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Search term: YKL140W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TGL1
SGD link S000001623
Alternative ID YKL140W
Description Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes
Synonyms YKL140W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2624 ACDHYP-

KOGs classification KOGs description
METABOLISM Triglyceride lipase-cholesterol esterase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g18460 GI:15221773
Arabidopsis thaliana (Ath) At1g73920 GI:12325144
Arabidopsis thaliana (Ath) At2g15230 GI:15226073
Arabidopsis thaliana (Ath) At5g14180 GI:9757799
Arabidopsis thaliana (Ath) At5g14190 GI:15241336
Caenorhabditis elegans (Cel) CE05874
(WBGene00009773)
GI:17561046 Q20449
Caenorhabditis elegans (Cel) CE09169 GI:17539664
Caenorhabditis elegans (Cel) CE11708
(WBGene00019376)
GI:17562160 Q94252
Caenorhabditis elegans (Cel) CE18444
(WBGene00022642)
GI:17566764 O61866
Caenorhabditis elegans (Cel) CE18732
(WBGene00010062)
GI:17561400 Q93789
Caenorhabditis elegans (Cel) CE24406
(WBGene00013050)
GI:17565922 Q9U276
Caenorhabditis elegans (Cel) CE26551
(WBGene00021963)
GI:17566024 Q95XV1
Caenorhabditis elegans (Cel) CE28762
(WBGene00020016)
GI:17563144 O16956
Caenorhabditis elegans (Cel) CE29647 GI:17566762 O61866
Drosophila melanogaster (Dme) 7291761 GI:7291761
Drosophila melanogaster (Dme) 7295808 GI:7295808
Drosophila melanogaster (Dme) 7296316 GI:7296316
Drosophila melanogaster (Dme) 7297720
(Lip4)
GI:19921102
Drosophila melanogaster (Dme) 7297721 GI:7297721
Drosophila melanogaster (Dme) 7297722 GI:7297722 Q9VKT7
Drosophila melanogaster (Dme) 7297727 GI:7297727 Q9VKT2
Drosophila melanogaster (Dme) 7297730 GI:7297730
Drosophila melanogaster (Dme) 7297731 GI:7297731
Drosophila melanogaster (Dme) 7297734 GI:7297734
Drosophila melanogaster (Dme) 7297743
(FBgn0023496)
GI:17975516
Drosophila melanogaster (Dme) 7297744
(FBgn0024740)
GI:17864232 Q9VKR5
Drosophila melanogaster (Dme) 7299656 GI:7299656
Drosophila melanogaster (Dme) 7299657 GI:7299657
Drosophila melanogaster (Dme) 7299658 GI:7299658
Drosophila melanogaster (Dme) 7299659 GI:7299659
Drosophila melanogaster (Dme) 7299660 GI:7299660
Drosophila melanogaster (Dme) 7299754
(FBgn0023495)
GI:17137504
Drosophila melanogaster (Dme) 7301402 GI:7301402
Drosophila melanogaster (Dme) 7302156 GI:7302156
Drosophila melanogaster (Dme) 7303096 GI:7303096
Homo sapiens (Hsa) Hs4557721 GI:4557721
Homo sapiens (Hsa) Hs4758676
(LIPF)
GI:4758676 P07098
Homo sapiens (Hsa) Hs17489492 GI:17489492
Homo sapiens (Hsa) Hs17489494_2 GI:17489494
Homo sapiens (Hsa) Hs22055178 GI:22055178
Homo sapiens (Hsa) Hs22055273 GI:22055273
Homo sapiens (Hsa) Hs20547935 GI:20547935
Saccharomyces cerevisiae (Sce) YKL140w
(S000001623)
GI:6322709 P34163
Saccharomyces cerevisiae (Sce) YLL012w
(S000003935)
GI:6323017 Q07804
Saccharomyces cerevisiae (Sce) YLR020c
(S000004010)
GI:6323048 Q07950
Schizosaccharomyces pombe (Spo) SPBC14C8.15 GI:19112710 O60095
Schizosaccharomyces pombe (Spo) SPBC16A3.12c GI:19113569 P78898
Schizosaccharomyces pombe (Spo) SPCC1672.09 GI:19075380 O74430


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SpoSPBC16A3.12c
GO:0005575 cellular_component C
ND
AthAt1g73920
HsaLIPF
GO:0005615 extracellular space C
TAS
AthAt2g15230
GO:0005737 cytoplasm C
IDA
SpoSPBC14C8.15
SPBC16A3.12c
SPCC1672.09
GO:0005794 Golgi apparatus C
IDA
SpoSPBC14C8.15
GO:0005811 lipid particle C
IDA
SceS000001623
S000003935
GO:0005886 plasma membrane C
IDA
SceS000004010
GO:0016021 integral to membrane C
IDA
SceS000001623
S000003935
S000004010
GO:0003824 catalytic activity F
ISS
AthAt5g14180
GO:0004771 sterol esterase activity F
IDA
SceS000003935
S000001623
S000004010
IMP
SceS000004010
ISS
SpoSPBC14C8.15
SPBC16A3.12c
SPCC1672.09
GO:0004806 triglyceride lipase activity F
IDA
AthAt2g15230
ISS
DmeFBgn0024740
FBgn0023496
Lip4
FBgn0023495
NAS
DmeFBgn0023495
TAS
HsaLIPF
GO:0008289 lipid binding F
NAS
HsaLIPF
GO:0016298 lipase activity F
ISS
AthAt1g18460
At1g73920
SceS000001623
SpoSPBC14C8.15
SPBC16A3.12c
SPCC1672.09
NAS
DmeFBgn0023496
FBgn0023495
GO:0016787 hydrolase activity F
ISS
AthAt2g15230
GO:0000003 reproduction P
IMP
CelWBGene00013050
GO:0000032 cell wall mannoprotein biosynthetic
process
P
IMP
SceS000004010
GO:0006066 alcohol metabolic process P
RCA
SceS000003935
GO:0006629 lipid metabolic process P
ISS
SpoSPBC14C8.15
SPBC16A3.12c
SPCC1672.09
GO:0006641 triglyceride metabolic process P
NAS
HsaLIPF
GO:0016125 sterol metabolic process P
IMP
SceS000003935
S000004010
S000001623
ISS
SpoSPBC14C8.15
SPBC16A3.12c
SPCC1672.09
GO:0019915 lipid storage P
IMP
CelWBGene00022642
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00019376
GO:0044242 cellular lipid catabolic process P
ISS
SpoSPBC14C8.15
SPBC16A3.12c
SPCC1672.09
GO:0044255 cellular lipid metabolic process P
IMP
SceS000001623
GO:0045132 meiotic chromosome segregation P
IMP
CelWBGene00022642

