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Search term: YJR088C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name EMC2
SGD link S000003848
Alternative ID YJR088C
Description Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response
Synonyms YJR088C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3060 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g04830 GI:18397023
Arabidopsis thaliana (Ath) At5g28220 GI:15241730
Caenorhabditis elegans (Cel) CE19639
(WBGene00021973)		 GI:17537681 O76630
Drosophila melanogaster (Dme) 7300205 GI:7300205
Homo sapiens (Hsa) Hs7661910
(TTC35)		 GI:7661910 Q15006
Saccharomyces cerevisiae (Sce) YJR088c
(S000003848)		 GI:6322547 P47133
Schizosaccharomyces pombe (Spo) SPBC14C8.18c GI:19112713


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g28220
At3g04830
GO:0005783 endoplasmic reticulum C
IDA
HsaTTC35
SceS000003848
GO:0003674 molecular_function F
ND
SceS000003848
GO:0000003 reproduction P
IMP
CelWBGene00021973
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00021973
GO:0008150 biological_process P
ND
AthAt3g04830
At5g28220
GO:0034975 protein folding in endoplasmic
reticulum		 P
IGI
SceS000003848
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00021973
GO:0040011 locomotion P
IMP
CelWBGene00021973
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00021973

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39467

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) YJR088C
(S000003848)		 GI:6322547 P47133
Kluyveromyces lactis (Kla) KLLA0E06072g GI:50308441
Eremothecium gossypii (Ego) AGOS_ACR173W GI:45185859


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000003848
GO:0003674 molecular_function F
ND
SceS000003848
GO:0034975 protein folding in endoplasmic
reticulum		 P
IGI
SceS000003848

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2326

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3207 ENSANGP00000012014
Ashbya gossypii (Ago) ago1220 ACR173W
Arabidopsis thaliana (Ath) ath12528 At3g04830.1
Arabidopsis thaliana (Ath) ath12529 At3g04830.2
Arabidopsis thaliana (Ath) ath25098 At5g28220.1
Caenorhabditis elegans (Cel) cel20082 Y57G7A.10a
(CE19639;
WBGene00021973)
Caenorhabditis elegans (Cel) cel20083 Y57G7A.10b
Candida glabrata (Cgl) cgl5055 CAGL0M09185g
Cryptococcus neoformans (Cne) cne2329 181.m08353
Dictyostelium discoideum (Ddi) ddi3346 DDB0169127
Debaryomyces hansenii (Dha) dha6855 DEHA0G26015g
Drosophila melanogaster (Dme) dme13005 CG17556-PA
(FBgn0038462)
Drosophila melanogaster (Dme) dme13002 CG3678-PA
(FBgn0038461)
Danio rerio (Dre) dre1037 ENSDARP00000006378
(ttc35)		 Q6TGY8
Takifugu rubripes (Fru) fru24223 SINFRUP00000146667
Gallus gallus (Gga) gga11443 ENSGALP00000025890
(TTC35)
Homo sapiens (Hsa) hsa30637 ENSP00000220853
(TTC35)		 Q15006
Kluyveromyces lactis (Kla) kla3221 KLLA0E06072g
Mus musculus (Mmu) mmu8938 ENSMUSP00000022962
(MGI:1913986)		 Q9CRD2
Neurospora crassa (Ncr) ncr4519 NCU04651.2
Plasmodium falciparum (Pfa) pfa1390 PF14_0098
Rattus norvegicus (Rno) rno27026 ENSRNOP00000006890
(RGD:1310430)		 B0BNG0
Saccharomyces cerevisiae (Sce) sce3582 YJR088C
(S000003848)
Schizosaccharomyces pombe (Spo) spo498 SPBC15C4.01c O60110
Yarrowia lipolytica (Yli) yli2649 YALI0C23188g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g28220
At3g04830
GO:0005634 nucleus C
IDA
SpoSPBC15C4.01c
GO:0005739 mitochondrion C
IDA
MmuMGI:1913986
GO:0005783 endoplasmic reticulum C
IDA
SceS000003848
ISS
SpoSPBC15C4.01c
GO:0005816 spindle pole body C
IDA
SpoSPBC15C4.01c
GO:0005829 cytosol C
IDA
SpoSPBC15C4.01c
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0038462
FBgn0038461
GO:0032153 cell division site C
IDA
SpoSPBC15C4.01c
GO:0043234 protein complex C
NAS
SpoSPBC15C4.01c
GO:0003674 molecular_function F
ND
MmuMGI:1913986
SceS000003848
SpoSPBC15C4.01c
GO:0000003 reproduction P
IMP
CelWBGene00021973
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00021973
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC15C4.01c
GO:0008150 biological_process P
ND
AthAt3g04830
At5g28220
MmuMGI:1913986
GO:0034975 protein folding in endoplasmic
reticulum		 P
IGI
SceS000003848
ISS
SpoSPBC15C4.01c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00021973
GO:0040011 locomotion P
IMP
CelWBGene00021973
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00021973

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC15C4.01c
(O60110)		 YJR088C
(S000003848)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC15C4.01c
GO:0005783 endoplasmic reticulum C
IDA
SceS000003848
ISS
SpoSPBC15C4.01c
GO:0005816 spindle pole body C
IDA
SpoSPBC15C4.01c
GO:0005829 cytosol C
IDA
SpoSPBC15C4.01c
GO:0032153 cell division site C
IDA
SpoSPBC15C4.01c
GO:0043234 protein complex C
NAS
SpoSPBC15C4.01c
GO:0003674 molecular_function F
ND
SceS000003848
SpoSPBC15C4.01c
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC15C4.01c
GO:0034975 protein folding in endoplasmic
reticulum		 P
IGI
SceS000003848
ISS
SpoSPBC15C4.01c

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