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Search term: YJR070C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name LIA1
SGD link S000003831
Alternative ID YJR070C
Description Deoxyhypusine hydroxylase, a HEAT-repeat containing metalloenzyme that catalyzes hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning
Synonyms YJR070C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0567 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED HEAT repeat-containing protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g43260 GI:15229250
Arabidopsis thaliana (Ath) At3g58180 GI:11281934
Arabidopsis thaliana (Ath) At3g62530_2 GI:11357981
Caenorhabditis elegans (Cel) CE02138
(WBGene00007555)		 GI:17531753 Q17949
Drosophila melanogaster (Dme) 7302088 GI:7302088
Homo sapiens (Hsa) Hs13775228 GI:13775228 Q9BU89
Saccharomyces cerevisiae (Sce) YJR070c
(S000003831)		 GI:6322531 P47120
Schizosaccharomyces pombe (Spo) SPAC30C2.02 GI:19115566 Q9P6K9
Encephalitozoon cuniculi (Ecu) ECU06g1490 GI:19074400 Q8SV71
Arabidopsis thaliana (Ath) At3g43260 GI:15229250
Arabidopsis thaliana (Ath) At3g58180 GI:11281934
Arabidopsis thaliana (Ath) At3g62530_2 GI:11357981
Caenorhabditis elegans (Cel) CE02138
(WBGene00007555)		 GI:17531753 Q17949
Drosophila melanogaster (Dme) 7302088 GI:7302088
Homo sapiens (Hsa) Hs13775228 GI:13775228 Q9BU89
Saccharomyces cerevisiae (Sce) YJR070c
(S000003831)		 GI:6322531 P47120
Schizosaccharomyces pombe (Spo) SPAC30C2.02 GI:19115566 Q9P6K9
Encephalitozoon cuniculi (Ecu) ECU06g1490 GI:19074400 Q8SV71


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g43260
GO:0005634 nucleus C
IDA
SceS000003831
SpoSPAC30C2.02
GO:0005730 nucleolus C
IDA
AthAt3g62530
GO:0005737 cytoplasm C
IDA
SceS000003831
SpoSPAC30C2.02
GO:0005739 mitochondrion C
IDA
AthAt3g62530
GO:0005829 cytosol C
IDA
SpoSPAC30C2.02
GO:0009507 chloroplast C
IDA
AthAt3g62530
GO:0030089 phycobilisome C
ISS
AthAt3g62530
At3g58180
GO:0003674 molecular_function F
ND
AthAt3g43260
GO:0008270 zinc ion binding F
IDA
AthAt3g62530
GO:0016829 lyase activity F
ISS
AthAt3g62530
At3g58180
GO:0019135 deoxyhypusine monooxygenase activity F
IDA
SceS000003831
IMP
SceS000003831
ISS
SpoSPAC30C2.02
GO:0046872 metal ion binding F
IDA
AthAt3g62530
GO:0000226 microtubule cytoskeleton organization P
IGI
SceS000003831
IMP
SceS000003831
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00007555
GO:0007018 microtubule-based movement P
IMP
SpoSPAC30C2.02
GO:0008150 biological_process P
ND
AthAt3g62530
At3g58180
At3g43260
GO:0008612 peptidyl-lysine modification to
hypusine		 P
IC
SpoSPAC30C2.02
IDA
SceS000003831
IMP
SceS000003831
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00007555
GO:0010171 body morphogenesis P
IMP
CelWBGene00007555
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000003831
GO:0019915 lipid storage P
IMP
CelWBGene00007555
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007555
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00007555
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000003831
GO:0048311 mitochondrion distribution P
IGI
SpoSPAC30C2.02

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6290

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DOHH GI:223633884
Pan troglodytes (Ptr) DOHH GI:114674622
Canis familiaris (Cfa) DOHH GI:73987463
Mus musculus (Mmu) Dohh
(MGI:1915964)		 GI:19527182 Q99LN9
Rattus norvegicus (Rno) Dohh GI:68163445
Gallus gallus (Gga) DOHH GI:118120493
Drosophila melanogaster (Dme) l(3)s1921
(FBgn0011013)		 GI:24651728
Anopheles gambiae (Aga) AgaP_AGAP002129 GI:118793530
Caenorhabditis elegans (Cel) tag-242
(CE02138;
WBGene00007555)		 GI:17531753 Q17949
Schizosaccharomyces pombe (Spo) mmd1
(SPAC30C2.02)		 GI:19115566 Q9P6K9
Saccharomyces cerevisiae (Sce) LIA1
(S000003831)		 GI:6322531 P47120
Kluyveromyces lactis (Kla) KLLA0B14080g GI:50304417
Eremothecium gossypii (Ego) AGOS_AFR426C GI:45198944
Magnaporthe grisea (Mgr) MGG_01725 GI:145613339
Neurospora crassa (Ncr) NCU05252.1 GI:32408255
Arabidopsis thaliana (Ath) AT3G58180 GI:18410896
Oryza sativa (Osa) Os12g0626100 GI:115489670
Oryza sativa (Osa) Os12g0163300 GI:115487484
Plasmodium falciparum (Pfa) PF13_0013 GI:124512794