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
37277

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) LIPA GI:51317399
Pan troglodytes (Ptr) LIPA GI:114631749
Canis familiaris (Cfa) LIPA GI:73996092
Mus musculus (Mmu) Lipa
(MGI:96789)
GI:61098110 Q3TEL5
Rattus norvegicus (Rno) Lipa GI:77917572
Gallus gallus (Gga) LIPA GI:118092810
Drosophila melanogaster (Dme) CG18301
(FBgn0032265)
GI:24583470
Drosophila melanogaster (Dme) Lip4 GI:19921102
Drosophila melanogaster (Dme) CG7329
(FBgn0032271)
GI:24583480
Drosophila melanogaster (Dme) CG31871
(FBgn0051871)
GI:24583491
Anopheles gambiae (Aga) AgaP_AGAP001652 GI:158301800
Caenorhabditis elegans (Cel) lipase GI:17561400 Q93789
Caenorhabditis elegans (Cel) F01G10.7
(CE40352;
WBGene00008510)
GI:133930915
Caenorhabditis elegans (Cel) lipase GI:17562160 Q94252
Caenorhabditis elegans (Cel) lipase GI:17566764 O61866
Caenorhabditis elegans (Cel) lipase GI:17563144 O16956
Caenorhabditis elegans (Cel) Y57E12B.3
(CE26551;
WBGene00021963)
GI:17566024 Q95XV1
Caenorhabditis elegans (Cel) lipase GI:17561046 Q20449
Schizosaccharomyces pombe (Spo) SPCC1672.09 GI:19075380 O74430
Saccharomyces cerevisiae (Sce) TGL1
(S000001623)
GI:6322709 P34163
Eremothecium gossypii (Ego) AGOS_AFR206C GI:45198724
Magnaporthe grisea (Mgr) MGG_02622 GI:145610252
Neurospora crassa (Ncr) NCU02148.1 GI:32417720
Arabidopsis thaliana (Ath) MPL1 GI:42567840
Oryza sativa (Osa) Os08g0529800 GI:115477451


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthMPL1
GO:0005737 cytoplasm C
IDA
SpoSPCC1672.09
GO:0005764 lysosome C
ISO
MmuMGI:96789
GO:0005811 lipid particle C
IDA
SceS000001623
GO:0009543 chloroplast thylakoid lumen C
IDA
AthMPL1
GO:0016021 integral to membrane C
IDA
SceS000001623
GO:0003674 molecular_function F
ND
AthMPL1
GO:0003700 transcription factor activity F
ISS
AthMPL1
GO:0003723 RNA binding F
ISS
AthMPL1
GO:0003824 catalytic activity F
ISS
AthMPL1
GO:0004437 inositol or phosphatidylinositol phosphatase
activity
F
ISS
AthMPL1
GO:0004771 sterol esterase activity F
IDA
HsaLIPA
SceS000001623
ISO
MmuMGI:96789
ISS
SpoSPCC1672.09
GO:0004806 triglyceride lipase activity F
ISS
DmeFBgn0051871
Lip4
FBgn0032271
GO:0008441 3'(2'),5'-bisphosphate nucleotidase
activity
F
ISS
AthMPL1
GO:0008934 inositol-1(or 4)-monophosphatase
activity
F
IDA
AthMPL1
GO:0016298 lipase activity F
IDA
HsaLIPA
ISO
MmuMGI:96789
ISS
SceS000001623
SpoSPCC1672.09
GO:0000902 cell morphogenesis P
IMP
MmuMGI:96789
GO:0001816 cytokine production P
IMP
MmuMGI:96789
GO:0006355 regulation of transcription, DNA-dependent P
ISS
AthMPL1
GO:0006629 lipid metabolic process P
ISS
SpoSPCC1672.09
GO:0006631 fatty acid metabolic process P
ISO
MmuMGI:96789
GO:0006790 sulfur metabolic process P
ISS
AthMPL1
GO:0006952 defense response P
ISS
AthMPL1
GO:0006954 inflammatory response P
IMP
MmuMGI:96789
GO:0008150 biological_process P
ND
AthMPL1
GO:0008283 cell proliferation P
IMP
MmuMGI:96789
GO:0016125 sterol metabolic process P
IMP
SceS000001623
ISO
MmuMGI:96789
ISS
SpoSPCC1672.09
GO:0023034 intracellular signaling pathway P
ISS
AthMPL1
GO:0030324 lung development P
IMP
MmuMGI:96789
GO:0044242 cellular lipid catabolic process P
ISS
SpoSPCC1672.09
GO:0044255 cellular lipid metabolic process P
IMP
SceS000001623
GO:0048771 tissue remodeling P
IMP
MmuMGI:96789
GO:0048873 homeostasis of number of cells within a
tissue
P
IMP
MmuMGI:96789

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