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Search term: YKL022C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CDC16
SGD link S000001505
Alternative ID YKL022C
Description Subunit of the anaphase-promoting complex/cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; required for sporulation
Synonyms YKL022C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1173 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Anaphase-promoting complex (APC), Cdc16 subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g78770 GI:3834317
Caenorhabditis elegans (Cel) CE01548
(WBGene00001281)		 GI:17532855 Q09536
Drosophila melanogaster (Dme) 7300983
(FBgn0025781)		 GI:17137612 Q9VCN6
Homo sapiens (Hsa) Hs14110371 GI:14110371
Saccharomyces cerevisiae (Sce) YKL022c
(S000001505)		 GI:6322830 P09798
Schizosaccharomyces pombe (Spo) SPAC6F12.15c GI:19114213 P41889
Encephalitozoon cuniculi (Ecu) ECU06g0150 GI:19074265 Q8SRT6
Arabidopsis thaliana (Ath) At1g78770 GI:3834317
Caenorhabditis elegans (Cel) CE01548
(WBGene00001281)		 GI:17532855 Q09536
Drosophila melanogaster (Dme) 7300983
(FBgn0025781)		 GI:17137612 Q9VCN6
Homo sapiens (Hsa) Hs14110371 GI:14110371
Saccharomyces cerevisiae (Sce) YKL022c
(S000001505)		 GI:6322830 P09798
Schizosaccharomyces pombe (Spo) SPAC6F12.15c GI:19114213 P41889
Encephalitozoon cuniculi (Ecu) ECU06g0150 GI:19074265 Q8SRT6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g78770
GO:0005680 anaphase-promoting complex C
IDA
SceS000001505
SpoSPAC6F12.15c
ISS
DmeFBgn0025781
NAS
DmeFBgn0025781
GO:0005829 cytosol C
IDA
SpoSPAC6F12.15c
GO:0004842 ubiquitin-protein ligase activity F
ISS
DmeFBgn0025781
TAS
SceS000001505
GO:0005515 protein binding F
IPI
SpoSPAC6F12.15c
TAS
SceS000001505
GO:0000003 reproduction P
IMP
CelWBGene00001281
GO:0000022 mitotic spindle elongation P
TAS
SceS000001505
GO:0000070 mitotic sister chromatid segregation P
TAS
SceS000001505
GO:0000090 mitotic anaphase P
NAS
DmeFBgn0025781
GO:0000278 mitotic cell cycle P
IMP
SceS000001505
GO:0007049 cell cycle P
IMP
DmeFBgn0025781
ISS
AthAt1g78770
GO:0007067 mitosis P
IMP
CelWBGene00001281
GO:0007091 mitotic metaphase/anaphase transition P
TAS
SceS000001505
GO:0007126 meiosis P
IMP
CelWBGene00001281
GO:0008054 cyclin catabolic process P
IC
SpoSPAC6F12.15c
TAS
SceS000001505
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001281
GO:0010087 phloem or xylem histogenesis P
IMP
AthAt1g78770
GO:0016567 protein ubiquitination P
IC
SpoSPAC6F12.15c
IPI
SceS000001505
GO:0030071 regulation of mitotic metaphase/anaphase
transition		 P
IMP
DmeFBgn0025781
SpoSPAC6F12.15c
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000001505
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
IC
SpoSPAC6F12.15c
IDA
SceS000001505
IPI
SceS000001505
GO:0032297 negative regulation of DNA-dependent DNA
replication initiation		 P
IMP
SceS000001505
GO:0032875 regulation of DNA endoreduplication P
IMP
AthAt1g78770
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00001281

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2899

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CDC16 GI:118402578
Pan troglodytes (Ptr) CDC16 GI:114692493
Canis familiaris (Cfa) CDC16 GI:73989523
Mus musculus (Mmu) Cdc16
(MGI:1917207)		 GI:68448515 Q3TI84
Rattus norvegicus (Rno) Cdc16
(RGD:1305076)		 GI:67078528
Gallus gallus (Gga) CDC16 GI:57525501
Drosophila melanogaster (Dme) cdc16
(FBgn0025781)		 GI:17137612 Q9VCN6
Anopheles gambiae (Aga) AgaP_AGAP004623 GI:158293857
Schizosaccharomyces pombe (Spo) cut9
(SPAC6F12.15c)		 GI:19114213 P41889
Saccharomyces cerevisiae (Sce) CDC16
(S000001505)		 GI:6322830 P09798
Kluyveromyces lactis (Kla) KLLA0E07986g GI:50308617
Eremothecium gossypii (Ego) AGOS_ACR168W GI:45185854
Magnaporthe grisea (Mgr) MGG_07440 GI:39972277
Neurospora crassa (Ncr) NCU01377.1 GI:32412780
Arabidopsis thaliana (Ath) AT1G78770 GI:18412102
Oryza sativa (Osa) Os03g0236900 GI:115451781


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g78770
GO:0005634 nucleus C
IDA
MmuMGI:1917207
GO:0005654 nucleoplasm C
EXP
HsaCDC16
GO:0005680 anaphase-promoting complex C
IDA
HsaCDC16
SceS000001505
SpoSPAC6F12.15c
ISS
DmeFBgn0025781
NAS
DmeFBgn0025781
GO:0005737 cytoplasm C
IDA
HsaCDC16
GO:0005813 centrosome C
IDA
HsaCDC16
ISO
MmuMGI:1917207
GO:0005819 spindle C
TAS
HsaCDC16
GO:0005829 cytosol C
EXP
HsaCDC16
IDA
SpoSPAC6F12.15c
GO:0005876 spindle microtubule C
IDA
HsaCDC16
ISO
MmuMGI:1917207
GO:0004842 ubiquitin-protein ligase activity F
ISS
DmeFBgn0025781
TAS
SceS000001505
GO:0005515 protein binding F
IPI
MmuMGI:1917207
SpoSPAC6F12.15c
TAS
SceS000001505
GO:0000022 mitotic spindle elongation P
TAS
SceS000001505
GO:0000070 mitotic sister chromatid segregation P
TAS
SceS000001505
GO:0000090 mitotic anaphase P
NAS
DmeFBgn0025781
GO:0000278 mitotic cell cycle P
IMP
SceS000001505
GO:0007049 cell cycle P
IMP
DmeFBgn0025781
ISS
AthAt1g78770
GO:0007067 mitosis P
TAS
HsaCDC16
GO:0007088 regulation of mitosis P
TAS
HsaCDC16
GO:0007091 mitotic metaphase/anaphase transition P
TAS
SceS000001505
GO:0008054 cyclin catabolic process P
IC
SpoSPAC6F12.15c
TAS
SceS000001505
GO:0008150 biological_process P
ND
MmuMGI:1917207
GO:0008283 cell proliferation P
TAS
HsaCDC16
GO:0010087 phloem or xylem histogenesis P
IMP
AthAt1g78770
GO:0016567 protein ubiquitination P
IC
SpoSPAC6F12.15c
IPI
SceS000001505
GO:0030071 regulation of mitotic metaphase/anaphase
transition		 P
IMP
DmeFBgn0025781
SpoSPAC6F12.15c
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000001505
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
EXP
HsaCDC16
IC
SpoSPAC6F12.15c
IDA
SceS000001505
IPI
SceS000001505
GO:0032297 negative regulation of DNA-dependent DNA
replication initiation		 P
IMP
SceS000001505
GO:0032875 regulation of DNA endoreduplication P
IMP
AthAt1g78770
GO:0051436 negative regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaCDC16
GO:0051437 positive regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaCDC16
GO:0070979 protein K11-linked ubiquitination P
IDA
HsaCDC16

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2754

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7186 ENSANGP00000020883
Anopheles gambiae (Aga) aga7187 ENSANGP00000026377
Ashbya gossypii (Ago) ago1215 ACR168W
Arabidopsis thaliana (Ath) ath7228 At1g78770.1
Caenorhabditis elegans (Cel) cel5869 F10B5.6
(CE01548;
WBGene00001281)
Candida glabrata (Cgl) cgl4503 CAGL0L09823g
Cryptococcus neoformans (Cne) cne3185 167.m03526
Dictyostelium discoideum (Ddi) ddi7127 DDB0186872
Debaryomyces hansenii (Dha) dha1776 DEHA0C07876g
Drosophila melanogaster (Dme) dme13997 CG6759-PA
(FBgn0025781)
Danio rerio (Dre) dre25478 ENSDARP00000033324
Encephalitozoon cuniculi (Ecu) ecu1492 19074265
Takifugu rubripes (Fru) fru31146 SINFRUP00000139365
Gallus gallus (Gga) gga2658 ENSGALP00000027097
(CDC16)		 Q5ZIZ9
Homo sapiens (Hsa) hsa9096 ENSP00000252457
(CDC16)		 Q13042-2
Homo sapiens (Hsa) hsa9098 ENSP00000252458
(CDC16)		 Q13042-3
Homo sapiens (Hsa) hsa9097 ENSP00000348554
(CDC16)		 Q13042-1
Kluyveromyces lactis (Kla) kla3310 KLLA0E07986g
Mus musculus (Mmu) mmu25659 ENSMUSP00000047950
(MGI:1917207)		 Q8R349
Neurospora crassa (Ncr) ncr1336 NCU01377.2
Oryza sativa (Osa) osa61843 6607.m00127
Oryza sativa (Osa) osa67612 6962.m00084
Rattus norvegicus (Rno) rno12752 ENSRNOP00000023736
(RGD:1305076)		 Q4V884
Saccharomyces cerevisiae (Sce) sce3685 YKL022C
(S000001505)
Schizosaccharomyces pombe (Spo) spo1123 SPAC6F12.15c P41889
Yarrowia lipolytica (Yli) yli1381 YALI0B15378g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g78770
GO:0005634 nucleus C
IDA
MmuMGI:1917207
GO:0005680 anaphase-promoting complex C
IDA
SceS000001505
SpoSPAC6F12.15c
ISS
DmeFBgn0025781
NAS
DmeFBgn0025781
GO:0005813 centrosome C
ISO
MmuMGI:1917207
GO:0005829 cytosol C
IDA
SpoSPAC6F12.15c
GO:0005876 spindle microtubule C
ISO
MmuMGI:1917207
GO:0004842 ubiquitin-protein ligase activity F
ISS
DmeFBgn0025781
TAS
SceS000001505
GO:0005515 protein binding F
IPI
MmuMGI:1917207
SpoSPAC6F12.15c
TAS
SceS000001505
GO:0000003 reproduction P
IMP
CelWBGene00001281
GO:0000022 mitotic spindle elongation P
TAS
SceS000001505
GO:0000070 mitotic sister chromatid segregation P
TAS
SceS000001505
GO:0000090 mitotic anaphase P
NAS
DmeFBgn0025781
GO:0000278 mitotic cell cycle P
IMP
SceS000001505
GO:0007049 cell cycle P
IMP
DmeFBgn0025781
ISS
AthAt1g78770
GO:0007067 mitosis P
IMP
CelWBGene00001281
GO:0007091 mitotic metaphase/anaphase transition P
TAS
SceS000001505
GO:0007126 meiosis P
IMP
CelWBGene00001281
GO:0008054 cyclin catabolic process P
IC
SpoSPAC6F12.15c
TAS
SceS000001505
GO:0008150 biological_process P
ND
MmuMGI:1917207
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001281
GO:0010087 phloem or xylem histogenesis P
IMP
AthAt1g78770
GO:0016567 protein ubiquitination P
IC
SpoSPAC6F12.15c
IPI
SceS000001505
GO:0030071 regulation of mitotic metaphase/anaphase
transition		 P
IMP
DmeFBgn0025781
SpoSPAC6F12.15c
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000001505
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
IC
SpoSPAC6F12.15c
IDA
SceS000001505
IPI
SceS000001505
GO:0032297 negative regulation of DNA-dependent DNA
replication initiation		 P
IMP
SceS000001505
GO:0032875 regulation of DNA endoreduplication P
IMP
AthAt1g78770
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00001281

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC6F12.15c
(P41889)		 YKL022C
(S000001505)