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
HsaDOHH
MmuMGI:1915964
PfaPF13_0013
GO:0005634 nucleus C
IDA
SceS000003831
SpoSPAC30C2.02
GO:0005737 cytoplasm C
IDA
SceS000003831
SpoSPAC30C2.02
GO:0005829 cytosol C
IDA
SpoSPAC30C2.02
GO:0030089 phycobilisome C
ISS
AthAt3g58180
GO:0003674 molecular_function F
ND
MmuMGI:1915964
GO:0005515 protein binding F
IPI
HsaDOHH
GO:0016829 lyase activity F
ISS
AthAt3g58180
GO:0019135 deoxyhypusine monooxygenase activity F
IDA
SceS000003831
IMP
HsaDOHH
SceS000003831
ISS
SpoSPAC30C2.02
GO:0000226 microtubule cytoskeleton organization P
IGI
SceS000003831
IMP
SceS000003831
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00007555
GO:0007018 microtubule-based movement P
IMP
SpoSPAC30C2.02
GO:0008150 biological_process P
ND
AthAt3g58180
MmuMGI:1915964
PfaPF13_0013
GO:0008612 peptidyl-lysine modification to
hypusine		 P
EXP
HsaDOHH
IC
SpoSPAC30C2.02
IDA
SceS000003831
IMP
HsaDOHH
SceS000003831
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00007555
GO:0010171 body morphogenesis P
IMP
CelWBGene00007555
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000003831
GO:0019915 lipid storage P
IMP
CelWBGene00007555
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007555
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00007555
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000003831
GO:0048311 mitochondrion distribution P
IGI
SpoSPAC30C2.02

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2271

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4252 ENSANGP00000017698
Ashbya gossypii (Ago) ago3618 AFR426C
Arabidopsis thaliana (Ath) ath17223 At3g58180.1
Caenorhabditis elegans (Cel) cel1919 C14A4.1
(CE02138;
WBGene00007555)
Candida glabrata (Cgl) cgl1249 CAGL0F00407g
Dictyostelium discoideum (Ddi) ddi3633 DDB0167948
Dictyostelium discoideum (Ddi) ddi3800 DDB0217452
Debaryomyces hansenii (Dha) dha5500 DEHA0F24948g
Drosophila melanogaster (Dme) dme15425 CG2245-PA
(FBgn0011013)
Danio rerio (Dre) dre22614 ENSDARP00000011317
(dohh)		 Q7ZUX6
Encephalitozoon cuniculi (Ecu) ecu1627 19074400
Takifugu rubripes (Fru) fru20299 SINFRUP00000132131
Gallus gallus (Gga) gga25008 ENSGALP00000028167
(DOHH)		 Q5ZIP3
Homo sapiens (Hsa) hsa15312 ENSP00000250937
(DOHH)		 Q9BU89
Kluyveromyces lactis (Kla) kla1156 KLLA0B14080g
Mus musculus (Mmu) mmu2581 ENSMUSP00000020458
Mus musculus (Mmu) mmu2582 ENSMUSP00000072534
(MGI:1915964)		 Q99LN9-1
Neurospora crassa (Ncr) ncr5097 NCU05252.2
Oryza sativa (Osa) osa36589 4939.m00073
Oryza sativa (Osa) osa69209 7071.m00104
Plasmodium falciparum (Pfa) pfa4082 PF13_0013
Rattus norvegicus (Rno) rno26188 ENSRNOP00000005640
(RGD:1304783)		 Q5PPJ4
Saccharomyces cerevisiae (Sce) sce3565 YJR070C
(S000003831)
Schizosaccharomyces pombe (Spo) spo1383 SPAC30C2.02 Q9P6K9
Yarrowia lipolytica (Yli) yli268 YALI0A08129g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1915964
PfaPF13_0013
GO:0005634 nucleus C
IDA
SceS000003831
SpoSPAC30C2.02
GO:0005737 cytoplasm C
IDA
SceS000003831
SpoSPAC30C2.02
GO:0005829 cytosol C
IDA
SpoSPAC30C2.02
GO:0030089 phycobilisome C
ISS
AthAt3g58180
GO:0003674 molecular_function F
ND
MmuMGI:1915964
GO:0016829 lyase activity F
ISS
AthAt3g58180
GO:0019135 deoxyhypusine monooxygenase activity F
IDA
SceS000003831
IMP
SceS000003831
ISS
SpoSPAC30C2.02
GO:0000226 microtubule cytoskeleton organization P
IGI
SceS000003831
IMP
SceS000003831
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00007555
GO:0007018 microtubule-based movement P
IMP
SpoSPAC30C2.02
GO:0008150 biological_process P
ND
AthAt3g58180
MmuMGI:1915964
PfaPF13_0013
GO:0008612 peptidyl-lysine modification to
hypusine		 P
IC
SpoSPAC30C2.02
IDA
SceS000003831
IMP
SceS000003831
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00007555
GO:0010171 body morphogenesis P
IMP
CelWBGene00007555
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000003831
GO:0019915 lipid storage P
IMP
CelWBGene00007555
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007555
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00007555
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000003831
GO:0048311 mitochondrion distribution P
IGI
SpoSPAC30C2.02

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC30C2.02
(Q9P6K9)		 YJR070C
(S000003831)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003831
SpoSPAC30C2.02
GO:0005737 cytoplasm C
IDA
SceS000003831
SpoSPAC30C2.02
GO:0005829 cytosol C
IDA
SpoSPAC30C2.02
GO:0019135 deoxyhypusine monooxygenase activity F
IDA
SceS000003831
IMP
SceS000003831
ISS
SpoSPAC30C2.02
GO:0000226 microtubule cytoskeleton organization P
IGI
SceS000003831
IMP
SceS000003831
GO:0007018 microtubule-based movement P
IMP
SpoSPAC30C2.02
GO:0008612 peptidyl-lysine modification to
hypusine		 P
IC
SpoSPAC30C2.02
IDA
SceS000003831
IMP
SceS000003831
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000003831
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000003831
GO:0048311 mitochondrion distribution P
IGI
SpoSPAC30C2.02

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GO info in one table:

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