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Search term: YKL058W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TOA2
SGD link S000001541
Alternative ID YKL058W
Description TFIIA small subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; homologous to smallest subunit of human and Drosophila TFIIA
Synonyms YKL058W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3463 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Transcription initiation factor IIA, gamma subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g24440 GI:15233829
Caenorhabditis elegans (Cel) CE26429
(WBGene00015150)
GI:17551834 Q9BIB4
Caenorhabditis elegans (Cel) CE26630
(WBGene00013736)
GI:17556689 Q9NEX2
Drosophila melanogaster (Dme) 7290110 GI:20140919
Drosophila melanogaster (Dme) 7301064
(FBgn0013347)
GI:17738155
Homo sapiens (Hsa) Hs22048109 GI:22048109
Homo sapiens (Hsa) Hs4758486
(GTF2A2)
GI:4758486 P52657
Saccharomyces cerevisiae (Sce) YKL058w
(S000001541)
GI:6322792 P32774
Schizosaccharomyces pombe (Spo) SPCC553.11c GI:19075263 O74948
Encephalitozoon cuniculi (Ecu) ECU02g0450 GI:19073966 Q8SSH6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC553.11c
NAS
DmeFBgn0013347
GO:0005654 nucleoplasm C
EXP
HsaGTF2A2
GO:0005672 transcription factor TFIIA complex C
IDA
HsaGTF2A2
SceS000001541
ISS
AthAt4g24440
DmeFBgn0013347
SpoSPCC553.11c
GO:0005829 cytosol C
IDA
SpoSPCC553.11c
GO:0003702 RNA polymerase II transcription factor
activity
F
IDA
HsaGTF2A2
ISS
AthAt4g24440
GO:0003713 transcription coactivator activity F
IDA
HsaGTF2A2
GO:0005515 protein binding F
IPI
HsaGTF2A2
GO:0008134 transcription factor binding F
IPI
HsaGTF2A2
GO:0016251 general RNA polymerase II transcription factor
activity
F
IDA
HsaGTF2A2
GTF2A2
SceS000001541
ISS
DmeFBgn0013347
SpoSPCC553.11c
GO:0017025 TATA-binding protein binding F
IPI
HsaGTF2A2
GO:0042802 identical protein binding F
IPI
HsaGTF2A2
GO:0042803 protein homodimerization activity F
IPI
HsaGTF2A2
GO:0046982 protein heterodimerization activity F
IPI
HsaGTF2A2
GO:0006357 regulation of transcription from RNA polymerase II
promoter
P
NAS
DmeFBgn0013347
GO:0006367 transcription initiation from RNA polymerase II
promoter
P
EXP
HsaGTF2A2
IDA
SceS000001541
ISS
AthAt4g24440
DmeFBgn0013347
SpoSPCC553.11c
GO:0006368 RNA elongation from RNA polymerase II
promoter
P
EXP
HsaGTF2A2
GO:0010552 positive regulation of gene-specific transcription
from RNA polymerase II promoter
P
IDA
HsaGTF2A2
GO:0032568 general transcription from RNA polymerase II
promoter
P
IDA
HsaGTF2A2
GO:0045449 regulation of transcription P
ISS
SpoSPCC553.11c
GO:0051091 positive regulation of transcription factor
activity
P
IDA
HsaGTF2A2
GO:0051123 RNA polymerase II transcriptional preinitiation
complex assembly
P
IDA
HsaGTF2A2

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3304

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GTF2A2 GI:4758486 P52657
Pan troglodytes (Ptr) GTF2A2 GI:114657364
Canis familiaris (Cfa) GTF2A2 GI:57108247
Mus musculus (Mmu) Gtf2a2
(MGI:1933289)
GI:87299617 Q05C74
Rattus norvegicus (Rno) Gtf2a2
(RGD:620720)
GI:16758064
Gallus gallus (Gga) GTF2A2 GI:118095646
Drosophila melanogaster (Dme) TfIIA-S
(FBgn0013347)
GI:17738155
Anopheles gambiae (Aga) AgaP_AGAP004370 GI:158292095
Caenorhabditis elegans (Cel) Y111B2A.13
(CE26630;
WBGene00013736)
GI:17556689 Q9NEX2
Schizosaccharomyces pombe (Spo) SPCC553.11c GI:19075263 O74948
Saccharomyces cerevisiae (Sce) TOA2
(S000001541)
GI:6322792 P32774
Kluyveromyces lactis (Kla) KLLA0C12815g GI:50305621
Eremothecium gossypii (Ego) AGOS_ABR071W GI:45185300
Magnaporthe grisea (Mgr) MGG_06107 GI:39975933
Neurospora crassa (Ncr) NCU09748.1 GI:32419909
Arabidopsis thaliana (Ath) AT4G24440 GI:15233829
Oryza sativa (Osa) Os05g0107700 GI:115461653
Oryza sativa (Osa) Os01g0970500 GI:115442493


