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Search term: YKL195W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MIA40
SGD link S000001678
Alternative ID YKL195W
Description Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins
Synonyms YKL195W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4149 -C-HYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved protein

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE00164
(WBGene00018366)
GI:17553400 P34415
Caenorhabditis elegans (Cel) CE03186
(WBGene00008690)
GI:17551584 Q19342
Caenorhabditis elegans (Cel) CE26350
(WBGene00022773)
GI:17544608 Q9N4N2
Caenorhabditis elegans (Cel) CE26351
(WBGene00022772)
GI:17544606 Q9N4N1
Homo sapiens (Hsa) Hs21389469 GI:16551623 Q8N4Q1
Saccharomyces cerevisiae (Sce) YKL195w
(S000001678)
GI:6322653
Schizosaccharomyces pombe (Spo) SPAC57A10.11c GI:19114228 P87059


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001678
SpoSPAC57A10.11c
GO:0005742 mitochondrial outer membrane translocase
complex
C
IDA
SceS000001678
GO:0005743 mitochondrial inner membrane C
IDA
SceS000001678
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000001678
GO:0042721 mitochondrial inner membrane protein insertion
complex
C
ISS
SpoSPAC57A10.11c
GO:0003674 molecular_function F
ND
SceS000001678
SpoSPAC57A10.11c
GO:0006461 protein complex assembly P
RCA
SceS000001678
GO:0045041 protein import into mitochondrial intermembrane
space
P
IMP
SceS000001678
IPI
SceS000001678
ISS
SpoSPAC57A10.11c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
14846

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CHCHD4 GI:148612859
Pan troglodytes (Ptr) CHCHD4 GI:114585525
Canis familiaris (Cfa) CHCHD4 GI:57100869
Mus musculus (Mmu) Chchd4
(MGI:1919420)
GI:19527144 Q8VEA4
Rattus norvegicus (Rno) Chchd4
(RGD:1310746)
GI:61740629
Gallus gallus (Gga) CHCHD4 GI:50754423
Drosophila melanogaster (Dme) CG7950
(FBgn0039745)
GI:24651291
Anopheles gambiae (Aga) AgaP_AGAP002940 GI:118781942
Saccharomyces cerevisiae (Sce) MIA40
(S000001678)
GI:37362671
Kluyveromyces lactis (Kla) KLLA0D02706g GI:50306429


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1919420
GO:0005739 mitochondrion C
IDA
MmuMGI:1919420
SceS000001678
GO:0005742 mitochondrial outer membrane translocase
complex
C
IDA
SceS000001678
GO:0005743 mitochondrial inner membrane C
IDA
SceS000001678
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000001678
GO:0003674 molecular_function F
ND
MmuMGI:1919420
SceS000001678
GO:0006461 protein complex assembly P
RCA
SceS000001678
GO:0008150 biological_process P
ND
MmuMGI:1919420
GO:0045041 protein import into mitochondrial intermembrane
space
P
IMP
SceS000001678
IPI
SceS000001678

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2764

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga5187 ENSANGP00000023760
Ashbya gossypii (Ago) ago2613 AER108C
Arabidopsis thaliana (Ath) ath24585 At5g23395.1
Caenorhabditis elegans (Cel) cel6012 F11C1.1
(CE03186;
WBGene00008690)
Caenorhabditis elegans (Cel) cel22041 ZK616.3
(CE26350;
WBGene00022773)
Candida glabrata (Cgl) cgl813 CAGL0D03520g
Cryptococcus neoformans (Cne) cne3223 167.m03570
Debaryomyces hansenii (Dha) dha2687 DEHA0D08866g
Drosophila melanogaster (Dme) dme15165 CG7950-PA
(FBgn0039745)
Drosophila melanogaster (Dme) dme15166 CG7950-PB
(FBgn0039745)
Danio rerio (Dre) dre13247 ENSDARP00000003467
Danio rerio (Dre) dre13251 ENSDARP00000039846
(LOC573061)
Takifugu rubripes (Fru) fru5599 SINFRUP00000145658
Takifugu rubripes (Fru) fru5670 SINFRUP00000157387
Gallus gallus (Gga) gga5299 ENSGALP00000010217
(CHCHD4)
Homo sapiens (Hsa) hsa22117 ENSP00000295767
(CHCHD4)
Q8N4Q1-2
Kluyveromyces lactis (Kla) kla2187 KLLA0D02706g
Mus musculus (Mmu) mmu22358 ENSMUSP00000041380
(MGI:1919420)
Q8VEA4
Mus musculus (Mmu) mmu29300 ENSMUSP00000065006
Neurospora crassa (Ncr) ncr4805 NCU04945.2
Oryza sativa (Osa) osa44597 5341.m00153
Rattus norvegicus (Rno) rno21862 ENSRNOP00000038359
(RGD:1310746)
Q5BJN5
Rattus norvegicus (Rno) rno31553 ENSRNOP00000039236
(GI:501576)
Q0VGA2
Rattus norvegicus (Rno) rno3973 ENSRNOP00000045402
(RGD:1310746)
Q5BJN5
Rattus norvegicus (Rno) rno30100 ENSRNOP00000048229
(GI:685505)
Saccharomyces cerevisiae (Sce) sce3870 YKL195W
(S000001678)
Schizosaccharomyces pombe (Spo) spo4227 SPAC57A10.11c P87059
Yarrowia lipolytica (Yli) yli4745 YALI0E21373g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1919420
GO:0005739 mitochondrion C
IDA
MmuMGI:1919420
SceS000001678
SpoSPAC57A10.11c
GO:0005742 mitochondrial outer membrane translocase
complex
C
IDA
SceS000001678
GO:0005743 mitochondrial inner membrane C
IDA
SceS000001678
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000001678
GO:0042721 mitochondrial inner membrane protein insertion
complex
C
ISS
SpoSPAC57A10.11c
GO:0003674 molecular_function F
ND
AthAt5g23395
MmuMGI:1919420
SceS000001678
SpoSPAC57A10.11c
GO:0006461 protein complex assembly P
RCA
SceS000001678
GO:0008150 biological_process P
ND
AthAt5g23395
MmuMGI:1919420
GO:0045041 protein import into mitochondrial intermembrane
space
P
IMP
SceS000001678
IPI
SceS000001678
ISS
SpoSPAC57A10.11c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC57A10.11c
(P87059)
YKL195W
(S000001678)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000001678
SpoSPAC57A10.11c
GO:0005742 mitochondrial outer membrane translocase
complex
C
IDA
SceS000001678
GO:0005743 mitochondrial inner membrane C
IDA
SceS000001678
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000001678
GO:0042721 mitochondrial inner membrane protein insertion
complex
C
ISS
SpoSPAC57A10.11c
GO:0003674 molecular_function F
ND
SceS000001678
SpoSPAC57A10.11c
GO:0006461 protein complex assembly P
RCA
SceS000001678
GO:0045041 protein import into mitochondrial intermembrane
space
P
IMP
SceS000001678
IPI
SceS000001678
ISS
SpoSPAC57A10.11c

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GO info in one table:

s.khadayate@ucl.ac.uk