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Search term: YKL007W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CAP1
SGD link S000001490
Alternative ID YKL007W
Description Alpha subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches
Synonyms YKL007W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0836 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING F-actin capping protein, alpha subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g05520 GI:15230004
Caenorhabditis elegans (Cel) CE04295
(WBGene00000292)		 GI:17539460 P34685
Drosophila melanogaster (Dme) 7291228
(cpa)		 GI:19922662
Homo sapiens (Hsa) Hs15277417
(CAPZA3)		 GI:15277417 Q96KX2
Homo sapiens (Hsa) Hs17459523 GI:17459523
Homo sapiens (Hsa) Hs22049951 GI:22049951
Homo sapiens (Hsa) Hs22057708 GI:22057708
Homo sapiens (Hsa) Hs5453597
(CAPZA1)		 GI:5453597 P52907
Homo sapiens (Hsa) Hs5453599
(CAPZA2)		 GI:5453599 P47755
Saccharomyces cerevisiae (Sce) YKL007w
(S000001490)		 GI:6322845 P28495
Schizosaccharomyces pombe (Spo) SPAC12B10.07 GI:19115551 Q10434
Arabidopsis thaliana (Ath) At3g05520 GI:15230004
Caenorhabditis elegans (Cel) CE04295
(WBGene00000292)		 GI:17539460 P34685
Drosophila melanogaster (Dme) 7291228
(cpa)		 GI:19922662
Homo sapiens (Hsa) Hs15277417
(CAPZA3)		 GI:15277417 Q96KX2
Homo sapiens (Hsa) Hs17459523 GI:17459523
Homo sapiens (Hsa) Hs22049951 GI:22049951
Homo sapiens (Hsa) Hs22057708 GI:22057708
Homo sapiens (Hsa) Hs5453597
(CAPZA1)		 GI:5453597 P52907
Homo sapiens (Hsa) Hs5453599
(CAPZA2)		 GI:5453599 P47755
Saccharomyces cerevisiae (Sce) YKL007w
(S000001490)		 GI:6322845 P28495
Schizosaccharomyces pombe (Spo) SPAC12B10.07 GI:19115551 Q10434


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
AthAt3g05520
GO:0005856 cytoskeleton C
TAS
HsaCAPZA1
GO:0005869 dynactin complex C
ISS
Dmecpa
GO:0005875 microtubule associated complex C
IDA
Dmecpa
GO:0005884 actin filament C
IDA
SpoSPAC12B10.07
IPI
SceS000001490
GO:0008290 F-actin capping protein complex C
IDA
SceS000001490
SpoSPAC12B10.07
IGI
SceS000001490
IMP
SceS000001490
IPI
SceS000001490
ISS
AthAt3g05520
SceS000001490
NAS
Dmecpa
GO:0015629 actin cytoskeleton C
TAS
HsaCAPZA2
CAPZA1
GO:0016324 apical plasma membrane C
IDA
Dmecpa
GO:0030479 actin cortical patch C
IDA
SceS000001490
SpoSPAC12B10.07
GO:0032153 cell division site C
IDA
SpoSPAC12B10.07
GO:0043332 mating projection tip C
IDA
SceS000001490
GO:0051286 cell tip C
IDA
SpoSPAC12B10.07
GO:0071203 WASH complex C
IDA
HsaCAPZA1
GO:0003779 actin binding F
ISS
AthAt3g05520
GO:0005515 protein binding F
IPI
HsaCAPZA2
CAPZA1
GO:0051015 actin filament binding F
IDA
SpoSPAC12B10.07
IGI
SceS000001490
IMP
SceS000001490
IPI
SceS000001490
ISS
SceS000001490
GO:0000003 reproduction P
IMP
CelWBGene00000292
GO:0002119 nematode larval development P
IMP
CelWBGene00000292
GO:0006461 protein complex assembly P
TAS
HsaCAPZA2
CAPZA1
GO:0006911 phagocytosis, engulfment P
IMP
Dmecpa
GO:0006928 cellular component movement P
TAS
HsaCAPZA1
CAPZA2
GO:0006970 response to osmotic stress P
RCA
SceS000001490
GO:0007015 actin filament organization P
IMP
Dmecpa
GO:0007018 microtubule-based movement P
ISS
Dmecpa
GO:0007294 germarium-derived oocyte fate determination P
IMP
Dmecpa
GO:0008360 regulation of cell shape P
IGI
SpoSPAC12B10.07
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000292
GO:0010591 regulation of lamellipodium assembly P
IMP
Dmecpa
GO:0030036 actin cytoskeleton organization P
IGI
SpoSPAC12B10.07
IMP
Dmecpa
ISS
AthAt3g05520
NAS
Dmecpa
GO:0030835 negative regulation of actin filament
depolymerization		 P
IDA
SpoSPAC12B10.07
GO:0030837 negative regulation of actin filament
polymerization		 P
IMP
Dmecpa
GO:0033205 cell cycle cytokinesis P
IGI
SpoSPAC12B10.07
GO:0034613 cellular protein localization P
IGI
SpoSPAC12B10.07
GO:0035220 wing disc development P
IMP
Dmecpa
GO:0040007 growth P
IMP
CelWBGene00000292
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000292
GO:0051016 barbed-end actin filament capping P
IDA
SceS000001490
SpoSPAC12B10.07
ISS
Dmecpa
NAS
Dmecpa
GO:0051049 regulation of transport P
RCA
SceS000001490

