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Search term: YKL110C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name KTI12
SGD link S000001593
Alternative ID YKL110C
Description Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
Synonyms YKL110C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3062 A-DHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED RNA polymerase II elongator associated protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g13870 GI:15222972
Drosophila melanogaster (Dme) 7290238
(FBgn0023521)
GI:18543259
Homo sapiens (Hsa) Hs19923939
(KTI12)
GI:19923939 Q96EK9
Saccharomyces cerevisiae (Sce) YKL110c
(S000001593)
GI:6322739 P34253
Schizosaccharomyces pombe (Spo) SPAC30.02c GI:19115468 Q9P7V4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g13870
GO:0005634 nucleus C
IDA
SceS000001593
SpoSPAC30.02c
ISS
SpoSPAC30.02c
GO:0005737 cytoplasm C
IDA
SceS000001593
ISS
SpoSPAC30.02c
GO:0005829 cytosol C
IDA
SpoSPAC30.02c
GO:0003682 chromatin binding F
IDA
SceS000001593
ISS
SpoSPAC30.02c
GO:0005516 calmodulin binding F
IDA
AthAt1g13870
GO:0005524 ATP binding F
ISS
SpoSPAC30.02c
GO:0016887 ATPase activity F
ISS
SpoSPAC30.02c
GO:0017076 purine nucleotide binding F
ISS
AthAt1g13870
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000001593
GO:0006200 ATP catabolic process P
ISS
SpoSPAC30.02c
GO:0006357 regulation of transcription from RNA polymerase II
promoter
P
IGI
SceS000001593
GO:0006399 tRNA metabolic process P
RCA
SceS000001593
GO:0006400 tRNA modification P
ISS
SpoSPAC30.02c
GO:0009451 RNA modification P
RCA
SceS000001593
GO:0009933 meristem structural organization P
IMP
AthAt1g13870
GO:0016049 cell growth P
IPI
SceS000001593
GO:0048366 leaf development P
IMP
AthAt1g13870

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6347

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) KTI12 GI:19923939 Q96EK9
Pan troglodytes (Ptr) KTI12 GI:114556594
Mus musculus (Mmu) Kti12
(MGI:1923547)
GI:20270210 Q9D1R2
Rattus norvegicus (Rno) Kti12 GI:109475238
Gallus gallus (Gga) KTI12 GI:118094549
Drosophila melanogaster (Dme) CG3587
(FBgn0023521)
GI:18543259
Anopheles gambiae (Aga) AgaP_AGAP005190 GI:58385615
Caenorhabditis elegans (Cel) Y57G11C.43
(CE35120;
WBGene00013332)
GI:71999331
Schizosaccharomyces pombe (Spo) SPAC30.02c GI:19115468 Q9P7V4
Saccharomyces cerevisiae (Sce) KTI12
(S000001593)
GI:6322739 P34253
Kluyveromyces lactis (Kla) KLLA0F02926g GI:50310385
Eremothecium gossypii (Ego) AGOS_ABL049C GI:45185181
Magnaporthe grisea (Mgr) MGG_12920 GI:145602097
Neurospora crassa (Ncr) NCU00178.1 GI:32403302
Arabidopsis thaliana (Ath) DRL1 GI:15222972


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthDRL1
MmuMGI:1923547
GO:0005634 nucleus C
IDA
SceS000001593
SpoSPAC30.02c
ISS
SpoSPAC30.02c
GO:0005737 cytoplasm C
IDA
SceS000001593
ISS
SpoSPAC30.02c
GO:0005829 cytosol C
IDA
SpoSPAC30.02c
GO:0003674 molecular_function F
ND
MmuMGI:1923547
GO:0003682 chromatin binding F
IDA
SceS000001593
ISS
SpoSPAC30.02c
GO:0005516 calmodulin binding F
IDA
AthDRL1
GO:0005524 ATP binding F
ISS
SpoSPAC30.02c
GO:0016887 ATPase activity F
ISS
SpoSPAC30.02c
GO:0017076 purine nucleotide binding F
ISS
AthDRL1
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000001593
GO:0006200 ATP catabolic process P
ISS
SpoSPAC30.02c
GO:0006357 regulation of transcription from RNA polymerase II
promoter
P
IGI
SceS000001593
GO:0006399 tRNA metabolic process P
RCA
SceS000001593
GO:0006400 tRNA modification P
ISS
SpoSPAC30.02c
GO:0008150 biological_process P
ND
MmuMGI:1923547
GO:0009451 RNA modification P
RCA
SceS000001593
GO:0009555 pollen development P
IMP
AthDRL1
GO:0009933 meristem structural organization P
IMP
AthDRL1
GO:0016049 cell growth P
IPI
SceS000001593
GO:0048316 seed development P
IMP
AthDRL1
GO:0048366 leaf development P
IMP
AthDRL1

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_5045

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga577 ENSANGP00000010356
Ashbya gossypii (Ago) ago543 ABL049C
Arabidopsis thaliana (Ath) ath1460 At1g13870.1
Caenorhabditis elegans (Cel) cel20066 Y57G11C.43
(CE35120;
WBGene00013332)
Candida glabrata (Cgl) cgl3894 CAGL0K08646g
Cryptococcus neoformans (Cne) cne3612 176.m02346
Dictyostelium discoideum (Ddi) ddi2361 DDB0167251
Debaryomyces hansenii (Dha) dha748 DEHA0B01540g
Drosophila melanogaster (Dme) dme16151 CG3587-PA
(FBgn0023521)
Homo sapiens (Hsa) hsa1159 ENSP00000354474
Kluyveromyces lactis (Kla) kla4212 KLLA0F02926g
Neurospora crassa (Ncr) ncr171 NCU00178.2
Saccharomyces cerevisiae (Sce) sce3780 YKL110C
(S000001593)
Schizosaccharomyces pombe (Spo) spo1704 SPAC30.02c Q9P7V4
Yarrowia lipolytica (Yli) yli3930 YALI0E01738g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g13870
GO:0005634 nucleus C
IDA
SceS000001593
SpoSPAC30.02c
ISS
SpoSPAC30.02c
GO:0005737 cytoplasm C
IDA
SceS000001593
ISS
SpoSPAC30.02c
GO:0005829 cytosol C
IDA
SpoSPAC30.02c
GO:0003682 chromatin binding F
IDA
SceS000001593
ISS
SpoSPAC30.02c
GO:0005516 calmodulin binding F
IDA
AthAt1g13870
GO:0005524 ATP binding F
ISS
SpoSPAC30.02c
GO:0016887 ATPase activity F
ISS
SpoSPAC30.02c
GO:0017076 purine nucleotide binding F
ISS
AthAt1g13870
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000001593
GO:0006200 ATP catabolic process P
ISS
SpoSPAC30.02c
GO:0006357 regulation of transcription from RNA polymerase II
promoter
P
IGI
SceS000001593
GO:0006399 tRNA metabolic process P
RCA
SceS000001593
GO:0006400 tRNA modification P
ISS
SpoSPAC30.02c
GO:0009451 RNA modification P
RCA
SceS000001593
GO:0009933 meristem structural organization P
IMP
AthAt1g13870
GO:0016049 cell growth P
IPI
SceS000001593
GO:0048366 leaf development P
IMP
AthAt1g13870

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC30.02c
(Q9P7V4)
YKL110C
(S000001593)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001593
SpoSPAC30.02c
ISS
SpoSPAC30.02c
GO:0005737 cytoplasm C
IDA
SceS000001593
ISS
SpoSPAC30.02c
GO:0005829 cytosol C
IDA
SpoSPAC30.02c
GO:0003682 chromatin binding F
IDA
SceS000001593
ISS
SpoSPAC30.02c
GO:0005524 ATP binding F
ISS
SpoSPAC30.02c
GO:0016887 ATPase activity F
ISS
SpoSPAC30.02c
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000001593
GO:0006200 ATP catabolic process P
ISS
SpoSPAC30.02c
GO:0006357 regulation of transcription from RNA polymerase II
promoter
P
IGI
SceS000001593
GO:0006399 tRNA metabolic process P
RCA
SceS000001593
GO:0006400 tRNA modification P
ISS
SpoSPAC30.02c
GO:0009451 RNA modification P
RCA
SceS000001593
GO:0016049 cell growth P
IPI
SceS000001593

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GO info in one table:

s.khadayate@ucl.ac.uk