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Search term: YKL182W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name FAS1
SGD link S000001665
Alternative ID YKL182W
Description Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
Synonyms YKL182W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6326

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) fas1
(SPAC926.09c)		 GI:19115282 Q9UUG0
Saccharomyces cerevisiae (Sce) FAS1
(S000001665)		 GI:6322666
Kluyveromyces lactis (Kla) KLLA0B02717g GI:50303423
Eremothecium gossypii (Ego) AGOS_AER085C GI:45190691
Magnaporthe grisea (Mgr) MGG_04118 GI:145607267
Neurospora crassa (Ncr) NCU07307.1 GI:32414227


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001665
GO:0005739 mitochondrion C
IDA
SceS000001665
GO:0005811 lipid particle C
IDA
SceS000001665
GO:0005829 cytosol C
IDA
SceS000001665
SpoSPAC926.09c
GO:0005835 fatty acid synthase complex C
IDA
SceS000001665
SpoSPAC926.09c
GO:0004312 fatty acid synthase activity F
IMP
SceS000001665
GO:0004313 [acyl-carrier-protein] S-acetyltransferase
activity		 F
IDA
SceS000001665
IMP
SceS000001665
ISS
SpoSPAC926.09c
GO:0004314 [acyl-carrier-protein] S-malonyltransferase
activity		 F
IDA
SceS000001665
IMP
SceS000001665
ISS
SpoSPAC926.09c
GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein]
dehydratase activity		 F
ISS
SpoSPAC926.09c
GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH)
activity		 F
ISS
SpoSPAC926.09c
GO:0004319 enoyl-[acyl-carrier-protein] reductase (NADPH,
B-specific) activity		 F
IDA
SceS000001665
IMP
SceS000001665
GO:0004321 fatty-acyl-CoA synthase activity F
TAS
SpoSPAC926.09c
GO:0016409 palmitoyltransferase activity F
IDA
SceS000001665
IMP
SceS000001665
GO:0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase
activity		 F
IDA
SceS000001665
IMP
SceS000001665
GO:0006082 organic acid metabolic process P
RCA
SceS000001665
GO:0006417 regulation of translation P
RCA
SceS000001665
GO:0006633 fatty acid biosynthetic process P
IMP
SceS000001665
ISS
SpoSPAC926.09c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_13238

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2590 AER085C
Candida glabrata (Cgl) cgl681 CAGL0D00528g
Cryptococcus neoformans (Cne) cne3229 167.m03576
Debaryomyces hansenii (Dha) dha1044 DEHA0B08173g
Kluyveromyces lactis (Kla) kla651 KLLA0B02717g
Neurospora crassa (Ncr) ncr7113 NCU07307.2
Saccharomyces cerevisiae (Sce) sce3856 YKL182W
(S000001665)
Schizosaccharomyces pombe (Spo) spo4628 SPAC926.09c Q9UUG0
Yarrowia lipolytica (Yli) yli1365 YALI0B15059g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001665
GO:0005739 mitochondrion C
IDA
SceS000001665
GO:0005811 lipid particle C
IDA
SceS000001665
GO:0005829 cytosol C
IDA
SceS000001665
SpoSPAC926.09c
GO:0005835 fatty acid synthase complex C
IDA
SceS000001665
SpoSPAC926.09c
GO:0004312 fatty acid synthase activity F
IMP
SceS000001665
GO:0004313 [acyl-carrier-protein] S-acetyltransferase
activity		 F
IDA
SceS000001665
IMP
SceS000001665
ISS
SpoSPAC926.09c
GO:0004314 [acyl-carrier-protein] S-malonyltransferase
activity		 F
IDA
SceS000001665
IMP
SceS000001665
ISS
SpoSPAC926.09c
GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein]
dehydratase activity		 F
ISS
SpoSPAC926.09c
GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH)
activity		 F
ISS
SpoSPAC926.09c
GO:0004319 enoyl-[acyl-carrier-protein] reductase (NADPH,
B-specific) activity		 F
IDA
SceS000001665
IMP
SceS000001665
GO:0004321 fatty-acyl-CoA synthase activity F
TAS
SpoSPAC926.09c
GO:0016409 palmitoyltransferase activity F
IDA
SceS000001665
IMP
SceS000001665
GO:0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase
activity		 F
IDA
SceS000001665
IMP
SceS000001665
GO:0006082 organic acid metabolic process P
RCA
SceS000001665
GO:0006417 regulation of translation P
RCA
SceS000001665
GO:0006633 fatty acid biosynthetic process P
IMP
SceS000001665
ISS
SpoSPAC926.09c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC926.09c
(Q9UUG0)		 YKL182W
(S000001665)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001665
GO:0005739 mitochondrion C
IDA
SceS000001665
GO:0005811 lipid particle C
IDA
SceS000001665
GO:0005829 cytosol C
IDA
SceS000001665
SpoSPAC926.09c
GO:0005835 fatty acid synthase complex C
IDA
SceS000001665
SpoSPAC926.09c
GO:0004312 fatty acid synthase activity F
IMP
SceS000001665
GO:0004313 [acyl-carrier-protein] S-acetyltransferase
activity		 F
IDA
SceS000001665
IMP
SceS000001665
ISS
SpoSPAC926.09c
GO:0004314 [acyl-carrier-protein] S-malonyltransferase
activity		 F
IDA
SceS000001665
IMP
SceS000001665
ISS
SpoSPAC926.09c
GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein]
dehydratase activity		 F
ISS
SpoSPAC926.09c
GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH)
activity		 F
ISS
SpoSPAC926.09c
GO:0004319 enoyl-[acyl-carrier-protein] reductase (NADPH,
B-specific) activity		 F
IDA
SceS000001665
IMP
SceS000001665
GO:0004321 fatty-acyl-CoA synthase activity F
TAS
SpoSPAC926.09c
GO:0016409 palmitoyltransferase activity F
IDA
SceS000001665
IMP
SceS000001665
GO:0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase
activity		 F
IDA
SceS000001665
IMP
SceS000001665
GO:0006082 organic acid metabolic process P
RCA
SceS000001665
GO:0006417 regulation of translation P
RCA
SceS000001665
GO:0006633 fatty acid biosynthetic process P
IMP
SceS000001665
ISS
SpoSPAC926.09c

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