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Search term: YKL184W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SPE1
SGD link S000001667
Alternative ID YKL184W
Description Ornithine decarboxylase, catalyzes the first step in polyamine biosynthesis; degraded in a proteasome-dependent manner in the presence of excess polyamines; deletion decreases lifespan, and increases necrotic cell death and ROS generation
Synonyms YKL184W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0622 ACDHYP-

KOGs classification KOGs description
METABOLISM Ornithine decarboxylase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g14390 GI:15231844
Arabidopsis thaliana (Ath) At5g11880 GI:11357248
Caenorhabditis elegans (Cel) CE10982
(WBGene00018764)		 GI:17507535
Caenorhabditis elegans (Cel) CE12114
(WBGene00003844)		 GI:17562780 P41931
Drosophila melanogaster (Dme) 7304112 GI:7304112
Drosophila melanogaster (Dme) 7304113 GI:7304113
Homo sapiens (Hsa) Hs16506287
(ADC)		 GI:16506287 Q96L56
Homo sapiens (Hsa) Hs21361583 GI:16807144 O14977
Homo sapiens (Hsa) Hs4505489
(ODC1)		 GI:4505489 P11926
Homo sapiens (Hsa) HsM7706220 GI:7706220
Saccharomyces cerevisiae (Sce) YKL184w
(S000001667)		 GI:6322664 P08432
Schizosaccharomyces pombe (Spo) SPAC144.04c GI:19115577 Q9UQW9
Arabidopsis thaliana (Ath) At3g14390 GI:15231844
Arabidopsis thaliana (Ath) At5g11880 GI:11357248
Caenorhabditis elegans (Cel) CE10982
(WBGene00018764)		 GI:17507535
Caenorhabditis elegans (Cel) CE12114
(WBGene00003844)		 GI:17562780 P41931
Drosophila melanogaster (Dme) 7304112 GI:7304112
Drosophila melanogaster (Dme) 7304113 GI:7304113
Homo sapiens (Hsa) Hs16506287
(ADC)		 GI:16506287 Q96L56
Homo sapiens (Hsa) Hs21361583 GI:16807144 O14977
Homo sapiens (Hsa) Hs4505489
(ODC1)		 GI:4505489 P11926
Homo sapiens (Hsa) HsM7706220 GI:7706220
Saccharomyces cerevisiae (Sce) YKL184w
(S000001667)		 GI:6322664 P08432
Schizosaccharomyces pombe (Spo) SPAC144.04c GI:19115577 Q9UQW9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
HsaODC1
GO:0005634 nucleus C
IDA
SpoSPAC144.04c
GO:0005737 cytoplasm C
IDA
SceS000001667
ISS
SpoSPAC144.04c
GO:0005829 cytosol C
EXP
HsaADC
IDA
SpoSPAC144.04c
GO:0009507 chloroplast C
IDA
AthAt5g11880
GO:0004586 ornithine decarboxylase activity F
IDA
SceS000001667
ISS
SpoSPAC144.04c
TAS
HsaODC1
GO:0005515 protein binding F
IPI
HsaODC1
GO:0008792 arginine decarboxylase activity F
EXP
HsaADC
GO:0008836 diaminopimelate decarboxylase activity F
IGI
AthAt3g14390
At5g11880
ISS
AthAt5g11880
At3g14390
GO:0006596 polyamine biosynthetic process P
NAS
HsaODC1
GO:0007283 spermatogenesis P
NAS
HsaADC
GO:0009089 lysine biosynthetic process via
diaminopimelate		 P
ISS
AthAt3g14390
At5g11880
GO:0009446 putrescine biosynthetic process P
IMP
SceS000001667
ISS
SpoSPAC144.04c
GO:0009615 response to virus P
IEP
HsaODC1
GO:0015940 pantothenate biosynthetic process P
IMP
SceS000001667
ISS
SpoSPAC144.04c
GO:0019467 ornithine catabolic process, by
decarboxylation		 P
IC
SpoSPAC144.04c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1906

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ODC1 GI:4505489 P11926
Pan troglodytes (Ptr) ODC1 GI:114576085
Canis familiaris (Cfa) ODC1 GI:73979735
Mus musculus (Mmu) Odc1
(MGI:97402)		 GI:131888589 P00860
Rattus norvegicus (Rno) Odc1
(RGD:3227)		 GI:6981302 34245
Gallus gallus (Gga) ODC1 GI:118089020
Drosophila melanogaster (Dme) Odc2
(FBgn0013308)		 GI:24586474
Drosophila melanogaster (Dme) Odc1
(FBgn0013307)		 GI:24586472
Anopheles gambiae (Aga) AgaP_AGAP011805 GI:158300908
Caenorhabditis elegans (Cel) odc-1
(CE12114;
WBGene00003844)		 GI:17562780 P41931
Schizosaccharomyces pombe (Spo) spe1
(SPAC144.04c)		 GI:19115577 Q9UQW9
Saccharomyces cerevisiae (Sce) SPE1
(S000001667)		 GI:6322664 P08432
Kluyveromyces lactis (Kla) KLLA0B02673g GI:50303419
Eremothecium gossypii (Ego) AGOS_AER087C GI:45190693
Magnaporthe grisea (Mgr) MGG_02441 GI:145606246
Neurospora crassa (Ncr) NCU01271.1 GI:32412568
Oryza sativa (Osa) Os04g0136500 GI:115457000
Oryza sativa (Osa) Os09g0543400 GI:115480467
Plasmodium falciparum (Pfa) PF10_0322 GI:124802820


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
HsaODC1
PfaPF10_0322
GO:0005634 nucleus C
IDA
SpoSPAC144.04c
GO:0005737 cytoplasm C
IDA
SceS000001667
ISS
SpoSPAC144.04c
GO:0005829 cytosol C
IDA
MmuMGI:97402
SpoSPAC144.04c
GO:0004586 ornithine decarboxylase activity F
IDA
MmuMGI:97402
PfaPF10_0322
SceS000001667
ISO
MmuMGI:97402
ISS
DmeFBgn0013307
FBgn0013308
SpoSPAC144.04c
TAS
HsaODC1
GO:0005515 protein binding F
IPI
HsaODC1
GO:0001822 kidney development P
IMP
MmuMGI:97402
GO:0006595 polyamine metabolic process P
ISO
MmuMGI:97402
GO:0006596 polyamine biosynthetic process P
NAS
DmeFBgn0013308
FBgn0013307
HsaODC1
GO:0008152 metabolic process P
IDA
MmuMGI:97402
GO:0008284 positive regulation of cell proliferation P
IMP
MmuMGI:97402
GO:0009445 putrescine metabolic process P
ISS
PfaPF10_0322
GO:0009446 putrescine biosynthetic process P
IMP
SceS000001667
ISO
MmuMGI:97402
ISS
SpoSPAC144.04c
GO:0009615 response to virus P
IEP
HsaODC1
GO:0015940 pantothenate biosynthetic process P
IMP
SceS000001667
ISS
SpoSPAC144.04c
GO:0019467 ornithine catabolic process, by
decarboxylation		 P
IC
SpoSPAC144.04c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1011