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
55956

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CAPZA2 GI:5453599 P47755
Pan troglodytes (Ptr) CAPZA2 GI:114615615
Canis familiaris (Cfa) CAPZA2 GI:61316477
Mus musculus (Mmu) Capza2
(MGI:106222)		 GI:6671672 P47754
Rattus norvegicus (Rno) Capza2
(RGD:1549770)		 GI:57163991
Gallus gallus (Gga) CAPZA2 GI:52138663
Saccharomyces cerevisiae (Sce) CAP1
(S000001490)		 GI:6322845 P28495
Kluyveromyces lactis (Kla) CAPA_KLULA GI:50304361
Eremothecium gossypii (Ego) AGOS_ABR007C GI:45185236
Magnaporthe grisea (Mgr) MGG_12818 GI:145608614
Neurospora crassa (Ncr) NCU03911.1 GI:32405234


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005884 actin filament C
IPI
SceS000001490
GO:0008290 F-actin capping protein complex C
IDA
SceS000001490
IGI
SceS000001490
IMP
SceS000001490
IPI
SceS000001490
ISS
SceS000001490
GO:0015629 actin cytoskeleton C
TAS
HsaCAPZA2
GO:0016020 membrane C
IDA
MmuMGI:106222
GO:0030479 actin cortical patch C
IDA
SceS000001490
GO:0030863 cortical cytoskeleton C
IDA
MmuMGI:106222
GO:0043332 mating projection tip C
IDA
SceS000001490
GO:0005515 protein binding F
IPI
HsaCAPZA2
GO:0051015 actin filament binding F
IGI
SceS000001490
IMP
SceS000001490
IPI
SceS000001490
ISS
SceS000001490
GO:0006461 protein complex assembly P
TAS
HsaCAPZA2
GO:0006928 cellular component movement P
TAS
HsaCAPZA2
GO:0006970 response to osmotic stress P
RCA
SceS000001490
GO:0051016 barbed-end actin filament capping P
IDA
SceS000001490
GO:0051049 regulation of transport P
RCA
SceS000001490

