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Search term: YKL060C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name FBA1
SGD link S000001543
Alternative ID YKL060C
Description Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis; catalyzes conversion of fructose 1,6 bisphosphate to glyceraldehyde-3-P and dihydroxyacetone-P; locates to mitochondrial outer surface upon oxidative stress
Synonyms YKL060C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4153 A---YP-

KOGs classification KOGs description
METABOLISM Fructose 1,6-bisphosphate aldolase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g18270_2 GI:15221035
Saccharomyces cerevisiae (Sce) YKL060c
(S000001543)		 GI:6322790 P14540
Schizosaccharomyces pombe (Spo) SPBC19C2.07 GI:19112484 P36580


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
AthAt1g18270
SpoSPBC19C2.07
GO:0005737 cytoplasm C
IDA
SceS000001543
ISS
SpoSPBC19C2.07
GO:0005739 mitochondrion C
IDA
SceS000001543
GO:0005829 cytosol C
IDA
SceS000001543
SpoSPBC19C2.07
GO:0004332 fructose-bisphosphate aldolase
activity		 F
IDA
SceS000001543
IMP
SceS000001543
ISS
AthAt1g18270
SpoSPBC19C2.07
GO:0006094 gluconeogenesis P
IMP
SceS000001543
GO:0006096 glycolysis P
IMP
SceS000001543
ISS
AthAt1g18270
SpoSPBC19C2.07
GO:0006417 regulation of translation P
RCA
SceS000001543

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6360

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) fba1
(SPBC19C2.07)		 GI:19112484 P36580
Saccharomyces cerevisiae (Sce) FBA1
(S000001543)		 GI:6322790 P14540
Kluyveromyces lactis (Kla) KLLA0E07546g GI:50308575
Eremothecium gossypii (Ego) AGOS_ABR068C GI:45185297
Magnaporthe grisea (Mgr) MGG_00223 GI:145611652
Neurospora crassa (Ncr) NCU07807.1 GI:32416070


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC19C2.07
GO:0005737 cytoplasm C
IDA
SceS000001543
ISS
SpoSPBC19C2.07
GO:0005739 mitochondrion C
IDA
SceS000001543
GO:0005829 cytosol C
IDA
SceS000001543
SpoSPBC19C2.07
GO:0004332 fructose-bisphosphate aldolase
activity		 F
IDA
SceS000001543
IMP
SceS000001543
ISS
SpoSPBC19C2.07
GO:0006094 gluconeogenesis P
IMP
SceS000001543
GO:0006096 glycolysis P
IMP
SceS000001543
ISS
SpoSPBC19C2.07
GO:0006417 regulation of translation P
RCA
SceS000001543

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_8552

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago659 ABR068C
Candida glabrata (Cgl) cgl4183 CAGL0L02497g
Cryptococcus neoformans (Cne) cne4599 186.m03440
Debaryomyces hansenii (Dha) dha3163 DEHA0D19327g
Escherichia coli (Eco) eco2826 16130826
Kluyveromyces lactis (Kla) kla3289 KLLA0E07546g
Neurospora crassa (Ncr) ncr7603 NCU07807.2
Saccharomyces cerevisiae (Sce) sce3725 YKL060C
(S000001543)
Schizosaccharomyces pombe (Spo) spo4378 SPBC19C2.07 P36580
Yarrowia lipolytica (Yli) yli4931 YALI0E26004g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC19C2.07
GO:0005737 cytoplasm C
IDA
SceS000001543
ISS
SpoSPBC19C2.07
GO:0005739 mitochondrion C
IDA
SceS000001543
GO:0005829 cytosol C
IDA
SceS000001543
SpoSPBC19C2.07
GO:0004332 fructose-bisphosphate aldolase
activity		 F
IDA
SceS000001543
IMP
SceS000001543
ISS
SpoSPBC19C2.07
GO:0006094 gluconeogenesis P
IMP
SceS000001543
GO:0006096 glycolysis P
IMP
SceS000001543
ISS
SpoSPBC19C2.07
GO:0006417 regulation of translation P
RCA
SceS000001543

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC19C2.07
(P36580)		 YKL060C
(S000001543)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC19C2.07
GO:0005737 cytoplasm C
IDA
SceS000001543
ISS
SpoSPBC19C2.07
GO:0005739 mitochondrion C
IDA
SceS000001543
GO:0005829 cytosol C
IDA
SceS000001543
SpoSPBC19C2.07
GO:0004332 fructose-bisphosphate aldolase
activity		 F
IDA
SceS000001543
IMP
SceS000001543
ISS
SpoSPBC19C2.07
GO:0006094 gluconeogenesis P
IMP
SceS000001543
GO:0006096 glycolysis P
IMP
SceS000001543
ISS
SpoSPBC19C2.07
GO:0006417 regulation of translation P
RCA
SceS000001543

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GO info in one table:

s.khadayate@ucl.ac.uk