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Search term: YKL114C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name APN1
SGD link S000001597
Alternative ID YKL114C
Description Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine
Synonyms YKL114C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3997 -C--YPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Major apurinic/apyrimidinic endonuclease/3'-repair diesterase APN1

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE28953
(WBGene00000151)		 GI:17531193 Q10002
Saccharomyces cerevisiae (Sce) YKL114c
(S000001597)		 GI:6322735 P22936
Schizosaccharomyces pombe (Spo) SPCC622.17 GI:19075689 P50525
Encephalitozoon cuniculi (Ecu) ECU11g1550i GI:19074955 Q8SQT2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001597
SpoSPCC622.17
GO:0005737 cytoplasm C
IDA
SpoSPCC622.17
GO:0005739 mitochondrion C
IDA
SceS000001597
ISS
SpoSPCC622.17
GO:0005829 cytosol C
IDA
SpoSPCC622.17
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
SceS000001597
IMP
SceS000001597
ISS
SceS000001597
SpoSPCC622.17
GO:0008081 phosphoric diester hydrolase activity F
IDA
SceS000001597
GO:0008311 double-stranded DNA specific 3'-5'
exodeoxyribonuclease activity		 F
IDA
SceS000001597
IMP
SpoSPCC622.17
GO:0017005 3'-tyrosyl-DNA phosphodiesterase
activity		 F
IDA
SceS000001597
GO:0006281 DNA repair P
RCA
SceS000001597
GO:0006284 base-excision repair P
IDA
SceS000001597
ISS
SpoSPCC622.17
GO:0006974 response to DNA damage stimulus P
RCA
SceS000001597
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000151

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6345

Species Gene ID NCBI link UniProt link
Caenorhabditis elegans (Cel) apn-1
(CE28953;
WBGene00000151)		 GI:17531193 Q10002
Schizosaccharomyces pombe (Spo) apn1
(SPCC622.17)		 GI:63054441 P50525
Saccharomyces cerevisiae (Sce) APN1
(S000001597)		 GI:6322735 P22936
Kluyveromyces lactis (Kla) KLLA0C14256g GI:50305755
Eremothecium gossypii (Ego) AGOS_ABL054C GI:45185176
Magnaporthe grisea (Mgr) MGG_10609 GI:39970001
Neurospora crassa (Ncr) NCU10044.1 GI:32405100
Plasmodium falciparum (Pfa) PF13_0176 GI:124513402


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001597
SpoSPCC622.17
GO:0005737 cytoplasm C
IDA
SpoSPCC622.17
GO:0005739 mitochondrion C
IDA
SceS000001597
ISS
SpoSPCC622.17
GO:0005829 cytosol C
IDA
SpoSPCC622.17
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
SceS000001597
IMP
SceS000001597
ISS
SceS000001597
SpoSPCC622.17
GO:0008081 phosphoric diester hydrolase activity F
IDA
SceS000001597
GO:0008311 double-stranded DNA specific 3'-5'
exodeoxyribonuclease activity		 F
IDA
SceS000001597
IMP
SpoSPCC622.17
GO:0017005 3'-tyrosyl-DNA phosphodiesterase
activity		 F
IDA
SceS000001597
GO:0006281 DNA repair P
RCA
SceS000001597
GO:0006284 base-excision repair P
IDA
SceS000001597
ISS
SpoSPCC622.17
GO:0006974 response to DNA damage stimulus P
RCA
SceS000001597
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000151

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3009

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago538 ABL054C
Caenorhabditis elegans (Cel) cel14690 T05H10.2
(CE28953;
WBGene00000151)
Candida glabrata (Cgl) cgl4014 CAGL0K11528g
Dictyostelium discoideum (Ddi) ddi12222 DDB0206584
Debaryomyces hansenii (Dha) dha5052 DEHA0F15015g
Danio rerio (Dre) dre3334 ENSDARP00000023071
Escherichia coli (Eco) eco2091 16130097
Encephalitozoon cuniculi (Ecu) ecu1043 19074955
Takifugu rubripes (Fru) fru18941 SINFRUP00000160071
Kluyveromyces lactis (Kla) kla1837 KLLA0C14256g
Neurospora crassa (Ncr) ncr9779 NCU10044.2
Plasmodium falciparum (Pfa) pfa4363 PF13_0176
Saccharomyces cerevisiae (Sce) sce3784 YKL114C
(S000001597)
Schizosaccharomyces pombe (Spo) spo1240 SPCC622.17 P50525
Yarrowia lipolytica (Yli) yli2219 YALI0C12144g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001597
SpoSPCC622.17
GO:0005737 cytoplasm C
IDA
SpoSPCC622.17
GO:0005739 mitochondrion C
IDA
SceS000001597
ISS
SpoSPCC622.17
GO:0005829 cytosol C
IDA
SpoSPCC622.17
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
SceS000001597
IMP
SceS000001597
ISS
SceS000001597
SpoSPCC622.17
GO:0008081 phosphoric diester hydrolase activity F
IDA
SceS000001597
GO:0008311 double-stranded DNA specific 3'-5'
exodeoxyribonuclease activity		 F
IDA
SceS000001597
IMP
SpoSPCC622.17
GO:0017005 3'-tyrosyl-DNA phosphodiesterase
activity		 F
IDA
SceS000001597
GO:0006281 DNA repair P
RCA
SceS000001597
GO:0006284 base-excision repair P
IDA
SceS000001597
ISS
SpoSPCC622.17
GO:0006974 response to DNA damage stimulus P
RCA
SceS000001597
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000151

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC622.17
(P50525)		 YKL114C
(S000001597)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001597
SpoSPCC622.17
GO:0005737 cytoplasm C
IDA
SpoSPCC622.17
GO:0005739 mitochondrion C
IDA
SceS000001597
ISS
SpoSPCC622.17
GO:0005829 cytosol C
IDA
SpoSPCC622.17
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
SceS000001597
IMP
SceS000001597
ISS
SceS000001597
SpoSPCC622.17
GO:0008081 phosphoric diester hydrolase activity F
IDA
SceS000001597
GO:0008311 double-stranded DNA specific 3'-5'
exodeoxyribonuclease activity		 F
IDA
SceS000001597
IMP
SpoSPCC622.17
GO:0017005 3'-tyrosyl-DNA phosphodiesterase
activity		 F
IDA
SceS000001597
GO:0006281 DNA repair P
RCA
SceS000001597
GO:0006284 base-excision repair P
IDA
SceS000001597
ISS
SpoSPCC622.17
GO:0006974 response to DNA damage stimulus P
RCA
SceS000001597

Back to the top
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GO info in one table:

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