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Search term: YKL173W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SNU114
SGD link S000001656
Alternative ID YKL173W
Description GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2
Synonyms YKL173W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0468 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING U5 snRNP-specific protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g06220 GI:15221423
Arabidopsis thaliana (Ath) At5g25230 GI:15238745
Caenorhabditis elegans (Cel) CE05066
(WBGene00001166)		 GI:17552882 Q23463
Drosophila melanogaster (Dme) 7301652 GI:7301652
Homo sapiens (Hsa) Hs4759280 GI:4759280
Saccharomyces cerevisiae (Sce) YKL173w
(S000001656)		 GI:6322675 P36048
Schizosaccharomyces pombe (Spo) SPBC215.12 GI:19113481 O94316
Encephalitozoon cuniculi (Ecu) ECU09g0810 GI:19173203
Arabidopsis thaliana (Ath) At1g06220 GI:15221423
Arabidopsis thaliana (Ath) At5g25230 GI:15238745
Caenorhabditis elegans (Cel) CE05066
(WBGene00001166)		 GI:17552882 Q23463
Drosophila melanogaster (Dme) 7301652 GI:7301652
Homo sapiens (Hsa) Hs4759280 GI:4759280
Saccharomyces cerevisiae (Sce) YKL173w
(S000001656)		 GI:6322675 P36048
Schizosaccharomyces pombe (Spo) SPBC215.12 GI:19113481 O94316
Encephalitozoon cuniculi (Ecu) ECU09g0810 GI:19173203
Arabidopsis thaliana (Ath) At1g06220 GI:15221423
Arabidopsis thaliana (Ath) At5g25230 GI:15238745
Caenorhabditis elegans (Cel) CE05066
(WBGene00001166)		 GI:17552882 Q23463
Drosophila melanogaster (Dme) 7301652 GI:7301652
Homo sapiens (Hsa) Hs4759280 GI:4759280
Saccharomyces cerevisiae (Sce) YKL173w
(S000001656)		 GI:6322675 P36048
Schizosaccharomyces pombe (Spo) SPBC215.12 GI:19113481 O94316
Encephalitozoon cuniculi (Ecu) ECU09g0810 GI:19173203


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt1g06220
GO:0005634 nucleus C
IDA
SpoSPBC215.12
GO:0005681 spliceosomal complex C
IDA
SpoSPBC215.12
RCA
SceS000001656
GO:0005682 U5 snRNP C
IDA
SceS000001656
GO:0005730 nucleolus C
IDA
AthAt5g25230
GO:0005829 cytosol C
IDA
SpoSPBC215.12
GO:0005886 plasma membrane C
IDA
AthAt1g06220
GO:0016607 nuclear speck C
IDA
AthAt1g06220
GO:0046540 U4/U6 x U5 tri-snRNP complex C
IDA
SceS000001656
ISS
SpoSPBC215.12
GO:0003746 translation elongation factor activity F
ISS
AthAt5g25230
At1g06220
GO:0003924 GTPase activity F
IMP
SceS000001656
ISS
SceS000001656
SpoSPBC215.12
GO:0005525 GTP binding F
ISS
SceS000001656
SpoSPBC215.12
GO:0008135 translation factor activity, nucleic acid
binding		 F
ISS
AthAt1g06220
At5g25230
GO:0030623 U5 snRNA binding F
IDA
SceS000001656
GO:0045182 translation regulator activity F
RCA
SceS000001656
GO:0000003 reproduction P
IMP
CelWBGene00001166
GO:0000244 assembly of spliceosomal tri-snRNP P
IMP
SceS000001656
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IGI
SceS000001656
GO:0000388 spliceosome conformational change to release U4
(or U4atac) and U1 (or U11)		 P
IMP
SceS000001656
GO:0000398 nuclear mRNA splicing, via spliceosome P
IC
SpoSPBC215.12
IMP
SceS000001656
GO:0000910 cytokinesis P
IMP
CelWBGene00001166
GO:0002119 nematode larval development P
IMP
CelWBGene00001166
GO:0006184 GTP catabolic process P
ISS
SpoSPBC215.12
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001166
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt1g06220
GO:0016071 mRNA metabolic process P
RCA
SceS000001656
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00001166
GO:0040007 growth P
IMP
CelWBGene00001166
GO:0040011 locomotion P
IMP
CelWBGene00001166
GO:0045694 regulation of embryo sac egg cell
differentiation		 P
IMP
AthAt1g06220
GO:0051301 cell division P
IMP
CelWBGene00001166

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68800

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SNU114
(S000001656)		 GI:6322675 P36048
Kluyveromyces lactis (Kla) KLLA0A06688g GI:50302723
Eremothecium gossypii (Ego) AGOS_AEL124W GI:45190483


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005681 spliceosomal complex C
RCA
SceS000001656
GO:0005682 U5 snRNP C
IDA
SceS000001656
GO:0046540 U4/U6 x U5 tri-snRNP complex C
IDA
SceS000001656
GO:0003924 GTPase activity F
IMP
SceS000001656
ISS
SceS000001656
GO:0005525 GTP binding F
ISS
SceS000001656
GO:0030623 U5 snRNA binding F
IDA
SceS000001656
GO:0045182 translation regulator activity F
RCA
SceS000001656
GO:0000244 assembly of spliceosomal tri-snRNP P
IMP
SceS000001656
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IGI
SceS000001656
GO:0000388 spliceosome conformational change to release U4
(or U4atac) and U1 (or U11)		 P
IMP
SceS000001656
GO:0000398 nuclear mRNA splicing, via spliceosome P
IMP
SceS000001656
GO:0016071 mRNA metabolic process P
RCA
SceS000001656

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2005

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8805 ENSANGP00000017855
Ashbya gossypii (Ago) ago2382 AEL124W
Arabidopsis thaliana (Ath) ath593 At1g06220.1
Arabidopsis thaliana (Ath) ath594 At1g06220.2
Arabidopsis thaliana (Ath) ath24791 At5g25230.1
Caenorhabditis elegans (Cel) cel21814 ZK328.2
(CE05066;
WBGene00001166)
Candida glabrata (Cgl) cgl5016 CAGL0M08294g
Cryptococcus neoformans (Cne) cne635 163.m06161
Dictyostelium discoideum (Ddi) ddi5640 DDB0185466
Debaryomyces hansenii (Dha) dha4784 DEHA0F09053g
Drosophila melanogaster (Dme) dme14849 CG4849-PA
(FBgn0039566)
Takifugu rubripes (Fru) fru17893 SINFRUP00000135250
Takifugu rubripes (Fru) fru17894 SINFRUP00000174590
Gallus gallus (Gga) gga13762 ENSGALP00000001456
(EFTUD2)
Gallus gallus (Gga) gga13763 ENSGALP00000001457
Gallus gallus (Gga) gga13764 ENSGALP00000001458
Homo sapiens (Hsa) hsa13829 ENSP00000262414
(EFTUD2)		 Q15029
Kluyveromyces lactis (Kla) kla295 KLLA0A06688g
Mus musculus (Mmu) mmu4927 ENSMUSP00000021306
(MGI:1336880)		 A2AH85
Neurospora crassa (Ncr) ncr2492 NCU02572.2
Oryza sativa (Osa) osa20371 3409.m00116
Plasmodium falciparum (Pfa) pfa263 PF10_0041
Rattus norvegicus (Rno) rno6230 ENSRNOP00000003807
Saccharomyces cerevisiae (Sce) sce3847 YKL173W
(S000001656)
Schizosaccharomyces pombe (Spo) spo4305 SPBC215.12 O94316
Yarrowia lipolytica (Yli) yli718 YALI0A20768g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF10_0041
GO:0005618 cell wall C
IDA
AthAt1g06220
GO:0005634 nucleus C
IDA
MmuMGI:1336880
SpoSPBC215.12
GO:0005681 spliceosomal complex C
IDA
SpoSPBC215.12
RCA
SceS000001656
GO:0005682 U5 snRNP C
IDA
SceS000001656
ISS
DmeFBgn0039566
GO:0005730 nucleolus C
IDA
AthAt5g25230
GO:0005829 cytosol C
IDA
SpoSPBC215.12
ISS
DmeFBgn0039566
GO:0005886 plasma membrane C
IDA
AthAt1g06220
GO:0016607 nuclear speck C
IDA
AthAt1g06220
GO:0030532 small nuclear ribonucleoprotein
complex		 C
ISS
DmeFBgn0039566
GO:0046540 U4/U6 x U5 tri-snRNP complex C
IDA
SceS000001656
ISS
SpoSPBC215.12
GO:0071011 precatalytic spliceosome C
IDA
DmeFBgn0039566
GO:0071013 catalytic step 2 spliceosome C
IDA
DmeFBgn0039566
GO:0003746 translation elongation factor activity F
ISS
AthAt5g25230
At1g06220
DmeFBgn0039566
GO:0003924 GTPase activity F
IMP
SceS000001656
ISS
PfaPF10_0041
SceS000001656
SpoSPBC215.12
GO:0005515 protein binding F
IPI
MmuMGI:1336880
GO:0005525 GTP binding F
ISS
SceS000001656
SpoSPBC215.12
GO:0008135 translation factor activity, nucleic acid
binding		 F
ISS
AthAt1g06220
At5g25230
GO:0030623 U5 snRNA binding F
IDA
SceS000001656
GO:0045182 translation regulator activity F
RCA
SceS000001656
GO:0000003 reproduction P
IMP
CelWBGene00001166
GO:0000244 assembly of spliceosomal tri-snRNP P
IMP
SceS000001656
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IGI
SceS000001656
GO:0000388 spliceosome conformational change to release U4
(or U4atac) and U1 (or U11)		 P
IMP
SceS000001656
GO:0000398 nuclear mRNA splicing, via spliceosome P
IC
DmeFBgn0039566
SpoSPBC215.12
IMP
SceS000001656
ISS
DmeFBgn0039566
PfaPF10_0041
GO:0000910 cytokinesis P
IMP
CelWBGene00001166
GO:0002119 nematode larval development P
IMP
CelWBGene00001166
GO:0006184 GTP catabolic process P
ISS
SpoSPBC215.12
GO:0006414 translational elongation P
ISS
DmeFBgn0039566
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001166
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt1g06220
GO:0016071 mRNA metabolic process P
RCA
SceS000001656
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00001166
GO:0040007 growth P
IMP
CelWBGene00001166
GO:0040011 locomotion P
IMP
CelWBGene00001166
GO:0045694 regulation of embryo sac egg cell
differentiation		 P
IMP
AthAt1g06220
GO:0051301 cell division P
IMP
CelWBGene00001166

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC215.12
(O94316)		 YKL173W
(S000001656)