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Search term: YKL116C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PRR1
SGD link S000001599
Alternative ID YKL116C
Description Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor
Synonyms YKL116C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0586 -CDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED Serine/threonine protein kinase

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE04699 GI:17568629
Caenorhabditis elegans (Cel) CE18594 GI:17559692
Caenorhabditis elegans (Cel) CE23838
(WBGene00003916)
GI:17562784
Caenorhabditis elegans (Cel) CE24522 GI:17566126
Caenorhabditis elegans (Cel) CE27768 GI:1118007 Q9TW45
Drosophila melanogaster (Dme) 7290249 GI:20128911 Q9W532
Drosophila melanogaster (Dme) 7299437 GI:7299437 Q9VGQ0
Drosophila melanogaster (Dme) 7299438 GI:7299438
Drosophila melanogaster (Dme) 7302463 GI:20130155
Drosophila melanogaster (Dme) 7302464 GI:7302464
Drosophila melanogaster (Dme) 7302570 GI:7302570 Q4QQA7
Homo sapiens (Hsa) Hs13899225 GI:13899225
Homo sapiens (Hsa) Hs14770402 GI:14770402
Homo sapiens (Hsa) Hs17474143 GI:17474143
Homo sapiens (Hsa) Hs17475913 GI:17475913
Homo sapiens (Hsa) Hs18576402 GI:18576402
Homo sapiens (Hsa) Hs21361133 GI:5714636
Homo sapiens (Hsa) Hs22062450 GI:22062450
Homo sapiens (Hsa) Hs22063287 GI:22063287
Homo sapiens (Hsa) Hs8923922 GI:8923922
Homo sapiens (Hsa) Hs9845487 GI:9845487
Homo sapiens (Hsa) Hs9845489 GI:9845489
Homo sapiens (Hsa) HsM4505103 GI:4505103
Saccharomyces cerevisiae (Sce) YKL116c
(S000001599)
GI:6322733 P28708
Schizosaccharomyces pombe (Spo) SPBC337.04 GI:19112197 O74815
Encephalitozoon cuniculi (Ecu) ECU08g1480 GI:19173473 Q8SR98
Caenorhabditis elegans (Cel) CE04699 GI:17568629
Caenorhabditis elegans (Cel) CE18594 GI:17559692
Caenorhabditis elegans (Cel) CE23838
(WBGene00003916)
GI:17562784
Caenorhabditis elegans (Cel) CE24522 GI:17566126
Caenorhabditis elegans (Cel) CE27768 GI:1118007 Q9TW45
Drosophila melanogaster (Dme) 7290249 GI:20128911 Q9W532
Drosophila melanogaster (Dme) 7299437 GI:7299437 Q9VGQ0
Drosophila melanogaster (Dme) 7299438 GI:7299438
Drosophila melanogaster (Dme) 7302463 GI:20130155
Drosophila melanogaster (Dme) 7302464 GI:7302464
Drosophila melanogaster (Dme) 7302570 GI:7302570 Q4QQA7
Homo sapiens (Hsa) Hs13899225 GI:13899225
Homo sapiens (Hsa) Hs14770402 GI:14770402
Homo sapiens (Hsa) Hs17474143 GI:17474143
Homo sapiens (Hsa) Hs17475913 GI:17475913
Homo sapiens (Hsa) Hs18576402 GI:18576402
Homo sapiens (Hsa) Hs21361133 GI:5714636
Homo sapiens (Hsa) Hs22062450 GI:22062450
Homo sapiens (Hsa) Hs22063287 GI:22063287
Homo sapiens (Hsa) Hs8923922 GI:8923922
Homo sapiens (Hsa) Hs9845487 GI:9845487
Homo sapiens (Hsa) Hs9845489 GI:9845489
Homo sapiens (Hsa) HsM4505103 GI:4505103
Saccharomyces cerevisiae (Sce) YKL116c
(S000001599)
GI:6322733 P28708
Schizosaccharomyces pombe (Spo) SPBC337.04 GI:19112197 O74815
Encephalitozoon cuniculi (Ecu) ECU08g1480 GI:19173473 Q8SR98