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8958 ENSANGP00000008815
Anopheles gambiae (Aga) aga8956 ENSANGP00000008816
Anopheles gambiae (Aga) aga8955 ENSANGP00000020224
Ashbya gossypii (Ago) ago2592 AER087C
Caenorhabditis elegans (Cel) cel12587 K11C4.4
(CE12114;
WBGene00003844)
Candida glabrata (Cgl) cgl679 CAGL0D00484g
Cryptococcus neoformans (Cne) cne5561 179.m00420
Dictyostelium discoideum (Ddi) ddi4601 DDB0204020
Debaryomyces hansenii (Dha) dha2764 DEHA0D10549g
Drosophila melanogaster (Dme) dme3798 CG8719-PA
(FBgn0013308)
Drosophila melanogaster (Dme) dme3797 CG8721-PA
(FBgn0013307)
Danio rerio (Dre) dre27947 ENSDARP00000026811
(odc1)		 Q9DGJ4
Takifugu rubripes (Fru) fru24770 SINFRUP00000147578
Takifugu rubripes (Fru) fru12438 SINFRUP00000156319
Takifugu rubripes (Fru) fru2731 SINFRUP00000168901
Gallus gallus (Gga) gga15968 ENSGALP00000026476
(ODC1)		 P27118
Homo sapiens (Hsa) hsa17463 ENSP00000234111
(ODC1)		 P11926
Kluyveromyces lactis (Kla) kla649 KLLA0B02673g
Mus musculus (Mmu) mmu5512 ENSMUSP00000011323
(MGI:97402)		 Q3TM76
Mus musculus (Mmu) mmu18989 ENSMUSP00000023884
(MGI:2685699)		 Q3UNZ2
Mus musculus (Mmu) mmu1228 ENSMUSP00000072369
Mus musculus (Mmu) mmu20422 ENSMUSP00000079058
Mus musculus (Mmu) mmu20421 ENSMUSP00000080497
Neurospora crassa (Ncr) ncr1233 NCU01271.2
Oryza sativa (Osa) osa58425 6464.m00182
Oryza sativa (Osa) osa63223 6616.m00203
Oryza sativa (Osa) osa82115 8233.m00144
Oryza sativa (Osa) osa84994 8321.m00102
Plasmodium falciparum (Pfa) pfa540 PF10_0322
Rattus norvegicus (Rno) rno24919 ENSRNOP00000007259
(RGD:3227)		 P09057
Rattus norvegicus (Rno) rno24031 ENSRNOP00000021959
Rattus norvegicus (Rno) rno24029 ENSRNOP00000031505
(RGD:1562036)
Saccharomyces cerevisiae (Sce) sce3859 YKL184W
(S000001667)
Schizosaccharomyces pombe (Spo) spo4117 SPAC144.04c Q9UQW9
Yarrowia lipolytica (Yli) yli1073 YALI0B08162g
Yarrowia lipolytica (Yli) yli1204 YALI0B11330g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:2685699
PfaPF10_0322
GO:0005634 nucleus C
IDA
SpoSPAC144.04c
GO:0005737 cytoplasm C
IDA
SceS000001667
ISS
SpoSPAC144.04c
GO:0005829 cytosol C
IDA
MmuMGI:97402
SpoSPAC144.04c
GO:0003674 molecular_function F
ND
MmuMGI:2685699
GO:0004586 ornithine decarboxylase activity F
IDA
MmuMGI:97402
PfaPF10_0322
SceS000001667
ISO
MmuMGI:97402
ISS
DmeFBgn0013307
FBgn0013308
SpoSPAC144.04c
GO:0001822 kidney development P
IMP
MmuMGI:97402
GO:0006595 polyamine metabolic process P
ISO
MmuMGI:97402
GO:0006596 polyamine biosynthetic process P
NAS
DmeFBgn0013308
FBgn0013307
GO:0008150 biological_process P
ND
MmuMGI:2685699
GO:0008152 metabolic process P
IDA
MmuMGI:97402
GO:0008284 positive regulation of cell proliferation P
IMP
MmuMGI:97402
GO:0009445 putrescine metabolic process P
ISS
PfaPF10_0322
GO:0009446 putrescine biosynthetic process P
IMP
SceS000001667
ISO
MmuMGI:97402
ISS
SpoSPAC144.04c
GO:0015940 pantothenate biosynthetic process P
IMP
SceS000001667
ISS
SpoSPAC144.04c
GO:0019467 ornithine catabolic process, by
decarboxylation		 P
IC
SpoSPAC144.04c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC144.04c
(Q9UQW9)		 YKL184W
(S000001667)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC144.04c
GO:0005737 cytoplasm C
IDA
SceS000001667
ISS
SpoSPAC144.04c
GO:0005829 cytosol C
IDA
SpoSPAC144.04c
GO:0004586 ornithine decarboxylase activity F
IDA
SceS000001667
ISS
SpoSPAC144.04c
GO:0009446 putrescine biosynthetic process P
IMP
SceS000001667
ISS
SpoSPAC144.04c
GO:0015940 pantothenate biosynthetic process P
IMP
SceS000001667
ISS
SpoSPAC144.04c
GO:0019467 ornithine catabolic process, by
decarboxylation		 P
IC
SpoSPAC144.04c

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk