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Search term: YKL078W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DHR2
SGD link S000001561
Alternative ID YKL078W
Description Predominantly nucleolar DEAH-box ATP-dependent RNA helicase, required for 18S rRNA synthesis
Synonyms YKL078W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0922 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DEAH-box RNA helicase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g26370 GI:15222700
Arabidopsis thaliana (Ath) At1g27900 GI:12323006
Arabidopsis thaliana (Ath) At3g26560 GI:15231574
Arabidopsis thaliana (Ath) At4g01020_1 GI:7486358
Arabidopsis thaliana (Ath) At4g18470_2 GI:7486291
Arabidopsis thaliana (Ath) At5g10370_1 GI:15238144
Caenorhabditis elegans (Cel) CE01889
(WBGene00003393)		 GI:17535281 Q09530
Caenorhabditis elegans (Cel) CE13245 GI:17508875
Caenorhabditis elegans (Cel) CE27311
(WBGene00022056)		 GI:17556386 Q9BKQ8
Caenorhabditis elegans (Cel) CE27603 GI:17543090
Drosophila melanogaster (Dme) 7293584_2 GI:7293584
Drosophila melanogaster (Dme) 7295673 GI:7295673
Drosophila melanogaster (Dme) 7303231
(pea)		 GI:20129977
Homo sapiens (Hsa) Hs17442794 GI:17442794
Homo sapiens (Hsa) Hs20336302
(DHX33)		 GI:20336302 Q9NPV4
Homo sapiens (Hsa) Hs20544129
(DHX35)		 GI:20544129 Q9H5Z1
Homo sapiens (Hsa) Hs21361576 GI:7023499 Q9NP64
Homo sapiens (Hsa) Hs21362038 GI:18848216 Q8IX18
Homo sapiens (Hsa) Hs22066120 GI:22066120
Homo sapiens (Hsa) Hs4826690
(DHX8)		 GI:4826690 Q14562
Homo sapiens (Hsa) Hs7661934 GI:7661934
Homo sapiens (Hsa) HsM13375825 GI:13375825
Homo sapiens (Hsa) HsM7705533 GI:7705533
Saccharomyces cerevisiae (Sce) YER013w
(S000000815)		 GI:6320850 P24384
Saccharomyces cerevisiae (Sce) YKL078w
(S000001561)		 GI:6322772 P36009
Schizosaccharomyces pombe (Spo) SPAC10F6.02c GI:19114165 O42643
Schizosaccharomyces pombe (Spo) SPAC145.03 GI:19114541
Schizosaccharomyces pombe (Spo) SPAC2G11.11c GI:19114003 Q03319
Encephalitozoon cuniculi (Ecu) ECU04g0250 GI:19074102 Q8SS67
Encephalitozoon cuniculi (Ecu) ECU11g0860 GI:19074886 Q8SQW7
Arabidopsis thaliana (Ath) At1g26370 GI:15222700
Arabidopsis thaliana (Ath) At1g27900 GI:12323006
Arabidopsis thaliana (Ath) At3g26560 GI:15231574
Arabidopsis thaliana (Ath) At4g01020_1 GI:7486358
Arabidopsis thaliana (Ath) At4g18470_2 GI:7486291
Arabidopsis thaliana (Ath) At5g10370_1 GI:15238144
Caenorhabditis elegans (Cel) CE01889
(WBGene00003393)		 GI:17535281 Q09530
Caenorhabditis elegans (Cel) CE13245 GI:17508875
Caenorhabditis elegans (Cel) CE27311
(WBGene00022056)		 GI:17556386 Q9BKQ8
Caenorhabditis elegans (Cel) CE27603 GI:17543090
Drosophila melanogaster (Dme) 7293584_2 GI:7293584
Drosophila melanogaster (Dme) 7295673 GI:7295673
Drosophila melanogaster (Dme) 7303231
(pea)		 GI:20129977
Homo sapiens (Hsa) Hs17442794 GI:17442794
Homo sapiens (Hsa) Hs20336302
(DHX33)		 GI:20336302 Q9NPV4
Homo sapiens (Hsa) Hs20544129
(DHX35)		 GI:20544129 Q9H5Z1
Homo sapiens (Hsa) Hs21361576 GI:7023499 Q9NP64
Homo sapiens (Hsa) Hs21362038 GI:18848216 Q8IX18
Homo sapiens (Hsa) Hs22066120 GI:22066120
Homo sapiens (Hsa) Hs4826690
(DHX8)		 GI:4826690 Q14562
Homo sapiens (Hsa) Hs7661934 GI:7661934
Homo sapiens (Hsa) HsM13375825 GI:13375825
Homo sapiens (Hsa) HsM7705533 GI:7705533
Saccharomyces cerevisiae (Sce) YER013w
(S000000815)		 GI:6320850 P24384
Saccharomyces cerevisiae (Sce) YKL078w
(S000001561)		 GI:6322772 P36009
Schizosaccharomyces pombe (Spo) SPAC10F6.02c GI:19114165 O42643
Schizosaccharomyces pombe (Spo) SPAC145.03 GI:19114541
Schizosaccharomyces pombe (Spo) SPAC2G11.11c GI:19114003 Q03319
Encephalitozoon cuniculi (Ecu) ECU04g0250 GI:19074102 Q8SS67
Encephalitozoon cuniculi (Ecu) ECU11g0860 GI:19074886 Q8SQW7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g27900
GO:0005634 nucleus C
IC
Dmepea
IDA
AthAt4g18470
SpoSPAC10F6.02c
GO:0005681 spliceosomal complex C
ISS
Dmepea
SpoSPAC10F6.02c
GO:0005730 nucleolus C
IDA
SceS000001561
SpoSPAC2G11.11c
ISS
SpoSPAC2G11.11c
GO:0005739 mitochondrion C
IDA
AthAt3g26560
GO:0005829 cytosol C
IDA
AthAt3g26560
GO:0071007 U2-type catalytic step 2 spliceosome C
IMP
SceS000000815
GO:0071011 precatalytic spliceosome C
IDA
Dmepea
GO:0071013 catalytic step 2 spliceosome C
IDA
Dmepea
GO:0071021 U2-type post-spliceosomal complex C
IMP
SceS000000815
GO:0000386 second spliceosomal transesterification
activity		 F
IDA
SceS000000815
IMP
SceS000000815
GO:0003676 nucleic acid binding F
ISS
AthAt4g01020
At5g10370
GO:0003723 RNA binding F
ISS
AthAt3g26560
GO:0003724 RNA helicase activity F
IDA
SceS000001561
ISS
AthAt1g26370
GO:0004004 ATP-dependent RNA helicase activity F
IDA
SceS000000815
ISS
AthAt1g27900
At3g26560
Dmepea
SpoSPAC10F6.02c
SPAC2G11.11c
TAS
HsaDHX8
GO:0004386 helicase activity F
ISS
AthAt4g01020
At5g10370
GO:0005515 protein binding F
IPI
HsaDHX8
GO:0005524 ATP binding F
ISS
AthAt3g26560
At4g01020
At5g10370
SpoSPAC2G11.11c
GO:0016564 transcription repressor activity F
IDA
AthAt4g18470
GO:0000003 reproduction P
IMP
CelWBGene00003393
GO:0000350 generation of catalytic spliceosome for second
transesterification step		 P
IDA
SceS000000815
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome		 P
IMP
Dmepea
GO:0000390 spliceosome disassembly P
IMP
SceS000000815
ISS
SpoSPAC10F6.02c
GO:0000398 nuclear mRNA splicing, via spliceosome P
IC
Dmepea
ISS
Dmepea
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA
transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA)		 P
IMP
SceS000001561
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00003393
GO:0002119 nematode larval development P
IMP
CelWBGene00003393
GO:0006396 RNA processing P
TAS
HsaDHX8
GO:0007281 germ cell development P
IMP
CelWBGene00003393
GO:0007286 spermatid development P
IMP
Dmepea
GO:0008150 biological_process P
ND
AthAt1g26370
At1g27900
GO:0009627 systemic acquired resistance P
TAS
AthAt4g18470
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003393
GO:0010113 negative regulation of systemic acquired
resistance		 P
IMP
AthAt4g18470
GO:0010172 embryonic body morphogenesis P
IMP
CelWBGene00003393
GO:0016444 somatic cell DNA recombination P
IMP
AthAt4g18470
GO:0016570 histone modification P
IMP
AthAt4g18470
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00003393
GO:0040007 growth P
IMP
CelWBGene00003393
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003393
GO:0040011 locomotion P
IMP
CelWBGene00003393
GO:0040022 feminization of hermaphroditic
germ-line		 P
IMP
CelWBGene00003393
GO:0042254 ribosome biogenesis P
IDA
SceS000001561
ISS
SpoSPAC2G11.11c
TAS
SceS000001561
GO:0048589 developmental growth P
IMP
CelWBGene00003393

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74733

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) prh1
(SPAC2G11.11c)		 GI:19114003 Q03319
Saccharomyces cerevisiae (Sce) DHR2
(S000001561)		 GI:6322772 P36009
Kluyveromyces lactis (Kla) KLLA0F26224g GI:50312429
Eremothecium gossypii (Ego) AGOS_ADR140C GI:45188013
Magnaporthe grisea (Mgr) MGG_00523 GI:39974661
Neurospora crassa (Ncr) NCU09254.1 GI:32422405


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
IDA
SceS000001561
SpoSPAC2G11.11c
ISS
SpoSPAC2G11.11c
GO:0003724 RNA helicase activity F
IDA
SceS000001561
GO:0004004 ATP-dependent RNA helicase activity F
ISS
SpoSPAC2G11.11c
GO:0005524 ATP binding F
ISS
SpoSPAC2G11.11c
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA
transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA)		 P
IMP
SceS000001561
GO:0042254 ribosome biogenesis P
IDA
SceS000001561
ISS
SpoSPAC2G11.11c
TAS
SceS000001561

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_15273

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1881 ADR140C
Candida glabrata (Cgl) cgl1509 CAGL0F06523g
Debaryomyces hansenii (Dha) dha4234 DEHA0E22528g
Kluyveromyces lactis (Kla) kla5248 KLLA0F26224g
Neurospora crassa (Ncr) ncr9020 NCU09254.2
Saccharomyces cerevisiae (Sce) sce3744 YKL078W
(S000001561)
Schizosaccharomyces pombe (Spo) spo2563 SPAC2G11.11c Q03319
Yarrowia lipolytica (Yli) yli1234 YALI0B11968g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
IDA
SceS000001561
SpoSPAC2G11.11c
ISS
SpoSPAC2G11.11c
GO:0003724 RNA helicase activity F
IDA
SceS000001561
GO:0004004 ATP-dependent RNA helicase activity F
ISS
SpoSPAC2G11.11c
GO:0005524 ATP binding F
ISS
SpoSPAC2G11.11c
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA
transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA)		 P
IMP
SceS000001561
GO:0042254 ribosome biogenesis P
IDA
SceS000001561
ISS
SpoSPAC2G11.11c
TAS
SceS000001561

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC2G11.11c
(Q03319)		 YKL078W
(S000001561)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
IDA
SceS000001561
SpoSPAC2G11.11c
ISS
SpoSPAC2G11.11c
GO:0003724 RNA helicase activity F
IDA
SceS000001561
GO:0004004 ATP-dependent RNA helicase activity F
ISS
SpoSPAC2G11.11c
GO:0005524 ATP binding F
ISS
SpoSPAC2G11.11c
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA
transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA)		 P
IMP
SceS000001561
GO:0042254 ribosome biogenesis P
IDA
SceS000001561
ISS
SpoSPAC2G11.11c
TAS
SceS000001561

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