YOGY Home YOGY Help

Search term: YKL002W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DID4
SGD link S000001485
Alternative ID YKL002W
Description Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis
Synonyms YKL002W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3230 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Vacuolar assembly/sorting protein DID4

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g03950 GI:4204294
Arabidopsis thaliana (Ath) At2g06530 GI:15225131
Arabidopsis thaliana (Ath) At5g44560 GI:15241525
Caenorhabditis elegans (Cel) CE21987
(WBGene00012903)
GI:17537141 Q9U2F6
Drosophila melanogaster (Dme) 7301433 GI:7301433
Homo sapiens (Hsa) Hs7656922
(CHMP2A)
GI:7656922 O43633
Saccharomyces cerevisiae (Sce) YKL002w
(S000001485)
GI:9755336 P36108
Schizosaccharomyces pombe (Spo) SPAC4F8.01 GI:19114783 O14177


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000815 ESCRT III complex C
IDA
SceS000001485
ISS
AthAt5g44560
At1g03950
At2g06530
SpoSPAC4F8.01
GO:0005737 cytoplasm C
IDA
SceS000001485
SpoSPAC4F8.01
GO:0003674 molecular_function F
ND
SceS000001485
SpoSPAC4F8.01
GO:0019904 protein domain specific binding F
IPI
HsaCHMP2A
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00012903
GO:0016192 vesicle-mediated transport P
ISS
AthAt2g06530
At5g44560
At1g03950
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway
P
IC
SceS000001485
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway
P
IMP
SpoSPAC4F8.01
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000001485
ISS
SpoSPAC4F8.01
GO:0045184 establishment of protein localization P
RCA
SceS000001485
GO:0045324 late endosome to vacuole transport P
IMP
SpoSPAC4F8.01
IPI
SceS000001485
GO:0070676 intralumenal vesicle formation P
IMP
SceS000001485

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6382

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CHMP2A GI:7656922 O43633
Pan troglodytes (Ptr) CHMP2A GI:114679467
Canis familiaris (Cfa) CHMP2A GI:57036131
Mus musculus (Mmu) Chmp2a
(MGI:1916203)
GI:21312151 Q9DB34
Rattus norvegicus (Rno) Chmp2a GI:109458047
Gallus gallus (Gga) CHMP2A GI:118105778
Drosophila melanogaster (Dme) CG14542
(FBgn0039402)
GI:24650245
Anopheles gambiae (Aga) AgaP_AGAP001285 GI:158302285
Caenorhabditis elegans (Cel) Y46G5A.12
(CE21987;
WBGene00012903)
GI:17537141 Q9U2F6
Schizosaccharomyces pombe (Spo) did4
(SPAC4F8.01)
GI:63054573 O14177
Saccharomyces cerevisiae (Sce) DID4
(S000001485)
GI:9755336 P36108
Kluyveromyces lactis (Kla) KLLA0B13343g GI:50304351
Eremothecium gossypii (Ego) AGOS_ABR002C GI:45185231
Magnaporthe grisea (Mgr) MGG_05208 GI:39940064
Neurospora crassa (Ncr) NCU00435.1 GI:32403816
Arabidopsis thaliana (Ath) VPS2.1 GI:18396352
Oryza sativa (Osa) Os07g0236800 GI:115471299
Plasmodium falciparum (Pfa) PF08_0064 GI:124512458


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000815 ESCRT III complex C
IDA
SceS000001485
ISS
AthVPS2.1
SpoSPAC4F8.01
GO:0005737 cytoplasm C
IDA
SceS000001485
SpoSPAC4F8.01
GO:0005829 cytosol C
IDA
MmuMGI:1916203
GO:0003674 molecular_function F
ND
SceS000001485
SpoSPAC4F8.01
GO:0005515 protein binding F
IPI
MmuMGI:1916203
GO:0019904 protein domain specific binding F
IPI
HsaCHMP2A
GO:0008150 biological_process P
ND
MmuMGI:1916203
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00012903
GO:0016192 vesicle-mediated transport P
ISS
AthVPS2.1
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway
P
IC
SceS000001485
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway
P
IMP
SpoSPAC4F8.01
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000001485
ISS
SpoSPAC4F8.01
GO:0045184 establishment of protein localization P
RCA
SceS000001485
GO:0045324 late endosome to vacuole transport P
IMP
SpoSPAC4F8.01
IPI
SceS000001485
GO:0070676 intralumenal vesicle formation P
IMP
SceS000001485

