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Search term: YKL018W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SWD2
SGD link S000001501
Alternative ID YKL018W
Description Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lys 4 and is involved in telomeric silencing; subunit of CPF (cleavage and polyadenylation factor), a complex involved in RNAP II transcription termination
Synonyms YKL018W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1446 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSINGCELLULAR PROCESSES AND SIGNALING Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g14530 GI:15241434
Arabidopsis thaliana (Ath) At5g66240 GI:10177418
Caenorhabditis elegans (Cel) CE04149
(WBGene00016373)		 GI:17538992 Q18404
Caenorhabditis elegans (Cel) CE04150
(WBGene00016374)		 GI:17538994 Q18403
Drosophila melanogaster (Dme) 7295945 GI:20129177
Drosophila melanogaster (Dme) 7297395
(FBgn0032030)		 GI:19920938
Homo sapiens (Hsa) Hs17434629 GI:17434629
Saccharomyces cerevisiae (Sce) YKL018w
(S000001501)		 GI:6322834 P36104
Schizosaccharomyces pombe (Spo) SPAC824.04 GI:19114355 Q9UT39
Schizosaccharomyces pombe (Spo) SPBC18H10.06c GI:19112522 O60137
Encephalitozoon cuniculi (Ecu) ECU04g1580 GI:19074237 Q8SVQ1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPBC18H10.06c
GO:0005634 nucleus C
IDA
SpoSPAC824.04
GO:0005829 cytosol C
IDA
SpoSPAC824.04
SPBC18H10.06c
GO:0005847 mRNA cleavage and polyadenylation specificity
factor complex		 C
IDA
SpoSPAC824.04
IPI
SceS000001501
GO:0008352 katanin complex C
ISS
DmeFBgn0032030
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPBC18H10.06c
IPI
SceS000001501
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt5g14530
At5g66240
GO:0000166 nucleotide binding F
ISS
AthAt5g66240
At5g14530
GO:0003674 molecular_function F
ND
SpoSPAC824.04
SPBC18H10.06c
GO:0042800 histone methyltransferase activity (H3-K4
specific)		 F
IDA
SceS000001501
GO:0000003 reproduction P
IMP
CelWBGene00016374
GO:0000723 telomere maintenance P
IMP
SceS000001501
GO:0002119 nematode larval development P
IMP
CelWBGene00016374
GO:0006338 chromatin remodeling P
IC
SpoSPBC18H10.06c
GO:0006353 transcription termination P
RCA
SceS000001501
GO:0006378 mRNA polyadenylation P
IC
SpoSPAC824.04
GO:0006379 mRNA cleavage P
IC
SpoSPAC824.04
GO:0008150 biological_process P
ND
AthAt5g14530
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00016374
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016374
GO:0016074 snoRNA metabolic process P
RCA
SceS000001501
GO:0016571 histone methylation P
IMP
SpoSPBC18H10.06c
GO:0030846 termination of RNA polymerase II transcription,
poly(A)-coupled		 P
IPI
SceS000001501
GO:0030847 termination of RNA polymerase II transcription,
poly(A)-independent		 P
IPI
SceS000001501
GO:0031123 RNA 3'-end processing P
RCA
SceS000001501
GO:0031124 mRNA 3'-end processing P
IMP
SceS000001501
GO:0031126 snoRNA 3'-end processing P
IMP
SceS000001501
GO:0034729 histone H3-K79 methylation P
IMP
SceS000001501
GO:0040007 growth P
IMP
CelWBGene00016374
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00016374
GO:0051013 microtubule severing P
ISS
DmeFBgn0032030
GO:0051568 histone H3-K4 methylation P
IDA
SceS000001501
IMP
SpoSPBC18H10.06c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
42951

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) WDR82 GI:147904340
Pan troglodytes (Ptr) WDR82 GI:114587264
Canis familiaris (Cfa) WDR82 GI:73985333
Mus musculus (Mmu) Wdr82
(MGI:1924555)		 GI:51765108 B2RXQ8
Gallus gallus (Gga) WDR82 GI:57524933
Drosophila melanogaster (Dme) CG17293
(FBgn0032030)		 GI:19920938
Anopheles gambiae (Aga) AgaP_AGAP009700 GI:58391653
Caenorhabditis elegans (Cel) C33H5.7
(CE04150;
WBGene00016374)		 GI:17538994 Q18403
Schizosaccharomyces pombe (Spo) swd2
(SPBC18H10.06c)		 GI:19112522 O60137
Saccharomyces cerevisiae (Sce) SWD2
(S000001501)		 GI:6322834 P36104
Kluyveromyces lactis (Kla) KLLA0E18139g GI:50309511
Eremothecium gossypii (Ego) AGOS_ACL099W GI:45185589
Magnaporthe grisea (Mgr) MGG_06406 GI:39977007
Neurospora crassa (Ncr) NCU07885.1 GI:32416226
Arabidopsis thaliana (Ath) AT5G66240 GI:18425050
Oryza sativa (Osa) Os07g0589400 GI:115473103
Plasmodium falciparum (Pfa) PFL2105c GI:124806760


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPBC18H10.06c
GO:0005575 cellular_component C
ND
MmuMGI:1924555
GO:0005829 cytosol C
IDA
SpoSPBC18H10.06c
GO:0005847 mRNA cleavage and polyadenylation specificity
factor complex		 C
IPI
SceS000001501
GO:0008352 katanin complex C
ISS
DmeFBgn0032030
GO:0035097 histone methyltransferase complex C
IDA
HsaWDR82
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPBC18H10.06c
IPI
SceS000001501
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt5g66240
GO:0000166 nucleotide binding F
ISS
AthAt5g66240
GO:0003674 molecular_function F
ND
MmuMGI:1924555
SpoSPBC18H10.06c
GO:0042800 histone methyltransferase activity (H3-K4
specific)		 F
IDA
HsaWDR82
SceS000001501
GO:0000003 reproduction P
IMP
CelWBGene00016374
GO:0000723 telomere maintenance P
IMP
SceS000001501
GO:0002119 nematode larval development P
IMP
CelWBGene00016374
GO:0006338 chromatin remodeling P
IC
SpoSPBC18H10.06c
GO:0006353 transcription termination P
RCA
SceS000001501
GO:0008150 biological_process P
ND
MmuMGI:1924555
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00016374
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016374
GO:0016074 snoRNA metabolic process P
RCA
SceS000001501
GO:0016571 histone methylation P
IMP
SpoSPBC18H10.06c
GO:0030846 termination of RNA polymerase II transcription,
poly(A)-coupled		 P
IPI
SceS000001501
GO:0030847 termination of RNA polymerase II transcription,
poly(A)-independent		 P
IPI
SceS000001501
GO:0031123 RNA 3'-end processing P
RCA
SceS000001501
GO:0031124 mRNA 3'-end processing P
IMP
SceS000001501
GO:0031126 snoRNA 3'-end processing P
IMP
SceS000001501
GO:0034729 histone H3-K79 methylation P
IMP
SceS000001501
GO:0040007 growth P
IMP
CelWBGene00016374
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00016374
GO:0051013 microtubule severing P
ISS
DmeFBgn0032030
GO:0051568 histone H3-K4 methylation P
IDA
HsaWDR82
SceS000001501
IMP
SpoSPBC18H10.06c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1754

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga11909 ENSANGP00000013183
Ashbya gossypii (Ago) ago950 ACL099W
Arabidopsis thaliana (Ath) ath23660 At5g14530.1
Arabidopsis thaliana (Ath) ath28795 At5g66240.1
Arabidopsis thaliana (Ath) ath28796 At5g66240.2
Caenorhabditis elegans (Cel) cel3348 C33H5.7
(CE04150;
WBGene00016374)
Candida glabrata (Cgl) cgl4500 CAGL0L09757g
Cryptococcus neoformans (Cne) cne5173 179.m00019
Dictyostelium discoideum (Ddi) ddi6593 DDB0218126
Debaryomyces hansenii (Dha) dha5602 DEHA0F27214g
Drosophila melanogaster (Dme) dme1434 CG17293-PA
(FBgn0032030)
Danio rerio (Dre) dre20687 ENSDARP00000019685
(wdr82)		 Q6TEM7
Encephalitozoon cuniculi (Ecu) ecu875 19074237
Takifugu rubripes (Fru) fru30183 SINFRUP00000127377
Takifugu rubripes (Fru) fru28069 SINFRUP00000131307
Takifugu rubripes (Fru) fru28070 SINFRUP00000176732
Gallus gallus (Gga) gga5037 ENSGALP00000006328
Homo sapiens (Hsa) hsa22806 ENSP00000328139
Kluyveromyces lactis (Kla) kla3764 KLLA0E18139g
Mus musculus (Mmu) mmu28204 ENSMUSP00000020490
(MGI:1924555)		 Q8BFQ4
Neurospora crassa (Ncr) ncr7681 NCU07885.2
Oryza sativa (Osa) osa3859 2065.m00096
Oryza sativa (Osa) osa70516 7144.m00074
Oryza sativa (Osa) osa77826 7328.m00136
Plasmodium falciparum (Pfa) pfa5202 PFL2105c
Saccharomyces cerevisiae (Sce) sce3681 YKL018W
(S000001501)
Schizosaccharomyces pombe (Spo) spo2749 SPAC824.04 Q9UT39
Schizosaccharomyces pombe (Spo) spo938 SPBC18H10.06c O60137
Yarrowia lipolytica (Yli) yli6239 YALI0F21263g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPBC18H10.06c
GO:0005575 cellular_component C
ND
MmuMGI:1924555
GO:0005634 nucleus C
IDA
SpoSPAC824.04
GO:0005829 cytosol C
IDA
SpoSPAC824.04
SPBC18H10.06c
GO:0005847 mRNA cleavage and polyadenylation specificity
factor complex		 C
IDA
SpoSPAC824.04
IPI
SceS000001501
GO:0008352 katanin complex C
ISS
DmeFBgn0032030
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPBC18H10.06c
IPI
SceS000001501
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt5g14530
At5g66240
GO:0000166 nucleotide binding F
ISS
AthAt5g66240
At5g14530
GO:0003674 molecular_function F
ND
MmuMGI:1924555
SpoSPAC824.04
SPBC18H10.06c
GO:0042800 histone methyltransferase activity (H3-K4
specific)		 F
IDA
SceS000001501
GO:0000003 reproduction P
IMP
CelWBGene00016374
GO:0000723 telomere maintenance P
IMP
SceS000001501
GO:0002119 nematode larval development P
IMP
CelWBGene00016374
GO:0006338 chromatin remodeling P
IC
SpoSPBC18H10.06c
GO:0006353 transcription termination P
RCA
SceS000001501
GO:0006378 mRNA polyadenylation P
IC
SpoSPAC824.04
GO:0006379 mRNA cleavage P
IC
SpoSPAC824.04
GO:0008150 biological_process P
ND
AthAt5g14530
MmuMGI:1924555
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00016374
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00016374
GO:0016074 snoRNA metabolic process P
RCA
SceS000001501
GO:0016571 histone methylation P
IMP
SpoSPBC18H10.06c
GO:0030846 termination of RNA polymerase II transcription,
poly(A)-coupled		 P
IPI
SceS000001501
GO:0030847 termination of RNA polymerase II transcription,
poly(A)-independent		 P
IPI
SceS000001501
GO:0031123 RNA 3'-end processing P
RCA
SceS000001501
GO:0031124 mRNA 3'-end processing P
IMP
SceS000001501
GO:0031126 snoRNA 3'-end processing P
IMP
SceS000001501
GO:0034729 histone H3-K79 methylation P
IMP
SceS000001501
GO:0040007 growth P
IMP
CelWBGene00016374
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00016374
GO:0051013 microtubule severing P
ISS
DmeFBgn0032030
GO:0051568 histone H3-K4 methylation P
IDA
SceS000001501
IMP
SpoSPBC18H10.06c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC18H10.06c
(O60137)		 YKL018W
(S000001501)
SPAC824.04
(Q9UT39)		 YKL018W
(S000001501)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPBC18H10.06c
GO:0005634 nucleus C
IDA
SpoSPAC824.04
GO:0005829 cytosol C
IDA
SpoSPAC824.04
SPBC18H10.06c
GO:0005847 mRNA cleavage and polyadenylation specificity
factor complex		 C
IDA
SpoSPAC824.04
IPI
SceS000001501
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPBC18H10.06c
IPI
SceS000001501
GO:0003674 molecular_function F
ND
SpoSPAC824.04
SPBC18H10.06c
GO:0042800 histone methyltransferase activity (H3-K4
specific)		 F
IDA
SceS000001501
GO:0000723 telomere maintenance P
IMP
SceS000001501
GO:0006338 chromatin remodeling P
IC
SpoSPBC18H10.06c
GO:0006353 transcription termination P
RCA
SceS000001501
GO:0006378 mRNA polyadenylation P
IC
SpoSPAC824.04
GO:0006379 mRNA cleavage P
IC
SpoSPAC824.04
GO:0016074 snoRNA metabolic process P
RCA
SceS000001501
GO:0016571 histone methylation P
IMP
SpoSPBC18H10.06c
GO:0030846 termination of RNA polymerase II transcription,
poly(A)-coupled		 P
IPI
SceS000001501
GO:0030847 termination of RNA polymerase II transcription,
poly(A)-independent		 P
IPI
SceS000001501
GO:0031123 RNA 3'-end processing P
RCA
SceS000001501
GO:0031124 mRNA 3'-end processing P
IMP
SceS000001501
GO:0031126 snoRNA 3'-end processing P
IMP
SceS000001501
GO:0034729 histone H3-K79 methylation P
IMP
SceS000001501
GO:0051568 histone H3-K4 methylation P
IDA
SceS000001501
IMP
SpoSPBC18H10.06c

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