Search term: YJR078W

Gene summary:

HomoloGene results:

HomoloGene cluster	Phylogenetic pattern
48830

Species	Gene ID	NCBI link	UniProt link
Homo sapiens (Hsa)	IDO2	GI:148539554
Pan troglodytes (Ptr)	IDO2	GI:114619873
Canis familiaris (Cfa)	IDO2	GI:73979259
Mus musculus (Mmu)	Ido2 (MGI:2142489)	GI:22122379	A4UHF3
Rattus norvegicus (Rno)	Ido2	GI:109503528
Gallus gallus (Gga)	INDOL1	GI:118101384
Saccharomyces cerevisiae (Sce)	BNA2 (S000003839)	GI:6322538
Eremothecium gossypii (Ego)	AGOS_ACR188C	GI:45185874
Magnaporthe grisea (Mgr)	MGG_13773	GI:145602911
Neurospora crassa (Ncr)	NCU05752.1	GI:32410253

GO terms for Homologene results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005737	cytoplasm	C	IDA Mmu MGI:2142489 Sce S000003839 ISS Hsa IDO2
GO:0004833	tryptophan 2,3-dioxygenase activity	F	NAS Sce S000003839
GO:0033754	indoleamine 2,3-dioxygenase activity	F	IDA Hsa IDO2 Mmu MGI:2142489 IMP Mmu MGI:2142489 ISS Hsa IDO2 NAS Sce S000003839
GO:0019441	tryptophan catabolic process to kynurenine	P	IDA Hsa IDO2 Mmu MGI:2142489 IMP Mmu MGI:2142489 ISS Hsa IDO2
GO:0034354	de novo NAD biosynthetic process from tryptophan	P	IGI Sce S000003839

OrthoMCL results:

OrthoMCL cluster	Phylogenetic pattern
OG1_6821

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Ashbya gossypii (Ago)	ago1235	ACR188C
Cryptococcus neoformans (Cne)	cne5557	179.m00416
Debaryomyces hansenii (Dha)	dha6276	DEHA0G12947g
Takifugu rubripes (Fru)	fru23431	SINFRUP00000143857
Takifugu rubripes (Fru)	fru23432	SINFRUP00000143858
Gallus gallus (Gga)	gga23964	ENSGALP00000005476
Gallus gallus (Gga)	gga23965	ENSGALP00000005477
Homo sapiens (Hsa)	hsa30213	ENSP00000253513 (IDO1)	P14902
Mus musculus (Mmu)	mmu25760	ENSMUSP00000033953 (MGI:2142489)	Q8R0V5
Mus musculus (Mmu)	mmu25761	ENSMUSP00000033956 (MGI:96416)	P28776
Neurospora crassa (Ncr)	ncr5590	NCU05752.2
Rattus norvegicus (Rno)	rno12656	ENSRNOP00000036799 (GI:684861)
Rattus norvegicus (Rno)	rno12655	ENSRNOP00000050320 (RGD:619989)	Q9ERD9
Saccharomyces cerevisiae (Sce)	sce3573	YJR078W (S000003839)
Yarrowia lipolytica (Yli)	yli6449	YALI0F26455g

GO terms for OrthoMCL results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0005625	soluble fraction	C	ISO Mmu MGI:96416
GO:0005737	cytoplasm	C	IDA Mmu MGI:2142489 MGI:96416 Sce S000003839
GO:0005829	cytosol	C	ISO Mmu MGI:96416
GO:0004833	tryptophan 2,3-dioxygenase activity	F	IDA Mmu MGI:96416 NAS Sce S000003839
GO:0016597	amino acid binding	F	ISO Mmu MGI:96416
GO:0019825	oxygen binding	F	ISO Mmu MGI:96416
GO:0033754	indoleamine 2,3-dioxygenase activity	F	IDA Mmu MGI:2142489 IMP Mmu MGI:2142489 ISO Mmu MGI:96416 NAS Sce S000003839
GO:0002534	cytokine production involved in inflammatory response	P	IMP Mmu MGI:96416
GO:0002666	positive regulation of T cell tolerance induction	P	IMP Mmu MGI:96416
GO:0002678	positive regulation of chronic inflammatory response	P	IMP Mmu MGI:96416
GO:0002830	positive regulation of T-helper 2 type immune response	P	IMP Mmu MGI:96416
GO:0006952	defense response	P	TAS Mmu MGI:96416
GO:0006954	inflammatory response	P	IMP Mmu MGI:96416
GO:0007610	behavior	P	IMP Mmu MGI:96416
GO:0019441	tryptophan catabolic process to kynurenine	P	IDA Mmu MGI:2142489 MGI:96416 IMP Mmu MGI:2142489 ISO Mmu MGI:96416
GO:0032496	response to lipopolysaccharide	P	IMP Mmu MGI:96416
GO:0032693	negative regulation of interleukin-10 production	P	IMP Mmu MGI:96416
GO:0032735	positive regulation of interleukin-12 production	P	IMP Mmu MGI:96416
GO:0033555	multicellular organismal response to stress	P	IMP Mmu MGI:96416
GO:0034276	kynurenic acid biosynthetic process	P	IMP Mmu MGI:96416
GO:0034354	de novo NAD biosynthetic process from tryptophan	P	IGI Sce S000003839
GO:0042130	negative regulation of T cell proliferation	P	IMP Mmu MGI:96416
GO:0043065	positive regulation of apoptosis	P	IMP Mmu MGI:96416
GO:0046007	negative regulation of activated T cell proliferation	P	IMP Mmu MGI:96416
GO:0070233	negative regulation of T cell apoptosis	P	IMP Mmu MGI:96416