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2290

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1615 ENSANGP00000017140
Ashbya gossypii (Ago) ago598 ABR007C
Arabidopsis thaliana (Ath) ath12607 At3g05520.1
Caenorhabditis elegans (Cel) cel5080 D2024.6
(CE04295;
WBGene00000292)
Candida glabrata (Cgl) cgl3641 CAGL0K02783g
Cryptococcus neoformans (Cne) cne5132 186.m04080
Dictyostelium discoideum (Ddi) ddi12022 DDB0191243
Debaryomyces hansenii (Dha) dha4178 DEHA0E21153g
Drosophila melanogaster (Dme) dme6259 CG10540-PA
(FBgn0034577)
Danio rerio (Dre) dre22717 ENSDARP00000015539
Danio rerio (Dre) dre22728 ENSDARP00000041236
Takifugu rubripes (Fru) fru4922 SINFRUP00000134542
Takifugu rubripes (Fru) fru3913 SINFRUP00000144031
Gallus gallus (Gga) gga13510 ENSGALP00000002349
(CAPZA1)		 P13127
Gallus gallus (Gga) gga313 ENSGALP00000015277
(CAPZA2)		 P28497
Homo sapiens (Hsa) hsa1722 ENSP00000263168
(CAPZA1)		 P52907
Homo sapiens (Hsa) hsa29313 ENSP00000354947
(CAPZA2)		 P47755
Kluyveromyces lactis (Kla) kla1128 KLLA0B13453g
Mus musculus (Mmu) mmu21466 ENSMUSP00000015877
(MGI:106222)		 P47754
Mus musculus (Mmu) mmu17308 ENSMUSP00000051540
Mus musculus (Mmu) mmu860 ENSMUSP00000072398
Neurospora crassa (Ncr) ncr3800 NCU03911.2
Oryza sativa (Osa) osa53919 6051.m00161
Plasmodium falciparum (Pfa) pfa3732 PFE1420w
Rattus norvegicus (Rno) rno16773 ENSRNOP00000018713
(RGD:1587438)
Rattus norvegicus (Rno) rno20878 ENSRNOP00000037217
(RGD:1549770)		 Q3T1K5
Saccharomyces cerevisiae (Sce) sce3669 YKL007W
(S000001490)
Schizosaccharomyces pombe (Spo) spo3328 SPAC12B10.07 Q10434
Yarrowia lipolytica (Yli) yli4082 YALI0E05291g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
AthAt3g05520
GO:0005869 dynactin complex C
ISS
DmeFBgn0034577
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0034577
GO:0005884 actin filament C
IDA
SpoSPAC12B10.07
IPI
SceS000001490
GO:0008290 F-actin capping protein complex C
IDA
SceS000001490
SpoSPAC12B10.07
IGI
SceS000001490
IMP
SceS000001490
IPI
SceS000001490
ISS
AthAt3g05520
SceS000001490
NAS
DmeFBgn0034577
GO:0016020 membrane C
IDA
MmuMGI:106222
GO:0016324 apical plasma membrane C
IDA
DmeFBgn0034577
GO:0030479 actin cortical patch C
IDA
SceS000001490
SpoSPAC12B10.07
GO:0030863 cortical cytoskeleton C
IDA
MmuMGI:106222
GO:0032153 cell division site C
IDA
SpoSPAC12B10.07
GO:0043332 mating projection tip C
IDA
SceS000001490
GO:0051286 cell tip C
IDA
SpoSPAC12B10.07
GO:0003779 actin binding F
ISS
AthAt3g05520
GO:0051015 actin filament binding F
IDA
SpoSPAC12B10.07
IGI
SceS000001490
IMP
SceS000001490
IPI
SceS000001490
ISS
SceS000001490
GO:0000003 reproduction P
IMP
CelWBGene00000292
GO:0002119 nematode larval development P
IMP
CelWBGene00000292
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0034577
GO:0006970 response to osmotic stress P
RCA
SceS000001490
GO:0007015 actin filament organization P
IMP
DmeFBgn0034577
GO:0007018 microtubule-based movement P
ISS
DmeFBgn0034577
GO:0007294 germarium-derived oocyte fate determination P
IMP
DmeFBgn0034577
GO:0008360 regulation of cell shape P
IGI
SpoSPAC12B10.07
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000292
GO:0010591 regulation of lamellipodium assembly P
IMP
DmeFBgn0034577
GO:0030036 actin cytoskeleton organization P
IGI
SpoSPAC12B10.07
IMP
DmeFBgn0034577
ISS
AthAt3g05520
NAS
DmeFBgn0034577
GO:0030835 negative regulation of actin filament
depolymerization		 P
IDA
SpoSPAC12B10.07
GO:0030837 negative regulation of actin filament
polymerization		 P
IMP
DmeFBgn0034577
GO:0033205 cell cycle cytokinesis P
IGI
SpoSPAC12B10.07
GO:0034613 cellular protein localization P
IGI
SpoSPAC12B10.07
GO:0035220 wing disc development P
IMP
DmeFBgn0034577
GO:0040007 growth P
IMP
CelWBGene00000292
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000292
GO:0051016 barbed-end actin filament capping P
IDA
SceS000001490
SpoSPAC12B10.07
ISS
DmeFBgn0034577
NAS
DmeFBgn0034577
GO:0051049 regulation of transport P
RCA
SceS000001490

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC12B10.07
(Q10434)		 YKL007W
(S000001490)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005884 actin filament C
IDA
SpoSPAC12B10.07
IPI
SceS000001490
GO:0008290 F-actin capping protein complex C
IDA
SceS000001490
SpoSPAC12B10.07
IGI
SceS000001490
IMP
SceS000001490
IPI
SceS000001490
ISS
SceS000001490
GO:0030479 actin cortical patch C
IDA
SceS000001490
SpoSPAC12B10.07
GO:0032153 cell division site C
IDA
SpoSPAC12B10.07
GO:0043332 mating projection tip C
IDA
SceS000001490
GO:0051286 cell tip C
IDA
SpoSPAC12B10.07
GO:0051015 actin filament binding F
IDA
SpoSPAC12B10.07
IGI
SceS000001490
IMP
SceS000001490
IPI
SceS000001490
ISS
SceS000001490
GO:0006970 response to osmotic stress P
RCA
SceS000001490
GO:0008360 regulation of cell shape P
IGI
SpoSPAC12B10.07
GO:0030036 actin cytoskeleton organization P
IGI
SpoSPAC12B10.07
GO:0030835 negative regulation of actin filament
depolymerization		 P
IDA
SpoSPAC12B10.07
GO:0033205 cell cycle cytokinesis P
IGI
SpoSPAC12B10.07
GO:0034613 cellular protein localization P
IGI
SpoSPAC12B10.07
GO:0051016 barbed-end actin filament capping P
IDA
SceS000001490
SpoSPAC12B10.07
GO:0051049 regulation of transport P
RCA
SceS000001490

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