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Search term: YJR073C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name OPI3
SGD link S000003834
Alternative ID YJR073C
Description Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis
Synonyms YJR073C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4142 ---HYP-

KOGs classification KOGs description
METABOLISM Phospholipid methyltransferase

Species KOG link NCBI link UniProt link
Homo sapiens (Hsa) Hs6005828 GI:6005828
Saccharomyces cerevisiae (Sce) YJR073c
(S000003834)		 GI:6322533 P05375
Schizosaccharomyces pombe (Spo) SPBC337.16 GI:19112209 O74827


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000003834
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC337.16
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPBC337.16
GO:0005792 microsome C
IDA
SceS000003834
GO:0016021 integral to membrane C
ISM
SceS000003834
GO:0000773 phosphatidyl-N-methylethanolamine
N-methyltransferase activity		 F
IDA
SceS000003834
IGI
SceS000003834
IMP
SceS000003834
ISS
SpoSPBC337.16
GO:0080101 phosphatidyl-N-dimethylethanolamine
N-methyltransferase activity		 F
IDA
SceS000003834
IGI
SceS000003834
IMP
SceS000003834
GO:0006656 phosphatidylcholine biosynthetic
process		 P
IDA
SceS000003834
IGI
SceS000003834
SpoSPBC337.16
IMP
SceS000003834
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000003834
GO:0007047 cellular cell wall organization P
RCA
SceS000003834
GO:0032259 methylation P
ISS
SpoSPBC337.16
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000003834

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6291

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PEMT GI:22538478
Pan troglodytes (Ptr) PEMT GI:114668891
Canis familiaris (Cfa) PEMT GI:73956258
Mus musculus (Mmu) Pemt
(MGI:104535)		 GI:33667036 Q3UZN8
Gallus gallus (Gga) PEMT GI:57525073
Schizosaccharomyces pombe (Spo) cho1
(SPBC337.16)		 GI:19112209 O74827
Saccharomyces cerevisiae (Sce) OPI3
(S000003834)		 GI:6322533 P05375
Kluyveromyces lactis (Kla) KLLA0B14234g GI:50304429
Eremothecium gossypii (Ego) AGOS_AFR431C GI:45198949
Magnaporthe grisea (Mgr) MGG_01295 GI:145613874
Neurospora crassa (Ncr) NCU04699.1 GI:32406886


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
ISO
MmuMGI:104535
GO:0005739 mitochondrion C
IDA
MmuMGI:104535
SceS000003834
GO:0005740 mitochondrial envelope C
TAS
MmuMGI:104535
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC337.16
GO:0005789 endoplasmic reticulum membrane C
IDA
MmuMGI:104535
ISS
SpoSPBC337.16
GO:0005792 microsome C
IDA
SceS000003834
GO:0016021 integral to membrane C
ISM
SceS000003834
GO:0031526 brush border membrane C
ISO
MmuMGI:104535
GO:0042383 sarcolemma C
ISO
MmuMGI:104535
GO:0000773 phosphatidyl-N-methylethanolamine
N-methyltransferase activity		 F
IDA
SceS000003834
IGI
SceS000003834
IMP
SceS000003834
ISS
SpoSPBC337.16
GO:0004608 phosphatidylethanolamine N-methyltransferase
activity		 F
ISO
MmuMGI:104535
ISS
MmuMGI:104535
GO:0008429 phosphatidylethanolamine binding F
ISO
MmuMGI:104535
GO:0008757 S-adenosylmethionine-dependent methyltransferase
activity		 F
ISO
MmuMGI:104535
GO:0080101 phosphatidyl-N-dimethylethanolamine
N-methyltransferase activity		 F
IDA
SceS000003834
IGI
SceS000003834
IMP
SceS000003834
GO:0006629 lipid metabolic process P
TAS
HsaPEMT
GO:0006650 glycerophospholipid metabolic process P
ISO
MmuMGI:104535
GO:0006656 phosphatidylcholine biosynthetic
process		 P
IDA
SceS000003834
IGI
SceS000003834
SpoSPBC337.16
IMP
SceS000003834
ISO
MmuMGI:104535
ISS
MmuMGI:104535
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000003834
GO:0007047 cellular cell wall organization P
RCA
SceS000003834
GO:0008283 cell proliferation P
TAS
HsaPEMT
GO:0008285 negative regulation of cell proliferation P
ISO
MmuMGI:104535
GO:0032259 methylation P
ISS
MmuMGI:104535
SpoSPBC337.16
GO:0033273 response to vitamin P
ISO
MmuMGI:104535
GO:0042493 response to drug P
ISO
MmuMGI:104535
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000003834
GO:0046498 S-adenosylhomocysteine metabolic
process		 P
ISO
MmuMGI:104535
GO:0046500 S-adenosylmethionine metabolic
process		 P
ISO
MmuMGI:104535
GO:0050747 positive regulation of lipoprotein metabolic
process		 P
ISO
MmuMGI:104535

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4994

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3623 AFR431C
Candida glabrata (Cgl) cgl1248 CAGL0F00363g
Cryptococcus neoformans (Cne) cne452 163.m06396
Dictyostelium discoideum (Ddi) ddi5433 DDB0204815
Debaryomyces hansenii (Dha) dha5227 DEHA0F18799g
Takifugu rubripes (Fru) fru4282 SINFRUP00000159627
Gallus gallus (Gga) gga6487 ENSGALP00000007770
(PEMT)		 Q5ZJB1
Homo sapiens (Hsa) hsa13157 ENSP00000255389
(PEMT)		 Q9UBM1-2
Homo sapiens (Hsa) hsa13156 ENSP00000345099
(PEMT)		 Q9UBM1-1
Kluyveromyces lactis (Kla) kla1162 KLLA0B14234g
Mus musculus (Mmu) mmu3815 ENSMUSP00000000310
(MGI:104535)		 Q61907
Mus musculus (Mmu) mmu3816 ENSMUSP00000077192
(MGI:104535)
Neurospora crassa (Ncr) ncr4565 NCU04699.2
Rattus norvegicus (Rno) rno5164 ENSRNOP00000004488
(RGD:3297)
Saccharomyces cerevisiae (Sce) sce3568 YJR073C
(S000003834)
Schizosaccharomyces pombe (Spo) spo4066 SPBC337.16 O74827
Yarrowia lipolytica (Yli) yli4379 YALI0E12441g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
ISO
MmuMGI:104535
GO:0005739 mitochondrion C
IDA
MmuMGI:104535
SceS000003834
GO:0005740 mitochondrial envelope C
TAS
MmuMGI:104535
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC337.16
GO:0005789 endoplasmic reticulum membrane C
IDA
MmuMGI:104535
ISS
SpoSPBC337.16
GO:0005792 microsome C
IDA
SceS000003834
GO:0016021 integral to membrane C
ISM
SceS000003834
GO:0031526 brush border membrane C
ISO
MmuMGI:104535
GO:0042383 sarcolemma C
ISO
MmuMGI:104535
GO:0000773 phosphatidyl-N-methylethanolamine
N-methyltransferase activity		 F
IDA
SceS000003834
IGI
SceS000003834
IMP
SceS000003834
ISS
SpoSPBC337.16
GO:0004608 phosphatidylethanolamine N-methyltransferase
activity		 F
ISO
MmuMGI:104535
ISS
MmuMGI:104535
GO:0008429 phosphatidylethanolamine binding F
ISO
MmuMGI:104535
GO:0008757 S-adenosylmethionine-dependent methyltransferase
activity		 F
ISO
MmuMGI:104535
GO:0080101 phosphatidyl-N-dimethylethanolamine
N-methyltransferase activity		 F
IDA
SceS000003834
IGI
SceS000003834
IMP
SceS000003834
GO:0006650 glycerophospholipid metabolic process P
ISO
MmuMGI:104535
GO:0006656 phosphatidylcholine biosynthetic
process		 P
IDA
SceS000003834
IGI
SceS000003834
SpoSPBC337.16
IMP
SceS000003834
ISO
MmuMGI:104535
ISS
MmuMGI:104535
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000003834
GO:0007047 cellular cell wall organization P
RCA
SceS000003834
GO:0008285 negative regulation of cell proliferation P
ISO
MmuMGI:104535
GO:0032259 methylation P
ISS
MmuMGI:104535
SpoSPBC337.16
GO:0033273 response to vitamin P
ISO
MmuMGI:104535
GO:0042493 response to drug P
ISO
MmuMGI:104535
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000003834
GO:0046498 S-adenosylhomocysteine metabolic
process		 P
ISO
MmuMGI:104535
GO:0046500 S-adenosylmethionine metabolic
process		 P
ISO
MmuMGI:104535
GO:0050747 positive regulation of lipoprotein metabolic
process		 P
ISO
MmuMGI:104535

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC337.16
(O74827)		 YJR073C
(S000003834)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000003834
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC337.16
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPBC337.16
GO:0005792 microsome C
IDA
SceS000003834
GO:0016021 integral to membrane C
ISM
SceS000003834
GO:0000773 phosphatidyl-N-methylethanolamine
N-methyltransferase activity		 F
IDA
SceS000003834
IGI
SceS000003834
IMP
SceS000003834
ISS
SpoSPBC337.16
GO:0080101 phosphatidyl-N-dimethylethanolamine
N-methyltransferase activity		 F
IDA
SceS000003834
IGI
SceS000003834
IMP
SceS000003834
GO:0006656 phosphatidylcholine biosynthetic
process		 P
IDA
SceS000003834
IGI
SceS000003834
SpoSPBC337.16
IMP
SceS000003834
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000003834
GO:0007047 cellular cell wall organization P
RCA
SceS000003834
GO:0032259 methylation P
ISS
SpoSPBC337.16
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000003834

Back to the top
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Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk