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Search term: YKL139W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CTK1
SGD link S000001622
Alternative ID YKL139W
Description Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity
Synonyms YKL139W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0600 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Cdc2-related protein kinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g03740 GI:15218897
Arabidopsis thaliana (Ath) At1g09600 GI:15217565
Arabidopsis thaliana (Ath) At1g18670 GI:15221833
Arabidopsis thaliana (Ath) At1g33770 GI:15217643
Arabidopsis thaliana (Ath) At1g53050 GI:15219169
Arabidopsis thaliana (Ath) At1g54610 GI:15221868
Arabidopsis thaliana (Ath) At1g57700 GI:15223647
Arabidopsis thaliana (Ath) At1g71530 GI:15217521
Arabidopsis thaliana (Ath) At1g74330 GI:15221219
Arabidopsis thaliana (Ath) At3g05050 GI:15229881
Arabidopsis thaliana (Ath) At4g10010 GI:15234886
Arabidopsis thaliana (Ath) At4g22940 GI:15235867
Arabidopsis thaliana (Ath) At5g10270 GI:15238114
Arabidopsis thaliana (Ath) At5g39420 GI:15241743
Arabidopsis thaliana (Ath) At5g44290 GI:15241455
Arabidopsis thaliana (Ath) At5g50860 GI:15241289
Arabidopsis thaliana (Ath) At5g64960 GI:15238314
Caenorhabditis elegans (Cel) CE26422 GI:17551782
Drosophila melanogaster (Dme) 7296451 GI:7296451
Homo sapiens (Hsa) Hs7706549 GI:7706549
Homo sapiens (Hsa) Hs14110387 GI:14110387
Homo sapiens (Hsa) Hs14110390 GI:14110390
Saccharomyces cerevisiae (Sce) YKL139w
(S000001622)		 GI:6322710 Q03957
Saccharomyces cerevisiae (Sce) YPR161c
(S000006365)		 GI:6325419 P23293
Schizosaccharomyces pombe (Spo) SPAC2F3.15 GI:19115305 O14098
Schizosaccharomyces pombe (Spo) SPBC32H8.10 GI:19112408 Q96WV9
Encephalitozoon cuniculi (Ecu) ECU08g1790 GI:19173504 Q8SR90
Encephalitozoon cuniculi (Ecu) ECU11g0960 GI:19074896 Q8SQW2
Arabidopsis thaliana (Ath) At1g03740 GI:15218897
Arabidopsis thaliana (Ath) At1g09600 GI:15217565
Arabidopsis thaliana (Ath) At1g18670 GI:15221833
Arabidopsis thaliana (Ath) At1g33770 GI:15217643
Arabidopsis thaliana (Ath) At1g53050 GI:15219169
Arabidopsis thaliana (Ath) At1g54610 GI:15221868
Arabidopsis thaliana (Ath) At1g57700 GI:15223647
Arabidopsis thaliana (Ath) At1g71530 GI:15217521
Arabidopsis thaliana (Ath) At1g74330 GI:15221219
Arabidopsis thaliana (Ath) At3g05050 GI:15229881
Arabidopsis thaliana (Ath) At4g10010 GI:15234886
Arabidopsis thaliana (Ath) At4g22940 GI:15235867
Arabidopsis thaliana (Ath) At5g10270 GI:15238114
Arabidopsis thaliana (Ath) At5g39420 GI:15241743
Arabidopsis thaliana (Ath) At5g44290 GI:15241455
Arabidopsis thaliana (Ath) At5g50860 GI:15241289
Arabidopsis thaliana (Ath) At5g64960 GI:15238314
Caenorhabditis elegans (Cel) CE26422 GI:17551782
Drosophila melanogaster (Dme) 7296451 GI:7296451
Homo sapiens (Hsa) Hs7706549 GI:7706549
Homo sapiens (Hsa) Hs14110387 GI:14110387
Homo sapiens (Hsa) Hs14110390 GI:14110390
Saccharomyces cerevisiae (Sce) YKL139w
(S000001622)		 GI:6322710 Q03957
Saccharomyces cerevisiae (Sce) YPR161c
(S000006365)		 GI:6325419 P23293
Schizosaccharomyces pombe (Spo) SPAC2F3.15 GI:19115305 O14098
Schizosaccharomyces pombe (Spo) SPBC32H8.10 GI:19112408 Q96WV9
Encephalitozoon cuniculi (Ecu) ECU08g1790 GI:19173504 Q8SR90
Encephalitozoon cuniculi (Ecu) ECU11g0960 GI:19074896 Q8SQW2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000307 cyclin-dependent protein kinase holoenzyme
complex		 C
IPI
SceS000006365
GO:0005575 cellular_component C
ND
AthAt1g33770
At1g09600
At1g74330
At4g10010
GO:0005634 nucleus C
IDA
AthAt5g64960
SceS000001622
SpoSPAC2F3.15
SPBC32H8.10
IPI
SceS000006365
GO:0005654 nucleoplasm C
IDA
SceS000001622
GO:0005730 nucleolus C
IDA
SceS000001622
SpoSPAC2F3.15
GO:0005829 cytosol C
IDA
AthAt5g10270
At5g64960
GO:0005844 polysome C
IDA
SceS000001622
GO:0005886 plasma membrane C
IDA
AthAt5g50860
At1g54610
At1g57700
At1g53050
At1g18670
At5g44290
At3g05050
GO:0008024 positive transcription elongation factor complex
b		 C
NAS
SpoSPAC2F3.15
SPBC32H8.10
GO:0016604 nuclear body C
IDA
AthAt5g64960
GO:0032806 carboxy-terminal domain protein kinase
complex		 C
IPI
SceS000001622
SpoSPAC2F3.15
GO:0070693 P-TEFb-cap methyltransferase complex C
IDA
SpoSPBC32H8.10
GO:0004672 protein kinase activity F
ISS
AthAt1g74330
At5g50860
GO:0004693 cyclin-dependent protein kinase
activity		 F
IDA
SceS000001622
S000006365
SpoSPBC32H8.10
IPI
SceS000006365
TAS
SpoSPAC2F3.15
GO:0005515 protein binding F
IGI
SpoSPBC32H8.10
IPI
SpoSPAC2F3.15
SPBC32H8.10
GO:0005524 ATP binding F
ISS
AthAt1g74330
SpoSPBC32H8.10
GO:0008353 RNA polymerase II carboxy-terminal domain kinase
activity		 F
IDA
SpoSPAC2F3.15
SPBC32H8.10
GO:0016301 kinase activity F
IDA
AthAt5g64960
At5g10270
ISS
AthAt5g44290
At1g18670
At1g57700
At1g33770
At5g10270
At5g64960
At5g39420
At4g10010
At1g03740
At1g09600
At1g54610
At1g53050
At1g71530
At3g05050
At4g22940
GO:0006350 transcription P
IDA
SceS000006365
IMP
SceS000006365
IPI
SceS000006365
GO:0006360 transcription from RNA polymerase I
promoter		 P
IGI
SpoSPBC32H8.10
GO:0006397 mRNA processing P
IEP
AthAt5g64960
IMP
AthAt5g64960
GO:0006468 protein amino acid phosphorylation P
IDA
SceS000006365
SpoSPBC32H8.10
IMP
SceS000001622
IPI
SceS000006365
ISS
AthAt5g50860
At1g74330
SceS000001622
GO:0007049 cell cycle P
IDA
SpoSPBC32H8.10
GO:0009615 response to virus P
IEP
AthAt5g64960
At5g10270
GO:0009908 flower development P
IMP
AthAt5g64960
GO:0018105 peptidyl-serine phosphorylation P
IDA
SceS000001622
GO:0031031 positive regulation of septation initiation
signaling		 P
IGI
SpoSPAC2F3.15
GO:0031124 mRNA 3'-end processing P
IGI
SceS000001622
IMP
SceS000001622
GO:0031565 cytokinesis checkpoint P
IMP
SpoSPAC2F3.15
GO:0031566 contractile ring maintenance involved in cell
cycle cytokinesis		 P
IGI
SpoSPAC2F3.15
IMP
SpoSPAC2F3.15
GO:0032786 positive regulation of RNA elongation P
IDA
SceS000001622
GO:0045903 positive regulation of translational
fidelity		 P
IMP
SceS000001622
GO:0045943 positive regulation of transcription from RNA
polymerase I promoter		 P
IMP
SceS000001622
GO:0048366 leaf development P
IGI
AthAt5g64960
At5g10270
GO:0048440 carpel development P
IGI
AthAt5g64960
GO:0050792 regulation of viral reproduction P
IMP
AthAt5g64960
GO:0051571 positive regulation of histone H3-K4
methylation		 P
IMP
SceS000006365
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape		 P
IMP
SpoSPAC2F3.15
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IDA
SceS000006365
IMP
SceS000001622
S000006365
SpoSPAC2F3.15
SPBC32H8.10
IPI
SceS000006365
GO:0090039 regulation of gene-specific transcription
elongation from RNA polymerase II
promoter		 P
IMP
SpoSPBC32H8.10

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117855

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) lsk1
(SPAC2F3.15)		 GI:19115305 O14098
Saccharomyces cerevisiae (Sce) CTK1
(S000001622)		 GI:6322710 Q03957
Kluyveromyces lactis (Kla) KLLA0E12177g GI:50308983
Eremothecium gossypii (Ego) AGOS_AFR205C GI:45198723
Magnaporthe grisea (Mgr) MGG_07291 GI:39971951
Neurospora crassa (Ncr) NCU06685.1 GI:32412982


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001622
SpoSPAC2F3.15
GO:0005654 nucleoplasm C
IDA
SceS000001622
GO:0005730 nucleolus C
IDA
SceS000001622
SpoSPAC2F3.15
GO:0005844 polysome C
IDA
SceS000001622
GO:0008024 positive transcription elongation factor complex
b		 C
NAS
SpoSPAC2F3.15
GO:0032806 carboxy-terminal domain protein kinase
complex		 C
IPI
SceS000001622
SpoSPAC2F3.15
GO:0004693 cyclin-dependent protein kinase
activity		 F
IDA
SceS000001622
TAS
SpoSPAC2F3.15
GO:0005515 protein binding F
IPI
SpoSPAC2F3.15
GO:0008353 RNA polymerase II carboxy-terminal domain kinase
activity		 F
IDA
SpoSPAC2F3.15
GO:0006468 protein amino acid phosphorylation P
IMP
SceS000001622
ISS
SceS000001622
GO:0018105 peptidyl-serine phosphorylation P
IDA
SceS000001622
GO:0031031 positive regulation of septation initiation
signaling		 P
IGI
SpoSPAC2F3.15
GO:0031124 mRNA 3'-end processing P
IGI
SceS000001622
IMP
SceS000001622
GO:0031565 cytokinesis checkpoint P
IMP
SpoSPAC2F3.15
GO:0031566 contractile ring maintenance involved in cell
cycle cytokinesis		 P
IGI
SpoSPAC2F3.15
IMP
SpoSPAC2F3.15
GO:0032786 positive regulation of RNA elongation P
IDA
SceS000001622
GO:0045903 positive regulation of translational
fidelity		 P
IMP
SceS000001622
GO:0045943 positive regulation of transcription from RNA
polymerase I promoter		 P
IMP
SceS000001622
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape		 P
IMP
SpoSPAC2F3.15
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IMP
SceS000001622
SpoSPAC2F3.15

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1658

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga115 ENSANGP00000010689
Ashbya gossypii (Ago) ago3397 AFR205C
Arabidopsis thaliana (Ath) ath23228 At5g10270.1
Arabidopsis thaliana (Ath) ath28644 At5g64960.1
Caenorhabditis elegans (Cel) cel292 B0285.1
(CE31401;
WBGene00007135)
Candida glabrata (Cgl) cgl746 CAGL0D02002g
Cryptococcus neoformans (Cne) cne350 162.m02957
Dictyostelium discoideum (Ddi) ddi2162 DDB0217274
Dictyostelium discoideum (Ddi) ddi11756 DDB0229428
Debaryomyces hansenii (Dha) dha1750 DEHA0C07139g
Debaryomyces hansenii (Dha) dha5818 DEHA0G02750g
Drosophila melanogaster (Dme) dme10599 CG7597-PA
(FBgn0037093)
Drosophila melanogaster (Dme) dme10598 CG7597-PB
(FBgn0037093)
Danio rerio (Dre) dre16660 ENSDARP00000018869
Danio rerio (Dre) dre27348 ENSDARP00000033731
Takifugu rubripes (Fru) fru2640 SINFRUP00000140103
Takifugu rubripes (Fru) fru16355 SINFRUP00000161826
Gallus gallus (Gga) gga13828 ENSGALP00000002654
(CDK12)
Gallus gallus (Gga) gga10277 ENSGALP00000020098
Homo sapiens (Hsa) hsa28498 ENSP00000181839
(CDK13)		 Q14004-1
Homo sapiens (Hsa) hsa13568 ENSP00000300647
(CDK12)		 B4DYX4
Homo sapiens (Hsa) hsa28499 ENSP00000340557
(CDK13)		 Q14004-2
Kluyveromyces lactis (Kla) kla3496 KLLA0E12177g
Mus musculus (Mmu) mmu4711 ENSMUSP00000003203
(MGI:1098802)		 Q14AX6-2
Mus musculus (Mmu) mmu6544 ENSMUSP00000036013
(MGI:1916812)		 Q69ZA1-1
Neurospora crassa (Ncr) ncr6501 NCU06685.2
Oryza sativa (Osa) osa26693 3952.m00080
Oryza sativa (Osa) osa36094 4752.m00132
Rattus norvegicus (Rno) rno6011 ENSRNOP00000008256
(RGD:621111)		 Q3MJK5-1
Rattus norvegicus (Rno) rno13415 ENSRNOP00000018431
(RGD:1311226)
Rattus norvegicus (Rno) rno6012 ENSRNOP00000041437
Saccharomyces cerevisiae (Sce) sce3810 YKL139W
(S000001622)
Schizosaccharomyces pombe (Spo) spo1908 SPAC2F3.15 O14098
Yarrowia lipolytica (Yli) yli1680 YALI0B22528g
Yarrowia lipolytica (Yli) yli3666 YALI0D22935g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
DmeFBgn0037093
MmuMGI:1098802
GO:0005634 nucleus C
IDA
AthAt5g64960
SceS000001622
SpoSPAC2F3.15
GO:0005654 nucleoplasm C
IDA
SceS000001622
GO:0005730 nucleolus C
IDA
SceS000001622
SpoSPAC2F3.15
GO:0005829 cytosol C
IDA
AthAt5g10270
At5g64960
GO:0005844 polysome C
IDA
SceS000001622
GO:0008024 positive transcription elongation factor complex
b		 C
NAS
SpoSPAC2F3.15
GO:0016604 nuclear body C
IDA
AthAt5g64960
GO:0032806 carboxy-terminal domain protein kinase
complex		 C
IPI
SceS000001622
SpoSPAC2F3.15
GO:0003674 molecular_function F
ND
MmuMGI:1098802
GO:0004693 cyclin-dependent protein kinase
activity		 F
IDA
SceS000001622
ISS
DmeFBgn0037093
TAS
SpoSPAC2F3.15
GO:0005515 protein binding F
IPI
SpoSPAC2F3.15
GO:0008353 RNA polymerase II carboxy-terminal domain kinase
activity		 F
IDA
SpoSPAC2F3.15
ISS
DmeFBgn0037093
GO:0016301 kinase activity F
IDA
AthAt5g64960
At5g10270
ISS
AthAt5g10270
At5g64960
GO:0000003 reproduction P
IMP
CelWBGene00007135
GO:0002119 nematode larval development P
IMP
CelWBGene00007135
GO:0006397 mRNA processing P
IEP
AthAt5g64960
IMP
AthAt5g64960
GO:0006468 protein amino acid phosphorylation P
IMP
SceS000001622
ISS
DmeFBgn0037093
SceS000001622
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00007135
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0037093
GO:0008150 biological_process P
ND
MmuMGI:1098802
GO:0009615 response to virus P
IEP
AthAt5g64960
At5g10270
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00007135
GO:0009908 flower development P
IMP
AthAt5g64960
GO:0010171 body morphogenesis P
IMP
CelWBGene00007135
GO:0018105 peptidyl-serine phosphorylation P
IDA
SceS000001622
GO:0031031 positive regulation of septation initiation
signaling		 P
IGI
SpoSPAC2F3.15
GO:0031124 mRNA 3'-end processing P
IGI
SceS000001622
IMP
SceS000001622
GO:0031565 cytokinesis checkpoint P
IMP
SpoSPAC2F3.15
GO:0031566 contractile ring maintenance involved in cell
cycle cytokinesis		 P
IGI
SpoSPAC2F3.15
IMP
SpoSPAC2F3.15
GO:0032786 positive regulation of RNA elongation P
IDA
SceS000001622
GO:0040007 growth P
IMP
CelWBGene00007135
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007135
GO:0040011 locomotion P
IMP
CelWBGene00007135
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00007135
GO:0045903 positive regulation of translational
fidelity		 P
IMP
SceS000001622
GO:0045943 positive regulation of transcription from RNA
polymerase I promoter		 P
IMP
SceS000001622
GO:0048366 leaf development P
IGI
AthAt5g64960
At5g10270
GO:0048440 carpel development P
IGI
AthAt5g64960
GO:0050792 regulation of viral reproduction P
IMP
AthAt5g64960
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape		 P
IMP
SpoSPAC2F3.15
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IMP
SceS000001622
SpoSPAC2F3.15

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC2F3.15
(O14098)		 YKL139W
(S000001622)
SPAC1D4.06c
(P36615)		 YKL139W
(S000001622)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001622
SpoSPAC1D4.06c
SPAC2F3.15
GO:0005654 nucleoplasm C
IDA
SceS000001622
GO:0005730 nucleolus C
IDA
SceS000001622
SpoSPAC2F3.15
GO:0005829 cytosol C
IDA
SpoSPAC1D4.06c
GO:0005844 polysome C
IDA
SceS000001622
GO:0008024 positive transcription elongation factor complex
b		 C
NAS
SpoSPAC2F3.15
GO:0032806 carboxy-terminal domain protein kinase
complex		 C
IPI
SceS000001622
SpoSPAC2F3.15
GO:0004674 protein serine/threonine kinase
activity		 F
IDA
SpoSPAC1D4.06c
GO:0004693 cyclin-dependent protein kinase
activity		 F
IDA
SceS000001622
TAS
SpoSPAC2F3.15
GO:0005515 protein binding F
IPI
SpoSPAC2F3.15
GO:0005524 ATP binding F
ISS
SpoSPAC1D4.06c
GO:0008353 RNA polymerase II carboxy-terminal domain kinase
activity		 F
IDA
SpoSPAC2F3.15
GO:0019912 cyclin-dependent protein kinase activating kinase
activity		 F
IGI
SpoSPAC1D4.06c
GO:0006468 protein amino acid phosphorylation P
IMP
SceS000001622
ISS
SceS000001622
SpoSPAC1D4.06c
GO:0007165 signal transduction P
IC
SpoSPAC1D4.06c
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC1D4.06c
GO:0018105 peptidyl-serine phosphorylation P
IDA
SceS000001622
GO:0031031 positive regulation of septation initiation
signaling		 P
IGI
SpoSPAC2F3.15
GO:0031124 mRNA 3'-end processing P
IGI
SceS000001622
IMP
SceS000001622
GO:0031565 cytokinesis checkpoint P
IMP
SpoSPAC2F3.15
GO:0031566 contractile ring maintenance involved in cell
cycle cytokinesis		 P
IGI
SpoSPAC2F3.15
IMP
SpoSPAC2F3.15
GO:0032786 positive regulation of RNA elongation P
IDA
SceS000001622
GO:0042327 positive regulation of phosphorylation P
IGI
SpoSPAC1D4.06c
GO:0045903 positive regulation of translational
fidelity		 P
IMP
SceS000001622
ISS
SpoSPAC1D4.06c
GO:0045943 positive regulation of transcription from RNA
polymerase I promoter		 P
IMP
SceS000001622
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape		 P
IMP
SpoSPAC2F3.15
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IMP
SceS000001622
SpoSPAC2F3.15

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Query species:

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GO info in one table:

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