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC553.11c
NAS
DmeFBgn0013347
GO:0005654 nucleoplasm C
EXP
HsaGTF2A2
GO:0005672 transcription factor TFIIA complex C
IDA
HsaGTF2A2
SceS000001541
ISS
AthAt4g24440
DmeFBgn0013347
SpoSPCC553.11c
GO:0005829 cytosol C
IDA
SpoSPCC553.11c
GO:0003702 RNA polymerase II transcription factor
activity
F
IDA
HsaGTF2A2
ISS
AthAt4g24440
GO:0003713 transcription coactivator activity F
IDA
HsaGTF2A2
GO:0005515 protein binding F
IPI
HsaGTF2A2
GO:0008134 transcription factor binding F
IPI
HsaGTF2A2
GO:0016251 general RNA polymerase II transcription factor
activity
F
IDA
HsaGTF2A2
GTF2A2
SceS000001541
ISS
DmeFBgn0013347
SpoSPCC553.11c
GO:0017025 TATA-binding protein binding F
IPI
HsaGTF2A2
GO:0042802 identical protein binding F
IPI
HsaGTF2A2
GO:0042803 protein homodimerization activity F
IPI
HsaGTF2A2
GO:0046982 protein heterodimerization activity F
IPI
HsaGTF2A2
GO:0006357 regulation of transcription from RNA polymerase II
promoter
P
NAS
DmeFBgn0013347
GO:0006367 transcription initiation from RNA polymerase II
promoter
P
EXP
HsaGTF2A2
IDA
SceS000001541
ISS
AthAt4g24440
DmeFBgn0013347
SpoSPCC553.11c
GO:0006368 RNA elongation from RNA polymerase II
promoter
P
EXP
HsaGTF2A2
GO:0010552 positive regulation of gene-specific transcription
from RNA polymerase II promoter
P
IDA
HsaGTF2A2
GO:0032568 general transcription from RNA polymerase II
promoter
P
IDA
HsaGTF2A2
GO:0045449 regulation of transcription P
ISS
SpoSPCC553.11c
GO:0051091 positive regulation of transcription factor
activity
P
IDA
HsaGTF2A2
GO:0051123 RNA polymerase II transcriptional preinitiation
complex assembly
P
IDA
HsaGTF2A2

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2756

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga6915 ENSANGP00000013128
Ashbya gossypii (Ago) ago662 ABR071W
Arabidopsis thaliana (Ath) ath20408 At4g24440.1
Arabidopsis thaliana (Ath) ath20409 At4g24440.2
Caenorhabditis elegans (Cel) cel366 B0336.13
(CE26429;
WBGene00015150)
Caenorhabditis elegans (Cel) cel17644 Y111B2A.13
(CE26630;
WBGene00013736)
Candida glabrata (Cgl) cgl2756 CAGL0I05434g
Cryptococcus neoformans (Cne) cne4139 177.m02897
Dictyostelium discoideum (Ddi) ddi13362 DDB0216276
Debaryomyces hansenii (Dha) dha5829 DEHA0G02992g
Drosophila melanogaster (Dme) dme15990 CG11639-PA
(FBgn0040338)
Drosophila melanogaster (Dme) dme14086 CG5163-PA
(FBgn0013347)
Danio rerio (Dre) dre21399 ENSDARP00000009522
(zgc:110584)
Q503H9
Encephalitozoon cuniculi (Ecu) ecu45 19073966
Takifugu rubripes (Fru) fru7286 SINFRUP00000156012
Gallus gallus (Gga) gga3776 ENSGALP00000006007
(GTF2A2)
A1IIE5
Homo sapiens (Hsa) hsa10717 ENSP00000267869
Kluyveromyces lactis (Kla) kla1770 KLLA0C12815g
Mus musculus (Mmu) mmu27880 ENSMUSP00000040393
(MGI:1933289)
Q3UT44
Neurospora crassa (Ncr) ncr9492 NCU09748.2
Oryza sativa (Osa) osa10595 2781.m00173
Oryza sativa (Osa) osa15566 2996.m00149
Oryza sativa (Osa) osa24843 3832.m00151
Oryza sativa (Osa) osa48911 5723.m00198
Rattus norvegicus (Rno) rno28870 ENSRNOP00000014706
(RGD:620720)
O08950
Saccharomyces cerevisiae (Sce) sce3723 YKL058W
(S000001541)
Schizosaccharomyces pombe (Spo) spo2321 SPCC553.11c O74948
Yarrowia lipolytica (Yli) yli6278 YALI0F22136g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC553.11c
NAS
DmeFBgn0013347
FBgn0040338
GO:0005672 transcription factor TFIIA complex C
IDA
SceS000001541
ISS
AthAt4g24440
DmeFBgn0013347
FBgn0040338
SpoSPCC553.11c
GO:0005829 cytosol C
IDA
SpoSPCC553.11c
GO:0003702 RNA polymerase II transcription factor
activity
F
ISS
AthAt4g24440
GO:0016251 general RNA polymerase II transcription factor
activity
F
IDA
SceS000001541
ISS
DmeFBgn0013347
FBgn0040338
SpoSPCC553.11c
GO:0006357 regulation of transcription from RNA polymerase II
promoter
P
NAS
DmeFBgn0013347
FBgn0040338
GO:0006367 transcription initiation from RNA polymerase II
promoter
P
IDA
SceS000001541
ISS
AthAt4g24440
DmeFBgn0040338
FBgn0013347
SpoSPCC553.11c
GO:0045449 regulation of transcription P
ISS
SpoSPCC553.11c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC553.11c
(O74948)
YKL058W
(S000001541)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC553.11c
GO:0005672 transcription factor TFIIA complex C
IDA
SceS000001541
ISS
SpoSPCC553.11c
GO:0005829 cytosol C
IDA
SpoSPCC553.11c
GO:0016251 general RNA polymerase II transcription factor
activity
F
IDA
SceS000001541
ISS
SpoSPCC553.11c
GO:0006367 transcription initiation from RNA polymerase II
promoter
P
IDA
SceS000001541
ISS
SpoSPCC553.11c
GO:0045449 regulation of transcription P
ISS
SpoSPCC553.11c

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk