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Search term: YKL134C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name OCT1
SGD link S000001617
Alternative ID YKL134C
Description Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis
Synonyms YKL134C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2090 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Metalloendopeptidase family - mitochondrial intermediate peptidase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g51540 GI:15242116
Caenorhabditis elegans (Cel) CE28378 GI:17543988
Drosophila melanogaster (Dme) 7302217
(FBgn0033038)		 GI:20129717 A1Z6H6
Homo sapiens (Hsa) Hs17489073 GI:17489073
Homo sapiens (Hsa) Hs20543391 GI:20543391
Homo sapiens (Hsa) Hs20548472 GI:20548472
Homo sapiens (Hsa) Hs22053778_1 GI:22053778
Homo sapiens (Hsa) Hs5174567 GI:5174567
Saccharomyces cerevisiae (Sce) YKL134c
(S000001617)		 GI:6322715 P35999
Schizosaccharomyces pombe (Spo) SPAC1F3.10c GI:19113925 Q10415


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001617
SpoSPAC1F3.10c
IGI
SceS000001617
IMP
SceS000001617
ISS
DmeFBgn0033038
GO:0005759 mitochondrial matrix C
ISS
SpoSPAC1F3.10c
GO:0009507 chloroplast C
IDA
AthAt5g51540
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt5g51540
GO:0004222 metalloendopeptidase activity F
IDA
SceS000001617
IMP
SceS000001617
ISS
AthAt5g51540
DmeFBgn0033038
SpoSPAC1F3.10c
GO:0006508 proteolysis P
ISS
AthAt5g51540
SpoSPAC1F3.10c
GO:0006627 protein processing involved in protein targeting
to mitochondrion		 P
IMP
SceS000001617
ISS
SpoSPAC1F3.10c
GO:0006879 cellular iron ion homeostasis P
IGI
SceS000001617
IMP
SceS000001617
ISS
SpoSPAC1F3.10c
GO:0016485 protein processing P
ISS
DmeFBgn0033038

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4337

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MIPEP GI:156105687
Canis familiaris (Cfa) MIPEP GI:73993514
Mus musculus (Mmu) Mipep
(MGI:1917728)		 GI:28076953 A6H611
Rattus norvegicus (Rno) Mipep
(RGD:621680)		 GI:13591987
Gallus gallus (Gga) MIPEP GI:118085037
Drosophila melanogaster (Dme) CG7791
(FBgn0033038)		 GI:20129717 A1Z6H6
Anopheles gambiae (Aga) AgaP_AGAP007728 GI:158285109
Caenorhabditis elegans (Cel) Y67H2A.7
(CE32274;
WBGene00013464)		 GI:32565901
Schizosaccharomyces pombe (Spo) oct1
(SPAC1F3.10c)		 GI:19113925 Q10415
Saccharomyces cerevisiae (Sce) OCT1
(S000001617)		 GI:6322715 P35999
Kluyveromyces lactis (Kla) KLLA0B12397g GI:50304265
Eremothecium gossypii (Ego) AGOS_AFR198W GI:45198716
Magnaporthe grisea (Mgr) MGG_00487 GI:39974733
Neurospora crassa (Ncr) NCU02063.1 GI:32417550
Arabidopsis thaliana (Ath) AT5G51540 GI:79534875
Oryza sativa (Osa) Os06g0686500 GI:115469604
Plasmodium falciparum (Pfa) MAL13P1.184 GI:124513484


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1917728
SceS000001617
SpoSPAC1F3.10c
IGI
SceS000001617
IMP
SceS000001617
ISS
DmeFBgn0033038
GO:0005759 mitochondrial matrix C
ISS
SpoSPAC1F3.10c
GO:0009507 chloroplast C
IDA
AthAt5g51540
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt5g51540
GO:0003674 molecular_function F
ND
MmuMGI:1917728
GO:0004222 metalloendopeptidase activity F
IDA
SceS000001617
IMP
SceS000001617
ISS
AthAt5g51540
DmeFBgn0033038
SpoSPAC1F3.10c
GO:0006508 proteolysis P
ISS
AthAt5g51540
SpoSPAC1F3.10c
GO:0006627 protein processing involved in protein targeting
to mitochondrion		 P
IMP
SceS000001617
ISS
SpoSPAC1F3.10c
TAS
HsaMIPEP
GO:0006879 cellular iron ion homeostasis P
IGI
SceS000001617
IMP
SceS000001617
ISS
SpoSPAC1F3.10c
GO:0008150 biological_process P
ND
MmuMGI:1917728
GO:0016485 protein processing P
ISS
DmeFBgn0033038

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2033

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3163 ENSANGP00000020780
Ashbya gossypii (Ago) ago3390 AFR198W
Arabidopsis thaliana (Ath) ath27096 At5g51540.1
Caenorhabditis elegans (Cel) cel20391 Y67H2A.7
(CE32274;
WBGene00013464)
Candida glabrata (Cgl) cgl751 CAGL0D02112g
Cryptococcus neoformans (Cne) cne5467 179.m00319
Cryptococcus neoformans (Cne) cne4771 186.m03644
Debaryomyces hansenii (Dha) dha5946 DEHA0G05566g
Drosophila melanogaster (Dme) dme3397 CG7791-PA
(FBgn0033038)
Danio rerio (Dre) dre6253 ENSDARP00000007690
Danio rerio (Dre) dre6252 ENSDARP00000020033
Danio rerio (Dre) dre13968 ENSDARP00000035611
Takifugu rubripes (Fru) fru4352 SINFRUP00000157541
Takifugu rubripes (Fru) fru4350 SINFRUP00000167008
Takifugu rubripes (Fru) fru4351 SINFRUP00000167445
Gallus gallus (Gga) gga3166 ENSGALP00000027603
(MIPEP)
Homo sapiens (Hsa) hsa8572 ENSP00000028585
Kluyveromyces lactis (Kla) kla1080 KLLA0B12397g
Mus musculus (Mmu) mmu8324 ENSMUSP00000022571
(MGI:1917728)
Mus musculus (Mmu) mmu8323 ENSMUSP00000069840
(MGI:1917728)		 A6H611
Neurospora crassa (Ncr) ncr2005 NCU02063.2
Oryza sativa (Osa) osa3664 1975.m00219
Oryza sativa (Osa) osa20287 3407.m00214
Oryza sativa (Osa) osa36979 4968.m00164
Plasmodium falciparum (Pfa) pfa3927 MAL13P1.184
Rattus norvegicus (Rno) rno11501 ENSRNOP00000018845
(RGD:621680)		 Q01992
Saccharomyces cerevisiae (Sce) sce3804 YKL134C
(S000001617)
Schizosaccharomyces pombe (Spo) spo4557 SPAC1F3.10c Q10415
Yarrowia lipolytica (Yli) yli331 YALI0A09988g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1917728
SceS000001617
SpoSPAC1F3.10c
IGI
SceS000001617
IMP
SceS000001617
ISS
DmeFBgn0033038
GO:0005759 mitochondrial matrix C
ISS
SpoSPAC1F3.10c
GO:0009507 chloroplast C
IDA
AthAt5g51540
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt5g51540
GO:0003674 molecular_function F
ND
MmuMGI:1917728
GO:0004222 metalloendopeptidase activity F
IDA
SceS000001617
IMP
SceS000001617
ISS
AthAt5g51540
DmeFBgn0033038
SpoSPAC1F3.10c
GO:0006508 proteolysis P
ISS
AthAt5g51540
SpoSPAC1F3.10c
GO:0006627 protein processing involved in protein targeting
to mitochondrion		 P
IMP
SceS000001617
ISS
SpoSPAC1F3.10c
GO:0006879 cellular iron ion homeostasis P
IGI
SceS000001617
IMP
SceS000001617
ISS
SpoSPAC1F3.10c
GO:0008150 biological_process P
ND
MmuMGI:1917728
GO:0016485 protein processing P
ISS
DmeFBgn0033038

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1F3.10c
(Q10415)		 YKL134C
(S000001617)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001617
SpoSPAC1F3.10c
IGI
SceS000001617
IMP
SceS000001617
GO:0005759 mitochondrial matrix C
ISS
SpoSPAC1F3.10c
GO:0004222 metalloendopeptidase activity F
IDA
SceS000001617
IMP
SceS000001617
ISS
SpoSPAC1F3.10c
GO:0006508 proteolysis P
ISS
SpoSPAC1F3.10c
GO:0006627 protein processing involved in protein targeting
to mitochondrion		 P
IMP
SceS000001617
ISS
SpoSPAC1F3.10c
GO:0006879 cellular iron ion homeostasis P
IGI
SceS000001617
IMP
SceS000001617
ISS
SpoSPAC1F3.10c

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