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001599
GO:0005829 cytosol C
IDA
SpoSPBC337.04
GO:0005938 cell cortex C
IDA
CelWBGene00003916
GO:0016020 membrane C
IDA
CelWBGene00003916
GO:0004674 protein serine/threonine kinase
activity
F
ISS
CelWBGene00003916
SpoSPBC337.04
TAS
SpoSPBC337.04
GO:0004702 receptor signaling protein serine/threonine kinase
activity
F
IMP
SceS000001599
ISS
SceS000001599
GO:0005524 ATP binding F
ISS
SpoSPBC337.04
GO:0000003 reproduction P
IMP
CelWBGene00003916
GO:0006468 protein amino acid phosphorylation P
ISS
SpoSPBC337.04
GO:0007163 establishment or maintenance of cell
polarity
P
IMP
CelWBGene00003916
GO:0007165 signal transduction P
NAS
SpoSPBC337.04
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00003916
GO:0009880 embryonic pattern specification P
IGI
CelWBGene00003916
IMP
CelWBGene00003916
GO:0009949 polarity specification of anterior/posterior
axis
P
TAS
CelWBGene00003916
GO:0030010 establishment of cell polarity P
IMP
CelWBGene00003916
GO:0031138 negative regulation of conjugation with cellular
fusion
P
IGI
SceS000001599
IMP
SceS000001599
GO:0040025 vulval development P
IMP
CelWBGene00003916
GO:0040027 negative regulation of vulval development P
IMP
CelWBGene00003916
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003916
GO:0045167 asymmetric protein localization involved in cell
fate determination
P
IMP
CelWBGene00003916
GO:0046020 negative regulation of transcription from RNA
polymerase II promoter by pheromones
P
IGI
SceS000001599
IMP
SceS000001599

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
22016

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) PRR1
(S000001599)
GI:6322733 P28708
Kluyveromyces lactis (Kla) KLLA0C14278g GI:50305757
Eremothecium gossypii (Ego) AGOS_ABL055C GI:45185175


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001599
GO:0004702 receptor signaling protein serine/threonine kinase
activity
F
IMP
SceS000001599
ISS
SceS000001599
GO:0031138 negative regulation of conjugation with cellular
fusion
P
IGI
SceS000001599
IMP
SceS000001599
GO:0046020 negative regulation of transcription from RNA
polymerase II promoter by pheromones
P
IGI
SceS000001599
IMP
SceS000001599

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_17559

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago537 ABL055C
Candida glabrata (Cgl) cgl4015 CAGL0K11550g
Kluyveromyces lactis (Kla) kla1838 KLLA0C14278g
Neurospora crassa (Ncr) ncr4019 NCU04143.2
Saccharomyces cerevisiae (Sce) sce3786 YKL116C
(S000001599)
Schizosaccharomyces pombe (Spo) spo2042 SPBC337.04 O74815
Yarrowia lipolytica (Yli) yli3002 YALI0D07150g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001599
GO:0005829 cytosol C
IDA
SpoSPBC337.04
GO:0004674 protein serine/threonine kinase
activity
F
ISS
SpoSPBC337.04
TAS
SpoSPBC337.04
GO:0004702 receptor signaling protein serine/threonine kinase
activity
F
IMP
SceS000001599
ISS
SceS000001599
GO:0005524 ATP binding F
ISS
SpoSPBC337.04
GO:0006468 protein amino acid phosphorylation P
ISS
SpoSPBC337.04
GO:0007165 signal transduction P
NAS
SpoSPBC337.04
GO:0031138 negative regulation of conjugation with cellular
fusion
P
IGI
SceS000001599
IMP
SceS000001599
GO:0046020 negative regulation of transcription from RNA
polymerase II promoter by pheromones
P
IGI
SceS000001599
IMP
SceS000001599

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC337.04
(O74815)
YKL116C
(S000001599)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001599
GO:0005829 cytosol C
IDA
SpoSPBC337.04
GO:0004674 protein serine/threonine kinase
activity
F
ISS
SpoSPBC337.04
TAS
SpoSPBC337.04
GO:0004702 receptor signaling protein serine/threonine kinase
activity
F
IMP
SceS000001599
ISS
SceS000001599
GO:0005524 ATP binding F
ISS
SpoSPBC337.04
GO:0006468 protein amino acid phosphorylation P
ISS
SpoSPBC337.04
GO:0007165 signal transduction P
NAS
SpoSPBC337.04
GO:0031138 negative regulation of conjugation with cellular
fusion
P
IGI
SceS000001599
IMP
SceS000001599
GO:0046020 negative regulation of transcription from RNA
polymerase II promoter by pheromones
P
IGI
SceS000001599
IMP
SceS000001599

Back to the top
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GO info in one table:

s.khadayate@ucl.ac.uk