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Search term: YKL189W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HYM1
SGD link S000001672
Alternative ID YKL189W
Description Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response
Synonyms YKL189W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1566 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Conserved protein Mo25

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g03410 GI:15227629
Arabidopsis thaliana (Ath) At4g17270 GI:15236013
Arabidopsis thaliana (Ath) At5g18940 GI:15239613
Arabidopsis thaliana (Ath) At5g47540 GI:15238126
Caenorhabditis elegans (Cel) CE14890
(WBGene00013140)		 GI:17537411 O18211
Caenorhabditis elegans (Cel) CE19605
(WBGene00020858)		 GI:17509287 Q9TZM2
Caenorhabditis elegans (Cel) CE28410_2 GI:17569177
Drosophila melanogaster (Dme) 7294077
(FBgn0017572)		 GI:17647657
Homo sapiens (Hsa) Hs13569887 GI:13569887
Homo sapiens (Hsa) Hs7706481 GI:7706481 Q9Y376
Saccharomyces cerevisiae (Sce) YKL189w
(S000001672)		 GI:6322659 P32464
Schizosaccharomyces pombe (Spo) SPAC1834.06c GI:19115597 Q9P7Q8


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000001672
GO:0005575 cellular_component C
ND
AthAt5g18940
At2g03410
DmeFBgn0017572
GO:0005622 intracellular C
IDA
SceS000001672
GO:0005634 nucleus C
IDA
SpoSPAC1834.06c
GO:0005737 cytoplasm C
IDA
SpoSPAC1834.06c
GO:0005816 spindle pole body C
IDA
SpoSPAC1834.06c
GO:0005826 actomyosin contractile ring C
IDA
SpoSPAC1834.06c
GO:0005829 cytosol C
IDA
SpoSPAC1834.06c
GO:0005886 plasma membrane C
IDA
AthAt4g17270
GO:0005933 cellular bud C
IDA
SceS000001672
GO:0031097 medial cortex C
IDA
SpoSPAC1834.06c
GO:0032153 cell division site C
IDA
SpoSPAC1834.06c
GO:0043332 mating projection tip C
IDA
SceS000001672
GO:0051286 cell tip C
IDA
SpoSPAC1834.06c
GO:0003674 molecular_function F
ND
SceS000001672
GO:0005515 protein binding F
IPI
SpoSPAC1834.06c
GO:0000003 reproduction P
IMP
CelWBGene00013140
GO:0000078 cell shape checkpoint P
NAS
SpoSPAC1834.06c
GO:0001700 embryonic development via the syncytial
blastoderm		 P
IMP
DmeFBgn0017572
GO:0007109 cytokinesis, completion of separation P
IMP
SceS000001672
GO:0007118 budding cell apical bud growth P
IGI
SceS000001672
IMP
SceS000001672
GO:0007163 establishment or maintenance of cell
polarity		 P
IGI
SpoSPAC1834.06c
GO:0008150 biological_process P
ND
AthAt4g17270
At5g18940
At2g03410
At5g47540
GO:0008360 regulation of cell shape P
IGI
SceS000001672
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00013140
GO:0010590 regulation of cytokinetic cell
separation		 P
IMP
SpoSPAC1834.06c
GO:0019953 sexual reproduction P
RCA
SceS000001672
GO:0030037 actin filament reorganization involved in cell
cycle		 P
IMP
SpoSPAC1834.06c
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity		 P
TAS
SpoSPAC1834.06c
GO:0032878 regulation of establishment or maintenance of cell
polarity		 P
IMP
SpoSPAC1834.06c
GO:0034613 cellular protein localization P
IGI
SpoSPAC1834.06c
GO:0040011 locomotion P
IMP
CelWBGene00013140
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00013140
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00013140
GO:0045449 regulation of transcription P
IMP
SceS000001672
GO:0045859 regulation of protein kinase activity P
IMP
SpoSPAC1834.06c
GO:0051666 actin cortical patch localization P
IMP
SpoSPAC1834.06c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68798

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) HYM1
(S000001672)		 GI:6322659 P32464
Kluyveromyces lactis (Kla) KLLA0B02519g GI:50303405
Eremothecium gossypii (Ego) AGOS_AER093C GI:45190699


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000001672
GO:0005622 intracellular C
IDA
SceS000001672
GO:0005933 cellular bud C
IDA
SceS000001672
GO:0043332 mating projection tip C
IDA
SceS000001672
GO:0003674 molecular_function F
ND
SceS000001672
GO:0007109 cytokinesis, completion of separation P
IMP
SceS000001672
GO:0007118 budding cell apical bud growth P
IGI
SceS000001672
IMP
SceS000001672
GO:0008360 regulation of cell shape P
IGI
SceS000001672
GO:0019953 sexual reproduction P
RCA
SceS000001672
GO:0045449 regulation of transcription P
IMP
SceS000001672

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1054

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15489 ENSANGP00000021363
Anopheles gambiae (Aga) aga8060 ENSANGP00000023148
Ashbya gossypii (Ago) ago2598 AER093C
Arabidopsis thaliana (Ath) ath19587 At4g17270.1
Arabidopsis thaliana (Ath) ath24157 At5g18940.1
Arabidopsis thaliana (Ath) ath24158 At5g18940.2
Arabidopsis thaliana (Ath) ath26635 At5g47540.1
Caenorhabditis elegans (Cel) cel13193 R02E12.2a
(CE28410;
WBGene00019827)
Caenorhabditis elegans (Cel) cel13194 R02E12.2b
(CE04779)
Caenorhabditis elegans (Cel) cel19597 Y53C12A.4
(CE14890;
WBGene00013140)
Candida glabrata (Cgl) cgl672 CAGL0D00330g
Cryptococcus neoformans (Cne) cne4359 177.m03112
Dictyostelium discoideum (Ddi) ddi9101 DDB0218587
Dictyostelium discoideum (Ddi) ddi9102 DDB0218588
Debaryomyces hansenii (Dha) dha2638 DEHA0D07711g
Drosophila melanogaster (Dme) dme9851 CG4083-PA
(FBgn0017572)
Danio rerio (Dre) dre975 ENSDARP00000000723
Danio rerio (Dre) dre5679 ENSDARP00000014384
(cab39)		 Q803V8
Danio rerio (Dre) dre6737 ENSDARP00000028035
Takifugu rubripes (Fru) fru18557 SINFRUP00000129626
Takifugu rubripes (Fru) fru4177 SINFRUP00000137605
Takifugu rubripes (Fru) fru18223 SINFRUP00000137809
Gallus gallus (Gga) gga23269 ENSGALP00000008858
Gallus gallus (Gga) gga2980 ENSGALP00000027417
(CAB39L)
Homo sapiens (Hsa) hsa19439 ENSP00000258418
(CAB39)		 Q9Y376
Homo sapiens (Hsa) hsa8789 ENSP00000261669
(CAB39L)		 Q9H9S4
Homo sapiens (Hsa) hsa8787 ENSP00000348113
(CAB39L)		 Q9H9S4
Homo sapiens (Hsa) hsa8788 ENSP00000349191
Kluyveromyces lactis (Kla) kla642 KLLA0B02519g
Mus musculus (Mmu) mmu8308 ENSMUSP00000022553
(MGI:1914081)		 Q9DB16-1
Mus musculus (Mmu) mmu672 ENSMUSP00000069639
Mus musculus (Mmu) mmu673 ENSMUSP00000080789
(MGI:107438)		 Q8K312
Neurospora crassa (Ncr) ncr3467 NCU03576.2
Oryza sativa (Osa) osa21718 3659.m00165
Oryza sativa (Osa) osa30307 4308.m00092
Oryza sativa (Osa) osa54167 6057.m00146
Oryza sativa (Osa) osa66346 6891.m00097
Rattus norvegicus (Rno) rno11476 ENSRNOP00000016162
(RGD:1308945)		 Q5XIJ7
Rattus norvegicus (Rno) rno30377 ENSRNOP00000023303
(RGD:1306390)
Saccharomyces cerevisiae (Sce) sce3864 YKL189W
(S000001672)
Schizosaccharomyces pombe (Spo) spo4648 SPAC1834.06c Q9P7Q8
Yarrowia lipolytica (Yli) yli2757 YALI0D01199g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000001672
GO:0005575 cellular_component C
ND
AthAt5g18940
DmeFBgn0017572
MmuMGI:1914081
GO:0005622 intracellular C
IDA
SceS000001672
GO:0005634 nucleus C
IDA
SpoSPAC1834.06c
GO:0005737 cytoplasm C
IDA
SpoSPAC1834.06c
GO:0005816 spindle pole body C
IDA
SpoSPAC1834.06c
GO:0005826 actomyosin contractile ring C
IDA
SpoSPAC1834.06c
GO:0005829 cytosol C
IDA
SpoSPAC1834.06c
GO:0005886 plasma membrane C
IDA
AthAt4g17270
GO:0005933 cellular bud C
IDA
SceS000001672
GO:0031097 medial cortex C
IDA
SpoSPAC1834.06c
GO:0032153 cell division site C
IDA
SpoSPAC1834.06c
GO:0043234 protein complex C
ISO
MmuMGI:107438
GO:0043332 mating projection tip C
IDA
SceS000001672
GO:0051286 cell tip C
IDA
SpoSPAC1834.06c
GO:0003674 molecular_function F
ND
MmuMGI:1914081
SceS000001672
GO:0004674 protein serine/threonine kinase
activity		 F
ISO
MmuMGI:107438
GO:0005509 calcium ion binding F
ISS
MmuMGI:107438
GO:0005515 protein binding F
IPI
SpoSPAC1834.06c
GO:0000003 reproduction P
IMP
CelWBGene00013140
GO:0000078 cell shape checkpoint P
NAS
SpoSPAC1834.06c
GO:0001700 embryonic development via the syncytial
blastoderm		 P
IMP
DmeFBgn0017572
GO:0007109 cytokinesis, completion of separation P
IMP
SceS000001672
GO:0007118 budding cell apical bud growth P
IGI
SceS000001672
IMP
SceS000001672
GO:0007163 establishment or maintenance of cell
polarity		 P
IGI
SpoSPAC1834.06c
GO:0008150 biological_process P
ND
AthAt4g17270
At5g18940
At5g47540
MmuMGI:1914081
GO:0008360 regulation of cell shape P
IGI
SceS000001672
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00013140
GO:0010590 regulation of cytokinetic cell
separation		 P
IMP
SpoSPAC1834.06c
GO:0019953 sexual reproduction P
RCA
SceS000001672
GO:0030037 actin filament reorganization involved in cell
cycle		 P
IMP
SpoSPAC1834.06c
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity		 P
TAS
SpoSPAC1834.06c
GO:0032878 regulation of establishment or maintenance of cell
polarity		 P
IMP
SpoSPAC1834.06c
GO:0034613 cellular protein localization P
IGI
SpoSPAC1834.06c
GO:0040011 locomotion P
IMP
CelWBGene00013140
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00013140
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00013140
GO:0045449 regulation of transcription P
IMP
SceS000001672
GO:0045859 regulation of protein kinase activity P
IMP
SpoSPAC1834.06c
GO:0051291 protein heterooligomerization P
ISO
MmuMGI:107438
GO:0051666 actin cortical patch localization P
IMP
SpoSPAC1834.06c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1834.06c
(Q9P7Q8)		 YKL189W
(S000001672)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000001672
GO:0005622 intracellular C
IDA
SceS000001672
GO:0005634 nucleus C
IDA
SpoSPAC1834.06c
GO:0005737 cytoplasm C
IDA
SpoSPAC1834.06c
GO:0005816 spindle pole body C
IDA
SpoSPAC1834.06c
GO:0005826 actomyosin contractile ring C
IDA
SpoSPAC1834.06c
GO:0005829 cytosol C
IDA
SpoSPAC1834.06c
GO:0005933 cellular bud C
IDA
SceS000001672
GO:0031097 medial cortex C
IDA
SpoSPAC1834.06c
GO:0032153 cell division site C
IDA
SpoSPAC1834.06c
GO:0043332 mating projection tip C
IDA
SceS000001672
GO:0051286 cell tip C
IDA
SpoSPAC1834.06c
GO:0003674 molecular_function F
ND
SceS000001672
GO:0005515 protein binding F
IPI
SpoSPAC1834.06c
GO:0000078 cell shape checkpoint P
NAS
SpoSPAC1834.06c
GO:0007109 cytokinesis, completion of separation P
IMP
SceS000001672
GO:0007118 budding cell apical bud growth P
IGI
SceS000001672
IMP
SceS000001672
GO:0007163 establishment or maintenance of cell
polarity		 P
IGI
SpoSPAC1834.06c
GO:0008360 regulation of cell shape P
IGI
SceS000001672
GO:0010590 regulation of cytokinetic cell
separation		 P
IMP
SpoSPAC1834.06c
GO:0019953 sexual reproduction P
RCA
SceS000001672
GO:0030037 actin filament reorganization involved in cell
cycle		 P
IMP
SpoSPAC1834.06c
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity		 P
TAS
SpoSPAC1834.06c
GO:0032878 regulation of establishment or maintenance of cell
polarity		 P
IMP
SpoSPAC1834.06c
GO:0034613 cellular protein localization P
IGI
SpoSPAC1834.06c
GO:0045449 regulation of transcription P
IMP
SceS000001672
GO:0045859 regulation of protein kinase activity P
IMP
SpoSPAC1834.06c
GO:0051666 actin cortical patch localization P
IMP
SpoSPAC1834.06c

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s.khadayate@ucl.ac.uk