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Search term: YKL166C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TPK3
SGD link S000001649
Alternative ID YKL166C
Description cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase
Synonyms YKL166C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0616 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING cAMP-dependent protein kinase catalytic subunit (PKA)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g20040 GI:15225287
Caenorhabditis elegans (Cel) CE04603 GI:17567857
Caenorhabditis elegans (Cel) CE15473
(WBGene00002189)
GI:17508227 P21137
Caenorhabditis elegans (Cel) CE15475 GI:17508225 P21137
Caenorhabditis elegans (Cel) CE27166
(WBGene00018569)
GI:17567859 Q95ZT2
Drosophila melanogaster (Dme) 7297542 GI:17136902
Drosophila melanogaster (Dme) 7301971 GI:7301971
Drosophila melanogaster (Dme) 7301972 GI:17864122
Homo sapiens (Hsa) Hs10835065 GI:10835065 O43930
Homo sapiens (Hsa) Hs4826948
(PRKX)
GI:4826948 P51817
Homo sapiens (Hsa) Hs15619015
(PRKACG)
GI:15619015 P22612
Homo sapiens (Hsa) Hs4506055
(PRKACA)
GI:4506055 P17612
Homo sapiens (Hsa) Hs4506057 GI:4506057 P22694
Saccharomyces cerevisiae (Sce) YJL164c
(S000003700)
GI:6322297
Saccharomyces cerevisiae (Sce) YKL166c
(S000001649)
GI:6322682 P05986
Saccharomyces cerevisiae (Sce) YPL203w
(S000006124)
GI:6325053 P06245
Schizosaccharomyces pombe (Spo) SPBC106.10 GI:19111951 P40376
Encephalitozoon cuniculi (Ecu) ECU07g0520 GI:19074474 Q8SRK8
Arabidopsis thaliana (Ath) At2g20040 GI:15225287
Caenorhabditis elegans (Cel) CE04603 GI:17567857
Caenorhabditis elegans (Cel) CE15473
(WBGene00002189)
GI:17508227 P21137
Caenorhabditis elegans (Cel) CE15475 GI:17508225 P21137
Caenorhabditis elegans (Cel) CE27166
(WBGene00018569)
GI:17567859 Q95ZT2
Drosophila melanogaster (Dme) 7297542 GI:17136902
Drosophila melanogaster (Dme) 7301971 GI:7301971
Drosophila melanogaster (Dme) 7301972 GI:17864122
Homo sapiens (Hsa) Hs10835065 GI:10835065 O43930
Homo sapiens (Hsa) Hs4826948
(PRKX)
GI:4826948 P51817
Homo sapiens (Hsa) Hs15619015
(PRKACG)
GI:15619015 P22612
Homo sapiens (Hsa) Hs4506055
(PRKACA)
GI:4506055 P17612
Homo sapiens (Hsa) Hs4506057 GI:4506057 P22694
Saccharomyces cerevisiae (Sce) YJL164c
(S000003700)
GI:6322297
Saccharomyces cerevisiae (Sce) YKL166c
(S000001649)
GI:6322682 P05986
Saccharomyces cerevisiae (Sce) YPL203w
(S000006124)
GI:6325053 P06245
Schizosaccharomyces pombe (Spo) SPBC106.10 GI:19111951 P40376
Encephalitozoon cuniculi (Ecu) ECU07g0520 GI:19074474 Q8SRK8


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
HsaPRKACA
GO:0005634 nucleus C
IDA
SceS000003700
S000006124
S000001649
SpoSPBC106.10
GO:0005737 cytoplasm C
IDA
SceS000003700
S000001649
SpoSPBC106.10
GO:0005829 cytosol C
EXP
HsaPRKACG
PRKACA
IDA
SpoSPBC106.10
GO:0005952 cAMP-dependent protein kinase complex C
IDA
SceS000006124
S000003700
IGI
SceS000003700
S000006124
S000001649
IPI
SceS000003700
S000006124
NAS
HsaPRKACA
TAS
SpoSPBC106.10
GO:0004691 cAMP-dependent protein kinase activity F
IDA
SceS000003700
S000006124
S000001649
IGI
SceS000003700
S000006124
S000001649
SpoSPBC106.10
IMP
SceS000003700
S000001649
ISS
SceS000006124
NAS
HsaPRKACA
TAS
HsaPRKX
GO:0004857 enzyme inhibitor activity F
RCA
SceS000001649
GO:0004862 cAMP-dependent protein kinase inhibitor
activity
F
EXP
HsaPRKACA
GO:0005515 protein binding F
IPI
HsaPRKACA
SpoSPBC106.10
GO:0005524 ATP binding F
ISS
SpoSPBC106.10
NAS
HsaPRKACA
GO:0019901 protein kinase binding F
IPI
HsaPRKACA
GO:0030234 enzyme regulator activity F
RCA
SceS000001649
GO:0001300 chronological cell aging P
IGI
SpoSPBC106.10
GO:0001315 age-dependent response to reactive oxygen
species
P
IGI
SpoSPBC106.10
IMP
SpoSPBC106.10
GO:0001403 invasive growth in response to glucose
limitation
P
IMP
SceS000006124
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00002189
GO:0002119 nematode larval development P
IMP
CelWBGene00002189
GO:0006110 regulation of glycolysis P
NAS
SpoSPBC106.10
GO:0006112 energy reserve metabolic process P
RCA
SceS000003700
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPBC106.10
IDA
SceS000003700
S000006124
S000001649
IMP
SceS000003700
S000001649
NAS
HsaPRKACA
GO:0006914 autophagy P
RCA
SceS000003700
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPBC106.10
GO:0007005 mitochondrion organization P
IGI
SceS000001649
IMP
SceS000001649
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000003700
GO:0007124 pseudohyphal growth P
RCA
SceS000006124
GO:0007243 intracellular protein kinase cascade P
EXP
HsaPRKACA
PRKACG
GO:0007265 Ras protein signal transduction P
IGI
SceS000003700
S000001649
S000006124
IMP
SceS000003700
ISS
SceS000006124
S000001649
GO:0007283 spermatogenesis P
TAS
HsaPRKACG
GO:0007568 aging P
RCA
SceS000006124
S000003700
GO:0008584 male gonad development P
TAS
HsaPRKACG
GO:0009755 hormone-mediated signaling pathway P
EXP
HsaPRKACA
PRKACG
GO:0016049 cell growth P
RCA
SceS000006124
GO:0018991 oviposition P
IMP
CelWBGene00002189
GO:0019933 cAMP-mediated signaling P
IC
SpoSPBC106.10
GO:0030435 sporulation resulting in formation of a cellular
spore
P
RCA
SceS000003700
GO:0031138 negative regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC106.10
GO:0031142 induction of conjugation upon nitrogen
starvation
P
IMP
SpoSPBC106.10
GO:0034199 activation of protein kinase A
activity
P
EXP
HsaPRKACA
PRKACG
GO:0045014 negative regulation of transcription by
glucose
P
IMP
SpoSPBC106.10
GO:0050790 regulation of catalytic activity P
RCA
SceS000003700
S000006124
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape
P
IMP
SpoSPBC106.10

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
55868

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PRKX GI:4826948 P51817
Pan troglodytes (Ptr) PRKX GI:114691904
Canis familiaris (Cfa) PRKX GI:74007085
Mus musculus (Mmu) Prkx
(MGI:1309999)
GI:23956080 Q3UDT1
Rattus norvegicus (Rno) Prkx
(RGD:1564076)
GI:77020270
Gallus gallus (Gga) PRKX GI:118084212
Drosophila melanogaster (Dme) Pka-C3
(FBgn0000489)
GI:24664872
Anopheles gambiae (Aga) AgaP_AGAP011840 GI:118793092
Caenorhabditis elegans (Cel) F47F2.1
(CE27166;
WBGene00018569)
GI:71990759
Saccharomyces cerevisiae (Sce) TPK3
(S000001649)
GI:6322682 P05986
Kluyveromyces lactis (Kla) KLLA0B07205g GI:50303809
Eremothecium gossypii (Ego) AGOS_AEL115C GI:45190492


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001649
GO:0005737 cytoplasm C
IDA
SceS000001649
GO:0005952 cAMP-dependent protein kinase complex C
IGI
SceS000001649
ISS
DmeFBgn0000489
GO:0004674 protein serine/threonine kinase
activity
F
ISS
MmuMGI:1309999
NAS
DmeFBgn0000489
GO:0004691 cAMP-dependent protein kinase activity F
IDA
DmeFBgn0000489
SceS000001649
IGI
SceS000001649
IMP
SceS000001649
ISS
DmeFBgn0000489
NAS
DmeFBgn0000489
TAS
HsaPRKX
GO:0004857 enzyme inhibitor activity F
RCA
SceS000001649
GO:0030234 enzyme regulator activity F
RCA
SceS000001649
GO:0006468 protein amino acid phosphorylation P
IDA
DmeFBgn0000489
SceS000001649
IMP
SceS000001649
ISS
DmeFBgn0000489
NAS
DmeFBgn0000489
GO:0007005 mitochondrion organization P
IGI
SceS000001649
IMP
SceS000001649
GO:0007265 Ras protein signal transduction P
IGI
SceS000001649
ISS
SceS000001649
GO:0007476 imaginal disc-derived wing morphogenesis P
IMP
DmeFBgn0000489
GO:0016310 phosphorylation P
ISS
MmuMGI:1309999

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_312

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga3466 ENSANGP00000016916
Anopheles gambiae (Aga) aga8995 ENSANGP00000020143
Ashbya gossypii (Ago) ago2391 AEL115C
Ashbya gossypii (Ago) ago3103 AFL090W
Caenorhabditis elegans (Cel) cel9530 F47F2.1b
(CE37114)
Caenorhabditis elegans (Cel) cel9531 F47F2.1c
(CE31171)
Caenorhabditis elegans (Cel) cel22350 ZK909.2a
(CE15473;
WBGene00002189)
Caenorhabditis elegans (Cel) cel22351 ZK909.2b
(CE15475)
Caenorhabditis elegans (Cel) cel22353 ZK909.2d
(CE31756)
Caenorhabditis elegans (Cel) cel22354 ZK909.2e
(CE31757)
Caenorhabditis elegans (Cel) cel22355 ZK909.2f
(CE31758)
Caenorhabditis elegans (Cel) cel22356 ZK909.2g
(CE31759)
Caenorhabditis elegans (Cel) cel22357 ZK909.2h
(CE31760)
Caenorhabditis elegans (Cel) cel22358 ZK909.2i
(CE31761)
Caenorhabditis elegans (Cel) cel22359 ZK909.2j
(CE31762)
Caenorhabditis elegans (Cel) cel22360 ZK909.2k
(CE31763)
Caenorhabditis elegans (Cel) cel22361 ZK909.2l
(CE31764)
Caenorhabditis elegans (Cel) cel22362 ZK909.2m
(CE31765)
Candida glabrata (Cgl) cgl2014 CAGL0G09020g
Candida glabrata (Cgl) cgl5021 CAGL0M08404g
Cryptococcus neoformans (Cne) cne309 162.m02868
Cryptococcus neoformans (Cne) cne2574 181.m08765
Dictyostelium discoideum (Ddi) ddi11974 DDB0185224
Dictyostelium discoideum (Ddi) ddi12610 DDB0215408
Dictyostelium discoideum (Ddi)