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Search term: YJR139C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HOM6
SGD link S000003900
Alternative ID YJR139C
Description Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions
Synonyms YJR139C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0455 A---YP-

KOGs classification KOGs description
METABOLISM Homoserine dehydrogenase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g21060 GI:15242147
Saccharomyces cerevisiae (Sce) YJR139c
(S000003900)
GI:6322599 P31116
Schizosaccharomyces pombe (Spo) SPBC776.03 GI:19113110 O94671
Arabidopsis thaliana (Ath) At5g21060 GI:15242147
Saccharomyces cerevisiae (Sce) YJR139c
(S000003900)
GI:6322599 P31116
Schizosaccharomyces pombe (Spo) SPBC776.03 GI:19113110 O94671
Arabidopsis thaliana (Ath) At5g21060 GI:15242147
Saccharomyces cerevisiae (Sce) YJR139c
(S000003900)
GI:6322599 P31116
Schizosaccharomyces pombe (Spo) SPBC776.03 GI:19113110 O94671


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g21060
SpoSPBC776.03
GO:0005634 nucleus C
IDA
SceS000003900
GO:0005737 cytoplasm C
IDA
SceS000003900
GO:0004412 homoserine dehydrogenase activity F
IDA
SceS000003900
ISS
AthAt5g21060
SceS000003900
SpoSPBC776.03
GO:0006555 methionine metabolic process P
TAS
SceS000003900
GO:0006566 threonine metabolic process P
TAS
SceS000003900
GO:0008652 cellular amino acid biosynthetic
process
P
ISS
AthAt5g21060
GO:0009067 aspartate family amino acid biosynthetic
process
P
ISS
AthAt5g21060
GO:0009086 methionine biosynthetic process P
ISS
SpoSPBC776.03
GO:0009088 threonine biosynthetic process P
ISS
SpoSPBC776.03
GO:0009090 homoserine biosynthetic process P
ISS
SpoSPBC776.03
TAS
SceS000003900

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6312

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPBC776.03 GI:19113110 O94671
Saccharomyces cerevisiae (Sce) HOM6
(S000003900)
GI:6322599 P31116
Kluyveromyces lactis (Kla) KLLA0B03872g GI:50303529
Eremothecium gossypii (Ego) AGOS_ABL080W GI:45185150
Magnaporthe grisea (Mgr) MGG_11450 GI:145610643
Neurospora crassa (Ncr) NCU03935.1 GI:32405282
Arabidopsis thaliana (Ath) AK-HSDH_I GI:15221653
Oryza sativa (Osa) Os08g0342400 GI:115475992
Oryza sativa (Osa) Os09g0294000 GI:115478398


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SpoSPBC776.03
GO:0005634 nucleus C
IDA
SceS000003900
GO:0005737 cytoplasm C
IDA
SceS000003900
GO:0004412 homoserine dehydrogenase activity F
IDA
SceS000003900
ISS
SceS000003900
SpoSPBC776.03
GO:0006555 methionine metabolic process P
TAS
SceS000003900
GO:0006566 threonine metabolic process P
TAS
SceS000003900
GO:0009086 methionine biosynthetic process P
ISS
SpoSPBC776.03
GO:0009088 threonine biosynthetic process P
ISS
SpoSPBC776.03
GO:0009090 homoserine biosynthetic process P
ISS
SpoSPBC776.03
TAS
SceS000003900

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_5111

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga12765 ENSANGP00000002199
Ashbya gossypii (Ago) ago512 ABL080W
Arabidopsis thaliana (Ath) ath3263 At1g31230.1
Arabidopsis thaliana (Ath) ath19870 At4g19710.1
Arabidopsis thaliana (Ath) ath19871 At4g19710.2
Candida glabrata (Cgl) cgl4669 CAGL0M00330g
Cryptococcus neoformans (Cne) cne3956 185.m02548
Debaryomyces hansenii (Dha) dha4452 DEHA0F01507g
Escherichia coli (Eco) eco2 16127996
Escherichia coli (Eco) eco3797 16131778
Kluyveromyces lactis (Kla) kla704 KLLA0B03872g
Neurospora crassa (Ncr) ncr3824 NCU03935.2
Oryza sativa (Osa) osa16175 3127.m00133
Oryza sativa (Osa) osa78035 7334.m00148
Oryza sativa (Osa) osa78040 7334.m00178
Saccharomyces cerevisiae (Sce) sce3636 YJR139C
(S000003900)
Schizosaccharomyces pombe (Spo) spo59 SPBC776.03 O94671
Yarrowia lipolytica (Yli) yli2752 YALI0D01089g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SpoSPBC776.03
GO:0005634 nucleus C
IDA
SceS000003900
GO:0005737 cytoplasm C
IDA
SceS000003900
GO:0009507 chloroplast C
IDA
AthAt1g31230
At4g19710
GO:0009570 chloroplast stroma C
IDA
AthAt1g31230
GO:0004072 aspartate kinase activity F
IDA
AthAt4g19710
At1g31230
GO:0004412 homoserine dehydrogenase activity F
IDA
AthAt4g19710
At1g31230
SceS000003900
ISS
SceS000003900
SpoSPBC776.03
GO:0006555 methionine metabolic process P
TAS
SceS000003900
GO:0006566 threonine metabolic process P
TAS
SceS000003900
GO:0009067 aspartate family amino acid biosynthetic
process
P
TAS
AthAt1g31230
At4g19710
GO:0009086 methionine biosynthetic process P
ISS
SpoSPBC776.03
GO:0009088 threonine biosynthetic process P
ISS
SpoSPBC776.03
GO:0009090 homoserine biosynthetic process P
ISS
SpoSPBC776.03
TAS
SceS000003900

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC776.03
(O94671)
YJR139C
(S000003900)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SpoSPBC776.03
GO:0005634 nucleus C
IDA
SceS000003900
GO:0005737 cytoplasm C
IDA
SceS000003900
GO:0004412 homoserine dehydrogenase activity F
IDA
SceS000003900
ISS
SceS000003900
SpoSPBC776.03
GO:0006555 methionine metabolic process P
TAS
SceS000003900
GO:0006566 threonine metabolic process P
TAS
SceS000003900
GO:0009086 methionine biosynthetic process P
ISS
SpoSPBC776.03
GO:0009088 threonine biosynthetic process P
ISS
SpoSPBC776.03
GO:0009090 homoserine biosynthetic process P
ISS
SpoSPBC776.03
TAS
SceS000003900

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