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2544

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga3362 ENSANGP00000020919
Ashbya gossypii (Ago) ago593 ABR002C
Arabidopsis thaliana (Ath) ath8010 At2g06530.1
Caenorhabditis elegans (Cel) cel18995 Y46G5A.12
(CE21987;
WBGene00012903)
Candida glabrata (Cgl) cgl3643 CAGL0K02827g
Dictyostelium discoideum (Ddi) ddi10451 DDB0184359
Debaryomyces hansenii (Dha) dha3832 DEHA0E13376g
Drosophila melanogaster (Dme) dme14559 CG14542-PA
(FBgn0039402)
Danio rerio (Dre) dre3610 ENSDARP00000023807
Danio rerio (Dre) dre3588 ENSDARP00000041609
Takifugu rubripes (Fru) fru3563 SINFRUP00000140609
Homo sapiens (Hsa) hsa17312 ENSP00000310440
(CHMP2A)
O43633
Kluyveromyces lactis (Kla) kla1123 KLLA0B13343g
Mus musculus (Mmu) mmu30916 ENSMUSP00000005711
(MGI:1916203)
Q9DB34
Neurospora crassa (Ncr) ncr421 NCU00435.2
Oryza sativa (Osa) osa41720 5137.m00163
Oryza sativa (Osa) osa42101 5273.m00192
Oryza sativa (Osa) osa54961 6094.m00053
Oryza sativa (Osa) osa54969 6094.m00093
Plasmodium falciparum (Pfa) pfa2158 PF08_0064
Rattus norvegicus (Rno) rno1044 ENSRNOP00000038229
(RGD:1305050)
B2RZB5
Saccharomyces cerevisiae (Sce) sce3663 YKL002W
(S000001485)
Schizosaccharomyces pombe (Spo) spo1336 SPAC4F8.01 O14177
Yarrowia lipolytica (Yli) yli3872 YALI0E00396g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000815 ESCRT III complex C
IDA
SceS000001485
ISS
AthAt2g06530
SpoSPAC4F8.01
GO:0005737 cytoplasm C
IDA
SceS000001485
SpoSPAC4F8.01
GO:0005829 cytosol C
IDA
MmuMGI:1916203
GO:0003674 molecular_function F
ND
SceS000001485
SpoSPAC4F8.01
GO:0005515 protein binding F
IPI
MmuMGI:1916203
GO:0008150 biological_process P
ND
MmuMGI:1916203
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00012903
GO:0016192 vesicle-mediated transport P
ISS
AthAt2g06530
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway
P
IC
SceS000001485
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway
P
IMP
SpoSPAC4F8.01
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000001485
ISS
SpoSPAC4F8.01
GO:0045184 establishment of protein localization P
RCA
SceS000001485
GO:0045324 late endosome to vacuole transport P
IMP
SpoSPAC4F8.01
IPI
SceS000001485
GO:0070676 intralumenal vesicle formation P
IMP
SceS000001485

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC4F8.01
(O14177)
YKL002W
(S000001485)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000815 ESCRT III complex C
IDA
SceS000001485
ISS
SpoSPAC4F8.01
GO:0005737 cytoplasm C
IDA
SceS000001485
SpoSPAC4F8.01
GO:0003674 molecular_function F
ND
SceS000001485
SpoSPAC4F8.01
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway
P
IC
SceS000001485
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway
P
IMP
SpoSPAC4F8.01
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000001485
ISS
SpoSPAC4F8.01
GO:0045184 establishment of protein localization P
RCA
SceS000001485
GO:0045324 late endosome to vacuole transport P
IMP
SpoSPAC4F8.01
IPI
SceS000001485
GO:0070676 intralumenal vesicle formation P
IMP
SceS000001485

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk