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Search term: YKL040C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NFU1
SGD link S000001523
Alternative ID YKL040C
Description Protein involved in iron metabolism in mitochondria; similar to NifU, which is a protein required for the maturation of the Fe/S clusters of nitrogenase in nitrogen-fixing bacteria
Synonyms YKL040C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2358 AC-HYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING NifU-like domain-containing proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g51390 GI:15223842
Arabidopsis thaliana (Ath) At3g20970 GI:18402817
Arabidopsis thaliana (Ath) At4g01940 GI:4558563
Arabidopsis thaliana (Ath) At4g25910 GI:7485833
Arabidopsis thaliana (Ath) At5g49940_1 GI:8777425
Caenorhabditis elegans (Cel) CE06292
(WBGene00003064)
GI:17541876 Q21915
Homo sapiens (Hsa) Hs7661720 GI:7661720
Saccharomyces cerevisiae (Sce) YKL040c
(S000001523)
GI:6322811 P32860
Schizosaccharomyces pombe (Spo) SPBC1709.19c GI:19112244 Q9UUB8


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt3g20970
At1g51390
SceS000001523
SpoSPBC1709.19c
ISS
AthAt3g20970
At1g51390
GO:0005759 mitochondrial matrix C
IDA
SceS000001523
ISS
SpoSPBC1709.19c
GO:0009507 chloroplast C
IDA
AthAt5g49940
At4g01940
At4g25910
ISS
AthAt4g25910
GO:0003674 molecular_function F
ND
SceS000001523
GO:0005198 structural molecule activity F
TAS
AthAt3g20970
At5g49940
At4g25910
At4g01940
At1g51390
GO:0005507 copper ion binding F
IDA
AthAt1g51390
GO:0005524 ATP binding F
IDA
AthAt1g51390
GO:0000003 reproduction P
IMP
CelWBGene00003064
GO:0002119 nematode larval development P
IMP
CelWBGene00003064
GO:0006629 lipid metabolic process P
IMP
CelWBGene00003064
GO:0006879 cellular iron ion homeostasis P
IMP
SceS000001523
ISS
SceS000001523
SpoSPBC1709.19c
GO:0006880 intracellular sequestering of iron
ion
P
IMP
SceS000001523
GO:0009658 chloroplast organization P
IMP
AthAt5g49940
ISS
AthAt4g01940
At4g25910
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00003064
GO:0016226 iron-sulfur cluster assembly P
IGI
AthAt4g01940
At3g20970
At5g49940
At4g25910
At1g51390
IMP
AthAt5g49940
SceS000001523
ISS
AthAt3g20970
At4g01940
At1g51390
At4g25910
GO:0019915 lipid storage P
IMP
CelWBGene00003064
GO:0040007 growth P
IMP
CelWBGene00003064
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003064

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6369

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) NFU1 GI:50593021
Pan troglodytes (Ptr) NFU1 GI:55596270
Canis familiaris (Cfa) NFU1 GI:73970249
Mus musculus (Mmu) Nfu1
(MGI:1913290)
GI:9910264 Q9QZ23
Rattus norvegicus (Rno) Nfu1 GI:109472303
Gallus gallus (Gga) NFU1 GI:57529447
Drosophila melanogaster (Dme) CG32857
(FBgn0052857)
GI:24643765
Drosophila melanogaster (Dme) CG32500
(FBgn0052500)
GI:45551492
Drosophila melanogaster (Dme) CG33502
(FBgn0053502)
GI:45556188
Anopheles gambiae (Aga) AgaP_AGAP000598 GI:158288625
Caenorhabditis elegans (Cel) lpd-8
(CE06292;
WBGene00003064)
GI:17541876 Q21915
Schizosaccharomyces pombe (Spo) SPBC1709.19c GI:19112244 Q9UUB8
Saccharomyces cerevisiae (Sce) NFU1
(S000001523)
GI:6322811 P32860
Kluyveromyces lactis (Kla) KLLA0F25476g GI:50312363
Eremothecium gossypii (Ego) AGOS_ABR045W GI:45185274
Magnaporthe grisea (Mgr) MGG_06993 GI:145605625
Neurospora crassa (Ncr) NCU01779.1 GI:32415477
Arabidopsis thaliana (Ath) NFU4 GI:18402817
Arabidopsis thaliana (Ath) NFU5 GI:42562675
Oryza sativa (Osa) Os05g0155300 GI:115462181


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
DmeFBgn0053502
GO:0005634 nucleus C
IDA
HsaNFU1
GO:0005739 mitochondrion C
IDA
AthNFU4
NFU5
HsaNFU1
MmuMGI:1913290
SceS000001523
SpoSPBC1709.19c
ISS
AthNFU4
NFU5
GO:0005759 mitochondrial matrix C
IDA
SceS000001523
ISS
SpoSPBC1709.19c
GO:0005829 cytosol C
IDA
HsaNFU1
ISA
MmuMGI:1913290
GO:0003674 molecular_function F
ND
DmeFBgn0053502
SceS000001523
GO:0003676 nucleic acid binding F
ISS
DmeFBgn0052857
GO:0005198 structural molecule activity F
TAS
AthNFU4
NFU5
GO:0005506 iron ion binding F
IDA
HsaNFU1
GO:0005507 copper ion binding F
IDA
AthNFU5
GO:0005515 protein binding F
IPI
HsaNFU1
MmuMGI:1913290
GO:0005524 ATP binding F
IDA
AthNFU5
ISS
DmeFBgn0052857
GO:0008026 ATP-dependent helicase activity F
ISS
DmeFBgn0052857
GO:0051539 4 iron, 4 sulfur cluster binding F
IDA
HsaNFU1
GO:0000003 reproduction P
IMP
CelWBGene00003064
GO:0002119 nematode larval development P
IMP
CelWBGene00003064
GO:0006629 lipid metabolic process P
IMP
CelWBGene00003064
GO:0006879 cellular iron ion homeostasis P
IMP
SceS000001523
ISS
SceS000001523
SpoSPBC1709.19c
GO:0006880 intracellular sequestering of iron
ion
P
IMP
SceS000001523
GO:0008150 biological_process P
ND
DmeFBgn0053502
MmuMGI:1913290
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00003064
GO:0016226 iron-sulfur cluster assembly P
IDA
HsaNFU1
IGI
AthNFU4
NFU5
IMP
SceS000001523
ISS
AthNFU4
NFU5
GO:0019915 lipid storage P
IMP
CelWBGene00003064
GO:0040007 growth P
IMP
CelWBGene00003064
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003064

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1446

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga15244 ENSANGP00000019230
Ashbya gossypii (Ago) ago636 ABR045W
Arabidopsis thaliana (Ath) ath4408 At1g51390.1
Arabidopsis thaliana (Ath) ath14396 At3g20970.1
Caenorhabditis elegans (Cel) cel13805 R10H10.1
(CE06292;
WBGene00003064)
Candida glabrata (Cgl) cgl4154 CAGL0L01859g
Cryptococcus neoformans (Cne) cne4281 177.m03038
Dictyostelium discoideum (Ddi) ddi9413 DDB0186594
Debaryomyces hansenii (Dha) dha2184 DEHA0C17028g
Debaryomyces hansenii (Dha) dha6108 DEHA0G09207g
Drosophila melanogaster (Dme) dme18932 CG32500-PA
(FBgn0052500)
Drosophila melanogaster (Dme) dme18929 CG32857-PA
(FBgn0052857)
Drosophila melanogaster (Dme) dme18926 CG33502-PA
(FBgn0053502)
Danio rerio (Dre) dre9992 ENSDARP00000008117
Danio rerio (Dre) dre29740 ENSDARP00000011966
(zgc:110319)
Q6P002
Escherichia coli (Eco) eco3295 16131290
Takifugu rubripes (Fru) fru19771 SINFRUP00000146915
Takifugu rubripes (Fru) fru28284 SINFRUP00000165353
Gallus gallus (Gga) gga12661 ENSGALP00000000045
(NFU1)
Q5ZHL5
Homo sapiens (Hsa) hsa17933 ENSP00000306965
(NFU1)
Kluyveromyces lactis (Kla) kla5215 KLLA0F25476g
Mus musculus (Mmu) mmu22268 ENSMUSP00000032060
(MGI:1913290)
Neurospora crassa (Ncr) ncr1731 NCU01779.2
Oryza sativa (Osa) osa15816 3000.m00110
Plasmodium falciparum (Pfa) pfa4834 PFI1835c
Rattus norvegicus (Rno) rno21783 ENSRNOP00000024884
(RGD:1307823)
Saccharomyces cerevisiae (Sce) sce3704 YKL040C
(S000001523)
Schizosaccharomyces pombe (Spo) spo2171 SPBC1709.19c Q9UUB8
Yarrowia lipolytica (Yli) yli755 YALI0B00264g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
DmeFBgn0053502
GO:0005739 mitochondrion C
IDA
AthAt3g20970
At1g51390
MmuMGI:1913290
SceS000001523
SpoSPBC1709.19c
ISS
AthAt3g20970
At1g51390
GO:0005759 mitochondrial matrix C
IDA
SceS000001523
ISS
SpoSPBC1709.19c
GO:0005829 cytosol C
ISA
MmuMGI:1913290
GO:0003674 molecular_function F
ND
DmeFBgn0053502
SceS000001523
GO:0003676 nucleic acid binding F
ISS
DmeFBgn0052857
GO:0005198 structural molecule activity F
TAS
AthAt3g20970
At1g51390
GO:0005507 copper ion binding F
IDA
AthAt1g51390
GO:0005515 protein binding F
IPI
MmuMGI:1913290
GO:0005524 ATP binding F
IDA
AthAt1g51390
ISS
DmeFBgn0052857
GO:0008026 ATP-dependent helicase activity F
ISS
DmeFBgn0052857
GO:0000003 reproduction P
IMP
CelWBGene00003064
GO:0002119 nematode larval development P
IMP
CelWBGene00003064
GO:0006629 lipid metabolic process P
IMP
CelWBGene00003064
GO:0006879 cellular iron ion homeostasis P
IMP
SceS000001523
ISS
SceS000001523
SpoSPBC1709.19c
GO:0006880 intracellular sequestering of iron
ion
P
IMP
SceS000001523
GO:0008150 biological_process P
ND
DmeFBgn0053502
MmuMGI:1913290
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00003064
GO:0016226 iron-sulfur cluster assembly P
IGI
AthAt3g20970
At1g51390
IMP
SceS000001523
ISS
AthAt3g20970
At1g51390
GO:0019915 lipid storage P
IMP
CelWBGene00003064
GO:0040007 growth P
IMP
CelWBGene00003064
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003064

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC1709.19c
(Q9UUB8)
YKL040C
(S000001523)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001523
SpoSPBC1709.19c
GO:0005759 mitochondrial matrix C
IDA
SceS000001523
ISS
SpoSPBC1709.19c
GO:0003674 molecular_function F
ND
SceS000001523
GO:0006879 cellular iron ion homeostasis P
IMP
SceS000001523
ISS
SceS000001523
SpoSPBC1709.19c
GO:0006880 intracellular sequestering of iron
ion
P
IMP
SceS000001523
GO:0016226 iron-sulfur cluster assembly P
IMP
SceS000001523

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Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk