryza sativa (Osa) osa1674 1890.m00146
Oryza sativa (Osa) osa69363 7075.m00130
Plasmodium falciparum (Pfa) pfa121 PFB0840w
Rattus norvegicus (Rno) rno7522 ENSRNOP00000002487
(RGD:1310142)		 B4F778
Saccharomyces cerevisiae (Sce) sce3563 YJR068W
(S000003829)
Schizosaccharomyces pombe (Spo) spo1722 SPAC23D3.02 Q09843
Yarrowia lipolytica (Yli) yli4307 YALI0E10747g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPAC23D3.02
GO:0005575 cellular_component C
ND
MmuMGI:2146571
GO:0005634 nucleus C
IDA
SpoSPAC23D3.02
GO:0005663 DNA replication factor C complex C
IDA
SceS000003829
ISS
AthAt1g21690
DmeFBgn0030871
PfaPFB0840w
SpoSPAC23D3.02
GO:0005730 nucleolus C
IDA
AthAt1g21690
GO:0005829 cytosol C
IDA
SpoSPAC23D3.02
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0030871
GO:0031389 Rad17 RFC-like complex C
IDA
SceS000003829
TAS
SpoSPAC23D3.02
GO:0031390 Ctf18 RFC-like complex C
IPI
SceS000003829
TAS
SpoSPAC23D3.02
GO:0031391 Elg1 RFC-like complex C
IDA
SpoSPAC23D3.02
IPI
SceS000003829
GO:0043596 nuclear replication fork C
IC
SpoSPAC23D3.02
GO:0003674 molecular_function F
ND
MmuMGI:2146571
GO:0003677 DNA binding F
ISS
DmeFBgn0030871
GO:0003689 DNA clamp loader activity F
IDA
SceS000003829
TAS
SpoSPAC23D3.02
GO:0016887 ATPase activity F
ISS
AthAt1g21690
GO:0017076 purine nucleotide binding F
ISS
SceS000003829
GO:0000003 reproduction P
IMP
CelWBGene00004340
GO:0000075 cell cycle checkpoint P
IMP
SceS000003829
GO:0000076 DNA replication checkpoint P
IMP
SpoSPAC23D3.02
GO:0000910 cytokinesis P
IMP
CelWBGene00004340
GO:0006260 DNA replication P
ISS
DmeFBgn0030871
PfaPFB0840w
GO:0006270 DNA-dependent DNA replication initiation P
IMP
SpoSPAC23D3.02
GO:0006272 leading strand elongation P
IDA
SceS000003829
GO:0006298 mismatch repair P
TAS
SceS000003829
GO:0007062 sister chromatid cohesion P
IPI
SceS000003829
GO:0008150 biological_process P
ND
MmuMGI:2146571
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004340
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt1g21690
GO:0031122 cytoplasmic microtubule organization P
IMP
DmeFBgn0030871
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00004340
GO:0045750 positive regulation of S phase of mitotic cell
cycle		 P
IMP
CelWBGene00004340
GO:0051301 cell division P
IMP
CelWBGene00004340

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC23D3.02
(Q09843)		 YJR068W
(S000003829)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPAC23D3.02
GO:0005634 nucleus C
IDA
SpoSPAC23D3.02
GO:0005663 DNA replication factor C complex C
IDA
SceS000003829
ISS
SpoSPAC23D3.02
GO:0005829 cytosol C
IDA
SpoSPAC23D3.02
GO:0031389 Rad17 RFC-like complex C
IDA
SceS000003829
TAS
SpoSPAC23D3.02
GO:0031390 Ctf18 RFC-like complex C
IPI
SceS000003829
TAS
SpoSPAC23D3.02
GO:0031391 Elg1 RFC-like complex C
IDA
SpoSPAC23D3.02
IPI
SceS000003829
GO:0043596 nuclear replication fork C
IC
SpoSPAC23D3.02
GO:0003689 DNA clamp loader activity F
IDA
SceS000003829
TAS
SpoSPAC23D3.02
GO:0017076 purine nucleotide binding F
ISS
SceS000003829
GO:0000075 cell cycle checkpoint P
IMP
SceS000003829
GO:0000076 DNA replication checkpoint P
IMP
SpoSPAC23D3.02
GO:0006270 DNA-dependent DNA replication initiation P
IMP
SpoSPAC23D3.02
GO:0006272 leading strand elongation P
IDA
SceS000003829
GO:0006298 mismatch repair P
TAS
SceS000003829
GO:0007062 sister chromatid cohesion P
IPI
SceS000003829

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